807 resultados para CSCL, Subject-Matter Knowledge, Pedagogical Content Knowledge, Learning Communities


Relevância:

100.00% 100.00%

Publicador:

Resumo:

The fishing industry the world over is passing through a critical situation.The landings of marine fishes seemed to have reached saturation in major fishing areas of the world.As a general rule fisheries employing fishing gear and techniques used by small scale and artisanal fishermen either from shore or from onboard small fishing craft come under small-scale fisheries.This study on gill nets of Kerala, the fishing method depended upon by maximum fishermen of the state focuses on the importance of this selective and low energy fishing method in the marine fishing sector of the state.The study opens with the conceptual framework by briefly reviewing the crisis in the marine fisheries sector. Maximum fishermen depend upon gill net, which is, an important selective and low energy fishing gear. A review of relevant literature on aspects such as material, selectivity and techno-economic efficiency together with scope and main objectives of the study form the major part of the compass of the introductory chapter.This survey provided the inputs for selection of centres. The chapter presents the basis for selection of sample centres, sample units and methodology for field and experimental study.The subject matter of the fourth chapter is a basic study on gear aterials. The weathering resistance, which is an important criterion to assess the material performance, was studied for polyamide monofilament in comparison to polyamide multifilament and polyethylene twisted monofilament.The study provides supporting evidence of oxidation and characteristic C-O stretching in polyethylene and cyclic lactam .formation and presence of OH in polyamide.The study indicates that small mesh gill netting can be encouraged as a selective fishing method in the inshore waters with restrained use of 30 and 32 mm mesh sizes. The economic efficiency was assessed using standard indices such as rate of return, internal rate of return, pay back period, fishery income, energy efficiency and factor productivity. The effect of size and cost of capital and cost of production on the economics of operation is also discussed in this chapter. It was observed that level of technology did not have direct effect on economic performance.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

The work presented in this thesis is centered mainly around delineating the toxic effect of hydrogen sulphide on penaeid prawns and understand its influence on the ecology of estuary. The present investigation also involved characterization of the effects of hydrogen sulphide on the growth and behavioural responses of Penaeus indicus. The test animals employed during the present study namely indicus and Metapenaeus dobsoni are both ecologically and economically relevant. The thesis embodying the details of the investigation has been organized into three chapters comprising Acute toxicity, influence of hydrogen sulphide on the ecology of estuary and effect of hydrogen sulphide on growth and substratum selectivity of penaeid prawn. Each chapter has been partioned into various sections as Introduction, Material and Methods, Results and Discussion for a lucid presentation of the subject matter.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

The present work is organized into six chapters. Bivariate extension of Burr system is the subject matter of Chapter II. The author proposes to introduce a general structure for the family in two dimensions and present some properties of such a system. Also in Chapter II some new distributions, which are bivariate extension of univariate distributions in Burr (1942) is presented.. In Chapter III, concentrates on characterization problems of different forms of bivariate Burr system. A detailed study of the distributional properties of each member of the Burr system has not been undertaken in literature. With this aim in mind in Chapter IV is discussed with two forms of bivariate Burr III distribution. In Chapter V the author Considers the type XII, type II and type IX distributions. Present work concludes with Chapter VI by pointing out the multivariate extension for Burr system. Also in this chapter the concept of multivariate reversed hazard rates as scalar and vector quantity is introduced.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

The nature and extent of protection secured to personal liberty has been a subject matter of great controversy and debate. The expression "procedure established by law" as a standard of protection for personal liberty has been looked upon as highly unsatisfactory and inadequate. For, unlike the specific attributes of liberty that are separately guaranteed under Art.19, ‘personal liberty‘ as guaranteed by Art.21 does not obligate the .Legislature to comply with the requirements of justice and reasonableness as and when it enchroaches upon that right. Though the concept of ‘personal liberty‘ has received an evolutive and expansive meaning through judicial process, the standard of protection which the judicial process could secure to personal liberty through the interpretation of Art.21 has been far from satisfactory Even after four decades of judicial process in the interpretation of Art.21 the problem of evolving a just and adequate standard of protection for personal liberty in that Article continues to be 21 crucial constitutional issue, craving for a. satisfactory solution. And the present study is a humble attempt to unravel this problem and to Search for a reasonable solution.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

