946 resultados para 2-THIOBENZYL-4,6-DIMETHYL-PYRIMIDINE


Relevância:

100.00% 100.00%

Publicador:

Resumo:

Survey map of the Second Welland Canal created by the Welland Canal Company showing south Merritton along the boundary between the Grantham and Thorold Townships. Identified structures associated with the Canal include Locks 19, 20, 21, and 22, Lock Tenders House, and the towing path. The surveyors' measurements and notes can be seen in red and black ink and pencil. Local area landmarks are also identified and include streets and roads (ex. Pine Street and Macadamized Road), J. Brown Cement Mill, W. B. Hendershot Saw Mill, W. Parnall Spoke and Sash Factory, W. Beatty Saw Mill, W. Beatty Tannery, a number of structures (possibly houses) belonging to: Mrs. Aikins, J. Battle, and E. Keefer, and a foundry, smithy, and machine shop (all of which possible belonged to J. Dobbie). Properties and property owners of note are: Concession 10 Lots 9 and 10, W. C. Loan Company, P.H. Ball, and J. Keefer. Two small properties belonging to W. B. Hendershot and W. Beatty exist and are outlined in red. A half acre property reserved for a lock lot exists and is outlined in blue. An additional property reserved for a quarry is also identified, but not outlined.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

A blueprint produced by Westinghouse Electric & MFG. Co. in Pittsburgh, Pennsylvanna. The blueprint is dated 19 August 1903 and is stamped "OBSOLETE".

Relevância:

100.00% 100.00%

Publicador:

Resumo:

The Constitution, Toronto, Upper Canada (2 copies), September 6, 1837.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Tesis (Maestría en Ciencias con Especialidad en Química Orgánica) UANL

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Tesis (Maestría en Ciencias Químicas, con especialidad en Química Orgánica) U.A.N.L.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Pour toute demande de reproduction de contenu se trouvant dans cette publication, communiquer avec l’Association des diplômés de l’UdeM.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Ponent: Maria Puig de la Bellacasa / Presenta: Víctor Jorquera

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Ponent: Anna Ortiz / Presenta: Bárbara Biglia

Relevância:

100.00% 100.00%

Publicador:

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Colección de cinco tebeos que sirve de material de apoyo para el tratamiento de la prevención de accidentes infantiles en la escuela. Este documento está integrado en los documentos de apoyo al desarrollo de la Educación para la Salud. El objetivo es que los alumnos tengan útiles necesarios para adquirir estilos de vida sanos y responsables acerca de su salud y la de los demás. El carácter lúdico que se plantea con estos tebeos, facilita el desarrollo de los temas de prevención desde una perspectiva personal, teniendo en cuenta los niveles de maduración del alumno. Los títulos que componen esta serie giran en torno a una familia (Martín Castaño), con los contenidos siguientes: las caídas, las quemaduras, la carga del trabajo, los productos tóxicos y los riesgos eléctricos.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

The release of growth factors from tissue engineering scaffolds provides signals that influence the migration, differentiation, and proliferation of cells. The incorporation of a drug delivery platform that is capable of tunable release will give tissue engineers greater versatility in the direction of tissue regeneration. We have prepared a novel composite of two biomaterials with proven track records - apatite and poly(lactic-co-glycolic acid) (PLGA) – as a drug delivery platform with promising controlled release properties. These composites have been tested in the delivery of a model protein, bovine serum albumin (BSA), as well as therapeutic proteins, recombinant human bone morphogenetic protein-2 (rhBMP-2) and rhBMP-6. The controlled release strategy is based on the use of a polymer with acidic degradation products to control the dissolution of the basic apatitic component, resulting in protein release. Therefore, any parameter that affects either polymer degradation or apatite dissolution can be used to control protein release. We have modified the protein release profile systematically by varying the polymer molecular weight, polymer hydrophobicity, apatite loading, apatite particle size, and other material and processing parameters. Biologically active rhBMP-2 was released from these composite microparticles over 100 days, in contrast to conventional collagen sponge carriers, which were depleted in approximately 2 weeks. The released rhBMP-2 was able to induce elevated alkaline phosphatase and osteocalcin expression in pluripotent murine embryonic fibroblasts. To augment tissue engineering scaffolds with tunable and sustained protein release capabilities, these composite microparticles can be dispersed in the scaffolds in different combinations to obtain a superposition of the release profiles. We have loaded rhBMP-2 into composite microparticles with a fast release profile, and rhBMP-6 into slow-releasing composite microparticles. An equi-mixture of these two sets of composite particles was then injected into a collagen sponge, allowing for dual release of the proteins from the collagenous scaffold. The ability of these BMP-loaded scaffolds to induce osteoblastic differentiation in vitro and ectopic bone formation in a rat model is being investigated. We anticipate that these apatite-polymer composite microparticles can be extended to the delivery of other signalling molecules, and can be incorporated into other types of tissue engineering scaffolds.

Relevância:

100.00% 100.00%

Publicador:

Resumo:

Nova et Vetera, ISSN 1692 - 5866, Año 8 No. 2 (Febrero 04 - 10 de 2013)

Relevância:

100.00% 100.00%

Publicador:

Resumo:

La matemática pasa por reencontrar su sentido originario de la lengua de comunicación y de dominio del entorno, para lo que fue creada. Una matemática viva y significativa donde la comprensión del entorno y la realidad son los parámetros fundamentales.