Implementation of Triple P-Positive Parenting Program in Hong Kong: Predictors of programme completion and clinical outcomes

This study examined the effectiveness of the Triple P-Positive Parenting Program in a government child health service delivery context with Chinese parents in Hong Kong. Specifically, the study sought to identify pre-intervention variables that might predict programme outcomes such as, level of clinical improvement and programme completion. Participants were 661 parents of pre-school and primary aged children participating in a group version of the Triple P-Positive Parenting Program. There were significant decreases in disruptive child behaviours, levels of parenting stress, general stress and anxiety and an increase in parenting sense of competence. Greater change in reports of child behaviour problems was related to lower levels of family income, new immigrant family status, and higher pre-intervention levels of parenting stress. The present study provides a profile of parents who are most likely to benefit from parent training programmes.

Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth

One classical feature of cancer cells is their metabolic acquisition of a highly glycolytic phenotype. Carbon monoxide (CO), one of the products of the cytoprotective molecule heme oxygenase-1 (HO-1) in cancer cells, has been implicated in carcinogenesis and therapeutic resistance. However, the functional contributions of CO and HO-1 to these processes are poorly defined. In human prostate cancers, we found that HO-1 was nuclear localized in malignant cells, with low enzymatic activity in moderately differentiated tumors correlating with relatively worse clinical outcomes. Exposure to CO sensitized prostate cancer cells but not normal cells to chemotherapy, with growth arrest and apoptosis induced in vivo in part throughmitotic catastrophe. CO targeted mitochondria activity in cancer cells as evidenced by higher oxygen consumption, free radical generation, and mitochondrial collapse. Collectively, our findings indicated that CO transiently induces an anti-Warburg effect by rapidly fueling cancer cell bioenergetics, ultimately resulting in metabolic exhaustion. ©2013 AACR.

Performance of FRP-concrete bridges under blast loading

Catastrophic failure from intentional terrorist attacks on surface transportation infrastructure could he detrimental to the society. In order to minimize the vulnerabilities and to ensure a safe transportation system, the issue of security for transportation structures, primarily bridges, which are subjected to man-made hazards is investigated in this study. A procedure for identifying and prioritizing "critical bridges" using a screening and prioritization processes is established. For each of the "critical" bridges, a systematic risk-based assessment approach is proposed that takes into account the combination of threat occurrence likelihood, its consequences, and the socioeconomic importance of the bridge. A series of effective security countermeasures are compiled in the four categories of deterrence, detection, defense and mitigation to help reduce the vulnerability of critical bridges. The concepts of simplified equivalent I-shape cross section and virtual materials are proposed for integration into a nonlinear finite element model, which helps assess the performance of reinforced concrete structures with and without composite retrofit or hardening measures under blast loading. A series of parametric studies are conducted for single column and two-column pier frame systems as well as for an entire bridge. The parameters considered include column height, column type, concrete strength, longitudinal steel reinforcement ratio, thickness, fiber angle and tensile strength of the fiber reinforced polymer (FRP) tube, shape of the cross section, damping ratio and different bomb sizes. The study shows the benefits of hardening with composites against blast loading. The effect of steel reinforcement on blast resistance of the structure is more significant than the effect of concrete compressive strength. Moreover, multiple blasts do not necessarily lead to a more severe destruction than a single detonation at a strategically vulnerable location on the bridges.

Studio del modello Augmented Worlds per l'ingegneria di sistemi software basati su realtà aumentata: esplorazioni basate su Unity e Android

