978 resultados para 860[82]-2.09


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The preparation of nanostructured materials using natural clays as support, has been studied in literature under the same are found in nature and consequently, have a low price. Generally, clays serve as supports for metal oxides by increasing the number of active sites present on the surface and can be applied for various purposes such as adsorption, catalysis and photocatalysis. Some of the materials that are currently highlighted are niobium compounds, in particular, its oxides, by its characteristics such as high acidity, rigidity, water insolubility, oxidative and photocatalytic properties. In this scenario, the study aimed preparing a composite material oxyhydroxide niobium (NbO2OH) / sodium vermiculite clay and evaluate its effectiveness with respect to the natural clay (V0) and NbO2OH. The composite was prepared by precipitation-deposition method and then characterized by X-ray diffraction, infrared spectroscopy (XRD), energy dispersive X-ray (EDS), thermal analysis (TG/DTG), scanning electron microscopy (SEM), N2 adsorption-desorption and investigation of distribution of load. The application of the material NbO2OH/V0 was divided in two steps: first through oxidation and adsorption methods, and second through photocatalytic activity using solar irradiation. Studies of adsorption, oxidation and photocatalytic oxidation monitored the percentage of color removal from the dye methylene blue (MB) by UV-Vis spectroscopy. The XRD showed a decrease in reflection d (001) clay after modification; the FTIR indicated the presence of both the clay when the oxyhydroxide niobium to present bands in 1003 cm-1 related to Si-O stretching bands and 800 cm-1 to the Nb-O stretching. The presence of niobium was also confirmed by EDS indicated that 17 % by mass amount of the metal. Thermal analysis showed thermal stability of the composite at 217 °C and micrographs showed that there was a decrease in particle size. The investigation of the surface charge of NbO2OH/V0 found that the material exhibits a heterogeneous surface with average low and high negative charges. Adsorption tests showed that the composite NbO2OH/V0 higher adsorption capacity to remove 56 % of AM, while the material removed from V0 only 13 % showed no NbO2OH and adsorptive capacity due to the formation of H-aggregates. The percent removal of dye color for the oxidation tests showed little difference from the adsorption, being 18 and 66 % removal of dye color for V0 and NbO2OH/V0 respectively. The NbO2OH/V0 material shows excellent photocatalytic activity managing to remove just 95,5 % in 180 minutes of the color of MB compared to 41,4 % and 82,2 % of V0 the NbO2OH, proving the formation of a new composite with distinct properties of its precursors.

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The Late Quaternary sediment sequence of the continental margin in the eastern Weddell Sea is well suited for palaeoenvironmental reconstructions. Two cores from the upper slope, which contain the sedimentary record of the last 300 ky, have been sedimentologically investigated. Age models are based on lithostratigraphy and are correlated with the stable isotope record. As a result of a detailed analysis of the clay mineral composition, grain size distributions and structures, this sedimentary record provides the first marine evidence that the Antarctic ice sheet extended to the shelf edge during the last glacial. The variations in volume and size of the ice sheet were also simulated in numerical models. Changes in accumulation rate and ice temperature are of some importance, but the model revealed that fluctuations are primarily driven by changes in eustatic sea-level and that the ice edge extended to the shelf edge during the last glacial maximum. This causal relationship implies that the maximum ice extension strongly depends on the magnitude and duration of the sea-level depression during a glacial period. The results of the sedimentological investigations and of the numerical models show that the Antarctic ice sheet follows glacial events in the northern hemisphere by teleconnections of sea level.

