Efeito de citalopram no desenvolvimento larval de Chrysomya Megacephala (Fabricius, 1794) (Diptera: Calliphoridae) para uso forense

Chrysomya megacephala (Fabricius) é um díptero da família Calliphoridae, introduzido recentemente no Brasil, de forma acidental. Esta espécie possui grande importância médicosanitária por ser veiculadora de enteropatógenos como vírus, bactérias e helmintos; causar miíases facultativas; além de ser de fundamental importância na entomologia forense pelo fato de poder ser utilizada na estimativa do tempo de decomposição de cadáveres humanos, conhecido como intervalo pós-morte (IPM), ou na descoberta da causa da morte. Sabe-se que análises toxicológicas das larvas destes insetos podem detectar traços de substâncias lícitas ou não que se encontravam nos tecidos do cadáver, ingeridos antes da morte deste. Trabalhos recentes têm demonstrado que a presença de toxinas nos tecidos em decomposição pode alterar a taxa de desenvolvimento de insetos que utilizam-se destes como local de oviposição. Assim, testes preliminares utilizando dietas artificiais em laboratório são necessários para a criação de um banco de dados como padrão para investigar e quantificar as possíveis alterações no desenvolvimento de insetos coletados da cena criminal, para não gerar dados imprecisos sobre o IPM. No estágio larval, as moscas varejeiras competem ativamente por recursos alimentares. Nesse período, o substrato alimentar pode estar contaminado por substâncias químicas. O presente trabalho visa conhecer quais os possíveis efeitos da droga Citalopram, um antidepressivo que vem sendo utilizado em larga escala em casos de suicídio, sobre o tempo de desenvolvimento larval de C. megacephala até a pupação, frente a diferentes dosagens que serão utilizadas, além da obtenção de dados envolvendo porcentagem de emergência e razão social para os adultos emergidos, para cada um doss diferentes tratamentos

Resistência de cultivares de milho convencional e transgênico à Diatraea saccharalis (Fabricius, 1794) (Lepidoptera: Crambidae)

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

The laurent series for the quaternionic case

The present work has the scope to show the Laurent Series for quaternionic functions. It will be shown that the Laurent Series for the Quaternionic Case is analogous to the textbook case of Complex Analysis [1]-[2] already well established.

Desempenho reprodutivo e diferenciação gonadal em piau-três-pintas, Leporinus friderici, Bloch 1794

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Dinâmica populacional, distribuição espacial e plano de amostragem sequencial de Euschistus heros (Fabricius, 1794) (Heteroptera: Pentatomidae) em cultivares de soja

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Modelos de previsão de ocorrência de adultos de diatraea saccharalis (Fabricius, 1794) (Lepidoptera: Crambidae) em cana-de-açúcar (Saccharum spp.)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Underlying Event measurements in pp collisions at root s=0.9 and 7 TeV with the ALICE experiment at the LHC

We present measurements of Underlying Event observables in pp collisions at root s = 0 : 9 and 7 TeV. The analysis is performed as a function of the highest charged-particle transverse momentum p(T),L-T in the event. Different regions are defined with respect to the azimuthal direction of the leading (highest transverse momentum) track: Toward, Transverse and Away. The Toward and Away regions collect the fragmentation products of the hardest partonic interaction. The Transverse region is expected to be most sensitive to the Underlying Event activity. The study is performed with charged particles above three different p(T) thresholds: 0.15, 0.5 and 1.0 GeV/c. In the Transverse region we observe an increase in the multiplicity of a factor 2-3 between the lower and higher collision energies, depending on the track p(T) threshold considered. Data are compared to PYTHIA 6.4, PYTHIA 8.1 and PHOJET. On average, all models considered underestimate the multiplicity and summed p(T) in the Transverse region by about 10-30%.

Measurement of prompt J/psi and beauty hadron production cross sections at mid-rapidity in pp collisions at root s=7 TeV

The ALICE experiment at the LHC has studied J/psi production at mid-rapidity in pp collisions at root s = 7 TeV through its electron pair decay on a data sample corresponding to an integrated luminosity L-int = 5.6 nb(-1). The fraction of J/psi from the decay of long-lived beauty hadrons was determined for J/psi candidates with transverse momentum p(t) > 1,3 GeV/c and rapidity vertical bar y vertical bar < 0.9. The cross section for prompt J/psi mesons, i.e. directly produced J/psi and prompt decays of heavier charmonium states such as the psi(2S) and chi(c) resonances, is sigma(prompt J/psi) (p(t) > 1.3 GeV/c, vertical bar y vertical bar < 0.9) = 8.3 +/- 0.8(stat.) +/- 1.1 (syst.)(-1.4)(+1.5) (syst. pol.) mu b. The cross section for the production of b-hadrons decaying to J/psi with p(t) > 1.3 GeV/c and vertical bar y vertical bar < 0.9 is a sigma(J/psi <- hB) (p(t) > 1.3 GeV/c, vertical bar y vertical bar < 0.9) = 1.46 +/- 0.38 (stat.)(-0.32)(+0.26) (syst.) mu b. The results are compared to QCD model predictions. The shape of the p(t) and y distributions of b-quarks predicted by perturbative QCD model calculations are used to extrapolate the measured cross section to derive the b (b) over bar pair total cross section and d sigma/dy at mid-rapidity.