Negli ultimi anni il crescere della capacità di calcolo dei dispositivi e il diminuire delle loro dimensioni ha permesso di far nascere idee innovative e di esplorare più in dettaglio alcuni settori. Uno di questi è sicuramente quello della realtà aumentata (Augmented reality), infatti, la discussione su questo argomento nasce già negli anni 40 del novecento, ma, per mancanza di mezzi tecnologici adeguati, solo ora si iniziano a realizzare le prime applicazioni che si basano su questa idea e il grande pubblico inizia ad interessarsi all'argomento. La costruzione di applicazioni di realtà aumentata, al momento, è basata sull'utilizzo di alcuni framework che mettono a disposizione dello sviluppatore alcune funzioni molto comuni in questi software, come il tracking di marker e l'utilizzo di bottoni virtuali. Questi strumenti, seppur comodi, non garantiscono sempre la buona progettazione dell'applicazione e tendono a unire insieme parti di logica applicativa e di grafica. Per questo motivo, anche nella ricerca, si stanno cercando di studiare dei metodi in grado di permettere una divisione ottimale dei compiti in modo da ottenere un software riusabile e facilmente mantenibile, ma che permetta anche di sfruttare appieno le potenzialità dell'AR attraverso, per esempio, sistemi distribuiti. Un framework concettuale che rientra in questa categoria è sicuramente quello degli Augmented Worlds, mondi virtuali collegati a quello fisico che ne incrementano le caratteristiche e le possibilità tramite la presenza di entità aumentate. La tesi, quindi, si propone di sviluppare un prototipo di un framework con le caratteristiche sopra citate di estendibilità, utilizzando le piattaforme in questo momento a disposizione e ispirandosi alla visione degli Augmented Worlds.

Babybag: borsa seggiolino per bambino

La Babybag è una borsa leggera, facile da trasportare e utile con i bambini sia in casa che fuori casa. Non si tratta però di una semplice borsa portaoggetti. Sul lato esterno si trovano fogli bianchi e pennarelli che i bambini possono utilizzare per disegnare e colorare. Sbottonando il laccio frontale è invece possibile accedere al suo contenuto: un rivestimento per lo schienale che si trasforma in un seggiolino grazie a lacci regolabili e bottoni. Anche la parte esterna della borsa si trasforma essa stessa in un rivestimento per la parte inferiore della seduta.

Inventory of thermo-erosional valleys and streams in three ice-rich permafrost lowlands adjacent to the Laptev Sea, with links to maps in ArcGIS format

This dataset provides an inventory of thermo-erosional landforms and streams in three lowland areas underlain by ice-rich permafrost of the Yedoma-type Ice Complex at the Siberian Laptev Sea coast. It consists of two shapefiles per study region: one shapefile for the digitized thermo-erosional landforms and streams, one for the study area extent. Thermo-erosional landforms were manually digitized from topographic maps and satellite data as line features and subsequently analyzed in a Geographic Information System (GIS) using ArcGIS 10.0. The mapping included in particular thermo-erosional gullies and valleys as well as streams and rivers, since development of all of these features potentially involved thermo-erosional processes. For the Cape Mamontov Klyk site, data from Grosse et al. [2006], which had been digitized from 1:100000 topographic map sheets, were clipped to the Ice Complex extent of Cape Mamontov Klyk, which excludes the hill range in the southwest with outcropping bedrock and rocky slope debris, coastal barrens, and a large sandy floodplain area in the southeast. The mapped features (streams, intermittent streams) were then visually compared with panchromatic Landsat-7 ETM+ satellite data (4 August 2000, 15 m spatial resolution) and panchromatic Hexagon data (14 July 1975, 10 m spatial resolution). Smaller valleys and gullies not captured in the maps were subsequently digitized from the satellite data. The criterion for the mapping of linear features as thermo-erosional valleys and gullies was their clear incision into the surface with visible slopes. Thermo-erosional features of the Lena Delta site were mapped on the basis of a Landsat-7 ETM+ image mosaic (2000 and 2001, 30 m ground resolution) [Schneider et al., 2009] and a Hexagon satellite image mosaic (1975, 10 m ground resolution) [G. Grosse, unpublished data] of the Lena River Delta within the extent of the Lena Delta Ice Complex [Morgenstern et al., 2011]. For the Buor Khaya Peninsula, data from Arcos [2012], which had been digitized based on RapidEye satellite data (8 August 2010, 6.5 m ground resolution), were completed for smaller thermo-erosional features using the same RapidEye scene as a mapping basis. The spatial resolution, acquisition date, time of the day, and viewing geometry of the satellite data used may have influenced the identification of thermo-erosional landforms in the images. For Cape Mamontov Klyk and the Lena Delta, thermo-erosional features were digitized using both Hexagon and Landsat data; Hexagon provided higher resolution and Landsat provided the modern extent of features. Allowance of up to decameters was made for the lateral expansion of features between Hexagon and Landsat acquisitions (between 1975 and 2000).

