Análise de equilíbrio corporal submetido á esforços de aceleração e desaceleração na direção antero-posterior: estudo transversal

Pós-graduação em Engenharia Mecânica - FEG

Effects of active and passive lacebacks on antero-posterior position of maxillary first molars and central incisors

The purpose of this study was to compare the effects of active and passive lacebacks on antero-posterior position of maxillary first molars and central incisors during leveling phase. Twenty-three subjects with Class I and Class II malocclusion were treated with first premolars extraction using preadjusted appliances (MBT 0.022-inch brackets). The leveling phase was performed with stainless steel archwires only. The sample was divided into 2 groups: 14 subjects received active lacebacks (Group 1) and 9 subjects received passive lacebacks (Group 2). Lacebacks were made from 0.008-inch ligature wire. Lateral cephalometric radiographs were taken pre- and post-leveling phase. Student's t-test was applied to determine the differences between pre- and post-leveling mean values and to determine the mean differences between groups. In Group I, the first molars showed a significant mesial movement, whereas no change was observed in Group 2. In both groups, maxillary central incisor crowns moved to lingual side. In conclusion, active laceback produced anchorage loss of maxillary first molars whereas passive laceback did not affect the position of these teeth. Active and passive lacebacks were effective in preventing central incisor proclination.

Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis

BACKGROUND: Endoderm organ primordia become specified between gastrulation and gut tube folding in Amniotes. Although the requirement for RA signaling for the development of a few individual endoderm organs has been established a systematic assessment of its activity along the entire antero-posterior axis has not been performed in this germ layer. METHODOLOGY/PRINCIPAL FINDINGS: RA is synthesized from gastrulation to somitogenesis in the mesoderm that is close to the developing gut tube. In the branchial arch region specific levels of RA signaling control organ boundaries. The most anterior endoderm forming the thyroid gland is specified in the absence of RA signaling. Increasing RA in anterior branchial arches results in thyroid primordium repression and the induction of more posterior markers such as branchial arch Hox genes. Conversely reducing RA signaling shifts Hox genes posteriorly in endoderm. These results imply that RA acts as a caudalizing factor in a graded manner in pharyngeal endoderm. Posterior foregut and midgut organ primordia also require RA, but exposing endoderm to additional RA is not sufficient to expand these primordia anteriorly. We show that in chick, in contrast to non-Amniotes, RA signaling is not only necessary during gastrulation, but also throughout gut tube folding during somitogenesis. Our results show that the induction of CdxA, a midgut marker, and pancreas induction require direct RA signaling in endoderm. Moreover, communication between CdxA(+) cells is necessary to maintain CdxA expression, therefore synchronizing the cells of the midgut primordium. We further show that the RA pathway acts synergistically with FGF4 in endoderm patterning rather than mediating FGF4 activity. CONCLUSIONS/SIGNIFICANCE: Our work establishes that retinoic acid (RA) signaling coordinates the position of different endoderm organs along the antero-posterior axis in chick embryos and could serve as a basis for the differentiation of specific endodermal organs from ES cells.

Statistical model-based segmentation of the proximal femur in digital antero-posterior (AP) pelvic radiographs.

PURPOSE    Segmentation of the proximal femur in digital antero-posterior (AP) pelvic radiographs is required to create a three-dimensional model of the hip joint for use in planning and treatment. However, manually extracting the femoral contour is tedious and prone to subjective bias, while automatic segmentation must accommodate poor image quality, anatomical structure overlap, and femur deformity. A new method was developed for femur segmentation in AP pelvic radiographs. METHODS    Using manual annotations on 100 AP pelvic radiographs, a statistical shape model (SSM) and a statistical appearance model (SAM) of the femur contour were constructed. The SSM and SAM were used to segment new AP pelvic radiographs with a three-stage approach. At initialization, the mean SSM model is coarsely registered to the femur in the AP radiograph through a scaled rigid registration. Mahalanobis distance defined on the SAM is employed as the search criteria for each annotated suggested landmark location. Dynamic programming was used to eliminate ambiguities. After all landmarks are assigned, a regularized non-rigid registration method deforms the current mean shape of SSM to produce a new segmentation of proximal femur. The second and third stages are iteratively executed to convergence. RESULTS    A set of 100 clinical AP pelvic radiographs (not used for training) were evaluated. The mean segmentation error was [Formula: see text], requiring [Formula: see text] s per case when implemented with Matlab. The influence of the initialization on segmentation results was tested by six clinicians, demonstrating no significance difference. CONCLUSIONS    A fast, robust and accurate method for femur segmentation in digital AP pelvic radiographs was developed by combining SSM and SAM with dynamic programming. This method can be extended to segmentation of other bony structures such as the pelvis.

