Pauson-Khand Adducts of N-Boc-propargylamine: A New Approach to 4,5-Disubstituted Cyclopentenones

A new approach to the synthesis of 4,5-disubstituted cyclopentenones is described. The strategy is based on the Pauson-Khand (PK) reaction of norbornadiene and N-Boc-propargylamine as alkyne with a masked leaving group, which can be eliminated at will. This approach to the synthesis of 4,5-disubstituted cyclopentenones overcomes the problem of using the alkylation to introduce the alpha-side-chain. As an example, prostane 13-epi-12-oxo-phytodienoic acid (13-epi-12-oxo-PDA) methyl ester was synthesized.

Pauson-Khand Adducts of N-Boc-propargylamine: A New Approach to 4,5-Disubstituted Cyclopentenones

A new approach to the synthesis of 4,5-disubstituted cyclopentenones is described. The strategy is based on the Pauson-Khand (PK) reaction of norbornadiene and N-Boc-propargylamine as alkyne with a masked leaving group, which can be eliminated at will. This approach to the synthesis of 4,5-disubstituted cyclopentenones overcomes the problem of using the alkylation to introduce the alpha-side-chain. As an example, prostane 13-epi-12-oxo-phytodienoic acid (13-epi-12-oxo-PDA) methyl ester was synthesized.

Biologia, religiositat i rituals (i II)

La religiositat pot actuar de mecanisme de cohesió, però sobretot a nivell de societats tribals on tots pertanyen a la mateixa comunitat

The role of motivational systems in community service involvement : initiating and sustaining factors and quality of experience /

Community service participation can have a positive impact on development, especially for youth. Although researchers have found positive outcomes, there has been a notable decline in youth participation over the past few years (Statistics Canada, 2000). Given the positive outcomes and current decline, it has been argued that youth should be encouraged to get involved in service activities. In the present study, quantitative and qualitative data were collected to determine factors that would help youth to initiate and sustain service, along with examining the quality of their experience. Eighty-two university undergraduate students (23 men), ranging in age from 17-20 years completed a 60-minute self-report questionnaire. Initiating and sustaining factors, motivational systems (similar to approach and avoidance dimensions), activity dimensions {Structure, Supportive Social Environment), quality of experience {Positive, Stress-Challenge), and future intention to participate in community service were measured. Eight participants also completed a 20-minute telephone interview to complement and expand on the quantitative data collected. Some initiating and sustaining factors were specific to individuals higher on the avoidance dimension, while others were relevant to those higher on the approach dimension. Several factors also were important to individuals regardless of their motivational system orientation. Positive quality of experience was related positively to experiencing a supportive social environment. In addition, women rated their community service as more positive than did men. A predicted interaction between the avoidance dimension and Structure in predicting positive quality of experience was not supported; however, positive quality of experience was predicted by the interaction of the approach dimension and Structure. A tested interaction between the avoidance dimension and Supportive Social Environment in predicting positive quality of experience was not supported. Similarly, a predicted interaction between the approach dimension and Supportive Social Environment in predicting positive experience quality was not supported. However, Supportive Social Environment was positively related to positive quality of experience. No support was found for a mediational role for positive quality of experience or stress-challenge quality of experience in exploring the relation between motivational orientation and fiiture intention to engage in service activities. The results of this study suggest that participating in a service environment that is supportive and provides the opportunity for social interactions with others would promote positive quality of experience and help youth sustain involvement. Thus, to help youth have positive experiences and to remain active in service, it is important for service agencies to promote these types of environments. In addition, some initiating and sustaining factors were specific to youth higher on the avoidance dimension and some were relevant to youth higher on the approach dimension. Therefore, service agencies may need to consider using different recruitment and retention strategies, depending on the type of youth they wish to recruit.

