999 resultados para AC-1
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In this paper we develop and numerically explore the modeling heuristic of using saturation attempt probabilities as state dependent attempt probabilities in an IEEE 802.11e infrastructure network carrying packet telephone calls and TCP controlled file downloads, using enhanced distributed channel access (EDCA). We build upon the fixed point analysis and performance insights. When there are a certain number of nodes of each class contending for the channel (i.e., have nonempty queues), then their attempt probabilities are taken to be those obtained from saturation analysis for that number of nodes. Then we model the system queue dynamics at the network nodes. With the proposed heuristic, the system evolution at channel slot boundaries becomes a Markov renewal process, and regenerative analysis yields the desired performance measures. The results obtained from this approach match well with ns2 simulations. We find that, with the default IEEE 802.11e EDCA parameters for AC 1 and AC 3, the voice call capacity decreases if even one file download is initiated by some station. Subsequently, reducing the voice calls increases the file download capacity almost linearly (by 1/3 Mbps per voice call for the 11 Mbps PHY)
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本论文从内容上可以分为两大部分:第一部分:对近球形核~(143)Pm高自旋态进行的在束γ研究。这一部分是本文的重点。利用能量为82和90 MeV的~(19)F束流,通过融合蒸发反应~(128)Te (~(19)F,4nγ) ~(143)Pm布局~(143)Pm的高自旋态。利用联合在束装置(JIBGE)的10套带BGO反康的HPGe探测器进行了标准在束γ谱学测量,包括γ射线的激发函数、γ单谱、γ-γ-t符合谱以及DCO测量。在已有工作的基础上,建立了~(143)Pm激发能高达10.5 MeV,自旋约为(61/2)h的高自旋态能级结构。观测到了28条新的跃迁能级和48条新的γ射线。对两个已知的同质异能态寿命进行了提取,并在8 MeV激发能附近进行了高自旋态同质异能态的搜索。以~(142)Nd,~(144)Sm为核实,用零级弱耦合模型对~(143)Pm的晕态能级结构进行了定量的解释。计算表明,直到激发能Ex = 6.77 MeV,自旋宇称J~π = (37/2~+)的晕态能级都可以用弱耦合模型进行很好的解释。但是,对于更高激发能的能级,组态情况要复杂的多,有出现N = 82中子闭壳打破的可能。同时,利用大基壳模型OXBASH程序对其能级结构进行了计算和讨论,其结果支持弱耦合模型的假设。第二部分:利用中能重离子的多核子转移反应,(~(186)W-2p + 2n),(~(238)U-2p + 2n)对丰中子核~(186)Hf和~(238)Th进行了合成和鉴别。测量它们的半衰期分别为(2.6 ± 1.2) min和 (9.4 ± 2.0) min,与用质子一中子准粒子随机相近似方法的预言值是相符的。同时,对β延发裂变先驱核~(230)Ac进行了实验研究。观测到了它的两个裂变事件,得到~(230)Acβ延发裂变几率为(1.19 ± 0.85) * 10~(-8)。从而使~(230)Ac成为世界上第一种被确认了的基态β延发裂变先驱核。
