989 resultados para atividade proteolítica


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In the relative positioning, even considering that part of the errors due to ionosphere is canceled with the double-difference observations, strong ionospheric effects can occur in maximum solar activity period. However, in minimum solar activity period, the ionospheric effects decrease significantly and therefore an improvement of the relative positioning performance takes place. In this paper we aim at showing that improvement for the scientific and GPS community users. So, have been experiments by using GPS data of two stations of the Brazilian Network for Continuous Monitoring of GPS, forming a baseline of 430 km. The processing were use accomplished with interval of two hours, and only L1 carrier data have been used. The analysis of the obtained results has been carried out from the discrepancies between the "true" coordinates and corresponding ones obtained in the processing. In maximum solar activity period the discrepancy value reached 25 m. on the other hand, in minimum solar activity period, the discrepancy value reached 5,5 m. It is important to emphasize that the majority of the discrepancy values didn't exceed 0,50 m, and in some cases only reached 0,10 m. This shows the increase of application possibilities of the relative positioning using single-frequency GPS receivers in minimum solar activity period.

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One of the main drawbacks of the GPS accuracy for L1 users is the error due to ionosphere. This error depends on the total electron content presents in the ionosphere, as well as of the carrier frequency. Some models have been developed to correct GPS observables of the systematic error due to the ionosphere. The model more known and used is the Klobuchar model, which corrected 50-60% of the ionospheric error approximately. Alternatively, IGS (International GNSS Service) also has developed a model called Global Ionospheric Map (GIM). These maps, in format IONEX, are available in the site of the IGS, and one of the applications of them is to correct the GPS observables of the error due to ionosphere. This work aims at evaluating the quality of GPS point positioning using the IGS ionospheric model in the southerm region of Brazil. Tests carried out had shown an average improvement in the horizontal and vertical determination of 44% and 77%, respectively, when GIM is used in the point positioning.

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The ionosphere is a major source of systematic error in the GPS observables. As this error is directly proportional to the TEC (Total Electron Content), the quality of GPS positioning (especially with single frequency receivers) can be significantly affected by regular changes of TEC. The ionosphere factor is even more relevant in the Brazilian region, where ionospheric phenomena, such as the Equatorial Anomaly, intensify these variations. Taking the above mentioned factors into account, experiments were conducted in this research to evaluate the daily and seasonal behavior of the TEC and the point positioning with GPS (single frequency) in periods of high and low solar activity in the Brazilian region. The results showed a direct correlation between the decrease in electrons density in the ionosphere (period of low solar activity) and improvement in positioning accuracy, as well as a large influence of Equatorial Anomaly on the results of point positioning.

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To analyze influences of the physical activity and sedentary behaviors on indicators of both central and total body fat in male adolescents. Cross-sectional study with 60 male students of age range from 11 to 14 years old. It were evaluated the body mass, height, triceps skinfold, waist circumference, body fat percentage (bioelectrical impedance) and the physical activity level through questionnaire. The physical inactivity prevalence was of 35%, and the excessive total and central body fat were observed in 38.3% and 48.3% of the sample, respectively. There was association of the sedentary behaviors with the excessive total and central body fat (OR = 5.2 e OR = 6.4, respectively), however there was not for physical activity. The adoption of sedentary behaviors is associated at the development of the total and central obesity among male adolescents.

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Objectives: To analyze different physical activities domains in healthy adults and correlate with cardiovascular risk factors. Methods: The sample was composed by 32 Physical Education undergraduate students, with mean age of 22.6 years old. Adiposity was assessed by waist circumference (WC), body mass index (BMI) and bioelectrical impedance. Additionally, fast glucose (10-12 hours), systolic (SBP) and diastolic (DBP) blood pressure were assessed. Physical activity level was assessed by questionnaire (Baecke et al., 1982). Results: sports activities and leisure time were not related with cardiovascular risk factors. However, job activities were negatively related with %BF, SBP and DBP. Conclusion: Different physical activity domains should be considered when analyzing its associations with health indicators.