The neurobiology of meditation for the control of pain

La douleur est une expérience multidimensionnelle comportant des aspects sensoriels, émotionnels et cognitifs. Il a été montré que cette expérience peut être modulée par des facteurs psychologiques ou des interventions cognitives comme l’attention, la distraction, l’hypnose ou les attentes. La tradition orientale suggère également que la pratique de la méditation pourrait avoir des effets analgésiques. D’un point de vue théorique, plusieurs mécanismes pourraient expliquer ces effets. Cependant, très peu d’études ont testé ces hypothèses. Les études présentées dans cette thèse avaient donc pour objectif d’examiner les mécanismes analgésiques de la méditation. Dans un premier temps, une étude psychophysique a été réalisée afin de comparer les réponses à la douleur entre des adeptes de la méditation Zen et des sujets contrôles, dans différentes conditions attentionnelles. Durant la condition attentionnelle de type « mindful », les adeptes de la méditation ont présenté une plus faible sensibilité à la douleur, des réponses attentionnelles à la douleur atypiques et une diminution de la perception de la douleur associée à l’entraînement à la méditation. Une deuxième étude a été réalisée en imagerie par résonance magnétique fonctionnelle (IRMf) avec des groupes de participants similaires. Dans une condition sans méditation, les adeptes de la méditation ont présenté de plus fortes réponses nociceptives dans les régions primaires de la douleur. Les régions cérébrales associées aux processus d’évaluation, à la mémoire et aux émotions ont quant à elles montré une diminution d’activité. De plus, cette diminution était plus importante chez les adeptes de la méditation les plus expérimentés et elle était associée à des évaluations de douleur plus faibles. Par ailleurs, des changements de connectivité fonctionnelle entre le cortex préfrontal et une région primaires de la douleur étaient associés à la sensibilité à la douleur chez les adeptes de la méditation. Finalement, une étude d’imagerie cérébrale structurale (publiée comme deux études séparées) a été réalisée pour examiner les différences d’épaisseur corticale entre les groupes, pour des régions associées à la douleur. Les adeptes de la méditation ont présenté une épaisseur plus importante de matière grise dans plusieurs régions associées à la douleur et l’attention. De plus, ces différences étaient associées à une mesure expérientielle de l’attention, à la sensibilité à la douleur et à l’expérience de méditation. Dans l’ensemble, ces résultats suggèrent que la méditation pourrait influencer la perception de la douleur par des changements fonctionnels et physiques dans le cerveau. De plus, le patron d’activation et la modulation de l’expérience paraissent uniques en comparaison à ceux d’autres interventions, ce qui suggère qu’un état de détachement et un focus mental favorisent la dissociation entre les aspects désagréables et sensoriels d’un stimulus nociceptif.

Changements sociaux, instabilité et bien-être psychologique : le rôle de la trajectoire de la privation relative

Les comparaisons temporelles sont essentielles pour s’évaluer. Plusieurs études se sont intéressées aux conséquences négatives d’être insatisfait à la suite de comparaisons temporelles désavantageuses (c.-à.-d., à la privation relative). Peu d’étude a toutefois examiné l’évolution de ce sentiment d’insatisfaction. Le présent mémoire propose que ressentir différents niveaux d’insatisfaction au fil du temps, soit une trajectoire instable d’insatisfaction, affecte négativement le bien-être psychologique. Trois études expérimentales ont été menées. Les résultats révèlent que percevoir une trajectoire instable d’insatisfaction affecte négativement le bien-être psychologique. Une quatrième étude corrélationnelle a été menée au Kirghizstan afin d’examiner si les perceptions d’insatisfaction et d’instabilité mesurées à fil de l’histoire d’un groupe sont associées au bien-être psychologique lors de changements sociaux. Les résultats suggèrent que percevoir un haut niveau d’instabilité et d’insatisfaction au fil du temps est associé négativement au bien-être. Les implications théoriques et méthodologiques sont discutées.

Exclusão étnica, julgamento moral e emoções morais : estudo em adolescentes

Os pressupostos defendidos na declaração de Salamanca sobre a Educação Inclusiva não são fáceis de concretizar pois as pessoas, por causa de diferenças de sexo, etnia, aparência, etc, têm frequentemente condutas diferenciais. Um dos critérios sociais que mais provoca exclusão social são as diferenças étnicas, um fenómeno mais estudado pela psicologia social. Porém, a atitude de exclusão social pode estar relacionada com a competência moral dos indivíduos, uma relação que foi analisada neste estudo. Para isso recorremos ao suporte da psicologia moral que valoriza o papel das emoções na compreensão das condutas sociais, bem exemplificada nos estudos do vitimizador feliz (e.g., Arsenio & Kramer, 1992; Lourenço, 1998). Nas perspectivas mais recentes da psicologia moral tem sido atribuída grande ênfase à necessidade de analisar cognições e emoções nas condutas morais (e.g., Malti & Latzko, 2010; Turiel & Killen, 2010). Apoiados no estudo de Malti, Killen & Gasser (2012) sobre a exclusão social analisámos os julgamentos e as emoções morais de adolescentes em três contextos, etnia africana, etnia cigana e género, numa amostra de 45 adolescentes, com idades entre os 13 e os 19 anos, através da aplicação de uma versão traduzida da Survey Instrument for Measuring Judgments about Emotions about Exclusion (Malti, Killen & Gasser, 2009). Os jovens avaliaram a exclusão étnica como mais incorreta que a exclusão por género mas não foram encontradas diferenças nos juízos e emoções expressas pelos portugueses e estrangeiros. As emoções de culpa, tristeza, vergonha, atribuídas ao excludente confirmam a avaliação negativa da atitude de exclusão. Porém, a emoção normal que revela indiferença expressa que alguns jovens avaliaram positivamente a exclusão. A intensidade emocional intermédia das emoções atribuídas mostra inconsistência com o juízo moral. Relativamente ao excluído existe consenso pois as emoções de tristeza e raiva foram as mais atribuídas. As justificações dos juízos e emoções atribuídos são de tipo diverso, ou seja, argumentos morais de justiça e igualdade, argumentos de inclusão por empatia e argumentos convencionais relativos à coesão intragrupal. A atitude de exclusão não é estritamente moral pois também é vista em função de benefícios para o funcionamento do grupo. A relação complexa entre juízos, emoções e justificações requisita mais investigação de modo a percebermos melhor os processos psicológicos que induzem a conduta social.

