Clostridium difficile infection (CDI) in HIV-positive patients

The main aim of this study was to look at the association of Clostridium difficile infection (CDI) and HIV. A secondary goal was to look at the trend of CDI-related deaths in Texas from 1999-2011. To evaluate the coinfection of CDI and HIV, we looked at 2 datasets provided by CHS-TDSHS, for 13 years of study period from 1999-2011: 1) Texas death certificate data and 2) Texas hospital discharge data. An ancillary source of data was national level death data from CDC. We did a secondary data analysis and reported the age-adjusted death rates (mortality) and hospital discharge frequencies (morbidity) for CDI, HIV and for CDI+HIV coinfection.^ Since the turn of the century, CDI has reemerged as an important public health challenge due to the emergence of hypervirulent epidemic strains. From 1999-2011, there has been a significant upward trend in CDI-related death rates; in the state of Texas alone, CDI mortality rate has increased 8.7 fold in this time period at the rate of 0.2 deaths per year per 100,000 individuals. On the contrary, mortality due to HIV has decreased by 46% and has been trending down. The demographic groups in Texas with the highest CDI mortality rates were elderly aged 65+, males, whites and hospital inpatients. The epidemiology of C. difficile has changed in such a way that it is not only staying confined to these traditional high-risk groups, but is also being increasingly reported in low-risk populations such as healthy people in the community (community acquired C. difficile), and most recently immunocompromised patients. Among the latter, HIV can worsen the adverse health outcomes of CDI and vice versa. In patients with CDI and HIV coinfection, higher mortality and morbidity was found in young & middle-aged adults, blacks and males, the same demographic population that is at higher risk for HIV. As with typical CDI, the coinfection was concentrated in the hospital inpatients. Of all the CDI-related deaths in USA from 1999-2010, in the 25-44 year age group, 13% had HIV infection. Of all CDI-related inpatient hospital discharges in Texas from 1999-2011, in patients 44 years and younger, 17% had concomitant HIV infection. Therefore, HIV is a possible novel emerging risk factor for CDI.^

Subsurface time series of chlorophyll a at the PhytoCly station, Bay of Calvi, Corsica, Mediterranean Sea

The development of the winter-spring phytoplankton bloom was investigated in the Bay of Calvi (Corsica, Ligurian Sea, northwestern Mediterranean) in 1979, 1986, 1988, 1997 and 1998. A drastic reduction of phytoplankton biomass was evidenced over the last 2 decades, in relation to long-term changes in climatic and environmental conditions. Between 1979 and 1998, the monthly averaged chlorophyll a concentrations at 1 m decreased by about 80% during February, March and April. Simultaneously, major changes to hydrodynamic conditions include warmer water, overall decrease of salinity at 10 m depth, longer periods of bright sunshine and lower wind stress. The changes in environmental conditions were large enough to affect the vertical stability of the water column during the winter-spring period and to reduce nutrient replenishment of the surface layer prior to the usual period of phytoplankton growth. Until 1986, the main factor driving nutrient replenishment was the winter upward mixing of nutrient-rich deep waters, while the progressive reduction of mixing from 1988 induced nutrient limitation of surface waters in the last decade. The following hypotheses on changes in the development of the winter-spring phytoplankton bloom are made: (1) Until 1986, phytoplankton peaks took place in relatively high-nutrient waters and were diatom-dominated. (2) Between 1986 and 1988, decreasing Si availability led to Si limitation which caused a reduction in diatom abundance. This resulted in the disappearance of the diatom-dominated pulses and in lower phytoplankton biomass and was accompanied by a shift toward non-siliceous phytoplankton. (3) In 1988, 1997 and 1998, decreasing nitrate availability led to nitrate limitation, thus explaining the progressive reduction in non-siliceous phytoplankton biomass. Other, associated changes in benthos assemblages and ichthyofauna are documented. The conclusions from the Bay of Calvi are extended to the whole western Corsican coast. This confirms that the Mediterranean reacts rapidly to external perturbations, which are driven by climate change in that particular area.

The history of technology in education. A comparative study and forecast

Area, launched in 1999 with the Bologna Declaration, has bestowed such a magnitude and unprecedented agility to the transformation process undertaken by European universities. However, the change has been more profound and drastic with regards to the use of new technologies both inside and outside the classroom. This article focuses on the study and analysis of the technology’s history within the university education and its impact on teachers, students and teaching methods. All the elements that have been significant and innovative throughout the history inside the teaching process have been analyzed, from the use of blackboard and chalk during lectures, the use of slide projectors and transparent slides, to the use of electronic whiteboards and Internet nowadays. The study is complemented with two types of surveys that have been performed among teachers and students during the school years 1999 - 2011 in the School of Civil Engineering at the Polytechnic University of Madrid. The pros and cons of each of the techniques and methodologies used in the learning process over the last decades are described, unfolding how they have affected the teacher, who has evolved from writing on a whiteboard to project onto a screen, the student, who has evolved from taking handwritten notes to download information or search the Internet, and the educational process, that has evolved from the lecture to acollaborative learning and project-based learning. It is unknown how the process of learning will evolve in the future, but we do know the consequences that some of the multimedia technologies are having on teachers, students and the learning process. It is our goal as teachers to keep ourselves up to date, in order to offer the student adequate technical content, while providing proper motivation through the use of new technologies. The study provides a forecast in the evolution of multimedia within the classroom and the renewal of the education process, which in our view, will set the basis for future learning process within the context of this new interactive era.

