China 1:200,000 : Lishui Region, Zhejiang Sheng (Raster Image)

This layer is a georeferenced raster image of the Soviet Army topographic sheet map of the Lishui region, Zhejiang Sheng, China (map quadrangle number: H-50-XXXVI). It is from a series of Soviet Army topographic maps of China 1:200,000. Published in 1979, the source map was compiled from maps 1:100,000 published in 1977; corrected according to source material, 1973-1975. The image inside the map neatline is georeferenced to the surface of the earth and fit to the Pulkovo 1942 GK Zone 20N projection. Map collar information from the source map have been cropped and are not available as part of the raster image. China 1:200,000 topographic maps were prepared and printed by the Soviet Army General Headquarters, 1976-1991. China 1:200,000 maps are in Russian. Each source map in the series is printed in color. China 1:200,000 maps are typical topographic maps portraying both natural and manmade features. They show and name works of nature, such as mountains, valleys, lakes, rivers, vegetation, etc. They also identify the principal works and structures of humans, such as roads, railroads, paths, walls, boundaries, transmission lines, major buildings, etc. Relief is shown with standard contour intervals of 40 meters and/or spot heights.

Lowell and Belvidere Village, Massachusetts, 1832 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Plan of the town of Lowell and Belvidere Village, taken by measurement by Benjn. Mather. It was published by Pendleton's Lithography in 1832. The image inside the map neatline is georeferenced to the surface of the earth and fit to the Massachusetts State Plane Coordinate System, Mainland Zone (in Feet) (Fipszone 2001). All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, or other information associated with the principal map. This map shows features such as roads, railroads, existing and contemplated canals, other drainage, public buildings, residences, businesses and industries, buildings footprints, and more. Includes index to points of interest. This layer is part of a selection of digitally scanned and georeferenced historic maps of Massachusetts from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of regions, originators, ground condition dates (1755-1922), scales, and purposes. The digitized selection includes maps of: the state, Massachusetts counties, town surveys, coastal features, real property, parks, cemeteries, railroads, roads, public works projects, etc.

Newton, Massachusetts, 1831 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Map of the town of Newton, Mass., surveyed by E.F. Woodward & W.F. Ward. It was published by Annin, Smith, & Co.'s Lithogy. in Nov. 1831. Scale [ca. 1:20,660]. The image inside the map neatline is georeferenced to the surface of the earth and fit to the Massachusetts State Plane Coordinate System, Mainland Zone (in Feet) (Fipszone 2001). All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, or other information associated with the principal map. This map shows features such as roads, railroads, drainage, public buildings, schools, churches, cemeteries, industry locations (e.g. mills, factories, mines, etc.), private buildings with names of property owners, town boundaries and more. The map shows town boundaries as of 1831 and thus covers also portions of modern day Waltham and Boston. Manuscript annotations on the map show approximate locations of current town boundaries. Relief is shown by hachures. This layer is part of a selection of digitally scanned and georeferenced historic maps of Massachusetts from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of regions, originators, ground condition dates (1755-1922), scales, and purposes. The digitized selection includes maps of: the state, Massachusetts counties, town surveys, coastal features, real property, parks, cemeteries, railroads, roads, public works projects, etc.

Future of skills in Europe-Convergence or polarisation? CEPS Working Document No. 390, 27 February 2014

In this Working Paper, based on nearly 20 papers produced by the Centre for European Policy Studies, Slovak Governance Institute and the Conference Board Europe, we examine whether the current trends in the areas of education and skills are pushing the European Union, towards convergence or polarisation. We cover a wide range of questions related to this main issue. No easy answers, but several cross-cutting messages emerged from the research. We demonstrated that there is increasing complexity in what a ‘low-skilled’ person is and how well (or poorly) s/he fares in the labour market. There are undoubtedly powerful forces pushing for more polarisation, particularly in the labour market. Our research confirmed that early childhood education plays an important role, and it also appears to be increasingly uncontested as a policy prescription. However, the other frequently emphasised remedy to inequality – less selection in secondary education, particularly later division of children into separate tracks – is more problematic. Its effectiveness depends on the country in question and the target group, while education systems are extremely difficult to shift even on a long-term basis. A different, more-nuanced type of warning to policy-makers is delivered in our research on returns to higher education by field of study, which showed hidden rationality in how students choose their major.