Valores sociais e cidadania organizacional : um estudo com voluntários

Este estudo visa investigar a relação entre os Valores Sociais e os Comportamentos de Cidadania Organizacional. O objetivo para este estudo é procurar perceber a relação entre os valores sociais e o comportamento de cidadania organizacional. Em particular pretende-se testar a hipótese de que quanto mais elevados os valores de auto transcendência e de abertura à mudança, maior tendência para haver manifestação de comportamentos de cidadania organizacional em voluntários, assim como quanto mais valores de auto transcendência, maior a motivação para praticar voluntariado e, quanto maior a motivação, maior tendência para a manifestação de comportamentos de cidadania organizacional. Para testar estas hipóteses recorreu-se a um estudo correlacional, com uma amostra de 52 voluntários de várias associações, com idades compreendidas entre os 13 e os 58 anos de idade e de ambos os sexos, que responderam a 2 questionários: um para medir os valores sociais e outro para medir os comportamentos de cidadania organizacional e três questões sobre motivação para o voluntariado. Os resultados obtidos revelam correlação positiva entre a dimensão dos valores de Auto transcendência e todas as dimensões do Comportamento de Cidadania Organizacional, bem como a motivação ser um fator que influencia a manifestação de comportamentos de cidadania organizacional.

As políticas sociais na formação graduada do psicólogo no Piauí: análise curricular dos cursos

This research aimed to investigate the place of social policies in Psychology undergraduate programs from Piauí/Brazil. A documental study was done by analysing the Projeto Pedagógico de Curso (PPC) from five universities. Also, interviews were conducted, for each program, with a coordinator and a professor who teaches subjects related to social policies. The main results indicates that the Psychology undergraduate programs in Piauí are recent, created between the late 1990s and early 2000s, when professionals in this area were in demand. The social policies appear in PPC related to student profile; curricula emphasis, subjects and internships; albeit in a peripheral condition. Furthermore, disconnection between proposed profile and the curriculum; fragmentation and insufficient content about social policies; and predominance of clinical area were perceived in these institutions. It is noteworthy that health policies stand out in PPC while social assistance policy or other social policies were poorly mentioned. Therefore, the place of social policies must be reviewed in Psychology undergraduate programs from Piauí in order to include other social policies and improve the subjects articulation, assuming a central, critical and policy perspective

O contato em um click: ser-com em um mundo supervirtualizado

O presente estudo tem como objetivo compreender os sentidos da experiência de jovens e adultos com a interação social virtual, partindo de suas narrativas. Inspiradas nas ideias de Martin Heidegger, especialmente em seu seminário A Questão da Técnica , refletiremos sobre os modos de ser-com, em tempos de tecnologia, internet, consumo e hipermodernidade, contexto deste estudo, onde as coisas são vivenciadas em seu extremo (hiperconsumo, hipercorpo, hipermercado, hipercartões). Neste cenário, a Internet e as Tecnologias de Informação e Comunicação estão mediando, cada vez mais o contato do homem com o mundo, reconfigurando a vida em sociedade. Diante disso, apresentamos A Era do Click , em que são possibilitados novos meios de estar com os outros. Este é um estudo qualitativo, baseado na fenomenologia de Heidegger, por ser favorecedora da compreensão dos sentidos da experiência em relação à questão problematizada. Como estratégias de pesquisa foram utilizadas sondagem de campo e entrevistas individuais, inspiradas nas narrativas de Walter Benjamin. Cinco colaboradores relataram suas experiências de ser-com no mundo virtual. A partir de seus relatos foi possível compreender que o espaço virtual se revela como mais um lócus, dentre tantos, no cotidiano do ser do homem, em que emergem diferentes modos de ser-com. Dependendo de sua abertura, a proximidade ou o distanciamento tornam-se relativos, do mesmo modo que o pessoal e o impessoal, o próprio e o impróprio. Além disso, tornou-se claro que, a virtualidade pode ajudar a lidar com a solidão e a angústia temporariamente, da mesma forma que pode tornar-se uma barreira para um contato mais aprofundado e autêntico com os outros. Os colaboradores demonstraram uma atitude de serenidade, um poder dizer sim e não simultaneamente à técnica moderna, além de uma postura de meditar sobre os modos como se conectam. Questionamos as implicações em longo prazo da virtualização do contato, estimulando novos estudos, sob a luz da fenomenologia heideggeriana