The focus of self-assembly as a strategy for the synthesis has been confined largely to molecules, because of the importance of manipulating the structure of matter at the molecular scale. We have investigated the influence of temperature and pH, in addition to the concentration of the capping agent used for the formation of the nano-bio conjugates. For example, the formation of the narrower size distribution of the nanoparticles was observed with the increase in the concentration of the protein, which supports the fact that γ-globulin acts both as a controller of nucleation as well as stabiliser. As analyzed through various photophysical, biophysical and microscopic techniques such as TEM, AFM, C-AFM, SEM, DLS, OPM, CD and FTIR, we observed that the initial photoactivation of γ-globulin at pH 12 for 3 h resulted in small protein fibres of ca. Further irradiation for 24 h, led to the formation of selfassembled long fibres of the protein of ca. 5-6 nm and observation of surface plasmon resonance band at around 520 nm with the concomitant quenching of luminescence intensity at 680 nm. The observation of light triggered self-assembly of the protein and its effect on controlling the fate of the anchored nanoparticles can be compared with the naturally occurring process such as photomorphogenesis.Furthermore,our approach offers a way to understand the role played by the self-assembly of the protein in ordering and knock out of the metal nanoparticles and also in the design of nano-biohybrid materials for medicinal and optoelectronic applications. Investigation of the potential applications of NIR absorbing and water soluble squaraine dyes 1-3 for protein labeling and anti-amyloid agents forms the subject matter of the third chapter of the thesis. The study of their interactions with various proteins revealed that 1-3 showed unique interactions towards serum albumins as well as lysozyme. 69%, 71% and 49% in the absorption spectra as well as significant quenching in the fluorescence intensity of the dyes 1-3, respectively. Half-reciprocal analysis of the absorption data and isothermal titration calorimetric (ITC) analysis of the titration experiments gave a 1:1 stoichiometry for the complexes formed between the lysozyme and squaraine dyes with association constants (Kass) in the range 104-105 M-1. We have determined the changes in the free energy (ΔG) for the complex formation and the values are found to be -30.78, -32.31 and -28.58 kJmol-1, respectively for the dyes 1, 2 and 3. Furthermore, we have observed a strong induced CD (ICD) signal corresponding to the squaraine chromophore in the case of the halogenated squaraine dyes 2 and 3 at 636 and 637 nm confirming the complex formation in these cases. To understand the nature of interaction of the squaraine dyes 1-3 with lysozyme, we have investigated the interaction of dyes 1-3 with different amino acids. These results indicated that the dyes 1-3 showed significant interactions with cysteine and glutamic acid which are present in the side chains of lysozyme. In addition the temperature dependent studies have revealed that the interaction of the dye and the lysozyme are irreversible. Furthermore, we have investigated the interactions of these NIR dyes 1-3 with β- amyloid fibres derived from lysozyme to evaluate their potential as inhibitors of this biologically important protein aggregation. These β-amyloid fibrils were insoluble protein aggregates that have been associated with a range of neurodegenerative diseases, including Huntington, Alzheimer’s, Parkinson’s, and Creutzfeldt-Jakob diseases. We have synthesized amyloid fibres from lysozyme through its incubation in acidic solution below pH 4 and by allowing to form amyloid fibres at elevated temperature. To quantify the binding affinities of the squaraine dyes 1-3 with β-amyloids, we have carried out the isothermal titration calorimetric (ITC) measurements. The association constants were determined and are found to be 1.2 × 105, 3.6× 105 and 3.2 × 105 M-1 for the dyes, 1-3, respectively. To gain more insights into the amyloid inhibiting nature of the squaraine dyes under investigations, we have carried out thioflavin assay, CD, isothermal titration calorimetry and microscopic analysis. The addition of the dyes 1-3 (5μM) led to the complete quenching in the apparent thioflavin fluorescence, thereby indicating the destabilization of β-amyloid fibres in the presence of the squaraine dyes. Further, the inhibition of the amyloid fibres by the squaraine dyes 1-3, has been evidenced though the DLS, TEM AFM and SAED, wherein we observed the complete destabilization of the amyloid fibre and transformation of the fibre into spherical particles of ca. These results demonstrate the fact that the squaraine dyes 1-3 can act as protein labeling agents as well as the inhibitors of the protein amyloidogenesis. The last chapter of the thesis describes the synthesis and investigation of selfassembly as well as bio-imaging aspects of a few novel tetraphenylethene conjugates 4-6.Expectedly, these conjugates showed significant solvatochromism and exhibited a hypsochromic shift (negative solvatochromism) as the solvent polarity increased, and these observations were justified though theoretical studies employing the B3LYP/6-31g method. We have investigated the self-assembly properties of these D-A conjugates though variation in the percentage of water in acetonitrile solution due to the formation of nanoaggregates. Further the contour map of the observed fluorescence intensity as a function of the fluorescence excitation and emission wavelength confirmed the formation of J-type aggregates in these cases. To have a better understanding of the type of self-assemblies formed from the TPE conjugates 4-6, we have carried out the morphological analysis through various microscopic techniques such as DLS, SEM and TEM. 70%, we observed rod shape architectures having ~ 780 nm in diameter and ~ 12 μM in length as evidenced through TEM and SEM analysis. We have made similar observations with the dodecyl conjugate 5 at ca. 70% and 50% water/acetonitrile mixtures, the aggregates formed from 4 and 5 were found to be highly crystalline and such structures were transformed to amorphous nature as the water fraction was increased to 99%. To evaluate the potential of the conjugate as bio-imaging agents, we have carried out their in vitro cytotoxicity and cellular uptake studies though MTT assay, flow cytometric and confocal laser scanning microscopic techniques. Thus nanoparticle of these conjugates which exhibited efficient emission, large stoke shift, good stability, biocompatibility and excellent cellular imaging properties can have potential applications for tracking cells as well as in cell-based therapies. In summary we have synthesized novel functional organic chromophores and have studied systematic investigation of self-assembly of these synthetic and biological building blocks under a variety of conditions. The investigation of interaction of water soluble NIR squaraine dyes with lysozyme indicates that these dyes can act as the protein labeling agents and the efficiency of inhibition of β-amyloid indicate, thereby their potential as anti-amyloid agents.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Lean is common sense and good business sense. As organizations grow and become more successful, they begin to lose insight into the basic truths of what made them successful. Organizations have to deal with more and more issues that may not have anything to do with directly providing products or services to their customers. Lean is a holistic management approach that brings the focus of the organization back to providing value to the customer. In August 2002, Mrs. Darleen Druyun, the Principal Deputy to the Assistant Secretary of the Air Force for Acquisition and government co-chairperson of the Lean Aerospace Initiative (LAI), decided it was time for Air Force acquisitions to embrace the concepts of lean. At her request, the LAI Executive Board developed a concept and methodology to employ lean into the Air Force’s acquisition culture and processes. This was the birth of the “Lean Now” initiative. An enterprise-wide approach was used, involving Air Force System Program Offices (SPOs), aerospace industry, and several Department of Defense agencies. The aim of Lean Now was to focus on the process interfaces between these “enterprise” stakeholders to eliminate barriers that impede progress. Any best practices developed would be institutionalized throughout the Air Force and the Department of Defense (DoD). The industry members of LAI agreed to help accelerate the government-industry transformation by donating lean Subject Matter Experts (SMEs) to mentor, train, and facilitate the lean events of each enterprise. Currently, the industry SMEs and the Massachusetts Institute of Technology are working together to help the Air Force develop its own lean infrastructure of training courses and Air Force lean SMEs. The first Lean Now programs were the F/A-22, Global Hawk, and F-16. Each program focused on specific acquisition processes. The F/A-22 focused on the Test and Evaluation process; the Global Hawk focused on Evolutionary Acquisitions; and the F-16 focused on improving the Contract Closeout process. Through lean, each enterprise made many significant improvements. The F/A-22 was able to reduce its Operational Flight Plan (OFP) Preparation and Load process time of 2 to 3 months down to 7 hours. The Global Hawk developed a new production plan that increases the annual production of its Integrated Sensor Suite from 3 per year to 6 per year. The F-16 enterprise generated and is working 12 initiatives that could result in a contract closeout cycle time reduction of 3 to 7 years. Each enterprise continues to generate more lean initiatives that focus on other areas and processes within their respective enterprises.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

