Repetibilidad y reproducibilidad de las medidas del espesor y curvatura corneal obtenidas mediante el pentacam HR(OCULUS)

Tesis (Optometra). -- Universidad de La Salle, Facultad de Ciencias de La Salud. Programa de Optometria, 2014

Relación entre la ambliopia moderada y severa y el desarrollo según la escala abreviada de desarrollo (EAD II), en niños de 3 a 7 años

Tesis (Optometra). -- Universidad de La Salle, Facultad de Ciencias de La Salud. Programa de Optometria, 2014

Memorias seminario internacional de investigación e innovación en ciencias de la visión temática : nuevas tecnologías y cuidado primario

Tesis (Optometra). -- Universidad de La Salle, Facultad de Ciencias de La Salud. Programa de Optometria, 2014

Factores asociados al diagnóstico tardío de la ambliopía en niños de 4 a 12 años de edad en la ciudad de Bogotá

Tesis (Optómetra). -- Universidad de La Salle, Facultad de Ciencias de La Salud. Programa de Optometría, 2014

Resultados sensíveis em enfermagem para a população pediatrica

Relatório de estagio apresentado para a obtenção do grau de Mestre em Enfermagem de Saúde da Criança e do Jovem

Automatic Counting of Microglial Cells in Healthy and Glaucomatous Mouse Retinas

Proliferation of microglial cells has been considered a sign of glial activation and a hallmark of ongoing neurodegenerative diseases. Microglia activation is analyzed in animal models of different eye diseases. Numerous retinal samples are required for each of these studies to obtain relevant data of statistical significance. Because manual quantification of microglial cells is time consuming, the aim of this study was develop an algorithm for automatic identification of retinal microglia. Two groups of adult male Swiss mice were used: age-matched controls (naïve, n = 6) and mice subjected to unilateral laser-induced ocular hypertension (lasered; n = 9). In the latter group, both hypertensive eyes and contralateral untreated retinas were analyzed. Retinal whole mounts were immunostained with anti Iba-1 for detecting microglial cell populations. A new algorithm was developed in MATLAB for microglial quantification; it enabled the quantification of microglial cells in the inner and outer plexiform layers and evaluates the area of the retina occupied by Iba-1+ microglia in the nerve fiber-ganglion cell layer. The automatic method was applied to a set of 6,000 images. To validate the algorithm, mouse retinas were evaluated both manually and computationally; the program correctly assessed the number of cells (Pearson correlation R = 0.94 and R = 0.98 for the inner and outer plexiform layers respectively). Statistically significant differences in glial cell number were found between naïve, lasered eyes and contralateral eyes (P<0.05, naïve versus contralateral eyes; P<0.001, naïve versus lasered eyes and contralateral versus lasered eyes). The algorithm developed is a reliable and fast tool that can evaluate the number of microglial cells in naïve mouse retinas and in retinas exhibiting proliferation. The implementation of this new automatic method can enable faster quantification of microglial cells in retinal pathologies.

Pseudoangiomatous Stromal Hyperplasia in Pediatric Age: A Case Report and Review of Literature

Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign disease, characterized by abnormal proliferation of fibroglandular stroma. It was first described in 1986. The authors present a case of a twelve year-old girl with a history of kidney transplantation due to nephrotic syndrome with rapidly progressive and painful breast asymmetry with approximately six months duration. No lymphadenopathy or other signs or symptoms were associated. Ultrasound didn’t reveal specific findings. Breast magnetic resonance (MR) showed a massive heterogeneous nodular mass with regular contours and contrast enhancement. Given the degree of breast asymmetry as well as the patient’s symptoms, surgical excision of the tumor was preferred over core biopsy. Histopathological and immunohistochemical examination showed pseudoangiomatous stromal hyperplasia. The authors describe the clinical presentation, imaging and histological features as well as therapeutic approach in these patients

