997 resultados para humain augmenté


Relevância:

20.00% 20.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

This study tested the hypothesis derived from social pain theory (MacDonald & Leary, 2005) that pain affect serves as a signal of perceived social exclusion. Participants ranging in experience of persistent physical pain completed measures of pain affect, anxious and avoidant attachment, anxiety, and depression. Higher levels of pain affect were found to relate to higher levels of anxious, but not avoidant, attachment. Further, anxious attachment partially mediated the relation between pain affect and emotional distress. These data support the conclusion that one reason individuals with persistent pain experience anxiety and depression is because of heightened concerns over rejection. The data also support the conclusion that anxious attachment is more strongly related to the fight-flight-freezing system than avoidant attachment.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Fracture healing is a complex process regulated by numerous growth and adhesive factors expressed at specific stages during healing. The naturally occurring, cell surface-expressed sugar, heparan sulfate (HS), is known to bind to and potentiate the effects of many classes of growth factors, and as such, may be a potential candidate therapy for enhancing bone repair. This study investigated the local application of bone-derived HS in the repair of rat femoral fractures. After 2 weeks, there was a significant increase in the callus size of rats administered with 5 mu g HS compared to the control and 50 mu g HS groups, presumably due to increased trabecular bone volume rather than increased cartilage production. In addition, 5 mu g HS increased the expression of ALP, Runx2, FGF-1, IGF-II, TGF-beta 1, and VEGF. It is hypothesized that these increases resulted from changes in HS-mediated receptor/ligand interactions that increase local growth factor production to augment bone formation. The findings of this study demonstrate the anabolic potential of HS in bone repair by recruiting and enhancing the production of endogenous growth factors at the site of injury. (c) 2006 Orthopaedic Research Society.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

More information is now readily available to computer users than at any time in human history; however, much of this information is often inaccessible to people with blindness or low-vision, for whom information must be presented non-visually. Currently, screen readers are able to verbalize on-screen text using text-to-speech (TTS) synthesis; however, much of this vocalization is inadequate for browsing the Internet. An auditory interface that incorporates auditory-spatial orientation was created and tested. For information that can be structured as a two-dimensional table, links can be semantically grouped as cells in a row within an auditory table, which provides a consistent structure for auditory navigation. An auditory display prototype was tested.^ Sixteen legally blind subjects participated in this research study. Results demonstrated that stereo panning was an effective technique for audio-spatially orienting non-visual navigation in a five-row, six-column HTML table as compared to a centered, stationary synthesized voice. These results were based on measuring the time- to-target (TTT), or the amount of time elapsed from the first prompting to the selection of each tabular link. Preliminary analysis of the TTT values recorded during the experiment showed that the populations did not conform to the ANOVA requirements of normality and equality of variances. Therefore, the data were transformed using the natural logarithm. The repeated-measures two-factor ANOVA results show that the logarithmically-transformed TTTs were significantly affected by the tonal variation method, F(1,15) = 6.194, p= 0.025. Similarly, the results show that the logarithmically transformed TTTs were marginally affected by the stereo spatialization method, F(1,15) = 4.240, p=0.057. The results show that the logarithmically transformed TTTs were not significantly affected by the interaction of both methods, F(1,15) = 1.381, p=0.258. These results suggest that some confusion may be caused in the subject when employing both of these methods simultaneously. The significant effect of tonal variation indicates that the effect is actually increasing the average TTT. In other words, the presence of preceding tones increases task completion time on average. The marginally-significant effect of stereo spatialization decreases the average log(TTT) from 2.405 to 2.264.^

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Mémoire numérisé par la Direction des bibliothèques de l'Université de Montréal.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Thèse numérisée par la Direction des bibliothèques de l'Université de Montréal.