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Ocean acidification will likely have negative impacts on invertebrates producing skeletons composed of calcium carbonate. Skeletal solubility is partly controlled by the incorporation of "foreign" ions (e.g. magnesium) into the crystal lattice of these skeletal structures, a process that is sensitive to a variety of biological and environmental factors. Here we explore effects of life stage, oceanographic region of origin, and changes in the partial pressure of carbon dioxide in seawater (pCO2) on trace elemental composition in the purple sea urchin (Strongylocentrotus purpuratus). We show that, similar to other urchin taxa, adult purple sea urchins have the ability to precipitate skeleton composed of a range of biominerals spanning low- to high-Mg calcites. Mg / Ca and Sr / Ca ratios were substantially lower in adult spines compared to adult tests. On the other hand, trace elemental composition was invariant among adults collected from four oceanographically distinct regions spanning a range of carbonate chemistry conditions (Oregon, Northern California, Central California, and Southern California). Skeletons of newly settled juvenile urchins that originated from adults from the four regions exhibited intermediate Mg / Ca and Sr / Ca between adult spine and test endmembers, indicating that skeleton precipitated during early life stages is more soluble than adult spines and less soluble than adult tests. Mean skeletal Mg / Ca or Sr / Ca of juvenile skeleton did not vary with source region when larvae were reared under present-day, global-average seawater carbonate conditions (400 µatm; pHT = 8.02 ± 0.03 1 SD; Omega calcite = 3.3 ± 0.2 1 SD). However, when reared under elevated pCO2 (900 µatm; pHT = 7.73 ± 0.03; Omega calcite = 1.8 ± 0.1), skeletal Sr / Ca in juveniles exhibited increased variance across the four regions. Although larvae from the northern populations (Oregon, Northern California, Central California) did not exhibit differences in Mg or Sr incorporation under elevated pCO2 (Sr / Ca = 2.10 ± 0.06 mmol/mol; Mg / Ca = 67.4 ± 3.9 mmol/mol), juveniles of Southern California origin partitioned ~8% more Sr into their skeletons when exposed to higher pCO2 (Sr / Ca = 2.26 ± 0.08 vs. 2.09 ± 0.005 mmol/mol 1 SD). Together these results suggest that the diversity of carbonate minerologies present across different skeletal structures and life stages in purple sea urchins does not translate into an equivalent geochemical plasticity of response associated with geographic variation or temporal shifts in seawater properties. Rather, composition of S. purpuratus skeleton precipitated during both early and adult life history stages appears relatively robust to spatial gradients and predicted future changes in carbonate chemistry. An exception to this trend may arise during early life stages, where certain populations of purple sea urchins may alter skeletal mineral precipitation rates and composition beyond a given pCO2 threshold. This potential for geochemical plasticity during early development in contrast to adult stage geochemical resilience adds to the growing body of evidence that ocean acidification can have differing effects across organismal life stages.

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Tourmaline from a gem-quality deposit in the Grenville province has been studied with X-ray diffraction, visible-near infrared spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy, electron microprobe and optical measurements. The tourmaline is found within tremolite-rich calc-silicate pods hosted in marble of the Central Metasedimentary Belt. The crystals are greenish-greyish-brown and have yielded facetable material up to 2.09 carats in size. Using the classification of Henry et al. 2011 the tourmaline is classified as a dravite, with a representative formula shown to be (Na0.73Ca0.2380.032)(Mg2+2.913Fe2+0.057Ti4+0.030) (Al3+5.787Fe3+0.017Mg2+0.14)(Si6.013O18)(BO3)3(OH)3((OH,O)0.907F0.093). Rietveld analysis of powder diffraction data gives a = 15.9436(8) Å, c = 7.2126(7) Å and a unit cell volume of 1587.8 Å3. A polished thin section was cut perpendicular to the c-axis of one tourmaline crystal, which showed zoning from a dark brown core into a lighter rim into a thin darker rim and back into lighter zonation. Through the geochemical data, three key stages of crystal growth can be seen within this thin section. The first is the core stage which occurs from the dark core to the first colourless zone; the second is from this colourless zone increasing in brown colour to the outer limit before a sudden absence of colour is noted; the third is a sharp change from the end of the second and is entirely colourless. These events are the result of metamorphism and hydrothermal fluids resulting from nearby felsic intrusive plutons. Scanning electron microscope, and electron microprobe traverses across this cross-section revealed that the green colour is the result of iron present throughout the system while the brown colour is correlated with titanium content. Crystal inclusions in the tourmaline of chlorapatite, and zircon were identified by petrographic analysis and confirmed using scanning electron microscope data and occur within the third stage of formation.

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Morphological, anatomical and physiological plant and leaf traits of A. distorta, an endemic species of the Central Apennines on the Majella Massif, growing at 2,675 m a.s.l, were analyzed. The length of the phenological cycle starts immediately after the snowmelt at the end of May, lasting 128 ± 10 days. The low A. distorta height  (Hmax= 64 ± 4 mm) and total leaf area (TLA= 38 ± 9 cm2) associated to a high leaf mass area (LMA =11.8±0.6 mg cm−2) and a relatively high leaf tissue density (LTD = 124.6±14.3 mg cm−3) seem to be adaptive traits to the stress factors of the environment where it grows. From a physiological point of view, the high A. distorta photosynthetic rates (PN =19.6 ± 2.3 µmol m−2 s−1) and total chlorophyll content (Chla+b = 0.88 ± 0.13 mg g−1) in July are justified by the favorable temperature. PN decreases by 87% in September at the beginning of plant senescence. Photosynthesis and leaf respiration (RD) variations allow A. distorta to maintain a positive carbon balance during the growing season becoming indicative of the efficiency of plant carbon use. The results could be an important tool for conservation programmes of the A. distorta wild populations.

