993 resultados para Mi, Fu, 1051-1107.
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El autor reflexiona sobre el poema escrito por Bolívar en 1823. Plantea que, ante la sobrecogedora belleza del volcán, y enfrentado a un destino complejo y caótico, el héroe revive eternos temores. Serrano lo asimila al Cristo del sermón de la montaña, cuando pretende reencontrarse con los elementos, reinsertarse en el mundo que está redefiniéndose en los campos de batalla. En la cima del Chimborazo, Bolívar dialoga con el tiempo, voz en la que el autor destaca las resonancias bíblicas. Resalta que el héroe, perturbado por los acontecimientos políticos, está poseído por una “pasión violenta”, por un proyecto político que deviene en obsesión: la idea de construir una gran nación liberada. Serrano concibe a la voz del Viejo como la representante de un orden mítico que pervive (el guardián del mundo mineral y espiritual), que interpela a un sujeto que, otra vez como el Cristo, duda. El final abierto del texto, para el autor, sugiere que solo en el sueño o el delirio es posible reconocer nuestra condición de “míseros mortales”.
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Uno de los principales objetivos del Programa Escuelas Lectoras desarrollado por la Universidad Andina Simón Bolívar, Sede Ecuador, en el marco del Proyecto CECM, es desarrollar en los niños y las niñas la habilidad para producir textos escritos de manera autónoma y creativa. Para ello, los y las docentes ponen en práctica en el aula una estrategia de producción escrita que consiste de cuatro pasos: planifi cación, textualización, revisión y publicación. Durante el año lectivo 2008 – 2009, los niños y las niñas de las escuelas que forman parte de la Red de Escuelas por el Mejoramiento de la Calidad de la Educación Básica, impulsada por el Programa Escuelas Lectoras, tuvieron la oportunidad de participar en un concurso de cuento con producciones propias y originales. Este libro presenta los cuentos ganadores del concurso, en los cuales se puede apreciar la calidad de expresión escrita alcanzada por los y las estudiantes de segundo a séptimo años de educación básica. Paralelamente se realizó un concurso de fotografía con el tema “El placer de leer”, cuyas fotos ganadoras también se presentan en esta publicación.
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La presente investigación busca analizar a partir de las prácticas socio-culturales de las personas sordas,cómo en nuestra sociedad occidental operan los denominados regímenes discursivos sonoro visualescomo formas estructurantes de la realidad, los cuales constituyen sistemas de jerarquización y valoración, desde donde se produce la subalternizaciónde ciertas formas de percibir el mundo, ciertos saberes, ciertas formas comunicativas –como la lengua de señas-, además de la estigmatización de algunos grupos –como el caso de la comunidad de personas sordas- sobre los cuales se ejerce poder para operar, afianzarse y legitimarse a sí mismos como sistemas dominantes.
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The Military Intelligence (Research) Department of the British War Office was tasked in 1940 with encouraging and supporting armed resistance in occupied Europe and the Axis-controlled Middle East. The major contention of this paper is that, in doing so, MI(R) performed a key role in British strategy in 1940-42 and in the development of what are now known as covert operations. MI(R) developed an organic, but coherent doctrine for such activity which was influential upon the Special Operations Executive (SOE) and its own sub-branch, G(R), which applied this doctrine in practice in East Africa and the Middle East in 1940-41. It was also here that a number of key figures in the development of covert operations and special forces first cut their teeth, the most notable being Major Generals Colin Gubbins and Orde Wingate.
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The mammalian lignan, enterolactone, has been shown to reduce the proliferation of the earlier stages of prostate cancer at physiological concentrations in vitro. However, efficacy in the later stages of the disease occurs at concentrations difficult to achieve through dietary modification. We have therefore investigated what concentration(s) of enterolactone can restrict proliferation in multiple stages of prostate cancer using an in vitro model system of prostate disease. We determined that enterolactone at 20 μM significantly restricted the proliferation of mid and late stage models of prostate disease. These effects were strongly associated with changes in the expression of the DNA licencing genes (GMNN, CDT1, MCM2 and 7), in reduced expression of the miR-106b cluster (miR-106b, miR-93, and miR-25), and in increased expression of the PTEN tumour suppressor gene. We have shown anti-proliferative effects of enterolactone in earlier stages of prostate disease than previously reported and that these effects are mediated, in part, by microRNA-mediated regulation.