The Exploration and Development of Alternative Management Strategies for Mining and Recreational Activities Atop Mount Antero and Mount White; Chaffee County, Colorado

The Mount Antero/White area is a popular prospecting area. Recent expansions in the recreation economy is drawing more visitors to the area. Consequently, visitors may be placing unsustainable pressures on the landscape. In order to help rectify this, the legal, ecological, geologic, aesthetic, recreational, historic, social, and economic character of the Antero/White area has been identified. Four feasible management alternatives have also been recognized. They are a) take no new management actions, b) prohibit motorized activities in the area, c) develop a mineralogical park, and d) a combination of options b and c. Option C has been defended, as it best balances the desires of area users with the underlying ecological and geological character of the area.

Punahilkalla on ollut eväät kunnossa – Antero Mertarannan jääkiekkoselostusten intertekstuaaliset kielen piirteet

Tutkin urheilutoimittaja Antero Mertarannan jääkiekkoselostusten kielen piirteitä. Litteroimani aineisto on MM-kisoista keväältä 2011, ja analysoin niitä kielen piirteitä, joita voi toistuvuuden perusteella pitää Mertarannalle ominaisina. Tutkimustani läpäisevä käsite on intertekstuaalisuus: Mistä se selostukseen kirvoittuu? Miten se vaikuttaa selostukseen? Pureudun tarkasti myös mielikuviin, joita Mertaranta luo sekä joukkueista että pelaajista. Hyödynnän analyysissani Norman Faircloughin (1992) perustavan intertekstuaalisuuden ja avoimen intertekstuaalisuuden käsitteitä. Mertarannalla intertekstuaalisuuden ensimmäinen virike tulee pelitilanteesta, joka käynnistää assosiaatioketjun. Assosiaatiot kumpuavat herkästi pelaajan ominaispiirteistä ja joukkueen edustamasta maasta. Suomalaisten kuvailussa on useimmiten alluusio suomalaiseen musiikkiin. Mertarannan selostuksessa on kertomuksen, kansallisromanttisen kuvailun ja show-juonnon elementtejä, ja lisäksi hän muuntelee sananlaskuja ja idiomeja pelitilanteisiin sopiviksi. Mertaranta myös imitoi pelaajia: Vastustajien referointi alkaa lähes aina kysymyksellä, jolloin vastustaja näyttäytyy hölmistyneessä valossa. Suomalaisten referoinnit taas hohkaavat itsevarmuutta. Intertekstuaalisuus osoittautuu Mertarannan huumorin perustaksi.

Literatura portuguesa moderna e contemporânea : a personalidade literária de Antero de Quental

Académico - Licenciaturas

Qualificação à saúde dos escolares de 06 a 17 anos da Escola Municipal Jornalista Antero Cardoso Filho em Parnaíba-PI

O Programa Saúde na Escola – PSE tem como escopo o fortalecimento das ações destinadas às crianças, adolescentes, jovens e adultos da comunidade escolar com o intuito de lhes garantir um desenvolvimento pleno. Através da articulação entre saúde e educação, o programa busca contribuir para a formação integral dos educandos, dando ênfase às ações de promoção e atenção à saúde e de prevenção de agravos. O PSE está inserido na Política Nacional de Atenção Básica – PNAB, constituindo uma das ferramentas para o funcionamento da atenção básica. Este trabalho teve como objetivo melhorar a atenção à saúde dos escolares de 6 a 17 anos da Escola Municipal Jornalista Antero Cardoso Filho da área adstrita da Unidade Básica de Saúde Francisco Diassis de Souza – Planalto, Parnaíba PI, por meio da realização dos três componentes do PSE: avaliação clínica e psicossocial, promoção e prevenção à saúde e formação. É o relato de uma intervenção de 12 semanas com ações desenvolvidas em quatro eixos de trabalho: organização e gestão do serviço, monitoramento e avaliação das ações, qualificação da prática clínica e engajamento público. A intervenção propiciou a realização de todos os componentes do Programa Saúde na Escola, através dos quais se ampliou a cobertura da atenção à saúde dos 260 alunos matriculados, a implantação dos registros e a qualificação da atenção, tendo como principal resultado a cobertura de 100% dos alunos. Com as ações de prevenção e promoção da saúde realizadas, o agendamento das consultas para aqueles que necessitam ser encaminhados para o médico e o referenciamento para os especialistas, garantiu-se uma assistência de qualidade para aqueles que estão estudando. Aos profissionais da unidade básica de saúde e da escola contribuiu-se positivamente através das ações de educação permanente e das capacitações realizadas. Para a comunidade, o principal benefício da intervenção foi a garantia de assistência aos alunos da referida escola. A UBS pretende dar continuidade às atividades desenvolvidas nesses três meses, incorporando as ações do PSE às rotinas do serviço. Percebe-se, portanto, que a intervenção foi de suma importância para a implantação do PSE, trazendo melhorias na qualidade de vida dos educandos e contribuindo para uma maior integração entre UBS/escola/comunidade.

