990 resultados para Slattery, Charles Lewis, Bp., 1867-1930.


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IEECAS SKLLQG

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研究了HIRFL提供的12C6+离子辐照C57BL/6J小鼠右后腿移植的Lewis肿瘤的生长延迟和碳离子辐照对Lewis肿瘤小鼠寿命的延长.结果表明,碳离子照射的小鼠肿瘤生长体积明显地小于对照的体积.在剂量相同、分次数辐照越多时,肿瘤生长就越缓慢,肿瘤抑制就越高.在辐照分次数相同时,不同剂量对受照肿瘤生长体积未产生差异.在4Gy×3,8Gy×3和12Gy×2组3种辐照剂量下,小鼠寿命的P值小于0.05;可知小鼠的寿命延长具有统计学意义.

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DNA damage and cell reproductive death determined by alkaline comet and clonogenic survival assays were examined in Lewis lung carcinoma cells after exposure to 89.63 MeV/u carbon ion and 6 MV X-ray irradiations, respectively. Based on the survival data, Lewis lung carcinoma cells were verified to be more radiosensitive to the carbon ion beam than to the X-ray irradiation. The relative biological effectiveness (RBE) value, which was up to 1.77 at 10% survival level, showed that the DNA damage induced by the high-LET carbon ion beam was more remarkable than that induced by the low-LET X-ray irradiation. The dose response curves of '' Tail DNA (%)'' (TD) and "Olive tail moment" (OTM) for the carbon ion irradiation showed saturation beyond about 8 Gy. This behavior was not found in the X-ray curves. Additionally, the carbon ion beam produced a lower survival fraction at 2 Gy (SF2) value and a higher initial Olive tail moment 2 Gy (OTM2) than those for the X-ray irradiation. These results suggest that carbon ion beams having high-LET values produced more severe cell reproductive death and DNA damage in Lewis lung carcinoma cells in comparison with X-rays and comet assay might be an effective predictive test even combining with clonogenic assay to assess cellular radio sensitivity

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根据太子河流域降水和产汇流特点 ,利用流域试点区观音阁水库枯季入库径流量、上游汛期降水量、汛末入库径流量和枯季降水量等实测系列资料 ,对所建立的BP神经网络模型进行训练、检验和对比分析 ,结果表明 ,所建立的枯季径流BP预报模型是合理可行的 ,并且具备较高的精度 ,可在同类地区推广使用

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由于影响因素的复杂性 ,预测降水量具有相当的难度。在假设区域长时间内降水量和蒸发量保持平衡的基础上 ,用 BP人工神经网络建立了陕西省汉中市的降水量预测模型 ,根据前 3个月降水量和蒸发量对降水量资料进行了模拟预测 ,结果认为其准确率为 84% ,合格率为 10 0 %。

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Lewis base modification strategy on rare earth ternary catalyst was disclosed to enhance nucleophilic ability of active center during copolymerization of carbon dioxide and propylene oxide (PO), poly(propylene carbonate) (PPC) with H-T linkages over 83%, and number-average molecular weight (M-n) up to 100 kg/mol was synthesized at room temperature using Y(CCl3OO)(3)-ZnEt2-glycerine catalyst and 1,10-phenanthroline (PHEN) cocatalyst. Coordination of PHEN with active Zinc center enhanced the nucleophilic ability of the metal carbonate, which became more regio-specific in attacking carbon in PO, leading to PPC with improved H-T linkages.