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This research deals with the activity of text revision. It aims at understanding the work of the text reviewer, taking into consideration the professional experiences of the subjects who work in the area. It s theoretical basis comes from Bakhtin Circle, mainly the concept of verbal interaction formulated from reflections on language used in different spheres of human activities, which implies the notions of discourse genres, alterity, as well as exotopy. The methodology follows the tradition of the qualitative and interpretative research. The data is composed of the statements of text reviewers both in handbooks and interviews, as well as of the description of the researcher s own experience as text reviewer. The results indicate that the revision activity needs to be orientated by a dialogical conception of language, which takes into consideration the interaction between the reviewer and the author, aiming the text finalization

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This work aims at analyzing the activities presented in the book On Stage for junior high school students, which was selected by IFRN, as well as checking out the students interest for play activities. We have come from the point that playing activities can contribute to the increasing of motivation for the teaching of English (BROUGERE, 1999; WRIGHT, BETTERIDGE, BUCKBY, 2006; LANGRAN e PURCELL, 1994). At first place, our research is a document analysis and in second place, it is an action research. We have proposed two questionnaires for the participants of this work, all of them are High school students at IFRN-Campus Zona Norte, in order to check out their interests and the degree of motivation for the English learning before and after the carrying out of play activities. The obtained data also showed that the students became more motivated and interested in the classes after working with play activities, and most of the students agreed with the inclusion of these activities in the selected course book. The result of our work proved the benefits of play activities according to researches available in the literature about this subject. From the results acquired in the present work, we suggest that play activities should be included in English course books, even when they are addressed to High School teaching in order to help increasing the motivation for the learning of a foreign language

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Objectives: To study the relationship between the level of physical activity in daily life and disease severity assessed by the BODE index in patients with chronic obstructive pulmonary disease (COPD). Methods: Sixty-seven patients with COPD (36 men) with forced expiratory volume in the first second (FEV(1)) of 39 (27-47)% predicted and age of 66 (61-72) years old were evaluated by spirometry, dyspnea levels (measured by the Medical Research Council scale, MRC) and by the 6-minute walking test (6MWT). The BODE index was calculated based on the body mass index (weight/height(2)), FEV(1), MRC and 6MWT, and then the patients were divided in four quartiles according to their scores (Quartile I: 0 to 2 points, n=15; Quartile II: 3 to 4 points, n=20; Quartile III: 5 to 6 points, n=23; Quartile IV: 7 to 10 points, n=9). Two activity monitors (DynaPort (R) and SenseWear (R)) were used to evaluate the level of physical activity in daily life. The Kruskal-Wallis test (Dunns's post-hoc test), the Mann-Whitney test and the Spearman Correlation Coefficient were used for statistical analysis. Results: There were modest correlation between the BODE index and the time spent walking per day, the total daily energy expenditure and the time spent in moderate and vigorous activities per day (-0.32 <= r <=- 0.47; p <= 0.01 for all variables). When comparing the pooled quartiles I+II with III+IV, there were significant difference between the time spent walking per day, the total daily energy expenditure and the time spent in moderate activities per day (p <= 0.05). Conclusion: The level of physical activity in daily life has a modest correlation with the classification of COPD severity assessed by the BODE index, reflecting only differences between patients with classified as mild-moderate and severe-very severe COPD.

