Filogeografia e estrutura populacional de Astyanax paranae (Lambari-de-cabeceira) (Pisces: Characidae) na bacia do Rio Tietê

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China: uma análise dos fatores do crescimento econômico pós-abertura de 1978

A China têm se destacado entre os países emergentes desde sua abertura comercial, no ano de 1978, pelas altas taxas de crescimento econômico, o que permitiu que o país chegasse a segunda maior economia mundial em 2011. Apesar de ter tido um passado pautado, majoritariamente, na agricultura e no isolamento econômico, com um regime político comunista, no final da década de 1970, a China desenvolveu estratégias de modernização, atraindo Investimento Direto Estrangeiro, seguindo com uma moeda desvalorizada, além do baixo custo de mão de obra que permitiu ao país o desenvolvimento de indústrias, se tornando grande exportador de produtos de alta tecnologia

O espaço do idoso na cidade

Em muitos países, principalmente os mais desenvolvidos, o aumento da expectativa de vida é um fato constatado através das pesquisas públicas. No Brasil, a idade máxima atingida pela população é, em média, de aproximadamente setenta e dois anos. Porém, estes números foram resultado de um crescimento contínuo e persistente da expectativa de vida no país e que continua acontecendo. São consideradas idosas as pessoas com mais de sessenta anos. No Brasil, já existem investimentos em pesquisas e projetos voltados para os idosos, com necessidades peculiares, os recursos e equipamentos adequados para essa parte da população, mas não são suficientes. O projeto em questão busca resolver com a Arquitetura e o Urbanismo muitos dos problemas enfrentados na terceira idade. Sem excluir nenhuma faixa etária da população, mas dando ênfase aos idosos, o projeto estuda um espaço público já existente para dar-lhes acessibilidade e estrutura de serviços para serem realizadas as atividades de rotina e lazer. O projeto terá vários focos dentro de uma área dos bairros de Pinheiros e Vila Madalena, na cidade de São Paulo, para promover uma maior e mais eficiente inclusão do idoso no espaço urbano. O primeiro foco é uma praça que terá equipamentos que ajudam no físico, na saúde e no entretenimento dos idosos. O segundo é a revitalização da Rua Mourato Coelho, que liga a praça com a Feira Livre, além de todos os comércios e atividades propostos na rua e até o próprio bairro, atraindo mais atenção à praça. Este comercio, próximo, poderá proporcionar atividades de trabalho para os idosos, sendo um terceiro foco de tentativa de inclusão deste contingente no espaço urbano

Análise histomorfométrica do músculo cardíaco de ratos recém natos gerados por matrizes submetidas ao tabagismo passivo associado ao exercício

Maternal smoking during pregnancy causes heart changes, impaired fetal growth, spontaneous abortion and low birth weight. Even in pregnant women exposed to cigarette smoke these changes can be observed. But the exercise is to answer the increased fetal weight, besides the improvement of cardiorespiratory fitness of the pregnant and the fetus. The objective of this study was to analyze the ventricular muscle of young rats subjected to passive smoking associated with aquatic exercise. For the experiments used 24 female rats were divided into: GC (control), GE (exercise protocol in the water), GF(exposed to cigarette smoke) and GEF (exercise protocol on water and exposed to cigarette smoke). On the same day was held the 1st session of the experimental phase of the protocol of exposure to cigarette smoke, which consisted of 30 minutes twice a day, six days a week for three weeks, followed by the first session of the swimming program... (Complete abstract click electronic access below)

Natural compounds isolated from Brazilian plants are potent inhibitors of hepatitis C virus replication in vitro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Subjetividade, individualidade e singularidade na criança: um sujeito que se constitui socialmente

Considering the hypothesis that Bakhtin and his Circle's reflections can help us think about issues involving the field of Language Acquisition, in addition to the fact that there are only a few works developed within this perspective in Brazil, in this article, we intend to discuss the notions of subject, subjectivity, individuality and singularity, drawing on Bakhtin's theory. Thus, in order to make this discussion clearer, we bring data from the speech of young children, from 1.8 to 3 years old, who were filmed in natural contexts interacting with their parents and relatives. From these data, we could verify, among other things, that children, as individuals who constitute themselves as subjects in and through language, bring marks to their discourse, revealing their subjectivity (through lexical, morphological, syntactic or genre choices).

