Memória, envelhecimento e qualidade de vida: a perspectiva da psicologia cognitiva

The concern with aging has increased in recent decades throughout the world, before the gradual increase in life expectancy of the population. Researchers have been developing a diverse in nature, in order to subsidize the activities of professionals in the field of Gerontology to promote autonomy, preservation of cognitive functions and thus contribute to healthy aging. This article presents a review of the literature on memory and aging from the perspective of cognitive psychology. The bibliography contains studies focusing on different subjects, in this sense. A significant number of works have been undertaken in order to investigate mechanisms and benefits of training on memory in healthy elderly and / or cognitive improvement. A concept that deserves attention in such studies is the study of aspects of meta-memory. However, there are still relatively few controlled studies on the subject.

Influência da adição de nanopartículas sobre a dureza, resistência à ruptura e deformação permanente de silicone facial submetido ao envelhecimento acelerado

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da eficácia e citotoxicidade de filme e sistema emulsionado contendo ácido cafeico

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Desempenho fisiológico e superação de dormência em sementes de Brachiaria brizantha submetidas a tratamento químico e envelhecimento artificial

The use of seeds of B. brizantha has increased, however, the physiological quality of seeds available to the producer is still a limiting factor for a good performance culture. The objective of this study was to evaluate the effects caused by chemical scarification, different periods of aging and priming on physiological quality and overcoming seed dormancy B. brizantha cv. MG-5 Victory. The seeds were subjected to chemical scarification-H2SO4 ( presence and absence), artificial aging periods ( zero, 24, 48, 72, 96, 120, 144 and 168 hours) at 41 degrees C and priming using the 0,2 KNO3 % ( presence and absence) for two hours at 25 degrees C, creating a completely randomized design in factorial 2x8x2, with four repetitions. The seeds were evaluated by testing germination and vigor. Chemical scarification is an effective method for breaking dormancy, but decreases the physiological seed. Overcoming seed dormancy B. brizantha occurs with the use of artificial aging for non-scarified and scarified seeds. Priming generally has no effect on the physiological quality and overcoming seed dormancy B. brizantha, however, it provides less loss of cellular constituents.

Estudo do envelhecimento da liga AA 7075 encruada

Aluminum alloys are widely used in industry, because they combine different mechanical properties according to the alloying elements used in addition to thermal and mechanical treatments performed, resulting in materials with good weight/resistance relation. The 7XXX series alloys are worked heat treatable alloys commonly used in the aerospace industry, especially due to their high mechanical properties obtained after aging heat treatment, which increases the interest around 7075 alloy. Some studies with alloys which can be aged show that it is possible that cold word processes affect the results of aging. Thus, this study was intended to verify the influence of the aging process of AA 7075 alloy. There were three routes of aging with specimens previously treated thermally. In the first route T6 treatment was performed with a annealed specimen and other in solid solution. The second was the natural aging in a annealed specimen. In the last route was done aging by steps with a annealed specimen and other in solid solution with the intention to reduce the effects of natural aging. The results show that the routes 1 and 3 had similar hardness for all the samples, showing that the validity of Route 3 as an alternative and also the hardening did not affect the hardness at the end of the process, significantly reducing the time required for the highest hardness. Finally, natural aging was less effective in increasing hardness

Comparação da aptidão física em idosos submetidos a diferentes intervenções de exercício físico

