987 resultados para Genomic library
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Brief history of Forrest Spaulding, head of the Des Moines Public Library from 1917-1952
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Quarterly update for State Library patrons.
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A mediados de Marzo de este año 2006 estuvo en España, dando conferencias en Madrid y Barcelona, Laura Campbell, subdirectora y jefa de información de la Library of Congress (LoC) de los Estados Unidos.
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The integration of the Human Immunodeficiency Virus (HIV) genetic information into the host genome is fundamental for its replication and long-term persistence in the host. Isolating and characterizing the integration sites can be useful for obtaining data such as identifying the specific genomic location of integration or understanding the forces dictating HIV integration site selection. The methods outlined in this article describe a highly efficient and precise technique for identifying HIV integration sites in the host genome on a small scale using molecular cloning techniques and standard sequencing or on a massive scale using 454 pyrosequencing.
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Special investigation of the City of Collins Library for the period July 1, 2007 through July 30, 2009
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Quarterly update for State Library patrons.
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Quarterly update for State Library patrons.
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Els dies 11 i 12 d'agost va tenir lloc a Copenhaguen, Dinamarca, el seminari de treball Library and Information Science Education in Europe: ¿Issues in joint curriculum development and Bologna perspectives¿. Aquest seminari, que va estar coordinat per la Royal School of Library and Information Science de Dinamarca, amb la col·laboració de l'European Association for Library and Information Education and Research (EUCLID), es va organitzar en el marc d'un projecte europeu subvencionat pel programa Sòcrates. La Facultat de Biblioteconomia i Documentació de la Universitat de Barcelona, present entre 2001 i 2005 en la Junta de Govern de l'EUCLID, va participar-hi com a soci del projecte. L'objectiu del seminari era aplegar una cinquantena d'experts europeus de l'àrea de Biblioteconomia i Documentació ¿tots ells professors d'escoles i de facultats d'universitats europees¿ per discutir qüestions relacionades amb els plans d'estudis dels ensenyaments des de la perspectiva del procés de Bolonya. El seminari consistí en dues conferències i en les reunions de treball de dotze grups formats per experts que examinaren dotze grans temes ¿prèviament acordats pels organitzadors de l'esdeveniment¿ relacionats amb els plans d'estudis d'aquells ensenyaments.
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This year, IFLA's World Library and Information Congress (WLIC) was held in Durban, South Africa, under the title ¿Libraries for the future: progress, development and partnerships¿. The association thus continued its policy of holding the event in different continents: Buenos Aires (South America) 2004, Oslo (Europe) 2005, Seoul (Asia) 2006, Durban (Africa) 2007, Quebec (North America) 2008, Milan (Europe) 2009 and Brisbane (Oceania) 2010.
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Quarterly update for State Library patrons.
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Quarterly State Library Update for patrons.
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BACKGROUND: The mouse inbred line C57BL/6J is widely used in mouse genetics and its genome has been incorporated into many genetic reference populations. More recently large initiatives such as the International Knockout Mouse Consortium (IKMC) are using the C57BL/6N mouse strain to generate null alleles for all mouse genes. Hence both strains are now widely used in mouse genetics studies. Here we perform a comprehensive genomic and phenotypic analysis of the two strains to identify differences that may influence their underlying genetic mechanisms. RESULTS: We undertake genome sequence comparisons of C57BL/6J and C57BL/6N to identify SNPs, indels and structural variants, with a focus on identifying all coding variants. We annotate 34 SNPs and 2 indels that distinguish C57BL/6J and C57BL/6N coding sequences, as well as 15 structural variants that overlap a gene. In parallel we assess the comparative phenotypes of the two inbred lines utilizing the EMPReSSslim phenotyping pipeline, a broad based assessment encompassing diverse biological systems. We perform additional secondary phenotyping assessments to explore other phenotype domains and to elaborate phenotype differences identified in the primary assessment. We uncover significant phenotypic differences between the two lines, replicated across multiple centers, in a number of physiological, biochemical and behavioral systems. CONCLUSIONS: Comparison of C57BL/6J and C57BL/6N demonstrates a range of phenotypic differences that have the potential to impact upon penetrance and expressivity of mutational effects in these strains. Moreover, the sequence variants we identify provide a set of candidate genes for the phenotypic differences observed between the two strains.
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In its long and irregular transition, from traditional library to the electronic book we have seen combining and alternating the hybrid, electronic and most recently the digital libraries. All these concepts which are combining and are conditioning each other, are referring to methods of organization and use of an informational content (which exists or not in an informational structure).
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Legislation passed during the 2010 legislative session required a study of ways to streamline state-funded library operations and services. The Iowa Library Association was asked to lead this endeavor and named a committee to carry out the study. The study resulted in the development of a plan for reorganization, which is outlined in the Iowa Library Services Reorganization Report. The Iowa Library Reorganization Committee was representative of the Library Services Areas, the State Library of Iowa, and public libraries of all sizes from all around the state. The president of the Iowa Library Association and the State Librarian also served as members of the Committee. The report was submitted to members of the Iowa legislature on November 1, 2010.