Tracking 10-year competitive winning performance of judo athletes across age groups

Little information is available concerning early specialization and competitive success in judo across the early training years. Thus, the present objective was to verify the stability of individual competitive performance of a state-level championship for judo athletes who had been previously successful. For this, 406 athletes from six age groups (9 to 20+ years old) of each sex were followed for 10 years. Using recorded data from the Sao Paulo State Judo Federation beginning in 1999, the scores and standings for these judo players were analyzed. The proportion of medal winners during this period was not constant, differing from the grand mean in all groups of both 204 males and 202 females. At the end of this period, only 7% of the male and 5% of the female athletes had maintained their competitive levels. Successful competitive performance in early judo competition was not associated with success later in adulthood.

Indicador de perdurabilidad empresarial aplicado a las empresas con mejor posicionamiento en Colombia desde 1999 a 2011

La perdurabilidad y las estrategias competitivas marcan la tendencia del siglo XXI, aportando consejos y sugerencias para que los empresarios tomen decisiones en pro del éxito empresarial a lo largo del tiempo. Los estudios de perdurabilidad empresarial son realmente importantes para la administración y para los empresarios puesto que gracias a ellos se puede observar cómo las empresas exitosas llevan su dirección para sobrevivir en el tiempo cumpliendo satisfactoriamente los objetivos de la empresa. El presente proyecto de grado busca comprender los diferentes estudios para medir la perdurabilidad empresarial y escoger la mejor opción que permita interpretar los resultados obtenidos, resaltar aquellos que son importantes y hacer que la información analizada se vuelva útil para tomar decisiones estratégicas que contribuyan a la ejecución de empresas perdurables.

Análisis de la política exterior de Irán y su influencia sobre la política de Seguridad y defensa de Israel. Período 2005-2011

En la presente monografía se analizarán los factores de la política exterior iraní que han incidido en la política de seguridad y defensa de Israel. Se examina y explica bajo la teoría del Realismo Ofensivo, cuyo máximo representante es John Mearsheimer, el cual expone acerca las dinámicas de los países desarrollados con respecto al ámbito de seguridad, en donde los Estados están interesados principalmente en aumentar su seguridad con el objetivo de sobrevivir, lo cual resulta incompatible con otros Estados. Por último, se identifica de forma documentada cuales son los aspectos afectados en la seguridad de Israel a partir de la política exterior del gobierno de Mahmoud Ahmadinejad y cómo el Estado judío ha utilizado otras estrategias que anteriormente no había recurrido.

Avaliação de impacto do Programa de Modernização Tributária e da Gestão dos Setores Sociais Básicos (PMAT) na arrecadação de ISSQN e IPTU dos municípios, no período de 1999 a 2011

O objetivo deste trabalho é avaliar o impacto do Programa de Modernização da Administração Tributária e da Gestão dos Setores Sociais Básicos (PMAT), gerido pelo Banco Nacional de Desenvolvimento Econômico e Social (BNDES), na arrecadação tributária dos Municípios, no período de 1999 a 2011. Para tanto, utilizamos um modelo econométrico de dados em painel com estimador de efeitos fixos. As variáveis dependentes são os logs da arrecadação de ISSQN e IPTU, as variáveis explicativas são os desembolsos do BNDES e o PIB municipal desagregado. Realizamos regressões com dummies de tratamento e com o log dos desembolsos. Além realizar regressões com toda a amostra disponível, delimitamos a amostra do grupo de controle em dois subgrupos para tentar eliminar efeitos de tendências entre entidades. A primeira delimitação foi utilizar a amostra que realizou consultas ao banco de fomento e não obteve sucesso. A segunda delimitação foi a de municípios que possuem proximidade geográfica daqueles comtemplados pelo financiamento. Os resultados encontrados demonstram não haver significância estatística entre desembolsos realizados pelo BNDES e a trajetória da arrecadação dos tributos em análise na maior parte dos modelos utilizados. Apenas nas regressões com dados da amostra que realizou consulta ao BNDES, obteve-se significância estatística, ao nível de 5% para o tributo IPTU, no efeito acumulado ao longo do tempo.