Eu também sei atirar!: reflexões sobre a violência contra as mulheres e metodologias estético políticas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O sofrimento gera luta: o impacto da anemia falciforme e da vivência do adoecimento no desenvolvimento psíquico de portadores da doença

Pós-graduação em Saúde Coletiva - FMB

A Culture of Relationships: Early Care for Italian and American Children

A culture of childhood is a shared vision – an agreed upon vision – of the needs and rights of children, including ideas about how the people of the community can collectively nurture them and at the same time be renewed by them. In other words, it is a set of values, beliefs, and practices that people have created to guide their way of nurturing young children and their families. The vision is about investing in young children and investing in the supports and relationships that children need to learn and grow, both for the reason that children carry our future and because they carry our hopes and dreams for the future. These hopes and dreams begin with birth. Sensitive, emotionally available parents create the framework for interaction with their children by responding to the baby’s cues, engaging the baby in mutual gazes, and imitating the baby. The baby, born with a primary ability to share emotions with other human beings eagerly joins the relationship dance. The intimate family circle soon widens. Providers, teachers, and directors of early childhood programs become significant figures in children’s lives—implicit or explicit partners in a "relationship dance" (Edwards & Raikes, 2002). These close relationships are believed to be critical to healthy intellectual, emotional, social, and physical development in childhood and adolescence as well. These conclusions have been documented by diverse fields of science, ranging from cognitive science to communication studies and social and personality psychology. Close relationships contribute to security and trust, promote skill development and understanding, nurture healthy physical growth, infuse developing self-understanding and self-confidence, enable self-control and emotion regulation, and strengthen emotional connections with others that contribute to prosocial motivation (Dunn, 1993; Fogel, 1993; Thompson, 1996). Furthermore, many studies showing how relationship dysfunction is linked to child abuse and neglect, aggression, criminality, and other problems involving the lack of significant human connections (Shankoff & Meisels, 2000). In extending the dance of primary relationships to new relationships, a childcare teacher can play a primary role. The teacher makes the space ready--creating a beautiful place that causes everyone to feel like dancing. Gradually, as the dance between them becomes smooth and familiar, the teacher encourages the baby to try out more complex steps and learn how to dance to new compositions, beats, and tempos. As the baby alternates dancing sometimes with one or two partners, sometimes with many, the dance itself becomes a story about who the child has been and who the child is becoming, a reciprocal self created through close relationships.

Effects of consequenses on patterns of interlocked contingencies; A replication of a metacontingency experiment

The concept of metacontingency was taught to undergraduate students of Psychology by using a "game" simulation proposed originally by Vichi, Andery and Glenn (2009). Twenty-five students, distributed into three groups were exposed to six experimental sessions in which they had to make bets and divide the amounts gained. The three groups competed against each other for photocopies quotas. Two contingencies shifted over the sessions. Under Contingency B, the group would win points only if in the previous round each member had received the same amount of points and under Contingency A, winning was contingent on an unequal distribution of the points. We observed that proportional divisions predominated independent of the contingency in course. The manipulation of cultural consequences (winning or losing points) produced consistent modifications in two response categories: 1) choices of the value bet in each round, and 2) divisions of the points among group members. Controlling relations between cultural consequences and the behavior of dividing were statistically significant in one of the groups, whereas in the other two groups controlling relations were observed only in Contingency B. A review of the reinforcement criteria used in the original experiment is suggested.

Contribuições da Psicologia Histórico-Cultural para a formação e atuação do psicólogo em contexto de Educação Inclusiva

Este texto objetiva discutir contribuições da Psicologia Histórico-Cultural para a formação e a atuação do psicólogo junto à educação, num contexto de Educação Inclusiva. Destacam-se os fundamentos e princípios da educação para pessoas com deficiência, bem como postulados da teoria de Vigotski referentes à formação e à atuação dos psicólogos. Considera-se que a perspectiva teórica elaborada pelo autor soviético contribui por: destacar a transitoriedade dos eventos e fenômenos; atrelar o mundo das ideias, valores e representações à vida objetiva e à prática social; relacionar propostas educacionais a um dado projeto de sociedade; defender a possibilidade do desvendamento da constituição social do psiquismo e da possível intervenção sobre a mesma; requisitar uma condição de desenvolvimento humano sobre o patamar do homem cultural e livre. Por fim, destaca-se o fato de que a Educação Inclusiva deve se referir ao processo de apropriação e usufruto das produções humanas mais complexas, elaboradas nas diferentes áreas da vida e do conhecimento.