951 resultados para knowledge discovery


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Introduction: bronchial asthma is a chronic disease that affects a high percentage of adolescents, with a significant restriction of daily activities, and is a cause of school absenteeism. The relationships between adolescents and asthma disease in school were assessed, with a view to improving knowledge about the asthmatic adolescent. Methods: a survey was conducted in the Lisbon metropolitan area, covering urban (Lisbon) and rural (Lourinh˜a ) zones and including 1879 students and 81 teachers from the 7th to 9th high school years. The study groups were asthmatic students, their peers, and teachers. A self-administered questionnaire was applied to collect information. The results were compared with a reference group of 91 asthmatic students attending our Department of Immunoallergy-Hospital Dona Estefânia. Cotinine urinary measurements were made in a sample of asthmatics and a control group. Results: the prevalence of current asthma among students was 10%. Estimates of asthma annual burden among 7th to 9th year students from Lisbon and Lourinh˜a high schools included 4,307 days missed from school, 4,148 medical consultations and a minimum of 351 hospital emergency care and 80 hospital admissions. Exposure to passive smoking was not significantly different between asthmatic students and theirs peers. Cotinine urinary measurements did not discriminate between exposed and non-exposed individuals. Cigarette smoking was almost as common among adolescent asthmatics (5.4%) as it was in non-asthmatic subjects (6.7%). However, 55% of asthmatics mentioned active and passive smoking as an asthma exacerbating factor. Asthmatic students, theirs peers and teachers showed a deficient knowledge about asthma (mean group scores: 17.6; 14.2 and 17.7 of a possible 30), particularly in the areas related to asthma recognition and its management. Asthmatics attending our Allergy Department had the highest scores. All groups showed tolerance in the sense of a positive and understanding attitude toward a person with asthma. However, traditional beliefs about asthma disease (dependence, inferiority...) were confirmed. A positive correlation between knowledge levels and tolerance attitudes was found. Conclusion: in view of the dimension of the asthma problem in adolescence and its social and economic impact, it is justifiable to assess the need for the implementation of asthma education programs in schools in order to improve asthma management by the adolescents and their schools.

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Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do Grau de Mestre em Engenharia Electrotécnica e de Computadores

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This paper explores the relationship between the expatriates’ knowledge acquisition (KA) and their career development after an international assignment (IA). The purpose of this paper is to examine the role of expatriates in KA and transfer within International Portuguese multinational corporations. Furthermore, with this empirical study we try to analyse how the knowledge that is acquired and transferred translates into a basis for career development after the IA. This phenomenon has a special relevance in the Portuguese context, because this country is known a growing process of globalization in recent years. Furthermore, (a) there are no empirical studies concerning knowledge transfer and career development of repatriates from Portuguese companies; (b) little is known about the repatriates’ contributions to their home company after IA. This paper is one of the first to focus specifically on the repatriates’ role in KA and transfer from the host company to their Portuguese home company. A qualitative research methodology is used, specifically through an exploratory case study approach, which examines how knowledge management (KM) acquisition or transferring during IA are important for the repatriates’ career development in the Portuguese home company. Data were collected through semi-structured interviews to 42 Portuguese international assignees and 18 organizational representatives from nine Portuguese companies. Preliminary results show that KA and transfer made by Portuguese expatriates contributes directly to their career development. Moreover, evidence reveals that not all repatriates were promoted after their IA; rather some repatriates were even demoted after their IA. Furthermore, the results obtained suggest that the type of knowledge which acquired or transferred plays a central role in the career development after repatriation. According to these results, the paper discusses the major theoretical and practical implications. Suggestions for future research are also presented.

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ABSTRACT This study was conducted to assess mental health knowledge, attitude and practices among health care workers in Belize before and immediately after a competency based training program in mental health. A baseline Knowledge, Attitudes and Practices (KAP) survey was given to health personnel, mainly nurses, working primary and secondary care. The intervention was a 13-week face-to-face training course for health care professionals with the objective of increasing their competency in mental health and reducing stigma. After the training a post intervention KAP survey was conducted among the original respondents. 88 health care workers completed the baseline survey and 61 of those respondents completed the post-intervention questionnaire. The results showed that the level of knowledge of the participants had improved by the training intervention and that in general, the intervention was effective in correcting some misconceptions about mental illness and reducing stigmatizing attitudes among the participants.

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A crowdsourcing innovation intermediary performs mediation activities between companies that have a problem to solve or that seek a business opportunity, and a group of people motivated to present ideas based on their knowledge, experience and wisdom, taking advantage of technology sharing and collaboration emerging from Web2.0. As far as we know, most of the present intermediaries don´t have, yet, an integrated vision that combines the creation of value through community development, brokering and technology transfer. In this paper we present a proposal of a knowledge repository framework for crowdsourcing innovation that enables effective support and integration of the activities developed in the process of value creation (community building, brokering and technology transfer), modeled using ontology engineering methods.