This paper summarizes a number of observations and reflections on the phenomenon and practice called “reconciliation”, in connection to peace processes and peace-building initiatives. In particular it draws from processes followed by the author, in East Timor in particular, but also in Europe, the Middle East and, more recently, Colombia. It is a discussion paper. The purpose is to invite to reflection, both on the level of perspectives as well as concepts. It is developed from a lecture called “The Challenge of Reconciliation” held at Universidad Nacional, Bogotá, in December 2003. Following substantial revision since then (making the text more than double in length) I realize that today not many parts of the original text are still recognizable from that presentation, then organized by the Embassy of Sweden in Colombia, as part of its commitment to the peace process in that country. I have accepted the invitation of the Center of Political and International Studies (Centro de Estudios Políticos e Internacionales, CEPI), at Universidad del Rosario, to publish this work in progress, to reach a broader public in Colombia and contribute to the discussion on econciliation. The field of “political reconciliation” is evolving, definitions of reconciliation are abounding, and different contributors have different takes on the subject matter, quite naturally. It is the author’s view, that reconciliation can and should not be “held captive” of any particular field of study. It relates to fundamental, some would call it existential, issues of meaning, trust, contradictions, and suffering in the midst of a violent, political reality. It is wise to tread softly on ground with such a complex bottom.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