The invisible hand... of the Kremlin. Capitalism 'a la russe'. OSW Point of View, February 2007

This study describes the two main economic processes observed in Russia during President Vladimir Putin's second term; renationalisation, and the concentration of economic assets. As a result of these processes, the share of state-owned property has increased and the position of the state in the economy has strengthened. According to the authorities, the wide-range renationalisation of the assets and the construction of superholdings based on the state enterprises are intended to boost Russia's potential and stimulate the development of the whole economy. However, in practice the current ruling elite are using these superholdings to strengthen Russia's position on the international arena and to promote their vested interests.

The Weakness of Post-Communist Civil Society Reassessed. CES Papers - Open Forum #11, 2012

During the last two decades, scholars from a variety of disciplines have argued that civil society is structurally deficient in post-communist countries. Yet why have the seemingly strong, active and mobilized civic movements of the transition period become so weak after democracy was established? And why have there been diverging political trajectories across the post-communist space if civil society structures were universally weak? This paper uses a wide range of data from various available sources to show that civil societies in Central and Eastern European countries are not as feeble as is commonly assumed. Some post-communist countries possess vigorous public spheres, and active civil society organizations strongly connected to transnational civic networks able to shape domestic policies. Following the calls by Anheier (2004) and Bernhard and Karakoç (2007) we adopt a multidimensional approach to the measurement of civil society. In a series of cross-section timeseries models, we show that our broader measures of civic and social institutions are able to predict the diverging transition paths among post-communist regimes, and in particular the growing gap between democratic East Central Europe and the increasingly authoritarian post-Soviet space.

Can group exercise programs improve health outcomes in pregnant women? A systematic review

Current scientific evidence supports the recommendation to initiate or continue the practice of physical exercise in healthy pregnant women. Group exercise programs have positive effects in improving health and well-being, as well as social support. In order to understand the scientific evidence in this field, and the outcomes in maternal health, it has generated wide interest in exploring the studies carried out with more relevant group exercise programs. The aim of this systematic review was to evaluate the available evidence on the effectiveness of group exercise programs in improving women’s and newborns health outcomes during pregnancy. Three databases were used to conduct literature searches and strict inclusion and exclusion criteria were employed. Seventeen studies were selected for analysis. All studies were randomized control trials conducted with pregnant women that evaluated the effect of group exercise programs on the health outcomes of mother and newborn. Most studies followed a supervised structured exercise program including a main aerobic part, resistance training, pelvic floor training and stretching and relaxation sections. The significant effects of the programs are related with improved maternal perception of health status, lower maternal weight gain, improved levels of maternal glucose tolerance, improved aerobic fitness and muscular strength, lower frequency of urinary incontinence, improved sick leave due to lumbopelvic pain, fewer cesarean and instrumental deliveries, higher newborn Apgar score and faster postpartum recovery. Exercise and health professionals should advise pregnant women that aerobic group exercise during pregnancy improves a wide range of health outcomes for the women and newborn

The Moldable Inspector

Object inspectors are an essential category of tools that allow developers to comprehend the run-time of object-oriented systems. Traditional object inspectors favor a generic view that focuses on the low-level details of the state of single objects. Based on 16 interviews with software developers and a follow-up survey with 62 respondents we identified a need for object inspectors that support different high-level ways to visualize and explore objects, depending on both the object and the current developer need. We propose the Moldable Inspector, a novel inspector model that enables developers to adapt the inspection workflow to suit their immediate needs by making the inspection context explicit, providing multiple interchangeable domain-specific views for each object, and supporting a workflow that groups together multiple levels of connected objects. We show that the Moldable Inspector can address multiple kinds of development needs involving a wide range of objects.

