Gross total resection rates in contemporary glioblastoma surgery: results of an institutional protocol combining 5-aminolevulinic acid intraoperative fluorescence imaging and brain mapping

Complete resection of contrast-enhancing tumor has been recognized as an important prognostic factor in patients with glioblastoma and is a primary goal of surgery. Various intraoperative technologies have recently been introduced to improve glioma surgery.

Etwas gross aufschreiben. Quellenkritische Anmerkungen zum "Zeytregister" des Ulmer Chronisten Hans Heberle (1597-1677)

Das "Zeytregister" des Ulmer Bauern und Landhandwerkers Hans Heberle ist in seiner Art eine einzigartige Hinterlassenschaft eines bäuerlichern Schriftstellers des 17. Jahrhunderts. Der Gesichtskreis Heberles geht weit über den engen Horizont der Wirtschaftsführung hinaus, indem er persönliche Erfahrungen mit der Schilderung der Kriegsereignisse seiner Zeit verbindet. Unter Berücksichtigung von Schreibintention und -praxis relativieren sich indes die Möglichkeiten einer persönlichkeitsnahen Ausschöpfung der Quelle im Sinne eines 'Ego-Dokuments'. So sind den im wesentlichen auf Geburt und Tod beschränkten Notaten über die eigene Familie, über persönliche Erlebnisse und Beobachtungen aus näherer Anschauung durch die absorbierende Kriegsschilderung Grenzen auferlegt. Die selektive Auswahl der Themenpunkte und das weitestgehende Zurücktreten affektiver Momente erklärt sich auch durch die technische Verfahrensweise Heberles, der nach Ausweis inhaltlicher und formaler Aspekte der Handschrift in deutlichem zeitlichem Ereignisabstand an seiner Chronik arbeitete.

Revenue Management in Make-To-Order Manufacturing: Case Study of Capacity Control at ThyssenKrupp VDM

While revenue management (RM) is traditionally considered a tool of service operations, RM shows considerable potential for application in manufacturing operations. The typical challenges in make-to-order manufacturing are fixed manufacturing capacities and a great variety in offered products, going along with pronounced fluctuations in demand and profitability. Since Harris and Pinder in the mid-90s, numerous papers have furthered the understanding of RM theory in this environment. Nevertheless, results to be expected from applying the developed methods to a practical industry setting have yet to be reported. To this end, this paper investigates a possible application of RM at ThyssenKrupp VDM, leading to considerable improvements in several areas.

Using Dynamic Programming Decomposition for Revenue Management with Opaque Products

Opaque products enable service providers to hide specific characteristics of their service fulfillment from the customer until after purchase. Prominent examples include internet-based service providers selling airline tickets without defining details, such as departure time or operating airline, until the booking has been made. Owing to the resulting flexibility in resource utilization, the traditional revenue management process needs to be modified. In this paper, we extend dynamic programming decomposition techniques widely used for traditional revenue management to develop an intuitive capacity control approach that allows for the incorporation of opaque products. In a simulation study, we show that the developed approach significantly outperforms other well-known capacity control approaches adapted to the opaque product setting. Based on the approach, we also provide computational examples of how the share of opaque products as well as the degree of opacity can influence the results.