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Introdução: Muitos estudos sobre o envelhecimento, mais especificamente, sobre o declínio cognitivo, enfatizam que uma das funções mentais prejudicadas é a atenção. Também tem sido apontada uma clara associação entre o declínio e a ansiedade e os sintomas de depressão. A associação entre declínio e as variáveis demográficas tem sido encontrada, em particular, uma correlação significativa com a idade. Pretendemos explorar as associações entre a atenção seletiva avaliada pelo Teste de Stroop (Stroop Respostas Corretas_ Leitura, Stroop Respostas Corretas_Cor, Diferença entre Stroop Respostas Corretas_Leitura e Stroop Repostas Corretas_Cor, Stroop Rácio Leitura: divisão das respostas corretas pelo tempo; Stroop Rácio Cor: divisão das respostas corretas pelo tempo e Diferença entre Stroop Rácio Leitura e Stroop Rácio Cor) e o declínio cognitivo avaliado pelo MoCA (como uma variável estratificada por idade e escolaridade e dicotomizada, e como variável contínua), numa amostra de idosos institucionalizados. No caso de obtermos resultados significativos pretende-se verificar o valor preditivo dos resultados obtidos com o teste Stroop (seis variáveis) para o declínio cognitivo (MoCA dicotomizado: ausência/presença de declínio cognitivo), controlando a ansiedade e os sintomas de depressão e as variáveis sociodemográficas, caso encontremos associações significativas entre estas variáveis e declínio cognitivo. Metodologia: A amostra incluiu 140 idosos (média de idades, M = 78,4; Desvio-padrão, DP = 7,48; variação = 60 - 97) sob resposta social em instituições do Distrito de Coimbra que aceitaram responder voluntariamente ou cujos cuidadores concederam o consentimento a uma bateria de testes (incluindo questões sociodemográficas, o MoCA, o Geriatric Anxiety Inventory/GAI, a Geriatric Depression Scale/GDS e o teste de Stroop). Resultados: Da nossa amostra, 52 idosos (37, 1%) apresentam declínio cognitivo versus 88 (62, 9%) que não o apresentam. No que diz respeito às seis variáveis Stroop, o Stroop Respostas Corretas_Leitura apresentou uma média/M = 82, 2 (DP = 32, 47), o Stroop Respostas Corretas_Cor uma M de = 31, 2 (DP = 27, 88), a Diferença entre Stroop Respostas Corretas_Leitura e Stroop Repostas Corretas_Cor uma M de = 50, 34 (DP = 31, 60), o Stroop Rácio_Leitura uma M de = 0, 69 (DP = 0, 27) e o Stroop Rácio_Cor uma M de 0, 26 (DP = 0, 23), a diferença entre Stroop Rácio_Leitura e Stroop Rácio_Cor uma M de = 0, 43 (DP = 0, 26). O MoCA dicotomizado encontrou-se associado ao Stroop Respostas Corretas_Leitura, Stroop Respostas Corretas_Cor, Stroop Rácio_Leitura e Stroop Rácio_Cor. Mostrou-se, também, associado ao GDS e revelou uma associação estatisticamente significativa com a variável sociodemográfica escolaridade×profissão. A idade e escolaridade não foram testadas, uma vez que estratificámos a variável MoCA de acordo com a idade e a escolaridade. O GDS, o Stroop Rácio_Leitura e o Stroop Rácio_Cor mostraram-se preditoras de declínio cognitivo, na regressão logística realizada. Conclusão/Discussão: Mesmo que apenas transversalmente, os resultados confirmam a literatura, uma vez que se verificou associação entre Stroop Respostas Corretas_Leitura, o Stroop Respostas Corretas_Cor, o Stroop Rácio_Leitura e o Stroop Rácio_Cor e o declínio cognitivo, ou seja, confirmou-se que a atenção seletiva é menor quando o idoso revela declínio cognitivo. Embora não se tenha verificado associação entre o MoCA dicotomizado e as diferenças calculadas entre as Respostas Corretas (Stroop Respostas Corretas_Leitura e Stroop Respostas Corretas_Cor) e os Rácios (Stroop Rácio_Leitura e Stroop Rácio_Cor), corroborámos a associação com o GDS. As análises preditivas confirmaram o papel preditivo da atenção seletiva e da sintomatologia depressiva para a presença de declínio cognitivo. Será relevante intervir junto da população idosa, através de reabilitação cognitiva, para melhorar a sua habilidade atencional (atenção seletiva) e, assim, eventualmente reduzir a sintomatologia depressiva e ansiosa e retardar o declínio cognitivo.

