Lésions cérébrales du prématuré et techniques d'imagerie à visée pronostique du développement neurocognitif [Cerebral brain injury in preterm infants and the role of neuroimaging in predicting neurodevelopmental outcomes].

Due to advances in neonatal intensive care over the last decades, the pattern of brain injury seen in very preterm infants has evolved in more subtle lesions that are still essential to diagnose in regard to neurodevelopmental outcome. While cranial ultrasound is still used at the bedside, magnetic resonance imaging (MRI) is becoming increasingly used in this population for the assessment of brain maturation and white and grey matter lesions. Therefore, MRI provides a better prognostic value for the neurodevelopmental outcome of these preterms. Furthermore, the development of new MRI techniques, such as diffusion tensor imaging, resting state functional connectivity and magnetic resonance spectroscopy, may further increase the prognostic value, helping to counsel parents and allocate early intervention services.

Oeuvres de La Rochefoucauld. [Mémoires]. Tome 1 / nouv. éd. revue sur les plus anciennes impressions et augm. de morceaux inédits, de variantes, de notices, de notes, de tables particulières pour les "Maximes" et pour les "Mémoires", d'un lexique des mots et locutions remarquables, d'un portr., de fac-sim., etc. par MM. D. L. Gilbert et J. Gourdault

Collection : Les grands écrivains de la France

Oeuvres de La Rochefoucauld. [Mémoires]. Tome 3 / Partie 1 / nouv. éd. revue sur les plus anciennes impressions et augm. de morceaux inédits, de variantes, de notices, de notes, de tables particulières pour les "Maximes" et pour les "Mémoires", d'un lexique des mots et locutions remarquables, d'un portr., de fac-sim., etc. par MM. D. L. Gilbert et J. Gourdault

Collection : Les grands écrivains de la France

Oeuvres de La Rochefoucauld. [Mémoires]. Tome 3 / Partie 2 / nouv. éd. revue sur les plus anciennes impressions et augm. de morceaux inédits, de variantes, de notices, de notes, de tables particulières pour les "Maximes" et pour les "Mémoires", d'un lexique des mots et locutions remarquables, d'un portr., de fac-sim., etc. par MM. D. L. Gilbert et J. Gourdault

Collection : Les grands écrivains de la France

Oeuvres de La Rochefoucauld. [Mémoires]. Tome 2 / nouv. éd. revue sur les plus anciennes impressions et augm. de morceaux inédits, de variantes, de notices, de notes, de tables particulières pour les "Maximes" et pour les "Mémoires", d'un lexique des mots et locutions remarquables, d'un portr., de fac-sim., etc. par MM. D. L. Gilbert et J. Gourdault

Collection : Les grands écrivains de la France

La protecció de la part feble del contracte en el dret civil català i en el dret civil europeu

La investigación analiza si, con el horizonte del Libro Sexto del Código Civil de Cataluña relativo a las obligaciones y los contratos, el legislador catalán tiene que mantener el modelo tradicional de la rescisión por lesión ultradimidium, o bien tiene que integrar esta institución en el marco de la protección de la parte débil del contrato, en la línea de las modernas propuestas de derecho europeo.

Safety and immunomodulatory effects of three probiotic strains isolated from the feces of breast-fed infants in healthy adults: SETOPROB study.

We previously described the isolation and characterization of three probiotic strains from the feces of exclusively breast-fed newborn infants: Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036. These strains were shown to adhere to intestinal mucus in vitro, to be sensitive to antibiotics and to resist biliary salts and low pH. In the present study, a multicenter, randomized, double-blind, placebo-controlled trial with 100 healthy volunteers in three Spanish cities was carried out to evaluate the tolerance, safety, gut colonization and immunomodulatory effects of these three probiotics. Volunteers underwent a 15-day washout period, after which they were randomly divided into 5 groups that received daily a placebo, a capsule containing one of the 3 strains or a capsule containing a mixture of two strains for 30 days. The intervention was followed by another 15-day washout period. Patients did not consume fermented milk for the entire duration of the study. Gastrointestinal symptoms, defecation frequency and stool consistency were not altered by probiotic intake. No relevant changes in blood and serum, as well as no adverse events occurred during or after treatment. Probiotic administration slightly modified bacterial populations in the volunteers' feces. Intestinal persistence occurred in volunteers who received L. rhamnosus CNCM I-4036. Administration of B. breve CNCM I-4035 resulted in a significant increase in fecal secretory IgA content. IL-4 and IL-10 increased, whereas IL-12 decreased in the serum of volunteers treated with any of the three strains. These results demonstrate that the consumption of these three bacterial strains was safe and exerted varying degrees of immunomodulatory effects.

Oeuvres complètes de Montesquieu / avec des notes de Dupin, Crevier, Voltaire, Mably, Servan, La Harpe, etc. ... [et une Notice sur la vie de Montesquieu, par C.-A. Walckenaër ; publié par L. Parelle]

Comprend : Notice sur la vie de Montesquieu...

Response des curez de Paris, pour soustenir le factum par eux présenté à Messieurs les vicaires généraux, pour demander la censure de l'Apologie des casuistes . Contre un escrit intitulé "Réfutation des calomnies nouvellement publiées par les autheurs d'un factum sous le nom de Messieurs les curez de Paris, etc. ..."

[Factum (Paris. Curés). 1658]

Les Biblioteques públiques per a infants a Catalunya: anàlisi i propostes de millora de la praxis educativa

Les biblioteques públiques per a infants a Catalunya: Anàlisi i propostes de millora de la praxis educativa és una recerca que pretén donar a conèixer la realitat actual catalana entorn les biblioteques públiques infantils, tot fent incidència en les potencialitats educatives que presenten les biblioteques infantils i juvenils. En el desenvolupament del treball s’han recollit i analitzat els avantatges i els inconvenients dels diferents models de biblioteca estudiats, i les possibles relacions que s’estableixen entre aquests models i alguns aspectes com l’autonomia dels infants, els tipus de projectes i activitats infantils que desenvolupen o les repercussions dels espais

New clinical practice guideline on enteral feeding in very low birth wieght infants; second part

INTRODUCTION: The nutrition of very low birth weight (VLBW) infants is aimed at promoting a similar growth to that occurring in the uterus. However, in practice this is difficult to achieve and extrauterine growth restriction is frequent. The current tendency is to avoid this restriction by means of early parenteral and enteral nutrition. Nonetheless, uncertainty about many of the practices related with nutrition has resulted in a great variation in the way it is undertaken. In 2009 and 2011 in our hospital there was an unexpected increase in necrotizing enterocolitis. To check to see wether our nutrition policy was involved, we underlook a systematic review and drewup clinical practice guidelines (CPG) about enteral feeding in VLBW infants. New considerations about the duration of the fortification and the use of probiotics have led to an update of these CPG. METHODS: A total of 21 clinical questions were designed dealing with the type of milk, starting age, mode of administration, rate and volume of the increments, fortification, use of probiotics and protocol. Afete conducting a systematic search of the available evidence, the information was contrasted and summarized in order to draw up the recommendations. The quality of the evidence and the strength of the recommendations were determined from the SIGN scale. COMMENT: These CPG aim to help physicians in their decision making. The protocolized application of wellproven measurements reduces the variation in clinical practice and improves results.