Introduction: The elderly population has increased, and the aging process is responsible for physical and metabolic changes in the body. For the elderly remain independent, with a better quality of life, preventing and treating diseases responsible for this increased of mortality should remain physically active. Objective: To investigate the influence of two types of exercise intervention on physical fitness and physical activity levels in older practitioners of Rio Claro-SP. Method: The study included 18 older adults with mean age 65.8 years (± 2.88) divided into two groups, Program in Physical Exercises Health Unit (PEFUS, n = 9) and Adapted Volleyball (n = 9). Classes of PEFUS were held twice a week lasting 60 min with strength, aerobic endurance, agility, coordination and balance exercises. Classes of Volleyball Adapted were performed 2 times per week lasting 120 minutes, divided into volleyball fundamental exercises and game. For evaluation of physical skills (strength, agility, coordination and flexibility), was performed the AAHPERD test battery. All participants were assessed at the baseline and after 3 months of interventions. The statistical analysis used was the repeated measures ANOVA, through the SPSS version 17.0 and significance level p <0.05. Result: After the interventions there was an increase of leisure time from 362.2 ± 214.9 min / week and 16.7 ± 28.3 min / week to 541.7 ± 137.2 and 44.4 ± 44.8 min / week to Adapted Volleyball and PEFUS, respectively. The variable coordination showed significant improvements after the interventions, decreasing from 12.1 ± 0.7 to 10.8 ± 0.5 sec for Volleyball Adapted and from 14.8 ± 0.9 to 12.1 ± 0, 9 sec for PEFUS (p <0.05). For the variable strength it was observed a group-moment interaction (p <0.05). Conclusion: The interventions showed positive results... (Complete abstract click electronic access below)

Comportamento de indivíduos com doença de Parkinson no levantar da cadeira e no início da marcha: relações com o envelhecimento

Large motor dysfunctions are observed in older adults with the age advance. Parkinson’s disease (PD) patients have motor deficits to perform daily living activities. To raise from a chair, a daily task necessary to live independently, requires both large muscle recruitment and large joint range of motion to achieve the vertical position safely. Normally, we initiate gait after raise from a chair. The aim of this study was to analyze the PD patients’ behavior when rising from a chair and initiating gait and to compare it according to the age advance. In order to do that, 23 PD patients (66.61±7.64 years old) were distributed in three age groups: Young group, between 51 and 60 years of age (n=7); intermediary group, between 61 and 70 years of age (n=7); and elderly group, over 70 years of age (n=9). There were no statistical differences among groups either for the disease evolution stage or for it compromising. The task was to stand from a chair and to initiate gait forward in three attempts. The dependent variables were: spatial and temporal (first step length and duration, and stride length, duration and velocity) and angular (flexion and extension of head, shoulder, hip, knee, and ankle). The motion of standing from a chair was divided in two phases. The data was statistically treated by means of Analyses of Variance with group as the only factor. The Scheffé’s post hoc test was used to localize differences among groups and the significance level was adjusted to p≤0.017. There were statistical differences for stride...(Complete abstract click electronic access below)

Estudo morfológico do fígado de camundongos expostos a ação do fipronil (ingrediente ativo do acaricida Frontline®)

O fipronil, ingrediente ativo do acaricida Frontiline®, é um derivado fenil-pirazólico e sua eficácia na eliminação de diversas pragas, mesmo em baixas concentrações, já foi demonstrada, porém, sua atuação sobre os organismos não alvos, ainda não foi totalmente esclarecida. Neste sentido, o presente estudo teve por objetivo avaliar os efeitos de diferentes doses do fipronil sobre o fígado de camundongos. Os resultados mostraram que os animais expostos ao fipronil apresentaram alterações ultraestruturais significativas no tecido e nas células hepáticas com evidente desorganização celular e citoplasmática dos hepatócitos, com aumento do número de organelas, principalmente mitocôndrias e retículo endoplasmático rugoso, organelas que, no caso dos indivíduos expostos, foram provavelmente responsáveis pela síntese de enzimas inativadoras do produto tóxico. Houve acúmulo de lipídeos no citoplasma dos hepatócitos (esteatose) além de extensas áreas vacuolizadas, principalmente em regiões próximas ao núcleo. As alterações observadas no núcleo dos hepatócitos sugeriram a ocorrência de processos de morte celular. As células de Kupffer aumentaram em número o que sugerindo aumento de processos fagocitários nos fígados dos animais expostos

Obtenção do pró-fármaco recíproco de isoniazida e metronidazol potencialmente ativo contra Mycobacterium tuberculosis