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Despite elevated incidence and recurrence rates for Primary Spontaneous Pneumothorax (PSP), little is known about its etiology, and the genetics of idiopathic PSP remains unexplored. To identify genetic variants contributing to sporadic PSP risk, we conducted the first PSP genome-wide association study. Two replicate pools of 92 Portuguese PSP cases and of 129 age- and sex-matched controls were allelotyped in triplicate on the Affymetrix Human SNP Array 6.0 arrays. Markers passing quality control were ranked by relative allele score difference between cases and controls (|RASdiff|), by a novel cluster method and by a combined Z-test. 101 single nucleotide polymorphisms (SNPs) were selected using these three approaches for technical validation by individual genotyping in the discovery dataset. 87 out of 94 successfully tested SNPs were nominally associated in the discovery dataset. Replication of the 87 technically validated SNPs was then carried out in an independent replication dataset of 100 Portuguese cases and 425 controls. The intergenic rs4733649 SNP in chromosome 8 (between LINC00824 and LINC00977) was associated with PSP in the discovery (P = 4.07E-03, ORC[95% CI] = 1.88[1.22-2.89]), replication (P = 1.50E-02, ORC[95% CI] = 1.50[1.08-2.09]) and combined datasets (P = 8.61E-05, ORC[95% CI] = 1.65[1.29-2.13]). This study identified for the first time one genetic risk factor for sporadic PSP, but future studies are warranted to further confirm this finding in other populations and uncover its functional role in PSP pathogenesis.

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Le présent mémoire expose les résultats d’une étude de la performance des chantiers ouverts dans un contexte de mines profondes ayant été effectuée dans le cadre du projet de recherche « Mines profondes : défis d’exploitation et impacts sur la récupération minéralurgique » réalisé par le département de génie des mines, de la métallurgie et des matériaux de l’Université Laval. Les données utilisées dans le cadre de cette étude sont en lien avec la planification et l’exploitation de plus de mille chantiers minés entre 860 et 2 450 m de profondeur à la mine souterraine LaRonde de Mines Agnico Eagle, la plus profonde actuellement de l’hémisphère ouest. On y présente une revue de la littérature qui fait la description des problématiques de dilution et de pertes opérationnelles de la réserve minérale liées à la performance des chantiers ouverts ainsi que de leurs conséquences sur les projets miniers. Une comparaison des performances planifiées et réalisées au site de LaRonde y est présentée, ainsi que les résultats d’analyses statistiques ayant permis de montrer que la variation du ratio des contraintes in situ avec la profondeur est un facteur d’influence significatif de la performance des chantiers. L’effet de ce facteur d’influence y est aussi illustré et validé à l’aide d’une série de modèles numériques. Le mémoire présente également une première approche visant à développer un modèle d’évaluation de la dilution dans les chantiers ouverts qui prend en compte la profondeur de minage. Finalement, afin d’améliorer la précision de l’estimation de la réserve minérale lors de l’évaluation de projets miniers, une méthodologie d’estimation intégrant le modèle d’évaluation proposé est présentée pour les projets dont les contextes géologique, géotechnique et opérationnel sont comparables à ceux du site de LaRonde.

