Como el agua entre los dedos. Estudio de los impactos de un proyecto hidroeléctrico, y de las frágiles y débiles acciones colectivas en la defensa de un río: Caso Hidrosogamoso

La acción colectiva en el manejo y gobierno de los recursos de uso común (RUC) seguirá siendo uno de los asuntos que genera mayores controversias (especialmente cuando se trata de recursos naturales y procesos de gobernanza y gestión del agua), debido a los diversos enfoques que sobre el desarrollo se tienen. El presente estudio aborda el análisis de la acción colectiva en el manejo y gobierno de los recursos de uso común a partir del caso Hidrosogamoso en Santander. Además de ofrecer un análisis de los impactos ambientales, sociales y económicos, ventajas y efectos nocivos que puede tener un proyecto hidroeléctrico, se examinan algunos de los postulados básicos de la teoría de la acción colectiva y los RUC, con alguna alusión al enfoque de la bioeconomía. También se describe una de las experiencias comunitarias de autogobierno y preservación del río. Asimismo se estudia el contexto de interacción estratégica en la zona, en el conflicto entre quienes defienden el río y quienes abogan por el proyecto; se ubican las principales oportunidades políticas y aliados influyentes de los opositores durante la fase de construcción de la hidroeléctrica. Al final se insinúan posibles alternativas que podrían ayudar en la visibilización de las problemáticas generadas por el megaproyecto.

Diabetes relacionada a la fibrosis quística (DRFQ)

Importancia: el paciente con fibrosis quística después de las complicaciones gastrointestinales y pulmonares debe enfrentar otras comorbilidades como la diabetes relacionada a su condición . Dado el aumento en la esperanza de vida y el hecho de que virtualmente todas los pacientes con esta enfermedad pueden desarrollar alteración en el metabolismo de los carbohidratos, se requiere una sensibilización frente al tema que posibilite una detección temprana de esta entidad y un tratamiento óptimo que evite las complicaciones microvasculares e impacte entre otros el crecimiento pondo-estatural en pacientes en desarrollo y la función pulmonar. Objetivo : realizar una revisión actualizada de la literatura sobre la diabetes relacionada a la fibrosis quística, destacando las indicaciones de tamización y tratamiento. Conclusión : la FQ dentro de su abordaje requiere la detección temprana de la alteración del metabolismo de los carbohidratos con una prueba de tolerancia a la glucosa , el daño del islote pancreático , la disfunción inmune, la resistencia a la insulina, el estrés oxidativo entre otros elementos fisiopatológicos conllevan a un estado de depleción de insulina que producirán un efecto negativo microvascular así como a una reducción marcada de la función pulmonar, mayores tasa de infección e incremento de la mortalidad. La piedra angular del tratamiento en pacientes con o sin hiperglicemia es la insulina que mejora tanto el estado nutricional como la función pulmonar ; nuevos antidiabéticos orales con efecto incretinas y fármacos modificadores de la enfermedad se vislumbran como alternativas al corto plazo

Prevalence and functions of non-suicidal self-injury in Spanish adolescents

Resumen tomado de la publicaci??n

Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression

Virtually every mammalian cell, including cardiomyocytes, possesses an intrinsic circadian clock. The role of this transcriptionally based molecular mechanism in cardiovascular biology is poorly understood. We hypothesized that the circadian clock within the cardiomyocyte influences diurnal variations in myocardial biology. We, therefore, generated a cardiomyocyte-specific circadian clock mutant (CCM) mouse to test this hypothesis. At 12 wk of age, CCM mice exhibit normal myocardial contractile function in vivo, as assessed by echocardiography. Radiotelemetry studies reveal attenuation of heart rate diurnal variations and bradycardia in CCM mice (in the absence of conduction system abnormalities). Reduced heart rate persisted in CCM hearts perfused ex vivo in the working mode, highlighting the intrinsic nature of this phenotype. Wild-type, but not CCM, hearts exhibited a marked diurnal variation in responsiveness to an elevation in workload (80 mmHg plus 1 mu M epinephrine) ex vivo, with a greater increase in cardiac power and efficiency during the dark (active) phase vs. the light (inactive) phase. Moreover, myocardial oxygen consumption and fatty acid oxidation rates were increased, whereas cardiac efficiency was decreased, in CCM hearts. These observations were associated with no alterations in mitochondrial content or structure and modest mitochondrial dysfunction in CCM hearts. Gene expression microarray analysis identified 548 and 176 genes in atria and ventricles, respectively, whose normal diurnal expression patterns were altered in CCM mice. These studies suggest that the cardiomyocyte circadian clock influences myocardial contractile function, metabolism, and gene expression.

