Relação entre carga parasitária de cães naturalmente acometidos por leishmaniose visceral e infectividade para Lutzomyia longipalpis: Lilian Aparecida Colebrusco Rodas. -

Pós-graduação em Ciência Animal - FMVA

Relação entre presença de anticorpos anti-leishmania spp. e carga parasitária em sangue de cães de área endêmica para leishmaniose visceral

Pós-graduação em Ciência Animal - FMVA

Imunofenótipos de linfócitos T no sangue e no liquor de cães com leishmaniose visceral: correlação com as lesões encefálicas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Infecção de Lutzomyia longipalpis por leishmania spp. em área urbana endêmica para leishmaniose visceral no Estado de São Paulo, Brasil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação das lesões encefálicas e fenotipagem de linfócitos T e células dentríticas em linfócitos de cães com leishmaniose visceral

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Serological detection of Toxoplasma gondii, Leishmania infantum and Neospora caninum in cats from an area endemic for leishmaniasis in Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Orientação sobre posse responsável em uma área endêmica para leishmaniose visceral canina

The purpose of this work was to provide guidance to householders in the responsible care of their pets, in a region where canine visceral leishmaniasis is endemic. Questionnaires on responsible ownership and the control of this disease were completed by owners of dogs and cats in the city of Araçatuba, São Paulo State, Brazil, in order to evaluate their level of knowledge. Based on the identified deficiencies, the project team provided the owners of the pets with individual guidance at home, focusing on the most critical issues. Concerning nutrition, 70.45% (62/88) of owners provided pet food only, 27.28% (24/88) administered a mixed diet, and 2.27% (2/88) provided homemade food. Additionally, 78.41% (69/88) did not permit the consumption of raw meat, rare meat, or bones. 9.09% (8/88) of owners allowed their pets to wander the neighborhood alone. Among dogs, 14.77% (13/88) had never been clinically tested by a qualified professional, and 6.82% (6/88) and 15.91% (14/88) had never received any kind of vaccine or vermifuge, respectively. In relation to population control, only 20.45% (18/88) of the dogs had been sterilized. It was also observed that 25% (22/88) of owners had already had canine visceral leishmaniasis seropositive dogs in their homes. 54.55% (12/22) of these owners had referred their pets to veterinary clinics for euthanasia, 22.73% (5/22) had used the services of the city’s animal disease control center, and 18.18% (4/22) had paid for private treatment. Nevertheless, 35.23% (31/88) of the dogs had never been submitted to tests for infection diagnosis. From the results obtained, it could be inferred that the individuals who participated in this study were poorly informed concerning basic pet care, demonstrating a need to implement community awareness campaigns for the responsible ownership of pets.

Programa de conscientização de idosos sobre posse responsável de animais de estimação em bairro periférico do município de Araçatuba, SP

Currently, responsible ownership of pets has been widely discussed. In the past, they were brought to our society and it is our duty nowadays to establish this relationship between man and animal. This study aimed at evaluating the level of knowledge of elderly dog owners about responsible ownership with emphasis on control of canine visceral leishmaniasis and at the same time make them aware of the precautions to be taken. An individual questionnaire on the subject was applied to 68 elderly people. They all belong to Nossa Senhora Aparecida Village, located on the suburb of Araçatuba-SP. Along with the interview, veterinary students advised them on the control of canine visceral leishmaniasis, the importance of sterilization in cats and dogs and the responsible ownership, with distribution of informative leaflets. Fecal samples from dogs were collected by the owners and they were sent to the Laboratory of Parasitology and Parasitic Diseases at Odontology Faculty at Araçatuba UNESP to be processed through the Willis-Mollay technique. Anthelmintic were acquired in the project and donated for the treatment of animals tested positive. 56.25% (63/112) out of the total number of dogs examined were females, aged between one and ten years. Only 32.14% (36/112) had access to the streets, 90.18% (101/112) were not castrated and 58% (65/112) were mixed breed (SRD). Among the owners, 88.24% (60/68) did not know what zoonosis is and 14.71% (10/68) were not aware what leishmaniasis is. Regarding the researched animals, 62.50% (70/112) had ectoparasites (fleas and ticks). It was also observed that 67.86% (76/112) of dogs had been dewormed, but in 59.82% (36/112) of cases, the intervals between these processes were irregular. For females, 85.71% (54/63) had no prevention heat and it was noted that 19.51% (8 / 41) had already given birth, had dystocia. With these data we can confirm the lack of information by these elderly and the need to establish community awareness and continued programs.

Clinical and epidemiological aspects of feline leishmaniasis in Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Leishmaniose visceral no Brasil

Visceral leishmaniasis (VL) is among the most important vector-borne diseases that occur in Brazil, mainly due to its zoonotic nature. It is currently present in almost all Brazilian territory, and its control is a challenge both for veterinarians and for public health officials. The etiologic agent is Leishmania infantum (syn chagasi), and the main vector in Brazil is Lutzomyia longipalpis. Of all animals identified as reservoirs of VL, the dog is considered the most important domestic reservoir. Although the disease has already been identified in cats, the epidemiological role of this animal species is still unclear. This article presents a brief review of the epidemiological situation of the disease, its mode of transmission, clinical features in dogs and cats as well as possible risk factors associated with the occurrence of the disease in Brazil.

Leucograma e metabolismo oxidativo dos neutrófilos de cães com leishmaniose visceral antes e após o tratamento com Antimoniato de Meglumina e Alopurinol

Leukogram and neutrophil oxidative metabolism from dogs with visceral leishmaniasis (VL) were compared before and after treatment with meglumine antimoniate (AM) and with an association of meglumine antimoniate and allopurinol (AMA). The results obtained demonstrated that neutrophils of dogs with VL do not lose their capacity of reducing NBT and that oxidative metabolism has been more active in the majority of the cases. After treatment with AM and AMA, dogs with VL presented a redution of neutrophils oxidative metabolism, suggesting that this decrease was related with the decrease in the number of parasites and a probable inhibitor effect of these drugs on neutrophils oxidative metabolism.

Perfil de citocinas do padrão Th1, Th2, Th17 e o estado redox de indivíduos com leishmaniose visceral pré e pós tratamento

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Ocorrência da leishmaniose visceral em cães e gatos em abrigos de animais de Ilha Solteira, SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Leishmaniose visceral e o sistema nervoso central: inflamação nas infecções natural canina e experimental em camundongos: Guilherme Dias de Melo. -

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relação da expressão do tlr-2, da enzima iNOS, das citocinas IL-10, TNF-α e TGF-β com a carga parasitária da pele de cães naturalmente acometidos por leishmaniose visceral: Dandara Camila Morais Pereira. -

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)