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Introduction. Total mesorectal excision (TME) is the cornerstone of a correct surgical therapy for extraperitoneal rectal cancer. Aim of the study is to evaluate our 5 years experience confronting retrospectively laparoscopic (lap) TME in respect to its laparotomic (open) counterpart. Patients and Methods. 30 patients were treated laparoscopically for stage I-III extraperitoneal rectal cancer and retrospectively compared to a homogeneous group, stratified for sex, age, comorbidities and stage of disease. Results. 30 days mortality was zero for both groups, while morbidity was 20% for the lap group and 36.6% for the open group. Mean lymph nodes harvested was 24 ± 12 for the lap group, 26 ± 14 for the open group (p > 0.05). Five years overall and disease free survival was respectively 82.2% and 81.4% in the lap group, 79.9% and 79.6% in the open group, without statistical significance (p>0.05). Discussion. Minimally invasive TME resulted a safe, effective and oncologically adequate procedure when retrospectively compared to its laparotomic counterpart, with 5 years overall survival and disease free survival reaching no statistical significance compared to the open approach, but with all the advantages of the laparoscopy such as less pain and blood loss, faster recovery, less morbidity and better cosmetics. Conclusions. Our study has retrospectively demonstrated that laparoscopic TME is feasible and oncologically effective, even if it remains a complex minimally invasive procedure, requiring adequate skill. More prospective, randomized studies are necessary to define such a procedure as the new gold standard in treatment of stage I-III extraperitoneal rectal cancer.

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Clinical utility of prokinetics in capsule endoscopy (CE) is not clearly established. The objective of this prospective, randomized, single-blind, controlled trial was to determine if metoclopramide is useful in CE by increasing the rate of complete enteroscopy. Ninety-five patients referred for CE were randomized to no metoclopramide (group B, n = 48) or 10 mg metoclopramide (group A, n = 47). Complete enteroscopy was possible in 38 patients of group A (80.9%) and 37 of group B (77.1%) (P = 0.422) with two cases of gastric retention in group B (4.2%; P = 0.253). Median gastric transit time was 26 min (1-211) in group A and 28 min (4-200) in group B (P = 0.511). Mean small bowel transit time, calculated after excluding 20 patients with incomplete enteroscopy, was similar in both groups (221.2 +/- 89 min vs. 256 +/- 82.2 min; P = 0.083). There were also no differences in the total number of findings (group A 4.5 +/- 4.7; group B 4.7 +/- 3.7, P = 0.815). Administration of 10 mg metoclopramide orally 15 min before capsule ingestion did not significantly increase the rate of total enteroscopies and had no effect on transit times. It also did not modify CE diagnostic yield.

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El estudio tiene el objetivo de determinar la prevalencia de Helicobacter Pylori y factores de riesgo asociados en niños en edad escolar del área urbana del cantón Cuenca. Resultados: la prevalencia de Helicobacter Pylori en escolares del área urbana del cantón Cuenca fue de 14.3: los factores de riesgo asociados a la infección que reflejaron significancia estadística fueron edad RP 1.79. (IC 1.10-2.87, P o.41); anafalbetismo de los padres RP 2.49, (ICI. 23-5. 03. P 0.017); no practicar el lavado de manos RP 63.40, (IC 15.71-255.84, P 0.000); no lavar los alimentos RP 9.88, (IC 5,43-17.97, P 0.000); compartir la cama RP 2.23, (IC 1,33-3.73, P 0.00); no disponer de servicio higiénico RP 5.11, (IC 3.01-8.66, P 0.000) y no consumir agua potable RP 4.79, (IC 2.96-7.74, P 0.000). También se encontró asociación con dolor abdominal recurrente RP 3.48, (IC 2.03-5.96, P 0.0000) Los factores de riesgo que no se asociaron a infección fueron género RP 1.36, (IC 0.82-2.24, P 0.224) y ocupación manual de los padres RP 1.21, (IC 0.54-2.68, P 0.626). Los signos y síntomas que no estuvieron asociados con la presencia de Helicobacter Pylori fueron naúsea y vómito RP 0.87, (IC 0.13-5.56, P 0.886); sensación de llenura RP 1.70, (IC 0.87-3.30, P 0.127) y pirosis RP 2.24, (IC 0.95-5.27, P 0.083). Conclusiones: 1. La prevalencia de Helicobacter Pylori en escolares del área urbana del cantón Cuenca 2003-2004 fue 14.3. 2. La prevalencia de Helicobacter Pylori es directamente proporcional con la edad. 3. La falta de aplicación de las normas básicas de higiene incrementa el riesgo de infección. 4. Las condiciones sanitarias desfavorables son un determinante para la mayor prevalencia de infección. 5. En la mayoría de escolares, la infección no cursó con sintomatología clínica. 6. Dolor abdominal recurrente fue la manifestación clínica más importante en niños sintomáticos infectados