Organic geochemistry on sediment profiles from the Arctic Ocean

During the ARCTIC '91-Expedition with RV 'Polarstern', several Multicorer and Kastenlot-cores were recovered along a profile crossing the eastern part of the Arctic Ocean. The investigated cores consist mainly of clayey-silty sediments, and some units with a higher sand content. In this thesis, detailed sedimentological and organic-geochemical investigations were performed. In part, the near surface sediments were AMS-14C dated making it possible to Interpret the results of the organic-geochemical investigations in terms of climatic changes (isotopic stage 2 to the Holocene). The more or less absence of foraminifers within the long cores prevented the development of an oxygen isotope stratigraphy. Only the results of core PS2174-5 from the Amundsen-Basin could be discussed in terms of the climatic change that could be dated back to oxygen isotope stage 7. Detailed organic-geochemical investigations in the central Arctic Ocean are rare. Therefore, several different organic-geochemical methods were used to obtain a wide range of data for the Interpretation of the organic matter. The high organic carbon content of the surface sediments is derived from a high input of terrigenous organic matter. The terrigenous organic material is most likely entrained within the sea-ice On the Siberian shelves and released during ice-drift over the Arctic Ocean. Other factors such as iceberg-transport and turbidites are also responsible for the high input of terrigenous organic matter. Due to the more or less closed sea-ice Cover, the Arctic Ocean is known as a low productivity system. A model shows, that only 2 % of the organic matter in central Arctic Ocean sediments is of a marine origin. The influence of the West-Spitsbergen current increases the marine organic matter content to 16 %. Short chain n-alkanes (C17 and C19) can be used as a marker of marine productivity in the Arctic Ocean. Higher contents of short chain n-alkanes exist in surface sediments of the Lomonosov-Ridge and the Makarov-Basin, indicating a higher marine productivity caused by a reduced sea-ice Cover. The Beaufort-Gyre and Transpolar-Drift drift Patterns could be responsible for the lower sea-ice distribution in this region. The sediments of Stage 2 and Stage 3 in this region are also dominated by a higher content of short chain-nalkanes indicating a comparable ice-drift Pattern during that time. The content and composition of organic carbon in the sediments of core PS2174-5 reflect glaciallinterglacial changes. Interglacial stages 7 and 5e show a low organic carbon content (C 0,5 %) and, as indicated by high hydrogen-indices, low CIN-ratios, higher content of n-alkanes (C17 and C19) and a higher opal content, a higher marine productivity. In the Holocene, a high content of foraminifers, coccoliths, ostracodes, and sponge spicules indicate higher surface-water productivity. Nevertheless, the low hydrogenindices reveal a high content of terrigenous organic matter. Therefore, the Holocene seems to be different from interglacials 7 and 5e. During the glacial periods (stages 6, upper 5, and 4), TOC-values are significantly higher (0.7 to 1.3 %). In addition, low hydrogen-indices, high CIN-ratios, low short chain n-alkanes and opal contents provide evidence for a higher input of terrigenous organic matter and reduced marine productivity. The high lignin content in core sections with high TOC-contents, substantiates the high input of terrigenous organic matter. Changes in the content and composition of the organic carbon is believed to vary with the fluctuations in sea-level and sea-ice coverage.

In vivo gene expression: DNA electrotransfer

The use of electric pulses to deliver therapeutic molecules to tissues and organs in vivo is a rapidly growing field of research. Electrotransfer can be used to deliver a wide range of potentially therapeutic agents, including drugs, proteins, oligonucleotides, RNA and DNA. Optimization of this approach depends upon a number of parameters such as target organ accessibility, cell turnover, microelectrode design, electric pulsing protocols and the physiological response to the therapeutic agent. Many organs have been successfully transfected by electroporation, including skin, liver, skeletal and cardiac muscle, male and female germ cells, artery, gut, kidney, retinal ganglion cells, cornea, spinal cord, joint synovium and brain. Electrotransfer technology is relevant in a variety of research and clinical settings including cancer therapy, modulation of pathogenic immune reactions, delivery of therapeutic proteins and drugs, and the identification of drug targets by the modulation of normal gene expression. This, together with the capacity to deliver very large DNA constructs, greatly expands the research and clinical applications of in vivo DNA electrotransfer.

A common oscillator for perceptual rivalries?

Perceptual rivalry is an oscillation of conscious experience that takes place despite univarying, if ambiguous, sensory input. Much current interest is focused on the controversy over the neural site of binocular rivalry, a variety of perceptual rivalry for which a number of different cortical regions have been implicated. Debate continues over the relative role of higher levels of processing compared with primary visual cortex and the suggestion that different forms of rivalry involve different cortical areas. Here we show that the temporal pattern of disappearance and reappearance in motion-induced blindness (MIB) (Bonneh et al, 2001 Nature 411 798-801) is highly correlated with the pattern of oscillation reported during binocular rivalry in the same individual. This correlation holds over a wide range of inter-individual variation. Temporal similarity in the two phenomena was strikingly confirmed by the effects of the hallucinogen LSD, which produced the same, extraordinary, pattern of increased rhythmicity in both kinds of perceptual oscillation. Furthermore, MIB demonstrates the two properties previously considered characteristic of binocular rivalry. Namely the distribution of dominance periods can be approximated by a gamma distribution and, in line with Levelt's second proposition of binocular rivalry, predominance of one perceptual phase can be increased through a reduction in the predominance time of the opposing phase. We conclude that (i) MIB is a form of perceptual rivalry, and (ii) there may be a common oscillator responsible for timing aspects of all forms of perceptual rivalry.

