The Carlyle collection. A catalogue of books on Oliver Cromwell and Frederick the Great, bequeathed by Thomas Carlyle to Harvard College Library.

Oliver Cromwell. A cast from the original mask taken after death ..." (plate facing p. [2])

Australasian bibliography.... Catalogue of books in the Free Public Library, Sydney, relating to, or published in Australasia... Reference Library. 1869-1888.

"Class M.E. Periodical and serial literature, 1869-88", part 3, p. 109-133.

The life of St. Cuthbert in English verse, c. A.D. 1450. From the original ms. in the library at Castle Howard.

Includes indexes.

A catalog of the books belonging to the Charleston library society.

Bound with this copy are: "A supplemental catalogue ... of all the books ... procured by the Charleston library society, since the publication of the first volume of their catalogue in 1826", Charleston, 1831; and the "Catalogue of the library of the South Carolina college ... 1836."

Annual Report of the Trustees [and the Librarian] of the State Library

Continues the Reports of the Librarian

Report of the Librarian of Congress and Report of the Superintendent of the Library Building and Grounds for the fiscal year ending June 30 ...

Mode of access: Internet.

Library bulletin of Cornell University

Nos. 1-12 issued under title: The Library of Cornell University

[Hearings, reports and prints of the Joint Committee on the Library].

Mode of access: Internet.

A catalogue of the law library at Hartwell House, Buckinghamshire /

On spine: Hartwell law catalogue.

The future of the public library:reimagining the moral economy of the 'people's university'

New media technologies, the digitisation of information, learning archives and heritage resources are changing the nature of the public library and museums services across the globe, and, in so doing, changing the way present and future users of these services interact with these institutions in real and virtual spaces. New digital technologies are rewriting the nature of participation, learning and engagement with the public library, and fashioning a new paradigm where virtual and physical spaces and educative and temporal environments operate symbiotically. It is with such a creatively disruptive paradigm that the £193 million Library of Birmingham project in the United Kingdom is being developed. New and old media forms and platforms are helping to fashion new public places and spaces that reaffirm the importance of public libraries as conceived in the nineteenth century. As people’s universities, the public library service offers a web of connective learning opportunities and affordances. This article considers the importance of community libraries as sites of intercultural understanding and practical social democracy. Their significance is reaffirmed through the initial findings in the first of a series of community interventions forming part of a long-term project, ‘Connecting Spaces and Places’, funded by the Royal Society of Arts.

Manuscript Digitization and Electronic Processing of Manuscripts in the Czech National Library

The paper informs about the history of manuscript digitization in the National Library of the Czech Republic as well as about other issues concerning processing of manuscripts. The main consequence of the massive digitization and record and/or full text processing is a paradigm shift leading to the digital history.

Cataloguing the Slavonic Manuscript Collection of the Plovdiv Public Library – Problems and MARC 21* Solutions

MARC 21 (‘Machine-Readable Cataloguing’) is a US library standard established worldwide and recently translated also in Bulgarian (those parts used most by librarians in their everyday work). The Bulgarian translations are freely available on the NALIS website (http://www.nalis.bg/) under the Library Standards Section, where also an Online Multilingual Dictionary of MARC 21 Terms can be found. All these works are approved by the US Library of Congress and published on its MARC 21 website under Translations (http://www.loc.gov/marc/translations.html#bulgarian).

Isolation and Validation of Anti-B7-H4 scFvs from an Ovarian Cancer scFv Yeast-Display Library.

B7-H4 (VTCN1, B7x, B7s) is an inhibitory modulator of T-cell response implicated in antigen tolerization. As such, B7-H4 is an immune checkpoint of potential therapeutic interest. To generate anti-B7-H4 targeting reagents, we isolated antibodies by differential cell screening of a yeast-display library of recombinant antibodies (scFvs) derived from ovarian cancer patients and we screened for functional scFvs capable to interfere with B7-H4-mediated inhibition of antitumor responses. We found one antibody binding to B7-H4 that could restore antitumor T cell responses. This chapter gives an overview of the methods we developed to isolate a functional anti-B7-H4 antibody fragment.

Novel Anti-Campylobacter Compounds Identified Using High Throughput Screening of a Pre-selected Enriched Small Molecules Library

Campylobacter is a leading cause of foodborne bacterial gastroenteritis worldwide and infections can be fatal. The emergence of antibiotic-resistant Campylobacter spp. necessitates the development of new antimicrobials. We identified novel anti-Campylobacter small molecule inhibitors using a high throughput growth inhibition assay. To expedite screening, we made use of a “bioactive” library of 4,182 compounds that we have previously shown to be active against diverse microbes. Screening for growth inhibition of Campylobacter jejuni, identified 781 compounds that were either bactericidal or bacteriostatic at a concentration of 200 µM. Seventy nine of the bactericidal compounds were prioritized for secondary screening based on their physico-chemical properties. Based on the minimum inhibitory concentration against a diverse range of C. jejuni and a lack of effect on gut microbes, we selected 12 compounds. No resistance was observed to any of these 12 lead compounds when C. jejuni was cultured with lethal or sub-lethal concentrations suggesting that C. jejuni is less likely to develop resistance to these compounds. Top 12 compounds also possessed low cytotoxicity to human intestinal epithelial cells (Caco-2 cells) and no hemolytic activity against sheep red blood cells. Next, these 12 compounds were evaluated for ability to clear C. jejuni in vitro. A total of 10 compounds had an anti-C. jejuni effect in Caco-2 cells with some effective even at 25 µM concentrations. These novel 12 compounds belong to five established antimicrobial chemical classes; piperazines, aryl amines, piperidines, sulfonamide and pyridazinone. Exploitation of analogues of these chemical classes may provide Campylobacter specific drugs that can be applied in both human and animal medicine.

New Instruments for Impact Assessment: study of an academic library

This study presents a review of new instruments for the impact assessment of libraries and a case study of the evaluation impact of the Library of the Faculty of Science, University of Porto (FCUP), from the students’ point of view. We con ducted a mixed methods research, i.e., which includes both qualitative data, to describe characteristics, in particular human actions, and quantitative data, represented by numbers that indicate exact amounts which can be statistically manipulated. Applying International Standard ISO16439:2014 (E) - Information and documentation - Methods and procedures for assessing the impact of libraries, we collected, 20 opinion texts from students of different nationalities, published in «Notícias da Biblioteca», from January 2013 to December 2014 and have conducted seven interviews.