935 resultados para Six, Jan, 1857-1926


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Estudio de muestras recolectadas con el BIONESS a varias profundidades en trece estaciones.

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Exploratory and confirmatory factor analyses reported in the French technical manual of the WISC-IV provides evidence supporting a structure with four indices: Verbal Comprehension (VCI), Perceptual Reasoning (PRI), Working Memory (WMI), and Processing Speed (PSI). Although the WISC-IV is more attuned to contemporary theory, it is still not in total accordance with the dominant theory: the Cattell-Horn-Carroll (CHC) theory of cognitive ability. This study was designed to determine whether the French WISC-IV is better described with the four-factor solution or whether an alternative model based on the CHC theory is more appropriate. The intercorrelations matrix reported in the French technical manual was submitted to confirmatory factor analysis. A comparison of competing models suggests that a model based on the CHC theory fits the data better than the current WISC-IV structure. It appears that the French WISC-IV in fact measures six factors: crystallized intelligence (Gc), fluid intelligence (Gf), short-term memory (Gsm), processing speed (Gs), quantitative knowledge (Gq), and visual processing (Gv). We recommend that clinicians interpret the subtests of the French WISC-IV in relation to this CHC model in addition to the four indices.

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Common variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans. To identify additional loci, we conducted meta-analysis of 15 genome-wide association studies for BMI (n > 32,000) and followed up top signals in 14 additional cohorts (n > 59,000). We strongly confirm FTO and MC4R and identify six additional loci (P < 5 x 10(-8)): TMEM18, KCTD15, GNPDA2, SH2B1, MTCH2 and NEGR1 (where a 45-kb deletion polymorphism is a candidate causal variant). Several of the likely causal genes are highly expressed or known to act in the central nervous system (CNS), emphasizing, as in rare monogenic forms of obesity, the role of the CNS in predisposition to obesity.

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En tête de cette chronique est une table, qui occupe les feuillets 1 à 5. Puis vient (fol. 6) une espèce de prologue en vers intitulé : « L'exorde de ce present livre » dont le premier vers est : « Affin que tous les faictz de nostre temps ... ». Le texte en prose débute (fol. 7) par : « La descripcion des oeuvres recommandables et commemorables gestes de très cristien roy de France Loys doziesme de ce nom, redigée en escript et mise en lumière par moy frère Jehan d'Auton, de l'ordre Sainct Benoist, historiographe du roy nostred. souverain seigneur. Après avoir par volumes abregez ostencion faicte des actes gallicanes et ultransmontaines choses encommancées à la fin de l'an mille quatre cens quatre vingts dix huyt et icelles continuées ... » et finit (fol. 230) par : « ... et puys très devotement celebra la joyeuse feste de Pasques, sur laquelle mectray paille à mon escript, jucques à temps, en faisant fin au recit de ce present historial volume contenant les faictz de France de l'an mille cincq cens et ung continuant jucques à l'an mille cincq cens et six ».

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Référence bibliographique : Rol, 59644