Avaliação da proliferação celular, índice apoptótico e da expressão do P53 nos linfomas caninos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Datação Sm-Nd em rocha total e granada do metamorfismo granulítico da região de Tartarugal Grande, Amapá Central

O procedimento experimental do método Sm-Nd utilizado no laboratório de Geologia Isotópica Pará-Iso (Universidade Federal do Pará) é apresentado detalhadamente para poder ser utilizado como referência pelos usuários do laboratório. A datação Sm-Nd de granulitos félsicos da área de Tartarugal Grande, nordeste do Bloco Arqueano Amapá, (sudeste do Escudo das Guianas) forneceu idades isocrônicas rocha total-granada de 2017 ± 12 Ma, 1981,6 ± 2,8 Ma e 2018 ± 2,3 Ma. A análise das mesmas amostras no Laboratório de Geocronologia (Universidade de Brasília) indicou idades de 2037 ± 8,4 Ma, 1988 ± 11 Ma e 2013 ± 15 Ma, respectivamente. Esses resultados indicam que temperaturas acima de 700°C foram alcançadas pelos granulitos de Tartarugal Grande entre 2,04 - 1,98 Ga, comprovando uma idade tardi-Transamazônica para o evento de alto grau metamórfico, na região nordeste do Bloco Arqueano Amapá. As idades-modelo T_DM(Nd) entre 3,15 Ga e 2,79 Ga constituem mais um registro do evento principal de acresção crustal mesoarqueano, já identificado na porção sudeste do Escudo das Guianas.

Atividade pozolânica dos resíduos cauliníticos das indústrias de mineração de caulim da Amazônia

As regiões do Rio Capim e do Rio Jari são os principais distritos caulinitícos da Região Amazônica, detentores das maiores reservas brasileiras de caulim de alta alvura para aplicações como cobertura de papel. No processamento do caulim são gerados vários tipos de resíduos processados e não processados. O objetivo deste trabalho foi investigar a reatividade das pozolanas produzidas a partir da calcinação e moagem destes resíduos, avaliando a influência da mineralogia de cada tipo de caulinita (com maior ou menor quantidade de defeitos na estrutura cristalina) sobre a temperatura de queima e, consequentemente, nas características do produto final, de modo a obter o material de maior reatividade com um menor dispêndio de energia. Os resultados mostraram que as pozolanas produzidas a partir dos resíduos apresentaram alta reatividade, sendo inclusive superiores as das obtidas com as pozolanas disponíveis comercialmente. As pozolanas produzidas das caulinitas com maior grau de defeitos na estrutura cristalina demandaram temperaturas mais reduzidas que a com menor grau de defeitos. O emprego de caulinitas com maior quantidade de defeitos na estrutura cristalina reduz os custos de produção das pozolanas, sem que haja perda de qualidade ou de reatividade do produto.

Immunodetection of cells with a CD44+/CD24-phenotype in canine mammary neoplasms

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Finasteride Inhibits Human Prostate Cancer Cell Invasion through MMP2 and MMP9 Downregulation

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Modulation of HJURP (Holliday Junction-Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Geological and geophysical data integration for delimitation of mineralized areas in a supergene manganese deposits

Geophysical methods are widely used in mineral exploration. This paper discusses the results of geological and geophysical studies in supergene manganese deposits of southern Brazil. Mineralized zones as described in geological surveys were characterized as of low resistivity (20 Omega.m) and high chargeability (30ms), pattern found also in oxides and sulfite mineral deposits. Pseudo-3D modeling of geophysical data allowed mapping at several depths. A relationship between high chargeability and low resistivity may define a pattern for high grade gonditic manganese ore. Large areas of high chargeability and high resistivity may result in accumulation of manganese and iron hydroxides, due to weathering of the gonditic ore, dissolution, percolation and precipitation.

