Government spending and re-election: Quasi-experimental evidence from Brazilian municipalities

Does additional government spending improve the electoral chances of incumbent politicalparties? This paper provides the first quasi-experimental evidence on this question. Our researchdesign exploits discontinuities in federal funding to local governments in Brazil around severalpopulation cutoffs over the period 1982-1985. We show that extra fiscal transfers resulted in a20% increase in local government spending per capita, and an increase of about 10 percentagepoints in the re-election probability of local incumbent parties. In the context of an agency modelof electoral accountability, as well as existing results indicating that the revenue jumps studiedhere had positive impacts on education outcomes and earnings, these results suggest that expectedelectoral rewards encouraged incumbents to spend additional funds in ways that were valued byvoters.

Currículo-Sem-Tempo: a (Re)Construção da Educação de Infância

O currículo é, indubitavelmente, o mentor da aprendizagem. Produzido pelos educadores de infância, é importante que, ao contextualizá-lo, reflitam, de forma crítica e construtiva, sobre que conhecimentos, importantes ou válidos, merecem fazer parte do currículo, e se é importante dar tempo às crianças para interiorizarem as aprendizagens. Assim, o trabalho começa por apresentar uma revisão literária sobre a essência dos conceitos aludidos, passando, de seguida, para uma reflexão sobre a (re)construção do currículo ancorado na proposta de um currículo-sem-tempo, por forma a dar tempo às crianças para construírem a sua identidade, subjetividade, interesses e aprendizagens.

Inter- and intra-individual variation of oxytocin secretion in oestrous mares exposed to stallions

The neuro-peptide hormone oxytocin regulates several reproductive mechanisms in mammals, such as uterine contractions during parturition and milk ejection in the lactating mammary gland. Oxytocin may also influence behavior and behavioral strategies, e.g. pair bonding, social recognition, maternal behavior, trust building, or anxiety. Teasing oestrous mares by a stallion provokes the release of oxytocin. We therefore tested whether such elevated oxytocin levels reveal possible mate preferences as determined in typical preference tests.

La lettera dellisole che ha trovato nuovamente el re di Spagna ([Reprod.]) / [Giuliano Dati]

Collection : Italian books before 1601 ; 103.1

(Re)configuração identitária das mulheres cujos maridos/companheiros emigraram: Uma análise a partir das mulheres de Pilão-Cão

Esta dissertação visa investigar a realidade das mulheres cujos maridos/companheiros emigraram em Pilão Cão de modo a compreender se as mudanças ocorridas a partir da saída dos seus cônjuges as levam a construir uma nova imagem de si e por conseguinte uma nova identidade. Para a concretização desse objectivo realizou-se uma pesquisa etnográfica junto dessas mulheres onde foram recolhidos os dados que retractam vários aspectos relacionados às suas experiências pessoais e familiares, concretamente os papéis desempenhados, os sentimentos experimentados, o controle social a que são sujeitas e sua relação com os próprios familiares e com os familiares do marido/companheiro. A análise dos dados mostrou que as modificações às quais foram sujeitas são percebidas de uma forma diferente por essas mulheres, dependendo da relação que mantém com os seus maridos/companheiros no estrangeiro. Entretanto ficou patente que em alguns casos assumiram mudanças e a construção de uma nova identidade e noutros casos houve apenas a alteração dos papéis de género.

Employee referrals and the inter-industry wage structure

This paper investigates the role of employee referrals in the labor market.Using an original data set, I find that industries that pay wage premia andhave characteristics associated with high-wage sectors rely mainly on employeereferrals to fill jobs. Moreover, unemployment rates are higher in industries which use employee referrals more extensively. This paper develops an equilibrium matching model which can explain these empirical regularities. Inthis model, the matching process sorts heterogeneous firms and workers into two distinct groups: referrals match "good" jobs to "good" workers, while formalmethods (e.g., newspaper ads and employment agencies) match less-attractive jobs to disadvantaged workers. Thus, well-connected workers who learn quickly aboutjob opportunities use referrals to jump job queues, while those who are less well placed in the labor market search for jobs through formal methods. The split of firms and workers between referrals and formal search is, however, not necessarily efficient. Congestion externalities in referral search imply that unemployment would be closer to the optimal rate if firms and workers 'at themargin' searched formally.

Quality assessment of cardiovascular magnetic resonance in the setting of the European CMR registry: description and validation of standardized criteria.

