A influência do genótipo da ECA sobre a aptidão cardiovascular de jovens do sexo masculino moderadamente ativos

FUNDAMENTO: O gene da enzima conversora de angiotensina (gene ECA) tem sido amplamente estudado em relação a fenótipos de aptidão cardiorrespiratória, contudo a associação do genótipo da ECA com corridas de meia-distância tem sido pouco investigada. OBJETIVO: O presente estudo investigou a possível influência da enzima conversora de angiotensina (ECA) (I/D) sobre a aptidão cardiovascular e o desempenho em corridas de meia-distância por parte de brasileiros jovens do sexo masculino. A validade da previsão de VO2max em relação ao genótipo da ECA também foi analisada. MÉTODOS: Um grupo homogêneo de homens jovens moderadamente ativos foi avaliado em um teste de corrida (V1600 m; m.min-1) e em um teste adicional em esteira ergométrica para a determinação de VO2max. Posteriormente, o [(0,177*V1600m) + 8.101] VO2max real e previsto foi comparado com os genótipos da ECA. RESULTADOS: O VO2max e V1600m registrados para os genótipos DD, ID e II foram 45,6 (1,8); 51,9 (0,8) e 54,4 (1,0) mL.kg-1.min-1 e 211,2 (8,3); 249,1 (4,3) e 258,6 (5,4 ) m.min-1, respectivamente e foram significativamente mais baixos para os genótipos DD (p < 0,05). O VO2max real e previsto não diferiram entre si, apesar do genótipo da ECA, mas o nível de concordância entre os métodos de VO2max real e estimado foi menor para o genótipo DD. CONCLUSÃO: Concluiu-se que existe uma possível associação entre o genótipo da ECA, a aptidão cardiovascular e o desempenho em corridas de média distância de jovens do sexo masculino moderadamente ativos e que a precisão da previsão do VO2max também pode ser dependente do genótipo da ECA dos participantes.

Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension

Abstract Background: Resistance training (RT) has been recommended as a non-pharmacological treatment for moderate hypertension. In spite of the important role of exercise intensity on training prescription, there is still no data regarding the effects of RT intensity on severe hypertension (SH). Objective: This study examined the effects of two RT protocols (vertical ladder climbing), performed at different overloads of maximal weight carried (MWC), on blood pressure (BP) and muscle strength of spontaneously hypertensive rats (SHR) with SH. Methods: Fifteen male SHR ENT#091;206 ± 10 mmHg of systolic BP (SBP)ENT#093; and five Wistar Kyoto rats (WKY; 119 ± 10 mmHg of SBP) were divided into 4 groups: sedentary (SED-WKY) and SHR (SED-SHR); RT1-SHR training relative to body weight (~40% of MWC); and RT2-SHR training relative to MWC test (~70% of MWC). Systolic BP and heart rate (HR) were measured weekly using the tail-cuff method. The progression of muscle strength was determined once every fifteen days. The RT consisted of 3 weekly sessions on non-consecutive days for 12-weeks. Results: Both RT protocols prevented the increase in SBP (delta - 5 and -7 mmHg, respectively; p > 0.05), whereas SBP of the SED-SHR group increased by 19 mmHg (p < 0.05). There was a decrease in HR only for the RT1 group (p < 0.05). There was a higher increase in strength in the RT2 (140%; p < 0.05) group as compared with RT1 (11%; p > 0.05). Conclusions: Our data indicated that both RT protocols were effective in preventing chronic elevation of SBP in SH. Additionally, a higher RT overload induced a greater increase in muscle strength.

Aufbau eines Hochspannungs-Isolations-Prüfplatzes

In der Arbeit wird ein Hochspannungs-Isolations-Prüfplatz entwickelt. Dieser dient zum Testen von Isolationsstrukturen in speziellen Proben bei der Berliner Glas KGaA Herbert Kubatz GmbH & Co. Der Prüfplatz muss programmierbar sein, vorhandenes Equipment soll nach Möglichkeit genutzt werden. Um eine geeignete Lösung zu finden, werden in Vorversuchen die möglichen Parameter ermittelt und gegebenenfalls eingeschränkt. Die Betrachtung der Themenschwerpunkte Digitalisierung, Strommessung, Spannungsmessung, Steuerung der Prüfspannung sowie Software führen zu Auswahl und Aufbau/Programmierung der einzelnen Komponenten. Des Weiteren wird die Sicherheit beim Umgang mit dem Prüfaufbau, besonders hinsichtlich der verwendeten Hochspannung, erörtert. Als Ergebnis wird der Prüfplatz mit einem Hochspannungsnetzteil aufgebaut, welches über eine USB-Datenbox mit der Software auf einem PC gesteuert wird. Die Ausgabe von Strom und Spannung des Netzteils wird aufgezeichnet. Ein USB-Oszilloskop zeichnet mittels eines Hochspannungstastkopfs die Spannung und mittels einer Stromzange den Strom auf. Mit dieser Strommessung wird ein elektrischer Durchschlag detektiert und an die Software gemeldet. Die Eignung des gewählten Equipments wird nachgewiesen.

Three new birds of the genus stachyris, by H. G. Deignan.

v.24:no.10(1939)

The high priest's grave, Chichen Itza, Yucatan, Mexico; a manuscript / by Edward H. Thompson. Prepared for publication, with notes and introduction by J. Eric Thompson --

v.27:no.1(1938)

A cooperative appproach to queue allocation of indivisible objects

We consider the allocation of a finite number of indivisible objects to the same number of agents according to an exogenously given queue. We assume that the agents collaborate in order to achieve an efficient outcome for society. We allow for side-payments and provide a method for obtaining stable outcomes.

On games corresponding to sequencing situations with precedence relations

In this paper we study a class of cooperative sequencing games that arise from one-machine sequencing situations in which chain precedence relations are imposed on the jobs. It is shown that these sequencing games are convex.

OpenURL i l'enllaçat SFX

No fa gaires anys de les primeres recerques acadèmiques liderades per Herbert Van de Sompel a la Universitat de Gant a Bèlgica, les quals van donar com a resultat la formulació de l'estàndard OpenURL i el desenvolupament del servidor d'enllaços per a les biblioteques SFX, posant el control dels enllaços en mans del bibliotecari. Aquest article considera breument les primeres iniciatives sobre els enllaços, explica el propòsit i l'estructura d'OpenURL i el paper dels components: les fonts, els objectius i el servidor d'enllaços, centrant-se en el servidor d'enllaços SFX.

Statistique des coûts et des prestations

On connaît le manque de données permettant de s'assurer que les prestations prises en charge par la LAMal sont adéquates, efficaces et économiques. L'Office fédéral de la santé publique (OFSP) a décidé de proposer et faire valider quelques nouveaux indicateurs. Le but du présent article est de présenter les projets qui vont être mis en oeuvre entre l'été 2008 et 2011. [Intertitres] Identification des maladies. Episodes ambulatoires. Mesure de l'impact des soins sur l'état de santé. Prévention. Etablissement de profils de pratique médicaux. Hospitalisations potentiellement évitables. Calendrier et coût des projets.