Progress towards Elimination of HIV Mother-to-Child Transmission in the Dominican Republic from 1999 to 2011

In 1999, prevention of mother-to-child transmission (pMTCT) using antiretrovirals was introduced in the Dominican Republic (DR). Highly active antiretroviral therapy (HAART) was introduced for immunosuppressed persons in 2004 and for pMTCT in 2008. To assess progress towards MTCT elimination, data from requisitions for HIV nucleic acid amplification tests for diagnosis of HIV infection in perinatally exposed infants born in the DR from 1999 to 2011 were analyzed. The MTCT rate was 142/1,274 (11.1%) in 1999–2008 and 12/302 (4.0%) in 2009–2011 (), with a rate of 154/1,576 (9.8%) for both periods combined. This decline was associated with significant increases in the proportions of women who received prenatal HAART (from 12.3% to 67.9%) and infants who received exclusive formula feeding (from 76.3% to 86.1%) and declines in proportions of women who received no prenatal antiretrovirals (from 31.9% to 12.2%) or received only single-dose nevirapine (from 39.5% to 19.5%). In 2007, over 95% of DR pregnant women received prenatal care, HIV testing, and professionally attended delivery. However, only 58% of women in underserved sugarcane plantation communities (2007) and 76% in HIV sentinel surveillance hospitals (2003–2005) received their HIV test results. HIV-MTCT elimination is feasible but persistent lack of access to critical pMTCT measures must be addressed.

Periodontal outcomes and social, racial and gender inequalities in Brazil: a systematic review of the literature between 1999 and 2008

The objective of this study was to review the Brazilian epidemiologic literature on periodontal outcomes and socio-demographic factors, assessing bibliographic and methodological characteristics of this scientific production, as well as the consistency and statistical significance of the examined associations. A systematic review was carried out in six bibliographic sources. The review was limited to the period between 1999 and 2008, without any other type of restriction. Among the 410 papers identified, 29 were included in the review. An increasing number of articles, specifically in the last four years of study, was observed. However, there is a concentration of studies in the South and Southeast regions of Brazil, and many of them are not closely connected to theoretical formulations in the field. In spite of these shortcomings, the review findings corroborate the idea that poor socioeconomic conditions are associated with periodontal outcomes, as demonstrated primarily by income and schooling indicators.

Energy system contributions to the special judo fitness test

Purpose: This study investigated the energy system contributions of judo athletes to the Special Judo Fitness Test (SJFT). Methods: Fourteen male judo athletes performed the SJFT, which comprised three periods of judo activity (A = 15 s, B and C = 30 s) interspersed with 10 s rest intervals. During this test, one athlete threw two others positioned 6 m from each other using the ippon-seoi-nage technique. The fractions of the aerobic, anaerobic alactic and anaerobic lactic systems were calculated based on oxygen uptake, the fast component of excess postexercise oxygen uptake, and changes in net blood lactate, respectively. The contribution of the three energy systems was compared using a repeated measures analysis of variance and Bonferroni's multiple comparisons test. Compound symmetry, or sphericity, was determined by Mauchly's test. A level of significance of 5% (P < .05) was adopted in all analyses. Results: The alactic energy system presented a higher (F = 20.9; P < .001; power observed = 1.0) contribution (86.8 +/- 23.6 kJ; 42.3 +/- 5.9%) during the test when compared with both aerobic (57.1 +/- 11.3 kJ; 28.2 +/- 2.9%) and lactic (58.9 +/- 12.1 kJ; 29.5 +/- 6.2%) energy systems (P < .001 for both comparisons). Conclusions: The higher alactic contribution seems to be a consequence of the high-intensity efforts performed during the test, and its intermittent nature. Thus, when using the SJFT, coaches are evaluating mainly their athletes' anaerobic alactic system, which can be considered to be the most predominant system contributing to the actions (techniques) performed in the match.

Endurance in judogi grip strength tests: comparison between elite and non-elite judo players

Background and Study Aim: The ability to develop a strong grip and maintain it during a judo match has become an important element for judo athletes. Therefore, the purpose of this investigation was to examine differences between measurements of maximal isometric time on judogi pull-up, and number of repetitions during dynamic judogi pull-up. Material/Methods: The sample was composed by two groups: 16 high-level judo athletes from the male Brazilian National Team and 12 male state-level judo athletes, with at least one athlete per weight category. The tests were compared through analysis of co-variance (body mass as co-variable), followed by a post-hoc test (Scheffe). Significance level was set at 5%. Results: No difference was found in the isometric test: Brazilian Team: 35 +/- 18s; Regional: 39 +/- 14s. However, the Brazilian Team performed a high number of repetitions (12 +/- 5 rep) compared to regional group (9 +/- 4 rep) during the dynamic grip strength endurance test. Conclusions: Thus, dynamic grip strength endurance seems to be a discriminating variable between judo athletes, probably because judo combat involves many elbow extensions and flexions in order to avoid the opponent`s grip and to subdue them.

