Co-stressors chilling and high light increase photooxidative stress in diuron-treated red alga Kappaphycus alvarezii but with lower involvement of H(2)O(2)

Diuron is one of the most commonly found N-phenylurea herbicides in marine/estuarine waters that promotes toxic effects by inhibiting photosynthesis and affecting the production of reactive oxygen species (ROS) in autotrophs. Since photo- and thermoacclimation are also ROS-mediated processes, this work evaluates a hypothetical additive effect of high light (HL) and chilling (12 degrees C) on 50 nM diuron toxicity to the highly-photosynthetically active apices of the red alga Kappaphycus alvarezii. Additive inhibition of photosynthesis was mainly evidenced by significant decreases of quantum yield of photosystem II and electron transfer rates upon co-stressors exposure to diuron-treated algae. Under extreme 12 degrees C/HL/diuron conditions, unexpected lower correlations between H(2)O(2) concentrations in seawater and radical-sensitive protein thiols were concomitantly measured with the highest indexes of photoinhibition (parameter beta). Altogether, these data support the hypothesis that co-stressors chilling/HL additively inhibit photosynthesis in diuron-exposed K. alvarezii but with less involvement of H(2)O(2) in injury effects than with only chilling or HL. (C) 2010 Elsevier Inc. All rights reserved.

Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia

Schizophrenia is likely to be a consequence of serial alterations in a number of genes that, together with environmental factors, will lead to the establishment of the illness. The dorsolateral prefrontal cortex (Brodmann`s Area 46) is implicated in schizophrenia and executes high functions such as working memory, differentiation of conflicting thoughts, determination of right and wrong concepts, correct social behavior and personality expression. We performed a comparative proteome analysis using two-dimensional gel electrophoresis of pools from 9 schizophrenia and 7 healthy control patients` dorsolateral prefrontal cortex aiming to identify, by mass spectrometry, alterations in protein expression that could be related to the disease. In schizophrenia-derived samples, our analysis revealed 10 downregulated and 14 upregulated proteins. These included alterations previously implicated in schizophrenia, such as oligodendrocyte-related proteins (myelin basic protein and transferrin), as well as malate dehydrogenase, aconitase, ATP synthase subunits and cytoskeleton-related proteins. Also, six new putative disease markers were identified, including energy metabolism, cytoskeleton and cell signaling proteins. Our data not only reinforces the involvement of proteins previously implicated in schizophrenia, but also suggests new markers, providing further information to foster the comprehension of this important disease. (C) 2008 Elsevier Ltd. All rights reserved.

The role of entrepreneurial networking on internationalization of a micro-sized Born Global Swedish fashion company : A narrative ethnographic research

Background: In recent studies a lot of attention is drawn to the connection between networking and entrepreneurship. Many scholars consider successful business and networking inseparable. Taking into consideration the topicality of the two notions discussed above the authors of this thesis decided to conduct the research dedicated to these phenomena in the field that interests them most – in the field of Swedish fashion. Purpose: The purpose of the thesis is to gain a deeper insight into entrepreneur’s experiences to point out the role of entrepreneurial networking in the process of internationalization of a micro-sized Swedish fashion company and to contribute to the research in this field by telling its unique story. Method: To achieve the purpose of the research a narrative ethnographic research was conducted. This research strategy was chosen because it suits the purpose best by giving an opportunity to get fresh insights into the field of entrepreneurial networking from the point of view of the entrepreneur. The data collected has a narrative nature therefore narrative analysis is used to present it. The methods of gathering the data are face-to-face interview and documents. Conclusion: we can define the most important role of entrepreneurial networking on the internationalization process of Odeur as an effective accelerator and a tool to fulfil the knowledge and expertise gaps in certain areas through other actors in the network.