Intraexaminer repeatability and agreement in stereoacuity measurements made in young adults

·AIM: To determine the repeatability and agreement of stereoacuity measurements made using some of the most widely used clinical tests: Frisby, TNO, Randot and Titmus. ·METHODS: Stereoacuity was measured in two different sessions separated by a time interval of at least 24h but no longer than 1wk in 74 subjects of mean age 20.6y using the four methods. The study participants were divided into two groups: subjects with normal binocular vision and subjects with abnormal binocular vision. ·RESULTS: Best repeatability was shown by the Frisby and Titmus [coefficient of repeatability (COR): 依13 and 依12s arc respectively] in the subjects with normal binocular vision though a clear ceiling effect was noted. In the subjects with abnormal binocular vision, best repeatability was shown by the Frisby (COR: 依69s arc) and Randot (COR: 依72s arc). In both groups, the TNO test showed poorest agreement with the other tests. ·CONCLUSION: Therepeatabilityof stereoacuitymeasures was low in subjects with poor binocular vision yet fairly good in subjects with normal binocular vision with the exception of the TNO test. The reduced agreement detected between the tests indicates they cannot be used interchangeably.

Phenomenological model of visual acuity

We propose in this work a model for describing visual acuity (VV) as a function of defocus and pupil diameter. Although the model is mainly based on geometrical optics, it also incorporates nongeometrical effects phenomenologically. Compared to similar visual acuity models, the proposed one considers the effect of astigmatism and the variability of best corrected VV among individuals; it also takes into account the accommodation and the “tolerance to defocus,” the latter through a phenomenological parameter. We have fitted the model to the VV data provided in the works of Holladay et al. and Peters, showing the ability of this model to accurately describe the variation of VV against blur and pupil diameter. We have also performed a comparison between the proposed model and others previously published in the literature. The model is mainly intended for use in the design of ophthalmic compensations, but it can also be useful in other fields such as visual ergonomics, design of visual tests, and optical instrumentation.

Accommodative changes produced in response to overnight orthokeratology

Background To evaluate short-term (3 months) and long-term (3 years) accommodative changes produced by overnight orthokeratology (OK). Methods A prospective, longitudinal study on young adult subjects with low to moderate myopia was carried out. A total of 93 patients took part in the study. Out of these, 72 were enrolled into the short-term follow-up: 21 were on a control group, 26 on a Paragon CRT contact lenses group, and 25 on a Seefree contact lenses group. The other 21 patients were old CRT wearers on long-term follow-up. Accommodative function was assessed by means of negative and positive relative accommodation (NRA / PRA), monocular accommodative amplitude (MAA), accommodative lag, and monocular accommodative facility (MAF). These values were compared among the three short-term groups at the follow-up visit. The long- and short-term follow-up data was compared among the CRT groups. Results Subjective accommodative results did not suffer any statistically significant changes in any of the accommodative tests for any of the short-term groups when compared to baseline. There were no statistically significant differences between the three short-term groups at the follow-up visit. When comparing the short- and long-term groups, only the NRA showed a significant difference (p = 0.0006) among all the accommodation tests. Conclusions OK does not induce changes in the ocular accommodative function for either short-term or long-term periods.

Prevalência de sobrepeso e de obesidade em crianças e adolescentes na Região Autónoma da Madeira, Portugal

