901 resultados para Washington State Liquor Control Board.
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Bivalve mollusk shells are useful tools for multi-species and multi-proxy paleoenvironmental reconstructions with a high temporal and spatial resolution. Past environmental conditions can be reconstructed from shell growth and stable oxygen and carbon isotope ratios, which present an archive for temperature, freshwater fluxes and primary productivity. The purpose of this thesis is the reconstruction of Holocene climate and environmental variations in the North Pacific with a high spatial and temporal resolution using marine bivalve shells. This thesis focuses on several different Holocene time periods and multiple regions in the North Pacific, including: Japan, Alaska (AK), British Columbia (BC) and Washington State, which are affected by the monsoon, Pacific Decadal Oscillation (PDO) and El Niño/Southern Oscillation (ENSO). Such high-resolution proxy data from the marine realm of mid- and high-latitudes are still rare. Therefore, this study contributes to the optimization and verification of climate models. However, before using bivalves for environmental reconstructions and seasonality studies, life history traits must be well studied to temporally align and interpret the geochemical record. These calibration studies are essential to ascertain the usefulness of selected bivalve species as paleoclimate proxy archives. This work focuses on two bivalve species, the short-lived Saxidomus gigantea and the long-lived Panopea abrupta. Sclerochronology and oxygen isotope ratios of different shell layers of P. abrupta were studied in order to test the reliability of this species as a climate archive. The annual increments are clearly discernable in umbonal shell portions and the increments widths should be measured in these shell portions. A reliable reconstruction of paleotemperatures may only be achieved by exclusively sampling the outer shell layer of multiple contemporaneous specimens. Life history traits (e.g., timing of growth line formation, duration of the growing season and growth rates) and stable isotope ratios of recent S. gigantea from AK and BC were analyzed in detail. Furthermore, a growth-temperature model based on S. gigantea shells from Alaska was established, which provides a better understanding of the hydrological changes related to the Alaska Coastal Current (ACC). This approach allows the independent measurement of water temperature and salinity from variations in the width of lunar daily growth increments of S. gigantea. Temperature explains 70% of the variability in shell growth. The model was calibrated and tested with modern shells and then applied to archaeological specimens. The time period between 988 and 1447 cal yrs BP was characterized by colder (~1-2°C) and much drier (2-5 PSU) summers, and a likely much slower flowing ACC than at present. In contrast, the summers during the time interval of 599-1014 cal yrs BP were colder (up to 3°C) and fresher (1-2 PSU) than today. The Aleutian Low may have been stronger and the ACC was probably flowing faster during this time.
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Panel 5: Memories and Fantasies of Genocides Mark Hobbs, University of Winchester, United Kingdom: "Destroying Memory: The Attack on Holocaust Conscience and Memory in Britain 1942-2011" Download paper (login required) Kristen Dyck, Washington State University: "Hate Rock: White-Power Music in International Perspective" Download paper (login required) Audrey Mallet, Concordia University, Canada: “The Old Jewish Strangler and Other Ghost Stories: Poles’ Struggle to Come to Terms with the Holocaust” Download paper (login required) Tea Rozman-Clark, University of Nova Gorica, Slovenia: “Oral History: UN Peacekeepers and Local Population of the UN Safe Area Srebrenica” Download paper (login required) Chair: Kimberly Partee and Kathrin Haurand, Clark UniversityComment: Cecilie Felicia Stokholm Banke, Danish Institute for International Studies, Copenhagen
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It is said that the deprofessionalisation of social work and other welfare occupations reduces workers' professional discretion and autonomy, and thus their capacity to act in the best interests of their client. Without necessarily regarding the deprofessionalisation thesis as conclusive, this paper will ask how the state's control of the role and task of social workers impacts on their role-implicated obligations as professionals. If workers are reduced (as claimed) to the status of mere functionaries in systems they neither approve of nor control, does this exonerate them from bad outcomes or service failures? How should we view the dramatic increase in formal regulation now seen in the UK - as professionalisation or deprofessionalisation? The paper will argue that whatever the drift of policy, workers remain in some measure personally accountable. Service failures imply faults of practical reason that are partly attributable to the moral and intellectual character of professionals as individuals. It is therefore up to professionals, and their organisations, to attend to the improvement of professional character.
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Mayer H. Entrepreneurship in a hub-and-spoke industrial district: firm survey evidence from Seattle's technology industry, Regional Studies. The paper investigates entrepreneurial dynamics in a hub-and-spoke industrial district. Using data on the genealogy of high-technology firms in Seattle, Washington State, the study examines the ways in which entrepreneurial firms relate to their parent firms and the role of agglomeration economies. The results illustrate that entrepreneurship is an important vehicle for the diversification of such a district. When compared, hub-related spinoffs such as those founded by former Microsoft employees do not differ much from other start-ups. The differences between Microsoft spinoffs and start-ups are very limited; both diversify the regional economy by entering new markets when compared with their parents.