Principles of Australian public law

In this relatively short book, David Clark sets out to fill what he perceives to be a gap in the presently available writing on Australian public law by achieving two distinct objectives. The first is to remedy 'one of the oddest limitations of current public law writing in Australia' by detailing the history and operation of the state and territory constitutions as well as their philosophical underpinnings. The other is to explore certain areas of federal public law, such as the laws applicable to the constitution and operation of the Commonwealth Parliament and non-judicial bodies such as the Ombudsman, which are often not dealt with in leading constitutional and administrative law texts. It is acknowledged by the author that attempting to cover such a wide range of topics is a 'high-wire act'. Fortunately, apart from one slight stumble, Clark manages to keep his balance and has produced a useful précis of a number of the institutions and concepts that are fundamental to the orderly functioning of Australian society.

Physical enhancement of transdermal drug application: is delivery technology keeping up with pharmaceutical development?

Advances in molecular biology have given us a wide range of protein and peptide-based drugs that are unsuitable for oral delivery because of their high degree of first-pass metabolism. Though parenteral delivery is the obvious answer, for the successful development of commercial chronic and self-administration usage formulations it is not the ideal choice. Transdermal delivery is emerging as the biggest application target for these agents, however, the skin is extremely efficient at keeping out such large molecular weight compounds and therapeutic levels are never going to be realistically achieved by passive absorption. Physical enhancement mechanisms including: iontophoresis, electroporation, ultrasound, photomechanical waves, microneedles and jet-propelled particles are emerging as solutions to this topical delivery dilemma. Adding proteins and peptides to the list of other large molecular weight drugs with insufficient passive transdermal fluxes to be therapeutically useful, we have a collection of pharmacological agents waiting for efficient delivery methods to be introduced. This article reviews the current state of physical transdermal delivery technology, assesses the pros and cons of each technique and summarises the evidence-base of their drug delivery capabilities.

Effect of environment and genotype on bread-making quality of spring-sown spring wheat cultivars in China

Improvement of end-use quality in bread wheat depends on a thorough understanding of current wheat quality and the influences of genotype (G), environment (E), and genotype by environment interaction (G x E) on quality traits. Thirty-nine spring-sown spring wheat (SSSW) cultivars and advanced lines from China were grown in four agro-ecological zones comprising seven locations during the 1998 and 1999 cropping seasons. Data on 12 major bread-making quality traits were used to investigate the effect of G, E, and G x E on these traits. Wide range variability for protein quantity and quality, starch quality parameters and milling quality in Chinese SSSW was observed. Genotype and environment were found to significantly influence all quality parameters as major effects. Kernel hardness, flour yield, Zeleny sedimentation value and mixograph properties were mainly influenced by the genetic variance components, while thousand kernel weight, test weight, and falling number were mostly influenced by the environmental variance components. Genotype, environment, and their interaction had important effects on test weight, mixing development time and RVA parameters. Cultivars originating from Zone VI (northeast) generally expressed high kernel hardness, good starch quality, but poor milling and medium to weak mixograph performance; those from Zone VII (north) medium to good gluten and starch quality, but low milling quality; those from Zone VIII (central northwest) medium milling and starch quality, and medium to strong mixograph performance; those from Zone IX (western/southwestern Qinghai-Tibetan Plateau) medium milling quality, but poor gluten strength and starch parameters; and those from Zone X (northwest) high milling quality, strong mixograph properties, but low protein content. Samples from Harbin are characterized by good gluten and starch quality, but medium to poor milling quality; those from Hongxinglong by strong mixograph properties, medium to high milling quality, but medium to poor starch quality and medium to low protein content; those from Hohhot by good gluten but poor milling quality; those from Linhe by weak gluten quality, medium to poor milling quality; those from Lanzhou by poor bread-making and starch quality; those from Yongning by acceptable bread-making and starch quality and good milling quality; and those from Urumqi by good milling quality, medium gluten quality and good starch pasting parameters. Our findings suggest that Chinese SSSW quality could be greatly enhanced through genetic improvement for targeted well-characterized production environments.

Genetic study of alcoholism and novel gene expression in the alcoholic brain

Alcohol dependence may result from neuroadaptation involving alteration of gene expression after long-term alcohol exposure. The systematic study of gene expression profiles of the human alcoholic brain was initiated using the method of polymerase chain reaction (PCR)-differential display and was followed by DNA microarray. To date, more than 100 alcohol-responsive genes have been identified from the frontal cortex, motor cortex and nucleus accumbens of the human brain. These genes have a wide range of functions in the brain and indicate diverse actions of alcohol on neuronal function. This review discusses the current information on the genetic basis of alcoholism and the induction and characterization of these alcohol-responsive genes.