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A utilização de extratos vegetais vem se tornando uma alternativa importante para a prevenção de doenças periodontais. Este trabalho objetivou desenvolver uma formulação de enxagüatório bucal, contendo, em associação, extratos hidroalcoólicos de Rosmarinus officinalis, Plantago major, Tabebuia impetiginosa, Achillea millefollium e Nasturtium officinale; avaliar sua composição farmacognóstica e sua atividade antibacteriana, como também da fórmula proposta. Foram realizados estudos de pré-formulação e análises farmacognósticas para as espécies vegetais. A atividade antibacteriana in vitro foi observada por meio dos métodos de difusão em disco de papel, por hole- plate e por template, frente a Staphylococcus aureus, Bacillus subtilis, Escherichia colik, Enterococcus faecalis e Pseudomonas aeruginosa. A concentração inibitória mínima (CIM) foi determinada por meio do método de macrodiluições sucessivas em caldo. Os resultados obtidos apresentaram-se de acordo com o histórico farmacognóstico das drogas estudadas. Todas as bactérias foram inibidas pelos extratos, observando-se que as espécies S. aureus e B. subtilis mostraram, aparentemente, maior sensibilidade. A CIM variou, em relação a sensibilidade de cada espécie bacteriana estudada, de 312,5 µL/mL a 1250 µL/mL para os extratos vegetais e de 625 µL/mL a 2500 µL/mL para o enxaguatório bucal. São necessários estudos complementares para a confirmação da eficácia deste produto e sua utilização na prevenção de doenças periodontais.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Avaliou-se a atividade antiinflamatória do extrato etanólico de própolis - EEP, . sobre o edema desencadeado por carragenina, dextrana e histamina. O EEP apresentou dose eficaz (DE50) de 650 mg/kg (v.o), inibindo significativamente o processo inflamatório desencadeado pela carragenina, mas não inibiu o produzido por dextrana. O EEP antagonizou ainda o efeito edematogênico produzido por histamina. Nas úlceras produzidas por estresse, o EPP inibiu de forma significativa a geração dos diversos tipos classificados. em todos os parâmetros analisados no estudo da toxicidade em fase de tratamento subcrônico , (hematológicos, bioquímicos e histopatológicos), o grupo tratado com o EEP não apresentou diferença significativa em relação ao grupo controle. Desta forma, sugere-se que na dose de 650 mg/kg (dose eficaz) não existe a presença de efeitos tóxicos que possam comprometer a utilização deste extrato.

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As radiações ultravioleta (divididas em ultravioleta A, B e C), por possuírem diferentes energias e comprimentos de onda, apresentam diferentes atividades sobre os organismos, sendo que algumas destas atividades são benéficas e outras, não. A fim de evitar os malefícios causados por estas radiações, existem produtos denominados fotoprotetores. Uma vez que os flavonóides são considerados um fator importante de proteção contra a radiação ultravioleta, alguns estudos concentram-se na avaliação da atividade fotoprotetora que algumas plantas, compostas por flavonóides, possam apresentar. Sendo assim, este trabalho teve como objetivo avaliar a atividade fotoprotetora de extratos das flores e folhas de Achillea millefolium L. através de testes in vitro por espectrofotometria no ultravioleta. Embora a literatura descreva a presença de flavonóides nas flores e folhas de A. millefolium, não foi encontrada atividade fotoprotetora nos extratos testados.

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Os objetivos do presente trabalho foram avaliar os efeitos de extratos de Momordica charantia sobre o crescimento micelial e a germinação de conídios de Colletotrichum musae, e a eficiência destes extratos no controle da antracnose, causada por C. musae, em bananas. Extratos aquoso e hidroetanólico, obtidos de folhas e ramos, na concentração de 50% em relação ao volume adicionado, em meio sólido, proporcionaram 71 e 65% de inibição do crescimento micelial, respectivamente, enquanto que em meio líquido, a inibição do crescimento micelial foi de 86 e 81%, respectivamente. Somente o extrato aquoso e o tiofanato metílico, nas concentrações de 50% e 1000 µg mL-1 respectivamente, proporcionaram 100% de inibição da germinação de esporos de C. musae. Os extratos metanólico e aquoso inibiram em 80 e 70%, respectivamente, o desenvolvimento das lesões em bananas, quando aplicados até dois dias antes da inoculação do fungo. Estes resultados foram semelhantes ao tratamento com tiofanato metílico, que inibiu 80% do desenvolvimento das lesões. Confirma-se a presença de substância antifúngica nos extratos de M. charantia e outros estudos devem ser realizados para viabilizar seu uso no controle da antracnose da banana.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)