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RESUMO A prática profissional docente é uma atividade complexa que pressupõe a capacidade de mobilização de pressupostos teóricos e legais, de saberes científicos, pedagógicos e didáticos, fruto de uma formação adequada à construção de cidadãos capazes de intervir ativamente na sociedade. Surgindo como requisito fundamental para o término do Mestrado em Ensino do 1.º e 2.º Ciclos do Ensino Básico e sendo parte integrante da Unidade Curricular de Integração Curricular: Prática Educativa e Relatório de Estágio, o presente documento pretende espelhar o percurso formativo da mestranda, revelando os pressupostos teóricos que orientaram a sua prática, assim como a descrição e reflexão sobre o trabalho realizado ao longo deste ano. Todo este trabalho decorreu em par pedagógico, possibilitando a construção partilhada de conhecimentos e uma visão mais próxima da realidade. O processo de formação sustentou-se não só na colaboração, mas também numa metodologia de investigação-ação, procurando agir de acordo com o importante ciclo inerente à profissão docente, ou seja, o ciclo de observação, planificação, reflexão e avaliação. Todo este processo de formação, incluindo a redação do presente relatório, contribui para o desenvolvimento pessoal e profissional da mestranda, estimulando a descoberta da identidade profissional docente. Este documento marca, então, o fim desta formação inicial, estando longe de ser o fim das aprendizagens e desafios que o futuro como docente reserva, sendo, por isso, o início de uma nova etapa e de novos caminhos a percorrer.

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Relatório EPE - Relatório de Estágio em Educação Pré-Escolar: Para aprender a ensinar é necessário passar por diversas etapas, assim sendo, o presente relatório é o culminar de um primeiro momento de estágio, do primeiro contacto com a profissão com todas as dinâmicas e especificidades de que dela fazem parte. Pretendendo-se ser um educador reflexivo e investigador, em que o desejo de saber o porquê daquilo que observa, o leva a descobrir novas coisas e a refletir sempre sobre elas, é fulcral que se conheçam alguns pressupostos teóricos que sirvam de suporte à prática a realizar. Desta forma, é feita uma contextualização teórica em que se aborda o papel do Educador de Infância, agente tão importante na educação das crianças, uma vez que educa os cidadãos de amanhã. Ao mesmo tempo, são ainda abordados alguns tópicos pertinentes relativamente à educação de infância, como a organização do ambiente educativo, a intencionalidade educativa, assim como modelos e perspetivas teóricas que fundamentam toda a prática desenvolvida. Com a realização deste relatório, inicia-se a construção do profissional reflexivo e investigador. Neste sentido, reflete-se acerca de toda ação pedagógica desenvolvida, assim como dos aspetos que se devem melhorar no futuro e que objetivos anteriormente definidos foram já alcançados. Na certeza de que o período de prática pedagógica referenciada foi o primeiro de muitos momentos de autodescoberta e realização pessoal, espera-se que o mesmo seja capaz de transparecer toda a experiência e enriquecimento para quem o lê. Relatório EPE - Relatório de Estágio em Educação Pré-Escolar:In order to learn how to teach, one needs to follow several stages, and on that path, the present report is the final step of a first stage in the trainee program, one that marked the first contact with the teaching profession and with all its dynamics and specifics. The aim is to be a reflexive educator and researcher, one that desires to understand the reason and motive of its object, one that is led to the discovery of new things and to a reflection on them. On that line, it is important to know some theoretical concepts to support the practice. With that goal in mind, this paper is a theoretical contextualization relating to the role of the infant teacher, a very important one, as it concerns the education of future citizens. At the same time, some relevant topics are addressed in what concerns the work of the infant teacher, such as the arrangement of the educational environment, the educational intentionality, and also theoretical models and perspectives, fundamental to the developed work. With this report begins the construction of the reflexive professional and researcher. In doing so, it is a reflection on several issues, namely, on all the pedagogical actions developed throughout the stage, on the features to improve in the future, and what previously defined goals were already achieved. Without a doubt, this stage of educational action is the first of several moments of self-discovery and personal achievement. Hopefully, this report will be able to reflect all the experience and to be an enriching experience to the reader.