The evolutionary implications of hemipenial morphology of rattlesnake Crotalus durissus terrificus (Laurent, 1768) (Serpentes: Viperidae: Crotalinae)

Most amniotes vertebrates have an intromittent organ to deliver semen. The reptile Sphenodon and most birds lost the ancestral penis and developed a cloaca-cloaca mating. Known as hemipenises, the copulatory organ of Squamata shows unique features between the amniotes intromittent organ. They are the only paired intromittent organs across amniotes and are fully inverted and encapsulated in the tail when not in use. The histology and ultrastructure of the hemipenes of Crotalus durissus rattlesnake is described as the evolutionary implications of the main features discussed. The organization of hemipenis of Crotalus durissus terrificus in two concentric corpora cavernosa is similar to other Squamata but differ markedly from the organization of the penis found in crocodilians, testudinata, birds and mammals. Based on the available data, the penis of the ancestral amniotes was made of connective tissue and the incorporation of smooth muscle in the framework of the sinusoids occurred independently in mammals and Crotalus durissus. The propulsor action of the muscle retractor penis basalis was confirmed and therefore the named should be changed to musculus hemipenis propulsor.The retractor penis magnus found in Squamata has no homology to the retractor penis of mammals, although both are responsible for the retraction of the copulatory organ

Un proyecto de arsenal para la Barceloneta (1743)

[ES] En 1743 el ingeniero militar Miguel Marín diseñó un arsenal naval en Barcelona. En este artículo se estudia el contexto inmediato de este proyecto. Primeramente, la voluntad de trasladar la principal base naval mediterránea de Cartagena a la capital catalana. En segundo lugar, la relación centro-periferia y el papel del lobby catalán dentro del proceso.

Le problematiche legate alla traduzione della letteratura per l'infanzia: il caso di "A copier 100 fois" di Antoine Dole

Il presente elaborato finale è la proposta di traduzione delle prime 35 pagine del libro di Antoine Dole intitolato À copier 100 fois. In seguito a un suo inquadramento nel panorama della letteratura per l'infanzia e a una breve digressione sullo sviluppo della traduzione relativa a quest'ambito, l'obiettivo è quello di mostrare le strategie traduttive adottate elencandole e descrivendole all'interno del commento alla traduzione.

Cannabinoid receptor 1 and 2 agonists increase lipid accumulation in hepatocytes

Cannabinoid receptors CB1 and CB2 are expressed in the liver, but their regulation in fatty hepatocytes is poorly documented. The aim of this study was to investigate the effects of selective CB1 or CB2 agonists on the expression of key regulators of lipid metabolism.

Biomedical nanoparticles modulate specific CD4+ T cell stimulation by inhibition of antigen processing in dendritic cells

Understanding how nanoparticles may affect immune responses is an essential prerequisite to developing novel clinical applications. To investigate nanoparticle-dependent outcomes on immune responses, dendritic cells (DCs) were treated with model biomedical poly(vinylalcohol)-coated super-paramagnetic iron oxide nanoparticles (PVA-SPIONs). PVA-SPIONs uptake by human monocyte-derived DCs (MDDCs) was analyzed by flow cytometry (FACS) and advanced imaging techniques. Viability, activation, function, and stimulatory capacity of MDDCs were assessed by FACS and an in vitro CD4+ T cell assay. PVA-SPION uptake was dose-dependent, decreased by lipopolysaccharide (LPS)-induced MDDC maturation at higher particle concentrations, and was inhibited by cytochalasin D pre-treatment. PVA-SPIONs did not alter surface marker expression (CD80, CD83, CD86, myeloid/plasmacytoid DC markers) or antigen-uptake, but decreased the capacity of MDDCs to process antigen, stimulate CD4+ T cells, and induce cytokines. The decreased antigen processing and CD4+ T cell stimulation capability of MDDCs following PVA-SPION treatment suggests that MDDCs may revert to a more functionally immature state following particle exposure.

Transjugular intravascular ultrasound for the evaluation of hepatic vasculature and parenchyma in patients with chronic liver disease

Background The evaluation of the hepatic parenchyma in patients with chronic liver disease is important to assess the extension, localization and relationship with adjacent anatomical structures of possible lesions. This is usually performed with conventional abdominal ultrasound, CT-scan or magnetic resonance imaging. In this context, the feasibility and the safety of intravascular ultrasound in the liver have not been assessed yet. Methods We tested the safety and performance of an intracardiac echography (ICE) catheter applied by a transjugular approach into the hepatic veins in patients with chronic liver disease undergoing hepatic hemodynamic measurements. Results Five patients were enrolled in this pilot study. The insertion of the ICE catheter was possible into the right and middle, but not into the left hepatic vein. The position of the ICE was followed using fluoroscopy and external conventional ultrasound. Accurate imaging of focal hepatic parenchymal lesions, Doppler ultrasound of surrounding blood vessels and assessment of liver surface and ascites were achieved without complications. Conclusions This study demonstrated that a diagnostic approach using an ICE device inserted in the hepatic veins is feasible, safe and well tolerated. However, it remains for the moment only an experimental investigative tool. Whether ICE adds further information regarding parenchymal lesions and associated vascular alterations as compared to other techniques, needs additional investigation.