Wolves in sheeps' clothing: Creationist manipulation of Kansas science standards

So the question that animates this paper is this: what happens when a state's education policy seeks to make popular social and religious values a central part of its education standards in direct confrontation with the Establishment Clause of the First Amendment of the U.S. Constitution? I will try to answer that question in three ways. First, I will examine the tactics used in the manipulation of curricula to reflect social and religious values, with special focus on the Kansas case. Second, I will try to ascertain the determinants of success in these efforts; under what conditions are movements to impose creation science on public school curricula likely to succeed, and when to fail? Third, I will try to place these struggles over educational curricula, and between religion and science, in broader context, focusing on what they tell us about the nature of public policy making in the contemporary United States.

Involvement of free radicals in peroxidatic reactions catalyzed by chloroperoxidase

The mechanism of chloroperoxidase (CPO)-catalyzed peroxidatic reactions of several substituted hydroquinones was studied at various hydrogen peroxide concentrations. The pathway was studied using cytochrome c as the radical trapping agent. As the hydroquinones became more hindered there was a difference in the amount of radicals trapped. For hydroquinone, 59.3% radical pathway, and methylhydroquinone, 81.4% radical, the difference in radicals trapped is due to a difference in pathway. For 2,3-dimethylhydroquinone (75.4%), trimethylhydroquinone (44.5%), and t-butylhydroquinone (0%) other non-peroxidatic reactions are noticed. Thus, for the more substituted hydroquinones the difference in radicals trapped can not be assigned to a difference in radical pathway. Also, there were problems drawing conclusions for this system due to the catalytic reaction of hydrogen peroxide. The radical trapping ability of 2,4,6-trimethylphenol was investigated for various other substrates. TMP reacted with the radicals generated in the enzymatic reactions of phenol, resorcinol, and m-methoxyphenol. Thus, this TMP system offers further potential as another radical trapping agent for use in these studies.

Avaliação da aplicabilidade da escala New Involvement Profile para mensuração do envolvimento do consumidor na cidade de Porto Alegre

O estudo do envolvimento do consumidor representa um dos tópicos mais importantes de pesquisa para aqueles que visam entender a forma como os seres humanos realizam suas decisões de compra. O envolvimento determina a quantidade de esforços empregados no processo de tomada de decisão, e apresenta importantes implicações tanto para o âmbito acadêmico quanto para o meio gerencial. No que diz respeito ao ambiente brasileiro, no entanto, foram poucos os trabalhos que se dedicaram exclusivamente a esse tema, não havendo, até o início desta pesquisa, nenhuma escala para mensuração de envolvimento validada para este cenário. O objetivo deste estudo é a avaliação da aplicabilidade da escala de Jain & Srinivasan (1990) na cidade de Porto Alegre. Tal escala, denominada New Involvement Profile (NIP), pode ser utilizada para mensuração do envolvimento de consumidores com diferentes categorias de produtos. Para esta pesquisa, mensurou-se o envolvimento com relação aos produtos cerveja, chocolate, corte de cabelo, CD, aparelho de televisão, detergente, shampoo e pilha. A escala NIP foi reaplicada a uma amostra de 420 (quatrocentos e vinte) respondentes em diversos bairros desta cidade. A qualidade e a robustez da escala de Jain & Srinivasan (1990) foram comprovadas através de testes de confiabilidade e verificações da validade de conteúdo e de constructo, englobando validade convergente e discriminante de cada dimensão da escala. Tal avaliação foi complementada a partir da relação existente entre os níveis de envolvimento encontrados e os pressupostos teóricos acerca desse conceito – tipos e determinates, bem como da comparação entre esses níveis e aqueles obtidos pelos mesmos produtos em estudos semelhantes.

