Successful prevention of transmission of integrase resistance in the Swiss HIV Cohort Study.

Prevalence of integrase inhibitor (INSTI) transmitted drug resistance (TDR) may increase with the increasing use of INSTIs. We analysed the prevalence of INSTI TDR in the Swiss HIV Cohort Study (2008-2014). In 1 of 1,316 (0.1%) drug-naïve samples a major INSTI TDR mutation was detected. Prevalence was stable although INSTIs were increasingly used. We showed that this is in contrast to the introduction of previous drug classes where more treatment failures with resistant strains occurred and TDR was observed more rapidly. We demonstrated on a population-level that it is possible to avoid TDR affecting a new drug class for years.

Prevention of cement leakage into the hip joint by a standard cement plug during PFN-A cement augmentation: a technical note.

Medial penetration of the helical blade into the hip joint after fixation of trochanteric fractures using the proximal femur nail antirotation (PFN-A) is a potential failure mode. In low demand patients a blade exchange with cement augmentation may be an option if conversion to total hip arthroplasty is unfeasible to salvage the cut-through. This article describes a technique to avoid intraarticular cement leakage using a cement plug to close the defect in the femoral head caused by the cut-through.

Group-Based Symptom Trajectories in Indicated Prevention of Adolescent Depression

Background: Adolescent depression prevention research has focused on mean intervention outcomes, but has not considered heterogeneity in symptom course. Here, we empirically identify subgroups with distinct trajectories of depressive symptom change among adolescents enrolled in two indicated depression preven- tion trials and examine how cognitive-behavioral (CB) interventions and baseline predictors relate to trajectory membership. Methods: Six hundred thirty-one participants were assigned to one of three conditions: CB group intervention, CB bibliotherapy, and brochure control. We used group-based trajectory modeling to identify trajectories of depressive symptoms from pretest to 2-year follow-up. We examined associations between class membership and conditions using chi- square tests and baseline predictors using multinomial regressions. Results: We identified four trajectories in the full sample. Qualitatively similar trajectories were found in each condition separately. Two trajectories of positive symptom course (low-declining, high-declining) had declining symptoms and were dis- tinguished by baseline symptom severity. Two trajectories of negative course (high-persistent, resurging), respectively, showed no decline in symptoms or de- cline followed by symptom reappearance. Participants in the brochure control condition were significantly more likely to populate the high-persistent trajectory relative to either CB condition and were significantly less likely to populate the low-declining trajectory relative to CB group. Several baseline factors predicted trajectory classes, but gender was the most informative prognostic factor, with males having increased odds of membership in a high-persistent trajectory rel- ative to other trajectories. Conclusions: Findings suggest that CB preventive interventions do not alter the nature of trajectories, but reduce the risk that adolescents follow a trajectory of chronically elevated symptoms.

Prevention of hemolytic disease of the fetus and newborn due to rh isoimmunization /

Mode of access: Internet.

Impact of air pollution on the consumption of medical services : cost of hospitalization in the Portland metropolitan area /

Mode of access: Internet.

Guidelines for prevention of transmission of human immunodeficiency virus and hepatitis B virus to health-care and public-safety workers : a response to P.L. 100-607, The Health Omnibus Programs Extension Act of 1988.

Item 499-F-3.

How paupers are made; an address on the prevention of pauperism ...

Mode of access: Internet.

Prevention of consumption ...

Reprint fr. Annual report of the Mich. State Board of Health, 1893.

Social defence : (Prevention of crime and treatment of offenders, suppression of traffic in persons and of exploitation of the prostitution of others).

v. 2. 1952.IV.16 and 1953.IV.16 -- v. 3. 1954.IV.6 and 1954.IV.18.

The prevention of cobalticyanide poisoning of ion exchange resins used on South African gold ore residue leach liquors /

"Date Declassified: September 23, 1955."

Report from the Standing Committee ... on the prevention of corruption bill (H.L.) with the proceedings of the Committee.

Mode of access: Internet.

The prevention of silting and erosion in watercourses /

Mode of access: Internet.