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Purpose: Exercise training restores innate immune system cell function in post-myocardial infarction (post-MI) rats. However, studies of the involvement of lymphocyte (Ly) in the setting of the congestive heart failure (CHF) are few. To address this issue, we investigated the function of Ly obtained from cervical lymph nodes from post-MI CHF rats submitted to treadmill running training. Methods: Twenty-five male Wistar rats were randomly assigned to the following groups: rats submitted to ligation of the left coronary artery, which were sedentary (MI-S, N= 7, only limited activity) or trained (MI-T, N= 6, on a treadmill (0% grade at 13-20 m.m(-1)) for 60 min.d(-1), 5 d.wk(-1), for 8-10 wk); or sham-operated rats, which were sedentary (sham-S, N = 6) or trained (sham-T, N = 6). The incorporation of [2-C-14]-thymidine by Ly cultivated in the presence of concanavalin A (Con A) and lipopolysaccharide (LPS), cytokine production by Ly cultivated in the presence of phytohemagglutinin (PHA), and plasma concentration of glutamine were assessed in all groups, 48 h after the last exercise session. Results: Proliferative capacity was increased, following incubation with Con-A in the MI groups, when compared with the sham counterparts. When incubated in the presence of PHA, MI-S produced more IL-4 (96%) than sham-S (P < 0.001). The training protocol induced a 2.2-fold increase in the production of interleukin-2 (P < 0.001) of the cells obtained from the cervical lymph nodes of MI-T, compared with MI-S. Conclusion: The moderate endurance training protocol caused an increase in IL-2 production, and a trend toward the reversion of the Th-1/Th-2 imbalance associated with IL-4 production increased in the post-MI CHF animal model.
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Visando conhecer a relação parasito hospedeiro de M. enterolobii em plantas com resistência a nematoides das galhas, estudos comparativos da biologia de M. enterolobii e M. javanica em tomateiros com o gene Mi foram conduzidos. O experimento foi conduzido em esquema fatorial 2x2, composto de dois porta-enxertos de tomateiro ('Magnet' e 'Helper M') e duas espécies de nematoides das galhas (M. enterolobii e M. javanica) com cinco repetições. As plantas foram inoculadas com 500 juvenis infectantes (J2) de M. enterolobii ou M. javanica. As raízes foram coletadas aos 3, 10, 17, 24 e 31 dias após a inoculação, coloridas com fucsina ácida, e dissecadas sob microscópio estereoscópico para a localização e contagem dos diferentes estádios de desenvolvimento dos nematoides. Os dados foram submetidos à análise de variância e as médias comparadas pelo teste de Tukey a 5% de probabilidade. Os resultados obtidos mostraram que, embora ambas as espécies tenham sido capazes de penetrar as raízes dos porta-enxertos de tomateiro, somente M. enterolobii conseguiu desenvolver-se normalmente, com as fêmeas maduras realizando suas posturas, a partir de 24 dias após a inoculação.
Treatment of tumor cells with low concentration of 5-Fu hinders the sensitization of dendritic cells
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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A greenhouse experiment was conducted in the Soil Science Department of the Botucatu College of Agricultural Sciences (UNESP), Brazil, using a Dark Red Latosol in 25 L pots. The soil was limed to 50 and 70% of base saturation; and doses 0, 10, 20, 30 and 40 t ha-1 of chicken manure were applied, in December of 1999. The experimental design was completely randomized blocks with a factorial arrangement 5x2, 10 treatments and three replications. This work was carried to evaluate leaf number, height plants, fresh and dry weight by aerial part of sweet fennel, and macronutrients and micronutrients removal. The organic fertilization affected the accumulation of N, P, K, S, B and Mn; liming affected the nutrient uptake, except for the Ca, Mg, S and Fe; the interaction of factors affected K, Mg and Mn.
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• Aim: To observe the effects of topical application of 5-fluorouracil (5-FU) on the rabbits corneal limbus. • Methods: 5-FU was applied topically to the corneoscleral region of rabbits eyes. The animals were sacrificed immediately or 7, 15, 30 and 60 days later, and tissues were submitted to histological examination. • Results: All animals presented corneoscleral deepithelization close to the site of application during the immediate post-operative period, whereas on the 4th postoperative day ulceration was no longer present. Histological examination showed absence of epithelium and slight edema. After one week (G2), 2 animals presented epithelial defects, thickened epithelium with larger basal cells and loose chromatin, and slight subepithelial edema. The remaining groups showed no alterations. • Conclusion: The 5-FU topically on the corneoscleral limbus postpone the epitelization.
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La recopilación incluye materiales existentes tanto en la Biblioteca CEPAL/ILPES como en otras bibliotecas de Santiago y Argentina, así como también en la Sección Archivos de CEPAL.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)