Kvinnors erfarenhet av postoperativ smärta och smärtlindring efter kejsarsnitt

Background: Many women experience high levels of pain after caesarean birth. Adequate postoperative pain treatment is important for the mother to be able to breastfeed, take care of the infant and experience a positive birth. Objective: The overall aim is to study women’s experience of postoperative pain and pain relief after caesarean birth. Method: A quantitative retrospective survey. Data were collected thru a questionnaire from Centralsjukhuset in Karlstad and Falu Larsarett in Sweden. Ninety-eight women participated in the study. Data was analysed with descriptive and comparative statistic. Result: Eighty percent of the women rated the pain with VAS = 4 during the first 24 hours post operative. Those who had to undergo acute caesarean birth rated significant higher levels of pain compared with those who had undergone planned caesarean birth. Despite high level of pain the women were satisfied with the pain relief they received. Both the ability to breastfeed and take care of the infant were affected by pain the first 24 hours post operative. Those who had undergone emergency caesarean birth experienced in greater extend the birth in a negative way. Conclusion: Postoperative pain affects the women’s ability to breastfeed and takes care of here infant. Adequate pain management is therefore important. The women who had to undergo emergency caesarean birth have a more negative birth experience. Midwifes have an important role to inform and support the women in processing here experience.

A dinâmica dos recursos comuns em Unidades de Conservação e Assentamentos Rurais no Amazonas: uma abordagem fuzzy set

A teoria de Garret Hardin intitulada “A tragédia dos comuns” apresenta a privatização e o controle governamental como saída para evitar o esgotamento dos recursos naturais. Entretanto, outros autores demonstraram que os usuários dos recursos podem apresentar eficientes formas de manejo, aliando o uso pelo homem à conservação da natureza. Esta tese analisa o uso de recursos comuns em Unidades de Conservação e Assentamentos Rurais de Uso Sustentável, localizadas no interflúvio Purus-Madeira, região Sul do Estado do Amazonas. A pergunta que norteou a hipótese da pesquisa foi: Diante das especificidades amazônicas e das regras impostas pelas políticas ambientais e agrárias na região, quais condições apresentam-se como necessárias e suficientes ao bom desempenho no uso de recursos comuns? A análise foi realizada por meio da combinação de três métodos: o método comparativo Qualitative Comparative Analysis (QCA), o método de análise institucional Institutional Analysis and Development (IAD) Framework e a lógica fuzzy. Operacionalmente, foram consideradas como variáveis independentes (X) os aspectos socioeconômicos, produtivos, ambientais e institucionais, partindo-se do pressuposto de que os programas governamentais destinados às Unidades devem apresentar melhorias nestes indicadores, refletindo por sua vez no bom desempenho no uso de recursos comuns (variável dependente Y) a partir deste desenho institucional. Os resultados confirmaram as hipóteses levantadas, afirmando-se que o bom desempenho no uso de recursos comuns, preconizado pelos critérios da sustentabilidade, somente pode ser alcançado mediante a combinação de um desempenho também satisfatório nas variáveis socioeconômicas, produtivas, institucionais e ambientais, apresentando-se estas variáveis como individualmente necessárias e conjuntamente suficientes para ocorrência deste fenômeno.

Arthur Cornwall Papers - Accession 289

The Arthur Cornwall Papers consist of personal, professional, genealogical and reference files of writer, musician, and historian Arthur Cornwall. The collection contains correspondence, radio scripts, feature articles, genealogical research notes, photographs, scrapbooks, and newspaper clippings. Of particular value are the genealogical files which contain exhaustive research relating to the Cornwall-Cornwell and Colvin families of Chester County. The collection includes genealogical research on many other Chester County families, such as Bennett, Coleman, Feaster, Hardin, Loving, Tims, Wylie, and Yongue. Included are many community histories.

Chester Genealogical Society Records - Accession 257 - M113 (145)

The Chester Genealogical Society Records consist of typescript material of writings and publications that covers mainly Chester County, SC history and genealogy from the 18th century to the 20th century. The collection includes information on covenanters, lists of Chester county American Civil War soldiers, Obadiah Hardin, Revolutionary War Lieut. Col. John R. Culp, Rev. Samuel McCreary, Mrs. M.A. Smith and the Smithton Lumber Co in Smithton, Arkansas, the Kulp family, Matthew Elder, Jr., Rev. Josiah Henson, the Gaston family, the Murphy family, Confederate Capt. G.L. Strait’s Company-6th regiment, Company B during the American Civil War, the McClure family and Revolutionary War Capt. John McClure, and recollections of Chester, South Carolina.

“Species Pollution” in Florida: A Cross-Section of Invasive Vertebrate Issues and Management Responses

The state of Florida as among the two worst invasive species problems in the USA. Besides the sheer numbers of established exotic species in Florida, many present novel difficulties for management, or have other characteristics making effective management extremely challenging. Moreover, initiation of management action requires more than recognition by experts that a potentially harmful species has become established. It also requires the political will along with concomitant resources and appropriate personnel to develop effective methods and apply them. We illustrate various aspects of the situation in Florida with examples of invasive vertebrates, the problems they pose(d), and management approaches to the problems.

The tragedy of the commons in evolutionary biology

Garrett Hardin's tragedy of the commons is an analogy that shows how individuals driven by self-interest can end up destroying the resource upon which they all depend. The proposed solutions for humans rely on highly advanced skills such as negotiation, which raises the question of how non-human organisms manage to resolve similar tragedies. In recent years, this question has promoted evolutionary biologists to apply the tragedy of the commons to a wide range of biological systems. Here, we provide tools to categorize different types of tragedy and review different mechanisms, including kinship, policing and diminishing returns that can resolve conflicts that could otherwise end in tragedy. A central open question, however, is how often biological systems are able to resolve these scenarios rather than drive themselves extinct through individual-level selection favouring self-interested behaviours.