En noviembre del 2009 después de varias mesas de trabajo entre el sector público, el sector privado, la comunidad y expertos del tema de las veinte localidades del Distrito Capital nace como resultado de un proceso de participación y concertación con los diferentes actores de la comunidad, la política pública de deporte, recreación y actividad física para Bogotá “Bogotá más activa” 2009 2019. El proceso de participación se realizó por medio de 40 talleres, dos por localidad, durante los meses de octubre y noviembre del 2008, donde se garantizaron los espacios para debatir los temas más importantes según la consideración de las diferentes comunidades. La participación ciudadana es el objeto de estudio de la investigación, en este contexto, la pregunta de investigación que se pretende responder a lo largo de este trabajo es: ¿Cuál fue el papel de la participación ciudadana en la formulación de la política pública de deporte, recreación y actividad física para Bogotá “Bogotá más activa” 2009-2019 en la localidad de Suba?.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

El terrorismo en la actualidad es considerado como uno de los conceptos más controversiales en los campos social, académico y político. El término se empieza a utilizar después de la Revolución Francesa, pero recientemente, a raíz de los atentados del 11 de septiembre de 2001, ha tomado suma relevancia y ha motivado numerosas investigaciones para tratar de entender qué es terrorismo. Aunque a la fecha existen varias revisiones sistemáticas, este trabajo tiene como propósito revisar, agrupar y concretar diferentes teorías y conceptos formulados por los autores que han trabajado sobre el concepto de “terrorismo” con el fin de entender las implicaciones de su utilización en el discurso, y cómo esto afecta la dinámica interna de las sociedades en relación con la violencia, las creencias, los estereotipos entre otros elementos. Para lograrlo, se revisaron 56 artículos, publicados entre los años 1985 y 2013; 10 fuentes secundarias entre noticias y artículos de periódicos correspondientes a los años 1995-2013 y 10 estudios estadísticos cuyos resultados nos aportan a la comprensión del tema en cuestión. La búsqueda se limitó al desarrollo histórico del terrorismo, sus diferentes dimensiones y el concepto social de la realidad de terrorismo. Los hallazgos demuestran que la palabra “terrorismo” constituye un concepto que como tal es un vehículo lingüístico que puede ser utilizado con fines, estratégicos movilizando al público conforme a través del discurso e intereses políticos, destacando la necesidad de estudiar las implicaciones psicológicas y sociales de su uso.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Manuel Ancízar published in 1851 his Lectures on Psychology. The text has been a representative of the interests of Colombian intellectuals of the time for discipline. The treatise of the history of psychology Colombia have considered the nineteenth century as a period characterized by a poorly conceived attempt to import some emerging professional practices of psychiatric and educational type. However, the work of Ancízar showed large exhibition on the subject matter of psychology: human consciousness and the theories that support the formation of the new science. The core of the work is oriented towards the secular drama, against which Ancízar defended the supernatural origin and nature of the human soul. The author introduced an eclectic psychology in which, the secular orientation of modern ideas are integrated with the conception of the soul as a divine gift. The reading of the work has been outstanding and indispensable work for understanding ancient and autochthonous forms of access to psychological issues.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

El autor se interroga acerca de si el Consejo Nacional de Planeación, al igual que los consejos territoriales, son escenarios para el ejercicio de la democracia y si su participación, en la construcción de los planes de desarrollo, constituye un instrumento eficaz para su fortalecimiento o son, por el contrario, un espejismo en la praxis de la democracia en Colombia. En la primera parte se mencionan algunas versiones de democracia desde Lincoln, pasando por las versiones de Tocqueville, Shumpeter, Dahl, Bryce, Borón y Sartori. Se identifican en cada caso los elementos fundamentales para tenerlos como referente y soporte de análisis para dar cuenta, en la segunda parte, cuál o cuáles formas de esas democracias describen el modus operandi en el seno de los consejos de planeación en los niveles nacional o territorial. Igualmente se analiza el rol de los consejos de planeación, su legitimidad, la calidad y trascendencia de las intervenciones de sus miembros, así como la capacidad de incidir en el proyecto de ley del Plan Nacional de Desarrollo, para lo cual se recurre a entrevistar a miembros y ex miembros de los consejos Nacional y Distrital de planeación. El autor, además de responder algunos interrogantes que se plantea sobre el tema objeto de esta reflexión, deja planteados otros para la consideración de los lectores.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