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本文研究了典型有毒赤潮藻——亚历山大藻(Alexandrium)对海湾扇贝(Argopecten irradians Lamarck)、文蛤(Meretrix meretrix Linnaeus)和太平洋牡蛎(Ostrea gigas Thunberg)受精卵孵化的影响和致毒机制以及对蒙古裸腹溞(Moina mongolica Daday)生命活动的影响。此外,还针对我国赤潮发生特点,模拟研究了我国东海大规模赤潮对菲律宾蛤仔(Ruditapes philippinarum (Adams et Reeve))受精卵孵化和蒙古裸腹溞种群数量的影响。 结果发现:8株产PSP毒素的亚历山大藻:塔玛亚历山大藻( ATHK, AT5-1, AT5-3, ATCI02, ATCI03),链状亚历山大藻, A. lusitanicum、微小亚历山大藻和2株不产PSP毒素的相关亚历山藻(AC-1, AS-1)对海湾扇贝受精卵的孵化均有显著抑制作用,说明在亚历山大藻属中,这种抑制作用具有一定的普遍性,并与PSP毒素的产生无直接关系,表明存在非PSP毒素的其它毒性物质。一种PSP标准毒素STX也没有这种抑制作用,进一步证明该抑制作用与PSP毒素不直接相关。 相关亚历山大藻AC-1对海湾扇贝、文蛤和太平洋牡蛎受精卵孵化的有显著的毒害作用,其藻液、重悬液、去藻液和内容物均显著影响受精卵的孵化。相关亚历山大藻AC-1对海湾扇贝、文蛤和太平洋牡蛎担轮幼虫细胞的超微结构有显著破坏作用,破坏膜结构和胞内结构,影响细胞内的功能器官如溶酶体的稳定性,使卵黄颗粒萎缩变形;对文蛤和太平洋牡蛎的受精卵显示出极强的毒害作用: 3000cells•ml-1时,使二者胚胎完全溶掉消失;在2000cells•ml-1的藻液中培养2h后,担轮幼虫的外膜发生溶解,整个幼体呈葡萄串样。相关亚历山大藻AC-1产生的这种毒性物质可能对贝类胚胎细胞的结构和功能有影响。 亚历山大藻对蒙古裸腹溞的毒性效应与不同藻种/藻株密切有关:塔玛亚历山大藻(AT-6, ATCI02)、链状亚历山大藻、A. lusitanicum和微小亚历山大藻不影响蒙古裸腹溞的存活,而塔玛亚历山大藻(ATHK、ATCI03和AT5-1)和相关亚历山大藻(AC-1, AS-1)有显著影响。蒙古裸腹溞能摄食塔玛亚历山大藻(AT-6, ATHK, ATCI02, ATCI03, AT5-1),链状亚历山大藻, A. lusitanicum和微小亚历山大藻,很少或基本不摄食相关亚历山大藻。亚历山大藻影响蒙古裸腹溞的RNA/DNA比值和蛋白质含量以及Na+,K+-ATP酶活性。相关亚历山大藻AC-1对蒙古裸腹溞的存活有极强的毒性作用,藻液、重悬液、内容物和碎片均有显著影响;即使与3×106cells•ml-1小球藻混合,10和50cells•ml-1的相关亚历山大藻AC-1仍能使蒙古裸腹溞的产幼数和存活时间显著下降。亚历山大藻对蒙古裸腹溞生命活动的影响不仅与PSP毒素有关,还与非PSP毒素有关;蒙古裸腹溞可能也是研究有害藻急性和慢性毒性的一种理想生物。 应用菲律宾蛤仔胚胎和蒙古裸腹溞评价我国东海特大规模赤潮对海洋生物资源的潜在危害时发现:单种链状亚历山大藻对菲律宾蛤仔受精卵的孵化和蒙古裸腹溞的种群增长均有显著不利影响;单种东海原甲藻(1~10×104cells•ml-1)对菲律宾蛤仔受精卵的孵化没有影响;较低密度的东海原甲藻能维持蒙古裸腹溞(2~5×104cells•ml-1)的种群增长;较高密度的东海原甲藻对蒙古裸腹溞(10×104cells•ml-1)种群有显著的抑制作用。两种藻以赤潮密度混合后,适当密度的东海原甲藻能在一定程度上减轻链状亚历山大藻对菲律宾蛤仔受精卵和蒙古裸腹溞的毒性。可见,东海连年爆发的大规模赤潮不仅对浮游生态系统有不利影响,若同时爆发亚历山大藻赤潮,则对海洋浮游生态系统和贝类资源的恢复产生更加不利的影响。
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本文以一株不产PSP毒素的相关亚历山大藻(AC-1)为对象,研究了该藻株对褶皱臂尾轮虫、卤虫、黑褐新糠虾急性毒性效应和对糠虾的慢性毒性影响,同时对AFT毒素成分进行了研究,研究结果如下: 通过相关亚历山大藻(AC-1)对褶皱臂尾轮虫、卤虫、黑褐新糠虾的急性毒性影响研究,发现随着相关亚历山大藻(AC-1)密度的升高,轮虫、卤虫、糠虾的存活率逐渐降低,其96hLC50分别为:1500cells/ml,90cells/ml,5000cells/ml。比较研究三种生物对相关亚历山大藻(AC-1)敏感性可以看出,三种生物对该藻的敏感性顺序为:卤虫>轮虫>糠虾。 相关亚历山大藻(AC-1)对黑褐新糠虾的生长及种群繁殖有显著影响,我们发现在密度为50cells/ml藻液中,糠虾的繁殖就受到了不利影响。实验进行到63d结束时,糠虾日最高产虾数、总产幼虾数、总产虾天数都明显减少,初次产虾时间推迟,繁殖中断增加。且该藻对黑褐新糠虾亲虾的存活、生长也有一定的影响,糠虾亲虾的存活率为对照的71%,而体长和体重分别为对照组的87.3%和97.8%,但差异尚不显著(P>0.05)。 研究相关亚历山大藻(AC-1)各组分的毒性(藻液、藻细胞重悬液、藻细胞培养过滤液、内容物),发现藻液和藻细胞重悬液对褶皱臂尾轮虫种群数量及轮虫、卤虫、糠虾的存活率均有显著影响,表明相关亚历山大藻活体藻细胞的毒性最强。过滤液和内容物也显著降低了轮虫和卤虫的存活率,其对糠虾也有影响,但不显著,表明AFT毒素可能来源于细胞内,能分泌到细胞培养液中。 研究相关亚历山大藻(AC-1)AFT毒素的热稳定性、酸碱稳定性、去蛋白组分毒性、分子量范围、极性、多糖组分鉴定,表明AFT毒素为极性较强的多糖类物质,对热和酸碱是稳定的,其分子量范围在5K~50K之间。 以上结果表明相关亚历山大藻(AC-1)虽然不产生PSP毒素,但能产生极性多糖类毒素,对甲壳类等浮游动物的种群数量和资源补充产生不利影响。本研究为以后进一步研究AFT毒素的作用机制和毒素的化学结构奠定了基础,为全面评价亚历山大藻赤潮的危害提供了科学依据。