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High-content analysis has revolutionized cancer drug discovery by identifying substances that alter the phenotype of a cell, which prevents tumor growth and metastasis. The high-resolution biofluorescence images from assays allow precise quantitative measures enabling the distinction of small molecules of a host cell from a tumor. In this work, we are particularly interested in the application of deep neural networks (DNNs), a cutting-edge machine learning method, to the classification of compounds in chemical mechanisms of action (MOAs). Compound classification has been performed using image-based profiling methods sometimes combined with feature reduction methods such as principal component analysis or factor analysis. In this article, we map the input features of each cell to a particular MOA class without using any treatment-level profiles or feature reduction methods. To the best of our knowledge, this is the first application of DNN in this domain, leveraging single-cell information. Furthermore, we use deep transfer learning (DTL) to alleviate the intensive and computational demanding effort of searching the huge parameter's space of a DNN. Results show that using this approach, we obtain a 30% speedup and a 2% accuracy improvement.

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The objective of the paper is to help to understand recent changes in the structure of R&D activities, by analyzing data on the expenditure of the business sector in research and development (R&D). The results are framed in an international context, through comparison with indicators from the most developed countries, divided by technological intensity and economic activity. The study reveals that the indicators of Portuguese R&D expenditure in the business sector are closely linked both to fiscal policy and to high foreign direct investment in knowledge-intensive industries. It also links these indicators to phenomena such as the abundance of skilled labor in pharmaceutical industries and the government intervention in some sectors of the economy (namely health and rail transportation).

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Urticaria, defined by the presence of wheals and/or angioedema,is a common condition in children, prompting parents to consult physicians. For its successful management, paediatric-specific features must be taken into account, regarding the identification of eliciting triggers and pharmacological therapy. This review systematically discusses the current best-available evidence on spontaneous acute and chronic urticaria as well as physical and other urticaria types in children. Potential underlying causes, namely infections, food and drug hypersensitivity, autoreactivity and autoimmune or other conditions, and eliciting stimuli are considered, with practical recommendations for specific diagnostic approaches. Second-generation antihistamines are the mainstay of pharmacological treatment aimed at relief of symptoms, which require dose adjustment for paediatric use. Other therapeutic interventions are also discussed. In addition, unmet needs are highlighted, aiming to promote research into the paediatric population, ultimately aiming at the effective management of childhood urticaria.

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Dissertação para obtenção do Grau de Mestre em Engenharia Biomédica

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Dissertation submitted in partial fulfillment of the requirements for the Degree of Master of Science in Geospatial Technologies.

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Dissertation submitted in partial fulfillment of the requirements for the Degree of Master of Science in Geospatial Technologies.

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The present study conducted a toxoplasmosis-related knowledge level survey with 400 pregnant and puerperal women attended in public health units in the municipality of Niterói, Rio de Janeiro. Only 111 (27.8%) women claimed to know about the disease. Most of them (n = 289; 72.2%) had never heard about toxoplasmosis nor knew how to prevent the infection by Toxoplasma gondii. A significant difference (p = 0.013) regarding the presence of anti-T. gondii IgG was observed between women who claimed to know about the disease and those who had never heard about it. These results highlight the importance of a systematic serological screening process for toxoplasmosis, as well as the importance of primary prevention by accurate information during prenatal care, an important Public Health action to be implemented.

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O sector do turismo é uma área francamente em crescimento em Portugal e que tem desenvolvido a sua divulgação e estratégia de marketing. Contudo, apenas se prende com indicadores de desempenho e de oferta instalada (número de quartos, hotéis, voos, estadias), deixando os indicadores estatísticos em segundo plano. De acordo com o “ Travel & tourism Competitiveness Report 2013”, do World Economic Forum, classifica Portugal em 72º lugar no que respeita à qualidade e cobertura da informação estatística, disponível para o sector do Turismo. Refira-se que Espanha ocupa o 3º lugar. Uma estratégia de mercado, sem base analítica, que sustente um quadro de orientações específico e objetivo, com relevante conhecimento dos mercados alvo, dificilmente é compreensível ou até mesmo materializável. A implementação de uma estrutura de Business Intelligence que permita a realização de um levantamento e tratamento de dados que possibilite relacionar e sustentar os resultados obtidos no sector do turismo revela-se fundamental e crucial, para que sejam criadas estratégias de mercado. Essas estratégias são realizadas a partir da informação dos turistas que nos visitam, e dos potenciais turistas, para que possam ser cativados no futuro. A análise das características e dos padrões comportamentais dos turistas permite definir perfis distintos e assim detetar as tendências de mercado, de forma a promover a oferta dos produtos e serviços mais adequados. O conhecimento obtido permite, por um lado criar e disponibilizar os produtos mais atrativos para oferecer aos turistas e por outro informá-los, de uma forma direcionada, da existência desses produtos. Assim, a associação de uma recomendação personalizada que, com base no conhecimento de perfis do turista proceda ao aconselhamento dos melhores produtos, revela-se como uma ferramenta essencial na captação e expansão de mercado.