Underground Stratigraphy of Montana

The purpose of this thesis is to study the subsurface stratigraphy of the state of Montana from information acquired from well logs, composite logs, and measured sections. Underground stratigraphy is important for the intelligent prospecting for oil, gas, or water. A knowledge of the strata beneath us can be gathered only by measurements of numerous outcrops or by deep drilling with careful sampling or logging of the formations passed through.

Upper Cretaceous Sediment in Montana

Cretaceous sediments in Montana record events during a period of unusual geologic interest. After a long period of extensive submergence of the area during Jurassic time, came a period of varying continental and marine deposition with consequent variations in the types of sediments laid down. A study of these variations, their extent, and their cause has been the primary object of this thesis.

Simulation of Drosophila circadian oscillations, mutations, and light responses by a model with VRI, PDP-1, and CLK.

A model of Drosophila circadian rhythm generation was developed to represent feedback loops based on transcriptional regulation of per, Clk (dclock), Pdp-1, and vri (vrille). The model postulates that histone acetylation kinetics make transcriptional activation a nonlinear function of [CLK]. Such a nonlinearity is essential to simulate robust circadian oscillations of transcription in our model and in previous models. Simulations suggest that two positive feedback loops involving Clk are not essential for oscillations, because oscillations of [PER] were preserved when Clk, vri, or Pdp-1 expression was fixed. However, eliminating positive feedback by fixing vri expression altered the oscillation period. Eliminating the negative feedback loop in which PER represses per expression abolished oscillations. Simulations of per or Clk null mutations, of per overexpression, and of vri, Clk, or Pdp-1 heterozygous null mutations altered model behavior in ways similar to experimental data. The model simulated a photic phase-response curve resembling experimental curves, and oscillations entrained to simulated light-dark cycles. Temperature compensation of oscillation period could be simulated if temperature elevation slowed PER nuclear entry or PER phosphorylation. The model makes experimental predictions, some of which could be tested in transgenic Drosophila.

Children's Perceptions of Male and Female Athletes as Presented in Sports Illustrated for Kids

Despite gains made by Title IX in the past 36 years, including increased female participation in high school and collegiate sport, there is evidence that gender equity in sport is not fully achieved. Researchers target the media because they tend to shape social values and disseminate information to the masses (Kane, 1978, in Fink & Kensicki, 2002). As sports become more pervasive, framing theory has become particularly relevant. The purpose of this study is to build on the Hardin et al. (2002) study by examining the relationship among media sports coverage, gender equity in sport and the perceptions young sports fans begin to form about gender and sport based on media consumption. The researcher hypothesized that since women face discrimination in sport starting from the time that they choose to participate, children will perceive male athletes and their sports as more legitimate. Additionally, the media play a major role in shaping the views of audiences, so the way that they represent male and female athletes, including juxtaposing them, may have an impact on children. The researcher conducted a content analysis of 24 Sports Illustrated for Kids issues from 1996 to 1999 and 24 issues from 2006 to 2007. The researcher analyzed the content of photographs (N=3219) and of headlines (N=762) by using the definitions determined by Hardin et al. (2002). We found that there is a disproportionate amount of coverage devoted to male athletes and that the discrepancy between media representation between men and women in sport has grown since the mid-1990s. This study also includes a focus group conducted with three children from a community swimming program in a northeastern town and found that those children were acutely aware of the differences between men and women in sport based on the discussion. The researcher does not attempt to find a causal relationship between these children’s perceptions and the way media represents them, but rather uses the focus group to complement the content analysis. As children become sports consumers in later life, future research exploring the relationship between children’s perceptions and the media’s representations need to be done before causality and the significance of media effects are determined.

Cytokinesis and Midzone Microtubule Organization in Caenorhabditis elegans Require the Kinesin-like Protein ZEN-4

Members of the MKLP1 subfamily of kinesin motor proteins localize to the equatorial region of the spindle midzone and are capable of bundling antiparallel microtubules in vitro. Despite these intriguing characteristics, it is unclear what role these kinesins play in dividing cells, particularly within the context of a developing embryo. Here, we report the identification of a null allele of zen-4, an MKLP1 homologue in the nematode Caenorhabditis elegans, and demonstrate that ZEN-4 is essential for cytokinesis. Embryos deprived of ZEN-4 form multinucleate single-celled embryos as they continue to cycle through mitosis but fail to complete cell division. Initiation of the cytokinetic furrow occurs at the normal time and place, but furrow propagation halts prematurely. Time-lapse recordings and microtubule staining reveal that the cytokinesis defect is preceded by the dissociation of the midzone microtubules. We show that ZEN-4 protein localizes to the spindle midzone during anaphase and persists at the midbody region throughout cytokinesis. We propose that ZEN-4 directly cross-links the midzone microtubules and suggest that these microtubules are required for the completion of cytokinesis.