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2003年6月30日~9月4日,利用密闭箱-气相色谱法,对发育于不同水分状况下的灌丛草甸(GC)、矮嵩草草甸(AC)、藏嵩草草甸(ZC)和季节性湿地(SD)的CH4释放速率进行了比较研究.结果表明,观测期间,季节性湿地处于淹水状态,其它三种土壤平均水分含量分别为39.6%(GC)、38.4%(AC)、65.9%(ZC),而CH4平均释放速率分别为-0.031±0.030(GC)、-0.026±0.018(AC)、1.103±0.240(ZC)和6.922±4.598 mg•m-2•h-1(SD),随着土壤水分含量的增加,高寒草地土壤CH4释放由吸收转为排放,表现出与土壤湿度很好的一致性.矮嵩草草甸不同处理CH4吸收强度AC<AJ<AL,它们之间的差异除与土壤水分有关,还可能与处理引起的CH4传输途径不同有关.实验期间,矮嵩草草甸和灌丛草甸土壤-植物系统分别吸收CH438.69和46.13 mg•m-2,是大气温室气体CH4的弱汇,藏嵩草草甸和季节性湿地则是大气温室气体CH4的源,分别排放CH4 1.641和10.30 g•m-2.
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PURPOSE: To characterize the biophysical, pharmacologic, and functional properties of the Ca(2+)-activated Cl(-) current in retinal arteriolar myocytes. METHODS: Whole-cell perforated patch-clamp recordings were made from myocytes within intact isolated arteriolar segments. Arteriolar tone was assessed using pressure myography. RESULTS: Depolarizing of voltage steps to -40 mV and greater activated an L-type Ca(2+) current (I(Ca(L))) that was followed by a sustained current. Large tail currents (I(tail)) were observed on stepping back to -80 mV. The sustained current and I(tail) reversed close to 0 mV in symmetrical Cl(-) concentrations. The ion selectivity sequence for I(tail) was I(-)> Cl(-)> glucuronate. Outward I(tail) was sensitive to the Cl(-) channel blockers 9-anthracene-carboxylic acid (9-AC; 1 mM), 4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid (SITS; 1 mM), and disodium 4,4'-diisothiocyanatostilbene-2,2'-disulfonate (DIDS; 1 mM), but only DIDS produced a substantial (78%) block of inward tail currents at -100 mV. I(tail) was decreased in magnitude when the normal bathing medium was substituted with Ca(2+)-free solution or if I(Ca(L)) was inhibited by 1 microM nimodipine. Caffeine (10 mM) produced large transient currents that reversed close to the Cl(-) equilibrium potential and were blocked by 1 mM DIDS or 100 microM tetracaine. DIDS had no effect on basal vascular tone in pressurized arterioles but dramatically reduced the level of vasoconstriction observed in the presence of 10 nM endothelin-1. CONCLUSIONS: Retinal arteriolar myocytes have I(Cl(Ca)), which may be activated by Ca(2+) entry through L-type Ca(2+) channels or Ca(2+) release from intracellular stores. This current appears to contribute to agonist-induced retinal vasoconstriction.
