Controversia della concezione della beata Vergine Maria /

Mode of access: Internet.

Herrn Veit Ludwigs von Seckendorff, Churf. Brandenb. ... Politische und moralische Discurse über M. Annæi Lucani dreyhundert auserlesen Lehrreiche Sprüche und dessen heroische Gedichte genannt Pharsalia : auf eine sonderbare neue Manier ins Deutsche gebracht und dem Lateinischen auf iedes Blatt gegen über gesetzt nebst beygefügter Erklärung derer dunckeln und schweren Redens-Art auch nötigem Register.

Includes index.

Illegal immigration : INS overstay estimation methods need improvement : report to the Chairman, Subcommittee on Immigration, Committee on the Judiciary, U.S. Senate /

"B-261245"--P. 1.

Draft supplemental programmatic environmental impact statement for INS and JTF-6 activities /

"March 1999."

Die aelteste astronomische Schrift des Maimonides : aus zwei Manuscripten der National-Bibliothek in Paris, bezeichnet: Fonds hébreu No. 1058 und No. 1061 : zum ersten Male ins Deutsche uebertragen mit sachlichen Anmerkungen, sowie einem Vorworte versehen.

Thesis (doctoral)--Friedrich-Alexanders-Universitat Erlangen.

Das Angeblich von rāmānuja verfasste vedāntatattvasāra mit einer Einleitung und Anmerkungen Herausgegeben und ins deutsche Übertragen /

Thesis (doctoral)--Universität Leipzig, 1906.

Musikalische Reise ins Land der Vergangenheit /

Mode of access: Internet.

Lug ins Land.

At head of title: Siebenie Libesgade deutscher Hochscüler.

Actividade dramática de Gil Vicente : & "Farsa de Inês Pereira" (anotada)

por Marques Braga

The ins and outs of transcriptional control: nucleocytoplasmic shuttling in development and disease

Recent findings relating to SOX transcription factors indicate that defects in organogenesis can be caused not only by impairment of the biochemical properties of transcription factors but also, in some cases, by deficient nuclear import. In addition, experimentally interfering with the nuclear export signals of some SOX factors has now been found to cause developmental defects. Controlling the balance of nuclear import and export might be a common means by which transcription factor activity can be regulated during development, and defects in these processes might underlie a broader spectrum of inherited developmental disorders.

The ins and outs of E-cadherin trafficking

One way of controlling the activity of E-cadherin - a protein that is, simultaneously, a major cell-adhesion molecule, a powerful tumour suppressor, a determinant of cell polarity and a partner to the potent catenin signalling molecules - is to keep it on the move. During the past two decades, many insights into the fundamental role of E-cadherin in these processes have been garnered. Studies during the past five years have begun to reveal the importance of intracellular trafficking as a means of regulating the functions of E-cadherin. E-cadherin is trafficked to and from the cell surface by exocytic and multiple endocytic pathways. In this article, we survey the vesicle-trafficking machinery that is responsible for the sorting, transport, actin association and vesicle targeting of E-cadherin to regulate its movement and function during growth and development and, possibly, in cancer.

An Ins(1,4,5)P3 receptor in Paramecium is associated with the osmoregulatory system

In the ciliate Paramecium, a variety of well characterized processes are regulated by Ca2+, e.g. exocytosis, endocytosis and ciliary beat. Therefore, among protozoa, Paramecium is considered a model organism for Ca2+ signaling, although the molecular identity of the channels responsible for the Ca2+ signals remains largely unknown. We have cloned - for the first time in a protozoan - the full sequence of the gene encoding a putative inositol (1,4,5)-trisphosphate (Ins(1,4,5)P3) receptor from Paramecium tetraurelia cells showing molecular characteristics of higher eukaryotic cells. The homologously expressed Ins(1,4,5)P3-binding domain binds [3H]Ins(1,4,5)P3, whereas antibodies unexpectedly localize this protein to the osmoregulatory system. The level of Ins(1,4,5)P3-receptor expression was reduced, as shown on a transcriptional level and by immuno-staining, by decreasing the concentration of extracellular Ca2+ (Paramecium cells rapidly adjust their Ca2+ level to that in the outside medium). Fluorochromes reveal spontaneous fluctuations in cytosolic Ca2+ levels along the osmoregulatory system and these signals change upon activation of caged Ins(1,4,5)P3. Considering the ongoing expulsion of substantial amounts of Ca2+ by the osmoregulatory system, we propose here that Ins(1,4,5)P3 receptors serve a new function, i.e. a latent, graded reflux of Ca2+ to fine-tune [Ca2+] homeostasis.

Who speaks up for Inés Fonseca? Representing violence against vulnerable subjects and the ethics of care in fictional narrative about Alzheimer’s disease:Ahora tocad música de baile (2004) by Andrés Barba

This paper studies the Spanish fictional novel by Andrés Barba, Ahora tocad música de baile (2004), one of the first cultural texts dealing entirely with Alzheimer’s disease (AD) to appear in Spain. It argues that the significance of Barba’s fictional novel rests on two important issues: the ethics of representation of violence against vulnerable subjects and the ethics of care. The paper analyses how these two issues allow Barba to create a story in which the verbal and physical abuse to which the person living with Alzheimer’s disease is subjected places the reader, on the one hand, as voyeur/witness of the abuse; and, on the other, as interpreter, and ultimately judge, of the fine line that separates euthanasia, assisted suicide, and murder. The open ending of the novel defers all ethical and moral judgment to the reader. It examines how the novel offers a monolithic perspective about AD, in which care is presented as a burden. In fact, this study shows that the novel’s multi-layered structure and polyphonic nature places the emphasis on stigmas, stereotypes and negative metaphors around AD, as found in contemporary social discourses.

Ein Gang ins Narrenhaus

Aus der Sammlung des Leo Baeck Institute, digitalisiert in Kooperation mit dem Center for Jewish History, NY