Reinterpreting the history of women's judo in Japan

This paper reassesses the role of women in judo in Japan, from its secluded and restricted beginnings in the late nineteenth century to the gradual changes in gender and social paradigms triggered by the influence of Western feminist struggle from the 1960s onwards. Judo has been considered in theory an inclusive martial art because its creator, Jigoro Kano, stressed safety, etiquette and moral teachings irrespective of age, size or gender of its adherents. However, the social and cultural environment in Japan has traditionally discriminated against women both outside and inside the dojo (training place). We treat this issue historically, considering the broader context of the Japanese social, political and cultural developments.

Acute effects and postactivation potentiation in the special judo fitness test

Miarka, B, Del Vecchio, FB, and Franchini, E. Acute effects and postactivation potentiation in the special judo fitness test. J Strength Cond Res 25(2): 427-431, 2011-The purpose of this study was to compare the acute short-term effects of (1) plyometric exercise, (2) combined strength and plyometric exercise (contrast), and (3) maximum strength performance in the Special Judo Fitness Test (SJFT). Eight male judo athletes (mean +/- SD, age, 19 +/- 1 years; body mass, 60.4 +/- 5 kg; height, 168.3 +/- 5.4 cm) took part in this study. Four different sessions were completed; each session had 1 type of intervention: (a) SJFT control, (b) plyometric exercises + SJFT, (c) maximum strength + SJFT, and (d) contrast + SJFT. The following variables were quantified: throws performed during series A, B, and C; total number of throws; heart rate immediately and 1 minute after the test; and test index. Significant differences were found in the number of throws during series A: the plyometric exercise (6.4 +/- 0.5 throws) was superior (p < 0.05) to the control condition (5.6 +/- 0.5 throws). Heart rate 1 minute after the SJFT was higher (p < 0.01) during the plyometric exercise (192 +/- 8 bpm) than during the contrast exercise (184 +/- 9 bpm). The contrast exercise (13.58 +/- 0.72) resulted in better index values than the control (14.67 +/- 1.30) and plyometric exercises (14.51 +/- 0.54). Thus, this study suggests that contrast and plyometric exercises performed before the SJFT can result in improvements in the test index and anaerobic power of judo athletes, respectively.

Pressupostos e significado do golpe de estado de 1998-1999 na Guiné-Bissau

RESUMO: O golpe de Estado de 1998-1999 na Guiné-Bissau é - entre outras razões - o resultado da difícil articulação e coabitação entre as principais racionalidades que afectam o xadrez sociopolítico guineense. De facto as racionalidades de tipo «weberianas», representadas maioritariamente pela população crioula, devido ao impacto da cultura colonial – o mimetismo cultural e político-económico nessa população -, não se adaptaram às racionalidades de tipo «tradicional» e estas por sua vez, não compreendem as primeiras. As práticas dos actores políticos das racionalidades de tipo «weberianas», dentro do aparelho de Estado confundiam-se com o próprio processo de construção e o funcionamento do Estado pós-colonial na Guiné De facto o Estado em referência tornou-se durante o segundo regime do PAIGC num simples instrumento político e económico a favor dos dirigentes daquele partido e da classe-Estado em geral em detrimento da população guineense sobretudo a da sociedade tradicional. E é também dentro desta lógica da difícil articulação e a coabitação de racionalidades entre actores guineenses que a suspensão do ex-Brigadeiro Ansumane Mané, das suas funções de chefe de Estado-maior das forças armadas guineenses deve ser analisada, explicada e entendida com a consequente ruptura político-militar. Certamente que a Guiné, como laboratório social, não se esgota neste trabalho, que apenas pretende abrir caminho para novas investigações. ABSTRACT: This study is focused on the analysis of the 1998-1999 «coup d’état» in Guiné as a denouncer of the difficulties in the construction of Guiné as a State and a Nation. The above mentioned coup d’état is, among other reasons, the result of the difficult articulation and cohabition among the main rationalities affecting the Guiné sociopolitical chess. The as-webeian rationalities, mainly represented by the creole population, on reproducing the colonial cultural, political and economic model, did not fit in the astraditional rationalities, which by their turn do not understand the former ones. The as-weberian practices of the main political agents within the state burocracy overlapped with the process of construction and the functioning of the post colonial state apparatus. During the second PAIGC regime the state becomes a mere political and economic instrument to favour the party leaders and the new emerging class of public workers, in detriment of the population, mainly the ones belonging to the traditional societies. It is against this sociopolitical background that the suspension of the ex-Brigadier Ansumane Mané from his functions as Chief Commander of the Armed Forces of Guiné, and the following military and political rupture, has to be analysed, explained and understood. Certainly, the study of Guiné as a social laboratory is not finished with the present research, which intended only to open the path to further researching.