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Título del encuentro: 'Las TICs en el aula de ELE', organizado por el Instituto Cervantes de Nápoles
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The isotherms of adsorption of CuX2 (X = Cl-, Br, ClO4-,) by silica gel chemically modified with thiazolidine-2-thione were studied in acetone (ac) and ethanol (eth) solutions at 25 degrees C. The following equilibrium constants (in 1 mol(-1)) were determined: a) CuCl2, 1.9 x 10(3) (ac), 1.6 x 10(3) (eth); b) CuBr2, 1.7 x 10(3) (ac), 1.2 x 10(3) (eth); c) Cu(ClO4)(2), 1.1 x 10(3) (ac), 1.0 x 10(3) (eth). The electron spin resonance spectra of the surface complexes indicate a tetragonal distorted structure in the case of lower degrees of metal loading on the chemically modified surface. The d-d electronic transition spectra show that for the ClO4- complex, the peak of absorption did not change for any degree of metal loading, and for Cl- and Br complexes, the peak maxima shift to higher energy with lower metal loading.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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As anemias hereditárias, em especial as talassemias e hemoglobinas (Hb) variantes, são as mais comuns das alterações genéticas humanas; sua freqüência na população brasileira é muito variável, dependendo dos grupos raciais formadores de cada região. O povoamento de Goiás, que teve início logo após o seu descobrimento, em 1726, motivado pela procura de ouro, foi composto principalmente por portugueses e escravos africanos, contexto que favoreceu a mestiçagem entre eles. Considerando que esses povos apresentam genes para as hemoglobinas anormais com freqüências variadas, é esperado que se encontrem essas alterações genéticas na nossa população. O objetivo deste trabalho foi avaliar a prevalência de talassemias e hemoglobinas variantes na população de Goiás. Para isso a casuística foi composta por 404 alunos participantes dos diversos cursos da Universidade Católica de Goiás (UCG), oriundos de 55 cidades do estado de Goiás. A prevalência de anemia hereditária por talassemias e hemoglobinas variantes em Goiás foi de 10,1%, cuja ordem decrescente foi a seguinte: talassemia alfa heterozigótica (5,2%), heterozigose para hemoglobina S (Hb AS) (2,2%), heterozigose para hemoglobina C (Hb AC) (1%), talassemia beta menor (0,7%), associação entre talassemia alfa e heterozigose para Hb S (0,5%), associação entre talassemia alfa e heterozigose para Hb C (0,3%) e heterozigose para hemoglobina D (Hb AD) (0,3%). Nenhum caso de homozigose foi encontrado no presente estudo. Este trabalho demonstrou a dispersão dos genes para Hb S, Hb C e Hb D, bem como de talassemias alfa e beta em uma população do estado de Goiás. Por essa razão, concluímos que é importante realizar programas com maior abrangência da população para estudo da epidemiologia das talassemias e hemoglobinas variantes no estado de Goiás.
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Well-fitted dentures prevent hyperplasic lesions, provide chewing efficiency and promote patient's comfort. Several factors may affect final adaptation of dentures, as the type of the acrylic resin, the flask cooling procedure and the water uptake. This investigation evaluated the effect of water storage and two different cooling procedures [bench cooling (BC) for 2 h; running water (RW) at 20 degreesC for 45 min] on the final adaptation of denture bases. A heat-cured acrylic resin (CL, Classico, Classico Artigos Odontologicos) and two microwave-cured acrylic resins [Acron MC, (AC) GC Dent. Ind. Corp.; Onda Cryl (OC), Classico Artigos Odontologicos] were used to make the bases. Adaptation was assessed by measuring the weight of an intervening layer of silicone impression material between the base and the master die. Data was submitted to ANOVA and Tukey's test (0.05). The following means were found: (BC) CL=0.72 +/- 0.03 a; AC=0.70 +/- 0.03 b; OC=0.76 +/- 0.04 c//(RW) CL= 1.00 +/- 0.11 a; AC=1.00 +/- 0.12 a; OC=0.95 +/- 0.10 a. Different labels join groups that are not statistically different (P > 0.05). Comparisons are made among groups submitted to the same cooling procedure (BC or RW). The conclusions are: interaction of type of material and cooling procedure had a statistically significant effect on the final adaptation of the denture bases (P < 0.05); water storage was not detected as a source of variance (P > 0.05) on the final adaptation.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Consideraciones que afectan el trabajo futuro de la Comisión (Nota del Secretario Ejecutivo Adjunto)