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Despite elevated incidence and recurrence rates for Primary Spontaneous Pneumothorax (PSP), little is known about its etiology, and the genetics of idiopathic PSP remains unexplored. To identify genetic variants contributing to sporadic PSP risk, we conducted the first PSP genome-wide association study. Two replicate pools of 92 Portuguese PSP cases and of 129 age- and sex-matched controls were allelotyped in triplicate on the Affymetrix Human SNP Array 6.0 arrays. Markers passing quality control were ranked by relative allele score difference between cases and controls (|RASdiff|), by a novel cluster method and by a combined Z-test. 101 single nucleotide polymorphisms (SNPs) were selected using these three approaches for technical validation by individual genotyping in the discovery dataset. 87 out of 94 successfully tested SNPs were nominally associated in the discovery dataset. Replication of the 87 technically validated SNPs was then carried out in an independent replication dataset of 100 Portuguese cases and 425 controls. The intergenic rs4733649 SNP in chromosome 8 (between LINC00824 and LINC00977) was associated with PSP in the discovery (P = 4.07E-03, ORC[95% CI] = 1.88[1.22-2.89]), replication (P = 1.50E-02, ORC[95% CI] = 1.50[1.08-2.09]) and combined datasets (P = 8.61E-05, ORC[95% CI] = 1.65[1.29-2.13]). This study identified for the first time one genetic risk factor for sporadic PSP, but future studies are warranted to further confirm this finding in other populations and uncover its functional role in PSP pathogenesis.

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Justificación: La osteoporosis es causa de fracturas patológicas y pérdida de autonomía y validismo en la mujer post-menopáusica. La identificación de factores de riesgo puede servir en la prevención de la aparición de esta co-morbilidad. Objetivos: Determinar la asociación entre la desmineralización ósea y características demográficas, clínicas y antropométricas selectas de la mujer post-menopásica que puedan asumirse como factores de riesgo. Diseño del estudio: No experimental, transversal, analítico. Serie de estudio: 53 mujeres con edades ≥ 60 años atendidas en el Hospital "San Juan" de Especialidades de Riobamba (Provincia del Chimborazo, República del Ecuador). Material y método: Se determinó la densidad mineral ósea (DMO) en 2 regiones de interés (columna lumbar I fémur) mediante DEXA (DPX-L, Lunar Technologies, EEUU). La desmineralización ósea se estableció ante puntajes "t" < -1,0 desviaciones estándar. La cuantía y calidad de los ingresos de Calcio dietético se estimaron mediante el puntaje pCa que tiene en cuenta la frecuencia de consumo de alimentos tenidos como fuente de calcio y la biodisponibilidad del mineral. Se evaluaron la naturaleza y la fuerza de la asociación entre la desmineralización ósea, por un lado, y los factores presuntivos de riesgo de osteoporosis y el estado del ingreso del calcio dietético, por el otro. Resultados: La desmineralización ósea fue dependiente de la región de interés: Fémur: Osteoporosis: 13,2% + Osteopenia: 50,9%; Columna lumbar: Osteoporosis: 49,1% + Osteopenia: 37,7%. Los mayores ingresos de calcio dietético se concentraron en: Leche y lácteos (pCa = 26,56), Carnes, pescados, mariscos y huevos (pCa = 6,51), Frijoles y otras leguminosas (soja incluida) (pCa = 2,85); y Verduras (pCa = 2,54); respectivamente. El puntaje "t" de DMO se asoció con la edad de la mujer, los antecedentes familiares de fracturas óseas, el Índice de Masa Corporal (IMC), y la grasa corporal (estimada mediante DEXA). Los ingresos de calcio dietético fueron independientes de los factores presuntivos de riesgo de desmineralización ósea, y del puntaje "t" de DMO en las regiones de interés. Las razones de disparidades para las variables asociadas univariadamente con la DMO fueron como sigue: Edad: OR = 2,09 (p < 0,05); IMC: OR = 0,278 (p = 0,059): y Grasa corporal: OR = 0,553 (p > 0,05); respectivamente. Conclusiones: La desmineralización ósea se asocia significativamente con el envejecimiento femenino, y una mayor presencia de la grasa corporal. Los antecedentes familiares de fracturas óseas pueden servir para identificar a la mujer post-menopáusica con un riesgo incrementado de desmineralización ósea. Se deben emprender investigaciones ulteriores para establecer el papel del ejercicio físico y mejores ingresos de calcio dietético como factores protectores de la pérdida de la DMO.