A tuberculose é uma doença que já atingiu milhares de pessoas no mundo e ainda hoje representa uma ameaça à saúde humana, principalmente a partir da descoberta do vírus HIV. Os fármacos disponíveis no mercado não têm suprimido as necessidades, pois exigem longos períodos de tratamento. Este trabalho teve como objetivo o planejamento e a síntese de um novo composto potencialmente ativo para Mycobacterium tuberculosis na forma latente. O planejamento levou em consideração o princípio da latenciação para a obtenção de um pró-fármaco recíproco derivado de isoniazida e metronidazol. O metronidazol, devido à sua ação em bactérias anaeróbicas poderia apresentar atividade nos bacilos que possivelmente sobrevivam durante o processo de necrose caseosa. A obtenção do pró-fármaco foi realizada através da transformação funcional do metronidazol e posterior acoplamento com isoniazida. O trabalho descreve alguns procedimentos e dificuldades encontradas para obtenção do pró-fármaco. Os resultados sugerem a formação do produto, porém, análises de identificação são necessárias para a confirmação

O processo de envelhecimento e a transição demográfica na cidade de Rio Claro - SP

The proposed work aims to analyze the due process of demographic transition and pronounced population aging present in the city of Rio Claro-SP and the implications that such situation entails the locality. Given that the city is at an advanced point of this phenomenon is noticed a large contingent of people aged over 65 years living on site, so they depend on actions in order to live with dignity. Therefore, the project has the aim of investigating the evolution of population, mainly focusing on the plot elderly, verifying the importance of state enterprises that were present in the town in the lives of citizens, for example, FEPASA and Cesp

Análise dos efeitos do fipronil (ingrediente ativo do Frontline) nas células das glândulas salivares de fêmeas de Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae)

O presente estudo analisou os efeitos da substância química fipronil, ingrediente ativo do Frontline® (acaricida e inseticida), nas glândulas salivares de fêmeas em jejum e semi-ingurgitadas de carrapatos Rhipicephalus sanguineus. As fêmeas em jejum foram expostas apenas à concentração de 1ppm do composto e as semi-ingurgitadas foram expostas a três concentrações de 1ppm, 5ppm e 10ppm (foi utilizada água destilada como controle). Os resultados histológicos e histoquímicos revelaram ação significativa desse composto, alterando morfofisiologicamente o tecido glandular dos indivíduos em jejum e semiingurgitados. Nas fêmeas em jejum, verificaram-se mudanças morfológicas nos ácinos do tipo I, como aumento do tamanho e do diâmetro do seu lúmen. Estas mudanças, provavelmente, estejam relacionadas à função excretora, apontando para os ácinos I como sendo os responsáveis pela eliminação do sistema deste xenobiótico ao qual o parasita foi exposto. Naquelas semi-ingurgitadas, o composto não interferiu no processo de morte que, nestes indivíduos, é por meio de apoptose. Nas fêmeas semi, no entanto, o fipronil acelerou o processo de degeneração das glândulas salivares, que se intensificou (danos mais acentuados) à medida que aumentaram as concentrações do produto. Os dados aqui apresentados deixaram clara a interferência dessa substância no processo de ingurgitamento das fêmeas de R. sanguineus, o que conseqüentemente poderia refletir no seu processo reprodutivo, diminuindo ou mesmo cessando a postura de ovos e provocando menores perdas de sangue nos hospedeiros, reduzindo assim, a transmissão de patógenos veiculados por estas glândulas.

Saúde mental do idoso: percepções relacionadas com o envelhecimento em interface com o atendimento de saúde na atenção básica

Worldwide, growth is seen in the elderly population, which has prompted the use oftechnologies of care that include all stages of life and for that use, it is necessary toprepare professionals to meet this growing demand population. This work aims to understand how old people feel by their condition and identify how old people perceive this treatment in the Family Health Unit. The research is characterized asqualitative and Minayo second analysis was used Bardin. After, thematicinterviews, it was possible to appreciate the topics: Good, dissatisfaction through the life and likes / dislikes of the service unit. This work can be seen that the elderlywho were well, allied to good living with this family, with spouses, autonomy, respect they encounter in society. And when compared with those who have a complaint, we find that lack of family and age restrictions and diseases are the main complaints

Efeito da adição de CGTase e β-ciclodextrina na qualidade e taxa de envelhecimento de pães

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Controle ativo de vibrações em vigas utilizando controle feedforward e elementos espectrais

Pós-graduação em Engenharia Mecânica - FEB