O objectivo foi estimar a prevalência de sobrepeso e obesi dade em crianças e adolescentes da Região Autónoma da Madeira, Portugal. Um procedimento estratificado proporcional foi usado para obter uma amostra representativa de crianças e adolescentes madeirenses dos 7 aos 18 anos. No total, 2503 sujeitos, 1266 rapazes e 1237 raparigas, participaram no estudo. A prevalência de sobrepeso e obesidade foi definida a partir do índice de massa corporal e de acordo com os pontos de corte propostos pela ‘International Obesity TaskForce’. A prevalência de sobrepeso foi de 14.22% e 10.99% para os rapazes e raparigas dos 7-18 anos, respectivamente. Os valores correspondentes para a obesidade foram 2.61% e 1.86%. Na maioria dos grupos etários, os elementos do sexo mas culino apresentaram uma prevalência mais elevada de sobrepeso e obesidade do que o sexo feminino. Percentagens mais baixas ou ausência de sobrepeso e obesidade foram obser vadas aos 16-17 anos. A prevalência de sobrepeso e obesid ade para as crianças e adolescentes madeirenses foi similar ou inferior a pesquisas desenvolvidas em Portugal e em outros países europeus. A prevalência de sobrepeso e obesidade, embora baixa, requer prevenção adequada.

Resultados sensíveis em enfermagem para a população pediatrica

Relatório de estagio apresentado para a obtenção do grau de Mestre em Enfermagem de Saúde da Criança e do Jovem

Ingestão proteica na infância e risco de obesidade

Trabalho Complementar apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de licenciada em Ciências da Nutrição

Prevalência de sobrepeso e de obesidade em crianças e adolescentes na Região Autónoma da Madeira, Portugal

O objectivo foi estimar a prevalência de sobrepeso e obesi dade em crianças e adolescentes da Região Autónoma da Madeira, Portugal. Um procedimento estratificado proporcional foi usado para obter uma amostra representativa de crianças e adolescentes madeirenses dos 7 aos 18 anos. No total, 2503 sujeitos, 1266 rapazes e 1237 raparigas, participaram no estudo. A prevalência de sobrepeso e obesidade foi definida a partir do índice de massa corporal e de acordo com os pontos de corte propostos pela ‘International Obesity TaskForce’. A prevalência de sobrepeso foi de 14.22% e 10.99% para os rapazes e raparigas dos 7-18 anos, respectivamente. Os valores correspondentes para a obesidade foram 2.61% e 1.86%. Na maioria dos grupos etários, os elementos do sexo mas culino apresentaram uma prevalência mais elevada de sobrepeso e obesidade do que o sexo feminino. Percentagens mais baixas ou ausência de sobrepeso e obesidade foram obser vadas aos 16-17 anos. A prevalência de sobrepeso e obesid ade para as crianças e adolescentes madeirenses foi similar ou inferior a pesquisas desenvolvidas em Portugal e em outros países europeus. A prevalência de sobrepeso e obesidade, embora baixa, requer prevenção adequada.

Celiac disease in children from Madeira island and its prevalence in first degree relatives

Context - It is well recognized that celiac disease is an immune-mediated systemic disorder highly prevalent among relatives of celiac patients. Objectives - The aim of this study is to determine the prevalence of celiac disease in a group of first degree relatives of celiac children, and to access the frequency of human leukocyte antigen HLA-DQ2 and DQ8 in celiac disease patients and their affected relatives. Methods - A survey was conducted of 39 children with celiac disease with follow-up in the Pediatric outpatient’s clinic of Dr. Nélio Mendonça Hospital, in Madeira Island, Portugal. Were invited 110 first degree relatives to undergo serological screen for celiac disease with IgA antibody to human recombinant tissue transglutaminase (IgA-TGG) quantification. In all seropositive relatives, small intestinal biopsy and HLA typing was recommended. Results - HLA- typing was performed in 38 celiac patients, 28/74% DQ2 positive, 1/2% DQ8 positive and 9/24% incomplete DQ2. Positive IgA-TGG was found in five out of the 95 relatives, and CD was diagnosed in three of them. Three relatives had the presence of HLA-DQ2, two were DQ2 incomplete (DQB1*02). Conclusion - The prevalence of celiac disease among first degree celiac patients´ relatives was 3.1%, 4.5 times higher than the general Portuguese population (0,7%) witch reinforces the need of extensive diagnostic screening in this specific group. HLA-DQ2 typing may be a tool in the diagnostic approach.