Avaliação de biomarcadores moleculares em mulheres com câncer de ovário

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Análise histopatológica de biópsia prostática guiada pelo ultrassom transretal com 10 e 12 fragmentos: ensaio clínico prospectivo controlado

Pós-graduação em Bases Gerais da Cirurgia - FMB

Gene expression profiling in leiomyosarcomas and undifferentiated pleomorphic sarcomas: SRC as a new diagnostic marker

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Caracterização geológica e estrutural da porção centro-norte do greenstone belt de Faina, Faina-GO

The area where the study was conducted is located in the central-western state of Goias. It geologically inserts the northern portion of the Greenstone Belt of Faina which belongs to the Archean terranes that fits in Brasília Fold Belt and Tocantins Structural Province. This region is known for its greenstone lode gold potential and it was heavily exploited by pioneers and prospectors, leaving many records for where they have been through. Preliminary work done by Orinoco Brasil Mineração in their required areas at the region showed that the environment is promising for gold mineralization and that the ore is controlled by structures. Therefore the objectives of this work were the geological and structural mapping in semi detail scale to improve geological, stratigraphic and structural controls present attributing possible ore understanding. With the development of the work there were recognized on the desktop three structural domains separated by a thrust fault. For each domain were discriminated the geological units ranging in gneisses, quartzites formed from coarse sediments arcoseanos, and schists. By mapping structures there were found five deformation phases, Dn-2, Dn-1, the Dn event that generated the main foliation (Sn) in high representation and two post-stages Dn with brittle late manifestations. The detail mapping of the Rattlesnake Gallery showed that the mineralized quartz vein is consistent with axial-plane foliation Sn-2 belonging to the oldest deformation Dn-2 phase and that the high grade is distributed in the hinge region folds of the same phase

Análises histopatológicas, bioquímicas e moleculares sobre os efeitos da interação entre o uso de altas doses de decanoato de nadrolona e o exercício resistido durante a fase pós-púbere sobre a próstata de ratos em processo de envelhecimento

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação da quimioterapia metronômica em carcinomas mamários de cadelas por imunomarcações

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Results of screening for cervical cancer among pregnant and non-pregnant women in Brazil

Objective: To compare cervical cytology test results among pregnant and non-pregnant women, and to assess associations with age, screening history, and onset of sexual intercourse. Methods: A retrospective analysis was conducted of cervical smears obtained from women aged 18-34 years in the Campinas region of Brazil between January 2000 and December 2009. Eligible participants had not undergone cytological screening within the previous year and had no history of precursor lesions or cervical cancer. Multinomial logistic regression was performed for different age groups, with high-grade squamous intraepithelial lesions (HSILs) as the endpoint. Results: Overall, 3072 (0.4%) of 861 353 non-pregnant women and 135 (0.4%) of 37 568 pregnant women had HSILs. Odds of HSIL among pregnant and non-pregnant women did not differ in any age group. An increased age at first sexual intercourse among pregnant women reduced odds of HSILs in all age groups (odds ratio 0.9 [95% confidence interval 0.8-0.9] for all). Among women aged 21-24 years, 25-29 years, and 30-34 years, some associations were identified between an interval of less than 5 years since previous screening and reduced odds of HSILs. Conclusion: Mandatory cervical cytology screening does not seem to be necessary for pregnant women; protocols in place for non-pregnant women should be followed. (C) 2015 Published by Elsevier Ireland Ltd. on behalf of International Federation of Gynecology and Obstetrics.

Ultramafic complexes and associated mineral deposits in the Precambrian of eastern Minas Gerais, Brazil

Based on field work, prospection and petrographic studies ultramafic complexes and their mineral deposits from eastern Minas Gerais in southeastern Brazil are generally outlined to form a basis for future investigations in this region. The bodies dealt with occur at Ipanema, Córrego Novo, Bela Vista de Minas, Rio Pomba and Liberdade. These ultramafic bodies are generally enclosed in high-grade gneisses and consist of serpentinized peridotites and harzburgites which were metamorphosed together with their country rocks in upper amphibolite to granulite facies. Weathering of these rocks gives rise to nickeliferous laterite, while metamorphism has resulted in anthophyllite asbestos and talc deposits. © 1985 Springer-Verlag.