The subject matter of the analysis conducted in the text is information and anti-terrorist security of Poland, which has been presented within the context of a clash between two spheres – the state and the private sphere. Furthermore, the issues of security have been supplemented with a description of the tasks and activity of the Internal Security Agency, as well as a synthetic appraisal of a terrorist threat to Poland. The main parts of this work are concerned with: (1) the state and the private sphere, (2) " terrorism " and terrorist offences, (3) the tasks and activity of the Internal Security Agency, (4) an appraisal of a terrorist threat to Poland. Given the necessity to elaborate the research problem, the text features the following research questions: (1) To what extent does referring to a threat to security influence a limitation on rights and freedoms in Poland (with regard to the clash between the state and the private sphere)?, (2) To what extent do the tasks and activity of the Internal Security Agency influence the effectiveness of anti-terrorist security in Poland?

Relevância:

100.00% 100.00%

Publicador:

Resumo:

El autor lee a Carrera Andrade como un creador surgido en el quiebre de los presupuestos, ideologías y esperanzas del siglo XIX e inicios del XX, más plagado de incertidumbres que de certezas. Acaso el rasgo autobiográfico de su poesía, y su apego a una temática múltiple –no apartada nunca del desciframiento de los sentidos de lo pequeño– han oscurecido la intención del autor de reflexionar sobre la condición y el destino del hombre moderno. Cercano al existencialismo, en tanto filosofía develadora de la fragilidad y soledad humanas, de la futilidad de sus construcciones intelectuales, Carrera fue testigo –en un siglo de confrontaciones– «de la fealdad triunfante y la libertad encadenada». El poeta describe tres atributos definitorios del hombre moderno: soledad, imposibilidad de ser libre, y su condición de desterrado. Plantea Carrera que estas condiciones ontológicas de soledad y de ser prisionero no se agotarían en el hombre, sino que conformarían también a otros seres y objetos del universo. El destierro aludiría no solo a la condición literal del exiliado, sino también a la ausencia de un hogar espiritual, aunque, en relación a este punto, parece arribar a una cierta conciliación mediante la idea de que es posible trascender la finitud del individuo en la pervivencia de la humanidad entera –destino común el del «hombre planetario», cantado por el poeta a pesar de su soledad y sus prisiones.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Este artículo analiza la concepción del derecho a la tutela judicial efectiva como derecho fundamental, para lo cual parte de sus notas configuradoras básicas. Al efecto, se estudian sus implicaciones desde el ámbito constitucional y del Código Orgánico de la Función Judicial, como sus líneas directrices en la doctrina y en la jurisprudencia del Tribunal Constitucional español (órgano que ha estudiado ampliamente el tema), para luego determinar cómo se ha considerado el ámbito del derecho por los tribunales ecuatorianos.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

El desarrollo de la presente tesis es hacer un estudio comparativo de la implementación de los tributos Medioambientales en nuestro país, a partir de la experiencia de la Comunidad Europea quienes desarrollaron y siguen desarrollando la protección y conservación del Medio Ambiente a través de la imposición tributaria. En ese sentido partimos definiendo y precisando el término Medio Ambiente y ecología a fin de delimitar el tema de estudio, ya que el objetivo de la tesis es identificar las formas o mecanismos de protección del Medio Ambiente, enfatizando en la imposición Medioambiental que pueden ser a través de los impuestos, tasas o contribuciones; además de la consideración por nuestra Constitución del medio ambiente como un derecho humano fundamental de los seres humanos. Durante el desarrollo de la tesis, exponemos los instrumentos nacionales e internacionales, cuya finalidad busca garantizar la protección y conservación del Medio Ambiente, bajo el principio “quien contamina paga”, que no es otra cosa que la el criterio objetivo en la que el sujeto que deteriora o contamina el Medio Ambiente debe ser el responsable de reparar el daño causado. Finalmente analizamos la viabilidad de la protección del Medio Ambiente en los países andinos y en nuestro texto constitucional.