A influência da exportação no desenvolvimento de arranjos produtivos locais de moda no estado do Rio de Janeiro

In recent years, clusters have become a central part in discussions about local and regional economic development, as well as in the elaboration of public policies for generating jobs and income. Concurrent with the discussions about clusters, the subject globalization has also received growing attention from the media in the academic and government fields. Different aspects are considered in the discussions regarding globalization and one of the subjects is the insertion of local economies into international commerce. One of these ways of insertion is by global value chains. This term began to be used at the end of 90s, and refers to the productive value chains dispersed throughout the world, but with integrated production and commercialization. The aim of this thesis is to understand how the exportation process influences the development of fashion clusters, this being done by the insertion of these clusters into the global value chains. Each year, the Brazilian fashion sector seeks to broaden their participation in the global economy by means of insertion into the global value chains. This insertion, however, has caused impacts in specialized clusters of garment manufacturers, such as beach fashion, jeans and women¿s clothing. As a way of identifying these impacts, three cluster manufacturers were studied in the state of Rio de Janeiro, namely Cabo Frio, São Gonçalo and Niterói. The impacts of internationalization on the companies integrated into these three clusters were explored by means of a six-month field study, including semistructured interviews. This internationalization occurs either by direct exportation or by means of inserting these companies into the global value chains. The results of the study points out the opportunities and threats to these companies, as well as shows the importance of more adequate public policies for the development of Brazilian fashion clusters. Among these threats, the possibility of inserting these cluster companies into the global value chains in a captive manner (Gereffi, Humphrey, Sturgeon, 2005) was singled out, placing them ¿under control¿ of the exporting companies. As for opportunities, the participation of government support agencies and improvements in fashion show good alternatives for inserting these companies into the global value chains, making possible autonomous and competitive performance.

The stakeholders‟ involvement in the process of building and maintaining a destination brand

A destination is a place that attracts visitors for a temporary stay to participate in tourism related activities or non- activities. Globalization, the increased number of travelers and the increased buying power have increased the competition between the destinations and the destinations have become more substitutable. It has been agreed that destinations can be branded as well as products and to be competitive it is getting common to brand destinations. Destination Marketing Organizations (DMOs) are responsible for the marketing of an identifiable destination. The purpose of this study is to present an exploratory study of how a destination marketing organization creates and builds a strong destination brand and how the stakeholders have been involved in the process. The study is done with a qualitative case study approach. The case study was chosen as the research method to make a detailed and intensive analysis of the research objective, in this case the destination brand of Brazil and its stakeholders.

São Paulo Fashion Week e a transformação da indústria criativa da moda no Brasil

Transformações relacionadas às Indústrias Criativas (ICs) dos países emergentes têm sido objeto de interesse de estudos acadêmicos. Entretanto, pesquisadores dos Estudos Organizacionais ainda não realizaram investigações relacionadas a transformações na Indústria Criativa da Moda (ICM). A ICM vem, de fato, sendo negligenciada por esse campo de estudos. Este trabalho visa, portanto, preencher essa lacuna. Para tanto, realizou-se um estudo de caso descritivo sobre a SPFW (São Paulo Fashion Week). O objetivo do estudo foi examinar como agentes relacionados a essa semana de moda internacional contribuíram, por meio de atividades discursivas, para transformar a prática da ICM no Brasil – de copiar moda de luxo estrangeira a desenvolver moda “nacional”. Como perspectiva teórica foi adotada a lente teórica “Discurso e Instituições”. Foram analisados textos produzidos por agentes relacionados à SPFW entre 1994 a 2011, tais como press releases, documentários e reportagens sobre os eventos. Foram realizadas, ainda, entrevistas com 13 profissionais do setor. O estudo levou a concluir que agentes relacionados à SPFW transformaram a prática da ICM pela produção e disseminação de textos que formaram o discurso “A ICM do Brasil produz moda própria, contemporânea e sofisticada” – de acordo com seus interesses. A aceitação dessa “nova realidade” pelos indivíduos, constituída por esse discurso, possibilitou um novo entendimento sobre a prática de produção da ICM: ser recomendável desenvolver moda própria, ao invés de ser aceitável copiar moda estrangeira. Tal formação discursiva, todavia, não ocorreu sem conflitos e disputas entre agentes. Também não ocorreu num vácuo social, mas foi favorecida por acontecimentos no contexto da globalização: crise da indústria têxtil, aumento na disponibilidade de informações, aversão à chegada de bens de luxo importados ao país, boom das modelos brasileiras.