Spinal Cord Damage In Machado-joseph Disease.

Machado-Joseph disease (SCA3) is the most frequent spinocerebellar ataxia worldwide and characterized by remarkable phenotypic heterogeneity. MRI-based studies in SCA3 focused in the cerebellum and connections, but little is known about cord damage in the disease and its clinical relevance. To evaluate the spinal cord damage in SCA3 through quantitative analysis of MRI scans. A group of 48 patients with SCA3 and 48 age and gender-matched healthy controls underwent MRI on a 3T scanner. We used T1-weighted 3D images to estimate the cervical spinal cord area (CA) and eccentricity (CE) at three C2/C3 levels based on a semi-automatic image segmentation protocol. The scale for assessment and rating of ataxia (SARA) was employed to quantify disease severity. The two groups-SCA3 and controls-were significantly different regarding CA (49.5 ± 7.3 vs 67.2 ± 6.3 mm(2), p < 0.001) and CE values (0.79 ± 0.06 vs 0.75 ± 0.05, p = 0.005). In addition, CA presented a significant correlation with SARA scores in the patient group (p = 0.010). CE was not associated with SARA scores (p = 0.857). In the multiple variable regression, we found that disease duration was the only variable associated with CA (coefficient = -0.629, p = 0.025). SCA3 is characterized by cervical cord atrophy and antero-posterior flattening. In addition, the spinal cord areas did correlate with disease severity. This suggests that quantitative analyses of the spinal cord MRI might be a useful biomarker in SCA3.

Aspectos motores da Paralisia Cerebral Espástica diparética : o Nintendo WII 'MARCA REGISTRADA' como atividade motora complementar = Motor aspects of Spastic Cerebral Palsy : the Nintendo WII 'TRADEMARK' as a supplementary motor activity

Universidade Estadual de Campinas . Faculdade de Educação Física

Cognitive control associated with irritability induction: an autobiographical recall fMRI study

OBJECTIVE: Despite the relevance of irritability emotions to the treatment, prognosis and classification of psychiatric disorders, the neurobiological basis of this emotional state has been rarely investigated to date. We assessed the brain circuitry underlying personal script-driven irritability in healthy subjects (n = 11) using functional magnetic resonance imaging. METHOD: Blood oxygen level-dependent signal changes were recorded during auditory presentation of personal scripts of irritability in contrast to scripts of happiness or neutral emotional content. Self-rated emotional measurements and skin conductance recordings were also obtained. Images were acquired using a 1,5T magnetic resonance scanner. Brain activation maps were constructed from individual images, and between-condition differences in the mean power of experimental response were identified by using cluster-wise nonparametric tests. RESULTS: Compared to neutral scripts, increased blood oxygen level-dependent signal during irritability scripts was detected in the left subgenual anterior cingulate cortex, and in the left medial, anterolateral and posterolateral dorsal prefrontal cortex (cluster-wise p-value < 0.05). While the involvement of the subgenual cingulate and dorsal anterolateral prefrontal cortices was unique to the irritability state, increased blood oxygen level-dependent signal in dorsomedial and dorsal posterolateral prefrontal regions were also present during happiness induction. CONCLUSION: Irritability induction is associated with functional changes in a limited set of brain regions previously implicated in the mediation of emotional states. Changes in prefrontal and cingulate areas may be related to effortful cognitive control aspects that gain salience during the emergence of irritability.