BACKGROUND: Cardiovascular magnetic resonance (CMR) has become an important diagnostic imaging modality in cardiovascular medicine. However, insufficient image quality may compromise its diagnostic accuracy. We aimed to describe and validate standardized criteria to evaluate a) cine steady-state free precession (SSFP), b) late gadolinium enhancement (LGE), and c) stress first-pass perfusion images. These criteria will serve for quality assessment in the setting of the Euro-CMR registry. METHODS: Thirty-five qualitative criteria were defined (scores 0-3) with lower scores indicating better image quality. In addition, quantitative parameters were measured yielding 2 additional quality criteria, i.e. signal-to-noise ratio (SNR) of non-infarcted myocardium (as a measure of correct signal nulling of healthy myocardium) for LGE and % signal increase during contrast medium first-pass for perfusion images. These qualitative and quantitative criteria were assessed in a total of 90 patients (60 patients scanned at our own institution at 1.5T (n=30) and 3T (n=30) and in 30 patients randomly chosen from the Euro-CMR registry examined at 1.5T). Analyses were performed by 2 SCMR level-3 experts, 1 trained study nurse, and 1 trained medical student. RESULTS: The global quality score was 6.7±4.6 (n=90, mean of 4 observers, maximum possible score 64), range 6.4-6.9 (p=0.76 between observers). It ranged from 4.0-4.3 for 1.5T (p=0.96 between observers), from 5.9-6.9 for 3T (p=0.33 between observers), and from 8.6-10.3 for the Euro-CMR cases (p=0.40 between observers). The inter- (n=4) and intra-observer (n=2) agreement for the global quality score, i.e. the percentage of assignments to the same quality tertile ranged from 80% to 88% and from 90% to 98%, respectively. The agreement for the quantitative assessment for LGE images (scores 0-2 for SNR <2, 2-5, >5, respectively) ranged from 78-84% for the entire population, and 70-93% at 1.5T, 64-88% at 3T, and 72-90% for the Euro-CMR cases. The agreement for perfusion images (scores 0-2 for %SI increase >200%, 100%-200%,<100%, respectively) ranged from 81-91% for the entire population, and 76-100% at 1.5T, 67-96% at 3T, and 62-90% for the Euro-CMR registry cases. The intra-class correlation coefficient for the global quality score was 0.83. CONCLUSIONS: The described criteria for the assessment of CMR image quality are robust with a good inter- and intra-observer agreement. Further research is needed to define the impact of image quality on the diagnostic and prognostic yield of CMR studies.

Do “Quarto de Casa” ao Bairro [Re]qualificação dos Bairros Precários da Cidade da Praia

A presente dissertação aborda um dos maiores desafios que os países em desenvolvimento enfrentam actualmente: o rápido crescimento dos bairros precários sem um planeamento prévio, que chegam a representar nestes países, de um terço a mais de metade do ambiente construído destas cidades. Considerando um território específico – a cidade da Praia, Cabo Verde – a investigação desenvolvida procura contribuir para a compreensão dos processos de formação e transformação dos assentamentos precários e ainda para o debate de soluções de reurbanização. A investigação procurou sistematizar um conjunto de conceitos e metodologias discutidos, actualmente, por diversos autores complementado com a experiência prática da cidade de Valparaíso, Chile, uma cidade construída praticamente sem um planeamento prévio. Estas duas vertentes contribuíram para a construção de um ponto de vista próprio que sustenta a crítica, a reflexão e as opções tomadas. Procura-se compreender e reflectir, através de um olhar crítico, sobre a situação urbana e arquitectónica da cidade da Praia actual, a sua origem e a expansão desde a fundação, a legislação e os instrumentos legais de planeamento. Pretende-se ainda, analisar as soluções propostas pelas entidades que intervêm nos assentamentos precários da cidade frente às tipologias de ocupação adoptadas pela população que não consegue aceder à oferta formal disponível. Priviligiase nesta análise o quarto de casa, a solução mais recorrente, que constitui a unidade mínima a partir da qual a habitação se expande. Estes factores contribuíram para a construção de uma metodologia de intervenção nos bairros precários da cidade da Praia, que se espera que possa ser mais um contributo que poderá complementar as soluções existentes e preencher algumas das lacunas identificadas. Com efeito esta tem como intuito favorecer uma maior aproximação das soluções à identidade, às expectativas e às necessidades da população envolvida. Esta metodologia procura identificar as oportunidades e lacunas, discutir os princípios conceptuais considerados mais pertinentes e reflectir a sua operacionalização a várias escalas e nas diferentes fases do processo.

Molecular basis of coagulation factor V deficiency caused by the R1698W inter-domain mutation.

Coagulation factor V (FV) deficiency is characterised by variable bleeding phenotypes and heterogeneous mutations. To add new insights into the FV genotype-phenotype relationship, we characterised the R1698W change in the A3 domain, at the poorly investigated interface with the A2 domain. The FV R1698W mutation was responsible for a markedly reduced expression level (10% of FV-WT) and specific activity in thrombin generation (0.39). Interestingly, the FVa1698W showed rapid activity decay upon activation due to increased dissociation rate between the heavy and light chains. The importance of the size and charge of the residue at position 1698 was investigated by three additional recombinant mutants, FVR1698A, FVR1698Q, and FVR1698E. FVR1698A and FVR1698Q expression (30 and 45% of FV-WT), specific activity (both 0.57) and stability were all reduced. Noticeably, FVR1698E showed normal activity and stability despite poor expression (10% of FV-WT). These data indicate the essential role of R1698 for normal biosynthetic process and support local flexibility for positively or negatively charged residues to produce stable and functional A3-A2 domain interactions. Their experimental alteration produces a gradient of FV defects, which help to interpret the wide spectrum of phenotypes in FV-deficient patients.

The re-introduction of oral entrance examinations at a translation studies department

Abstract

Cognitive Issues in Fingerprint Analysis: Inter- and Intra-Expert Consistency and the Effect of a "Target" Comparison

Deciding whether two fingerprint marks originate from the same source requires examination and comparison of their features. Many cognitive factors play a major role in such information processing. In this paper we examined the consistency (both between- and within-experts) in the analysis of latent marks, and whether the presence of a 'target' comparison print affects this analysis. Our findings showed that the context of a comparison print affected analysis of the latent mark, possibly influencing allocation of attention, visual search, and threshold for determining a 'signal'. We also found that even without the context of the comparison print there was still a lack of consistency in analysing latent marks. Not only was this reflected by inconsistency between different experts, but the same experts at different times were inconsistent with their own analysis. However, the characterization of these inconsistencies depends on the standard and definition of what constitutes inconsistent. Furthermore, these effects were not uniform; the lack of consistency varied across fingerprints and experts. We propose solutions to mediate variability in the analysis of friction ridge skin.