A comparative study of internationalization potential for Italian SMEs in the fashion industry in Brazil and Russia

Este estudo tem como objetivo desenvolver uma análise comparativa do potencial de internacionalização na Rússia e no Brasil para as PME italianas que operam na indústria da moda. Depois de apresentar ao leitor as principais áreas cobertas, tais como, o contexto, a metodologia e revisão da literatura, é fornecido um panorama macroeconômico das áreas geográficas composto, englobando um estudo específico sobre o estado atual da economia e da demanda para os bens italianos. O estudo, introduzindo o leitor na indústria de moda italiana, suas principais características e o desempenho atual, já evidencia a busca pela internacionalização. As conclusões decorrentes das análises macroeconômicas funcionam como introdução à visão geral da indústria de moda italiana, uma indústria que representa, fortemente, o "Made in Italy" no exterior. A breve análise da história desta indústria, principais características e situação atual irão, então, sugerir que a internacionalização é o caminho mais viável às PME, para se recuperarem dos anos turbulentos da crise. Entre o vasto conjunto de opções geográficas que as PME têm para abraçar internacionalização, este estudo tem como objetivo fornecer duas análises sobre a indústria da moda: o mercado russo e o brasileiro. A análise, com base no quadro de capacidade de ‘resposta internacional’ proposto por Bartlet e Ghoshal (1989), apresenta os resultados de um conjunto de pesquisas e entrevistas realizadas no Brasil, na Itália e na Rússia, sob a forma de uma análise comparativa dos dois mercados-alvo. A análise evidenciará os drivers de mercado, custo, competitividade e legislação que justificam o processo de internacionalização em ambos os mercados. Os resultados levam à conclusão e às recomendações que os dois mercados representam duas oportunidades muito diferentes para as PME da indústria da moda italiana.

Cyclicality of SME Lending and Government Involvement in Banks

Recent regulatory efforts aim at lowering the cyclicality of bank lending because of its potential detrimental effects on financial stability and the real economy. We investigate the cyclicality of SME lending by local banks with vs. without a public mandate, controlling for location, size, loan maturity, funding structure, liquidity, profitability, and credit demand-side factors. The public mandate is set by local governments and stipulates a deviation from strict profit maximization and a sustainable provision of financial services to local customers. We find that banks with a public mandate are 25 percent less cyclical than other local banks. The result is credit supply-side driven and especially strong for savings banks with high liquidity and stable deposit funding. Our findings have implications for the banking structure, financial stability and the finance-growth nexus in a local context.

Cyclicality of SME lending and government involvement in banks

Recent regulatory efforts aim at lowering the cyclicality of bank lending because of its potential detrimental effects on financial stability and the real economy. We investigate the cyclicality of SME lending by local banks with vs. without a public mandate, controlling for location, size, loan maturity, funding structure, liquidity, profitability, and credit demand-side factors. The public mandate is set by local governments and stipulates a deviation from strict profit maximization and a sustainable provision of financial services to local customers. We find that banks with a public mandate are 25 percent less cyclical than other local banks. The result is credit supply-side driven and especially strong for savings banks with high liquidity and stable deposit funding. Our findings have implications for the banking structure, financial stability and the finance-growth nexus in a local context.

São Paulo fashion district: modelos de parcerias para viabilizar um polo criativo de moda em São Paulo

Este artigo apresenta modelos de parcerias que podem ser celebrados pela prefeitura de São Paulo com a finalidade de estruturar um cluster de moda na região da luz, centro do município. A escolha do setor têxtil para a proposta se baseou na importância que esta indústria tem na cidade de São Paulo e no seu potencial de crescimento, tendo em vista a baixa qualificação e inovação apontada pelos dados do setor. A delimitação da região da luz considerou a vocação da região já ocupada pelo comércio de moda e por ser uma região estratégica para o município. Com esse artigo objetiva-se projetar a cidade de São Paulo como grande produtor de moda no mundo e recuperar a região da luz por meio de parcerias com parceiros privados, ou seja, com ações com baixo impacto no orçamento municipal.