Glycerol dialkyl glycerol tetraethers (GDGT) abundance of sediment core GeoB15103-1

Marine microorganisms adapt to their habitat by structural modification of their membrane lipids. This concept is the basis of numerous molecular proxies used for paleoenvironmental reconstruction. Archaeal tetraether lipids from ubiquitous marine planktonic archaea are particularly abundant, well preserved in the sedimentary record and utilized in several molecular proxies. We here introduce the direct, extraction-free analysis of these compounds in intact sediment core sections using laser desorption ionization (LDI) coupled to Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS). LDI FTICR-MS can detect the target lipids in single sub-mm sized spots on sediment sections, equivalent to a sample mass in the nanogram range, and could thus pave the way for biomarker-based reconstruction of past environments and ecosystems at subannual to decadal resolution. We demonstrate that ratios of selected archaeal tetraethers acquired by LDI FTICR-MS are highly correlated with values obtained by conventional LC/MS protocols. The ratio of the major archaeal lipids, caldarchaeol and crenarchaeol, analyzed in a 6.2-cm intact section of Mediterranean sapropel S1 at 250-µm resolution (~4-year temporal resolution), provides an unprecedented view of the fine-scale patchiness of sedimentary biomarker distributions and the processes involved in proxy signal formation. Temporal variations of this lipid ratio indicate a strong influence of the 200-yr de Vries solar cycle on reconstructed sea surface temperatures with possible amplitudes of several degrees, and suggest signal amplification by a complex interplay of ecological and hydrological factors. Laser-based biomarker analysis of geological samples has the potential to revolutionize molecular stratigraphic studies of paleoenvironments.

Location and ages of terrestrial peatlands located on continental shelves and in coastal sediments

This synthesis dataset contains records of freshwater peat and lake sediments from continental shelves and coastal areas. Information included is site location (when available), thickness and description of terrestrial sediments as well as underlying and overlying sediments, dates (when available), and references.

Permafrost longterm monitoring sites (Arctic and Antarctic)

About 50 locations ('cold spots') where permafrost (Arctic and Antarctic) in situ monitoring has been taking place for many years or where field stations are currently established (through, for example the Canadian ADAPT program) have been identified. These sites have been proposed to WMO Polar Space Task Group as focus areas for future monitoring by satellite data. Seven monitoring transects spanning different permafrost types have been proposed in addition.

Artisans, génies et vedettes : le statut des compositeurs dans la presse musicale française

Ce mémoire propose d’explorer quel(s) statut(s) sont accordés aux compositeurs contemporains dans le contexte musical parisien des premières années du XXe siècle à travers une analyse de la presse musicale spécialisée de l’époque. Le corpus de notre recherche est constitué de trois revues, chacune ancrée dans des sphères de sociabilités bien distinctes : La Revue musicale (histoire et critique), une « revue savante » proche du milieu de la Schola cantorum ; Le Mercure musical, une « petite revue » d’avant-garde militant en faveur de la musique de Maurice Ravel ; et Musica, une « grande revue » destinée à un lectorat issu de la petite bourgeoisie en plein essor, essentiellement féminin et pratiquant la musique en amateur. Cette étude révèle que la traditionnelle opposition entre la conception du compositeur-artisan et celle du compositeur-génie issue de la fin du XVIIIe siècle et du XIXe siècle voit apparaître un troisième joueur à l’aube du XXe siècle : le compositeur-vedette, un statut qui était jusqu’alors généralement réservé aux interprètes. Ces trois statuts coexistent dans le panorama de la presse musicale du tournant du XXe siècle, et leur promotion par certains organes de presse spécifiques répond à une logique tantôt esthétique, tantôt économique. Il se dégage de cette étude que la presse musicale constitue non seulement un indice des variations qu’a subies la figure du compositeur dans le spectre de la grandeur en culture, mais qu’elle a également joué un rôle actif dans ces transformations.

Effet d'un extrait plaquettaire sur l'expansion ex vivo de progéniteurs hématopoïétiques

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal.

Les théories postmodernes de la traduction

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

Effet d'un extrait plaquettaire sur l'expansion ex vivo de progéniteurs hématopoïétiques

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal.

Les théories postmodernes de la traduction

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.