Towards better health outcomes - What role for pharmaceutical innovation? EPC Policy Brief, 10 December 2015

From the current refugee crisis to ageing populations, and from rising healthcare prices to patients’ rising expectations: demands on European health systems continue to increase. Delivering health efficiently and ensuring the long-term sustainability of healthcare in the face of reduced public budgets requires new thinking – and there is a role for pharmaceuticals as well. Building on the series of discussions organised under Transformations, this Policy Brief focuses on the specific role of medicines and pharmaceutical innovation in improving health outcomes. It considers the state of play of drug innovation, from the development to the deployment of medicines, and the measures needed to make it deliver more for society and the economy, while ensuring that patients in Europe can have access to innovative and safe solutions.

Federal industrial innovation policy: review of congressional and task force activity. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Multinational activities of major U.S. automotive producers. Volume IV - a preliminary evaluation of technology innovation and transfer. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Recent international activity in cooperative vehicle-highway automation systems /

This report summarizes the current state of the art in cooperative vehicle-highway automation systems in Europe and Asia based on a series of meetings, demonstrations, and site visits, combined with the results of literature review. This review covers systems that provide drivers with a range of automation capabilities, from driver assistance to fully automated driving, with an emphasis on cooperative systems that involve active exchanges of information between the vehicles and the roadside and among separate vehicles. The trends in development and deployment of these systems are examined by country, and the similarities and differences relative to the U.S. situation are noted, leading toward recommendations for future U.S. action. The Literature Review on Recent International Activity in Cooperative Vehicle-Highway Automation Systems is published separately as FHWA-HRT-13-025.

Literature review on recent international activity in cooperative vehicle-highway automation systems /

This literature review supports the report, Recent International Activity in Cooperative Vehicle-Highway Automation Systems. It reviews the published literature in English dating from 2007 or later about non-U.S.-based work on cooperative vehicle-highway automation systems. This review covers work performed in Europe and Japan, with application to transit buses, heavy trucks, and passenger cars. In addition to fully automated driving of the vehicles (without human intervention), it also covers partial automation systems, which automate subsets of the total driving process. Recent International Activity in Cooperative Vehicle Highway Automation Systems is published separately as FHWA-HRT-12-033.

Transportation innovation in the states: national contest entries for 1988.

Mode of access: Internet.

Case study of the innovation process characterizing the development of the three-way catalytic converter system. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Department of Transportation's Intelligent transportation systems (ITS) projects book.

Mode of access: Internet.

The development and introduction of the automotive turbocharger: a case of innovation in response to fuel economy regulation. Final report.

National Highway Traffic Safety Administration, Office of Research and Development, Washington, D.C.

Advanced public transportation systems : the state of the art : update 2000 /

"December 2000"--P. [4] of cover.

Ethics and health systems research in 'post'-conflict situations

Although considerable attention has been given to ethical issues related to clinical research in developing countries, in particular related to HIV therapy, there has been limited focus on health systems research, despite its increasing importance in the light of current trends in development assistance. This paper examines ethical issues related to health systems research in 'post'-conflict situations, addressing both generic issues for developing countries and those issues specific to 'post'-conflict societies, citing examples from the author's Cambodian experience. It argues that the destruction of health infrastructure results in a loss of structures and processes that would otherwise protect prospective research subjects who are part of vulnerable populations. It identifies the growth of health systems research as part of a trend towards sectoral and programmatic development assistance, the emergence of 'knowledge generation' as a form of research linked to development, and the potential for conflict where multilateral and bilateral donors are both primary funders and users of health systems research. It also examines the position of the health system researcher in relation to the sponsors of this research, and the health system being analysed.

Institutional governance systems and variations in national competitive advantage: An integrative framework

Creating competitive industries has become one of the key tasks of governments. Different adaptation outcomes in industries across nations cannot be accounted for fully simply by an emphasis on firm-level capabilities, market-driven policies, or state-level policies. We propose an integrative framework that draws on both the strategic management and political economy literature to explain variations in national industrial competitiveness.. We discuss differences with respect to institutional characteristics and capabilities, competitive outcomes, conditions of best fit, and who bears the cost of industry adaptation.

Why is economics not a complex systems science?

The article argues that economics will have to become a complex systems science before economists can comfortably incorporate institutionalist and evolutionary economics into mainstream theory. The article compares the complex adaptive system of John Foster with that of standard economic theory and illustrates the difference through an examination of familiar production function. The place of neoclassical, Keynesian economics in complex systems is considered. The article concludes that convincing, multiple models have been made possible by the increase in widely available computing power available.

An object-orient designed FDTD simulator: Applications to high field systems

An object-oriented finite-difference time-domain (FDTD) simulator has been developed for electromagnetic study and design applications in Magnetic Resonance Imaging. It is aimed to be a complete FDTD model of an MRI system including all high and low-frequency field generating units and electrical models of the patient. The design method is described and MRI-based numerical examples are presented to illustrate the function of the numerical solver, particular emphasis is placed on high field studies.