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UPTAKE AND METABOLISM OF 5’-AMP IN THE ERYTHROCYTE PLAY KEY ROLES IN THE 5’-AMP INDUCED MODEL OF DEEP HYPOMETABOLISM Publication No. ________ Isadora Susan Daniels, B.A. Supervisory Professor: Cheng Chi Lee, Ph.D. Mechanisms that initiate and control the natural hypometabolic states of mammals are poorly understood. The laboratory developed a model of deep hypometabolism (DH) initiated by uptake of 5’-adenosine monophosphate (5’-AMP) into erythrocytes. Mice enter DH when given a high dose of 5’-AMP and the body cools readily. Influx of 5’-AMP appears to inhibit thermoregulatory control. In a 15°C environment, mice injected with 5’-AMP (0.5 mg/gw) enter a Phase I response in which oxygen consumption (VO2) drops rapidly to 1/3rd of euthermic levels. The Phase I response appears independent of body temperature (Tb). This is followed by gradual body temperature decline that correlates with VO2 decline, called Phase II response. Within 90 minutes, mouse Tb approaches 15°C, and VO2 is 1/10th of normal. Mice can remain several hours in this state, before gradually and safely recovering. The DH state translates to other mammalian species. Our studies show uptake and metabolism of 5’-AMP in erythrocytes causes biochemical changes that initiate DH. Increased AMP shifts the adenylate equilibrium toward ADP formation, consequently decreasing intracellular ATP. In turn, glycolysis slows, indicated by increased glucose and decreased lactate. 2,3-bisphosphoglycerate levels rise, allosterically reducing oxygen affinity for hemoglobin, and deoxyhemoglobin rises. Less oxygen transport to tissues likely triggers the DH model. The major intracellular pathway for AMP catabolism is catalyzed by AMP deaminase (AMPD). Multiple AMPD isozymes are expressed in various tissues, but erythrocytes only have AMPD3. Mice lacking AMPD3 were created to study control of the DH model, specifically in erythrocytes. Telemetric measurements demonstrate lower Tb and difficulty maintaining Tb under moderate metabolic stress. A more dramatic response to lower dose of 5’-AMP suggests AMPD activity in the erythrocyte plays an important role in control of the DH model. Analysis of adenylates in erythrocyte lysate shows 3-fold higher levels of ATP and ADP but similar AMP levels to wild-type. Taken together, results indicate alterations in energy status of erythrocytes can induce a hypometabolic state. AMPD3 control of AMP catabolism is important in controlling the DH model. Genetically reducing AMP catabolism in erythrocytes causes a phenotype of lower Tb and compromised ability to maintain temperature homeostasis.
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Selbstkontrolle spielt in pädagogischen Kontexten oft eine entscheidende Rolle, beispielsweise wenn Lernende attraktiven Handlungsalternativen widerstehen müssen. Etliche Studien zeigen, dass die erfolgreiche Ausübung von Selbstkontrolle von der momentanen Verfügbarkeit an Selbstkontrollkraft abhängt. Zur Erfassung der momentanen Selbstkontrollkraft in deutschsprachigen Stichproben, wurde die State Self-Control Capacity Scale ins Deutsche adaptiert. In der vorliegenden Arbeit wird über fünf Teilstudien berichtet, in denen die psychometrische Güte dieser Skala überprüft wurde. Über alle Studien hinweg erwies sich die eindimensionale Skala als sehr reliabel (Cronbachs Alphas ≥ .93). Bezüglich ihrer Validität zeigten sich erwartete Zusammenhänge mit Validitätskriterien (z. B. Angst, Stress, am gegenwärtigen Tag bereits in Lehrveranstaltungen verbrachte Zeit); zusätzlich gelang die empirische Trennung von verschiedenen Stimmungsaspekten. Des Weiteren bildete die neue Skala (quasi-) experimentell im Labor und im Feld (Hochschule) induzierte Unterschiede in der Selbstkontrollkraft ab. Auch eine aus zehn Items bestehende Kurzskala erwies sich als hinreichend reliabel und valide.
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Growing scab-resistant apple cultivars on fully dwarfing rootstocks increases the feasibility for producing organically grown apples in the Midwest. However, in an organic orchard, fruit thinning to optimize crop load must be done by hand at a very high labor expense. The alternative is biennial bearing and inconsistent supply to meet consumer demands. Recently, sprays containing organicapproved materials such as liquid lime sulfur, fish, and various vegetable oils, salts, and kaolin have been tried alone or in combination for thinning apples with some degree of success. Lime sulfur alone or in combination with spray oil was recently labeled for use in Washington state orchards. This study was undertaken to evaluate the effectiveness of liquid lime sulfur alone and in combination with spray oil applied at various times during bloom on thinning three scab-resistant apple cultivars under Iowa conditions.
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Thirty-five samples from the drill core of the three Leg 163 sites (Sites 988, 989, and 990) off the southeast coast of Greenland were analyzed for 27 major, minor, and trace elements by X-ray fluorescence (XRF) and for 25 trace elements, including 14 rare-earth elements (REEs), by an inductively coupled plasma source mass spectrometer (ICP/MS). Sr- and Nd-isotope data are reported for seven samples and oxygen-isotope data are reported for 19 plagioclase separates. In addition, a reconnaissance survey of the composition of the main mineral phases, plagioclase, pyroxene, and oxides was determined on an electron microprobe to provide the basic information required for petrogenetic modeling. Olivine pseudomorphs are present in many of the samples, but in no case was an olivine grain found that was fresh enough to give a reliable analysis. The chemical and isotopic data recorded here were determined to provide a comparison with the larger data sets acquired by the Edinburgh, Copenhagen, and Leicester laboratories from both Legs 152 and 163 drill cores. This will permit a detailed comparison of the North Atlantic flood basalt province as a whole with the better known Columbia River, Deccan, and Karoo continental flood basalt provinces, for which substantial chemical data sets are already available at Washington State University.