Modelagem da capacidade de transporte de sedimentos em latossolo férrico

Pós-graduação em Agronomia (Ciência do Solo) - FCAV

Comparative clinical sample preparation of DNA and RNA viral nucleic acids for a commercial deep sequencing system (Illumina MiSeq (R))

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Genetic structure and historical diversification of catfish Brachyplatystoma platynemum (Siluriformes: Pimelodidae) in the Amazon basin with implications for its conservation

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

First report of the characterization of the pathophysiological mechanisms caused by the freshwater catfish Pimelodus maculatus (order: Siluriformes)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Pharmacokinetics of flavanone glycosides after ingestion of single doses of fresh-squeezed orange juice versus commercially processed orange juice in healthy humans

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Greater level of physical activity associated with better cognitive function in hemodialysis in end stage renal disease

Patients with chronic kidney disease (CKD) have a lower exercise tolerance and poor functional capacity, carry on a sedentary lifestyle. Another important change found in patients with CKD is cognitive dysfunction. Physical inactivity has been associated with cognitive dysfunction in the general population, but few studies have evaluated this association in CKD. To assess the association between physical activity and cognitive function in patients with CKD on hemodialysis (HD). We evaluated 102 patients undergoing HD. The participants completed the International Physical Activity Questionnaire, which assesses the level of physical activity and the Mini Mental State Examination, used for cognitive screening. Patients were divided into three groups according to their level of physical activity (GI: active/GII: irregularly active/GIII: sedentary). It was applied logistic regression analysis and adopted as outcome variable the presence of cognitive impairment and preserving as independent variables those with a probability of statistical difference between groups of less than 0.1. It was considered statistically significant when p less than 0.05. The groups were similar in age, duration of HD, and smoking. Statistically significant difference regarding race, body mass index, diabetes mellitus, underlying disease and degree of cognitive impairment. Regarding laboratory data, the groups differed in terms of creatinine, glucose, hemoglobin and hematocrit. There was significant association with better physical activity and cognitive function, even adjusting for confounding variables. the highest level of physical activity was associated with better cognitive function in CKD patients undergoing HD.

Icodextrin reduces insulin resistance in non-diabetic patients undergoing automated peritoneal dialysis: results of a randomized controlled trial (STARCH)

Insulin resistance is a common risk factor in chronic kidney disease patients contributing to the high cardiovascular burden, even in the absence of diabetes. Glucose-based peritoneal dialysis (PD) solutions are thought to intensify insulin resistance due to the continuous glucose absorption from the peritoneal cavity. The aim of our study was to analyse the effect of the substitution of glucose for icodextrin on insulin resistance in non-diabetic PD patients in a multicentric randomized clinical trial. This was a multicenter, open-label study with balanced randomization (1:1) and two parallel-groups. Inclusion criteria were non-diabetic adult patients on automated peritoneal dialysis (APD) for at least 3 months on therapy prior to randomization. Patients assigned to the intervention group were treated with 2L of icodextrin 7.5%, and the control group with glucose 2.5% during the long dwell and, at night in the cycler, with a prescription of standard glucose-based PD solution only in both groups. The primary end-point was the change in insulin resistance measured by homeostatic model assessment (HOMA) index at 90 days. Sixty patients were included in the intervention (n = 33) or the control (n = 27) groups. There was no difference between groups at baseline. After adjustment for pre-intervention HOMA index levels, the group treated with icodextrin had the lower post-intervention levels at 90 days in both intention to treat [1.49 (95% CI: 1.23-1.74) versus 1.89 (95% CI: 1.62-2.17)], (F = 4.643, P = 0.03, partial η(2) = 0.078); and the treated analysis [1.47 (95% CI: 1.01-1.84) versus 2.18 (95% CI: 1.81-2.55)], (F = 7.488, P = 0.01, partial η(2) = 0.195). The substitution of glucose for icodextrin for the long dwell improved insulin resistance measured by HOMA index in non-diabetic APD patients.

Spironolactone is secure and reduces left ventricular hypertrophy in hemodialysis patients

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)