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En los hospitales y residencias geriátricas de hoy en día es necesario que tengan un sistema asistencial paciente-enfermera. Este sistema debe ser capaz de controlar y gestionar cada una de las alarmas que se puedan generar en el menor tiempo posible y con la mayor eficacia. Para ello se ha diseñado una solución completa llamada ConnectCare. La arquitectura modular del sistema y la utilización de comunicación IP permiten adaptar el sistema a cada situación proporcionando soluciones específicas a medida. Este sistema se compone de un software llamado Buslogic que gestiona las alarmas en un servidor y de unos dispositivos llamados Fonet Control TCP/IP que posee una doble función: por una parte, sirve como dispositivo intercomunicador telefónico y por otra parte, sirve como dispositivo de gestión de alarmas y control de otros dispositivos externos. Como dispositivo intercomunicador telefónico, se integra en la red telefónica como un terminal de extensión analógica permitiendo la intercomunicación entre el paciente y el personal sanitario. Se hará una breve descripción de la parte intercomunicadora pero no es el objeto de este proyecto. En cambio, en la parte de control se hará más hincapié del diseño y su funcionamiento ya que sí es el objeto de este proyecto. La placa de control permite la recepción de señales provenientes de dispositivos de llamadas cableados, como son pulsadores asistenciales tipo “pera” o tiradores de baño. También es posible recibir señales de alerta de dispositivos no estrictamente asistenciales como detectores de humo o detectores de presencia. Además, permite controlar las luces de las habitaciones de los residentes y actuar sobre otros dispositivos externos. A continuación se mostrará un presupuesto para tener una idea del coste que supone. El presupuesto se divide en dos partes, la primera corresponde en el diseño de la placa de control y la segunda corresponde a la fabricación en serie de la misma. Después hablaremos sobre las conclusiones que hemos sacado tras la realización de este proyecto y sobre las posibles mejoras, terminando con una demostración del funcionamiento del equipo en la vida real. ABSTRACT. Nowadays, in hospitals and nursing homes it is required to have a patient-nurse care system. This system must be able to control and manage each one of the alarms, in the shortest possible time and with maximum efficiency. For this, we have designed a complete solution called ConnectCare. The system architecture is modular and the communication is by IP protocol. This allows the system to adapt to each situation and providing specific solutions. This system is composed by a software, called Buslogic, which it manages the alarms in the PC server and a hardware, called Fonet Control TCP / IP, which it has a dual role: the first role, it is a telephone intercom device and second role, it is a system alarm manager and it can control some external devices. As telephone intercom device, it is integrated into the telephone network and also it is an analog extension terminal allowing intercommunication between the patient and the health personnel. A short description of this intercommunication system will be made, because it is not the subject of this project. Otherwise, the control system will be described with more emphasis on the design and operation point of view, because this is the subject of this project. The control board allows the reception of signals from wired devices, such as pushbutton handset or bathroom pullcord. It is also possible to receive warning signals of non nurse call devices such as smoke detectors or motion detectors. Moreover, it allows to control the lights of the patients’ rooms and to act on other external devices. Then, a budget will be showed. The budget is divided into two parts, the first one is related with the design of the control board and the second one corresponds to the serial production of it. Then, it is discussed the conclusions of this project and the possible improvements, ending with a demonstration of the equipment in real life.
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Phosphorus pollution is a major concern in Illinois. Excessive amounts of phosphorus can be detrimental to water bodies. To help control phosphorus, the Illinois Pollution Control Board has proposed phosphorus limits on wastewater treatment facility discharges. If enacted, these limits will have negative impacts on the Springbrook Water Reclamation Center in Naperville, Illinois. To minimize these impacts, Naperville can utilize various non-point controls recommended in this paper to decrease the amount of phosphorus entering into the DuPage River and the Springbrook Water Reclamation Center. While these controls will not reduce levels low enough to totally satisfy limits on phosphorus discharges, they will significantly reduce the treatment costs Naperville will need to expend to meet them and be more environmentally effective.
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As threatened and endangered species, wild Pacific salmon are in peril. This paper discusses the differences of the five species of wild Pacific salmon. As salmon go through several stages of their lifecycles, they face a myriad of threats to their existence. Threats from humans in the form of hydropower dams, habitat destruction, harvesting issues, and hatcheries are explained. A draft recovery plan for salmon in the Puget Sound area of Washington State is used as a case study. Strengths and weaknesses of this plan are discussed. The paper then discusses the need for growth management laws supporting salmon habitat and a change in individual behaviors if wild Pacific salmon sustainability is to become a reality.
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