Avaliação das áreas de conflito de uso em APP na microbacia Ribeirão do Veado, Piratininga (SP) por meio de geotecnologias

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Identification and enzymatic characterization of acid phosphatase from Burkholderia gladioli

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Formação inicial de professores de ciências: reflexões a partir das abordagens das estratégias de ensino e aprendizagem em um curso de licenciatura

We developed a case study aimed to identify and to analyze how the approach to teaching and learning strategies occurs in a science teaching degree course and what are the possible influences of this formation on the pedagogical practice of these educators. The analysis focused on documents, questionnaires and interviews with lecturers and students. There is reduced diversity of strategies in the disciplines of the specific area, with prevalence of expository classes and of laboratory, and the lecturers seem to believe that a good knowledge of specific content is enough for teaching. Despite that pedagogical disciplines do explore diverse practices, many students incorporate the academic view prevailing in the course, repeating the model of their lecturers. We stress the need for initial teacher training to take into account both aspects, the domain of the specific contents and the best ways to mediate them, forming intellectuals able to discuss and to redraw their educative actions in a perspective of transformation of the reality.

Educação ambiental nos anos finais do ensino fundamental em uma escola do campo: uma análise a partir do projeto político pedagógico

Environmental education (EE), a critical component to face the environmental crisis, must be present in formal education in a continuous, permanent and transversal way. Studies show, however, that EE occurs, often, in a sporadic and discontinuous way, and that it is mainly linked to Sciences. The objective of this study was to investigate the inclusion of environmental subjects in the Political Pedagogical Project (PPP) of a rural school, in Araraquara, SP. Through documentary analysis of the PPP, proposals for the Environmental Education for the last years of elementary education were examined. The results allowed the understanding, in a complex and contextualized way, of aspects related to the presence of environmental subjects in the school curriculum. They reveal that the suggestion of working with Environment attend the recommendations of the conference of Tbilisi and of Brazilian National Curriculum (PCN).

Hidrovia e desenvolvimento regional: estudo dos projetos de desenvolvimento dos vales do Tietê e Paraná no Estado de São Paulo

"This paper aims to examine three regional development plans proposed for the region of the valleys of rivers Tietê and Paraná: Rail Project (ISCO, 1994), the Development Plan (CESP, 1996) and Máster Plan (ADTP, 1996). The interest in conducting the study relies on the possibility that it may contribute to the debate on the reshaping of public policy and style necessary to establish a new pattern of regional development in the country"

Os dramas na prosa onírica de Artemidoro

The objective of this paper is to present a Portuguese translation, with notes and commentary, and the corresponding Greek text of a small excerpt of book I (Onir. I. 56.25 -45), of Artemidorus’ Interpretation of dreams, Oneirokritika, based on Pack’s edition (1963), and on Houlihan’s (1997a,b) reviews and of Bowersock (1994)’s. It is a particular and important passage, focused on dreams about tragedy, comedy, choruses and hymns. To this translation, which serves as the basis for the present study of the onirocritic text, other excerpts were added in order to examine the (re)configuration of the dramatic action or hypokrisis into dream interpretations, within the author’s model of analysis, and its relationship with truth and falseness on physis, ethos and tekhne levels; all on a common denominator, memory. A rhetoric basis for author’s onirocritic vision and the keys to onirocritics in the dramatic scenes are discussed.

Preservação do patrimônio escolar no Brasil: notas para um debate

This article comprises of a reflection on the challenges of the school heritage conservation in Brazil. First, it analyses the place for school heritage thin in a much more ample field of cultural heritage. Then, it points out problematic questions assumed in the debate on heritage in the education area and examines the consequent sense of the school converted in “place of memory”. The text defends the indispensability of the insertion of the school heritage in the public, political and specialized debate in the field of conservation as a condition for the development of education heritage in the country.

Transmission network expansion planning considering repowering and reconfiguration

Transmission expansion planning (TEP) is a classic problem in electric power systems. In current optimization models used to approach the TEP problem, new transmission lines and two-winding transformers are commonly used as the only candidate solutions. However, in practice, planners have resorted to non-conventional solutions such as network reconfiguration and/or repowering of existing network assets (lines or transformers). These types of non-conventional solutions are currently not included in the classic mathematical models of the TEP problem. This paper presents the modeling of necessary equations, using linear expressions, in order to include non-conventional candidate solutions in the disjunctive linear model of the TEP problem. The resulting model is a mixed integer linear programming problem, which guarantees convergence to the optimal solution by means of available classical optimization tools. The proposed model is implemented in the AMPL modeling language and is solved using CPLEX optimizer. The Garver test system, IEEE 24-busbar system, and a Colombian system are used to demonstrate that the utilization of non-conventional candidate solutions can reduce investment costs of the TEP problem. (C) 2015 Elsevier Ltd. All rights reserved.

Revisão dos procedimentos operacionais padrão da farmácia-escola Prof. Dr. Antonio Alonso Martinez conforme RDC 67/07

O Projeto de Iniciação Científica foi desenvolvido na Farmácia-Escola Prof. Dr. Antônio Alonso Martinez, uma unidade auxiliar da Faculdade de Ciências Farmacêuticas da UNESP-Araraquara e que é parte integrante do NAC (Núcleo de Atendimento à Comunidade). Por ser vinculada à uma instituição pública ela serve como modelo para toda a comunidade, além de ser um estabelecimento de ensino, pesquisa e extensão. Por isso, ela tem o compromisso de cumprir com todas as exigências legais de maneira exemplar, garantindo a qualidade dos produtos manipulados. Realizou-se a revisão e adequação dos Procedimentos Operacionais Padrão (POPs) presente no Manual de Boas Práticas de Manipulação da Farmácia-Escola, baseando-se nas diretrizes da RDC 67/07 (Anexo I - Boas Práticas de Manipulação em Farmácia) e também uma inspeção na rotina dos processos envolvidos na manipulação e dispensação dos produtos manipulados. Fez-se a aplicação do Roteiro de Inspeção para Farmácia - Anexo VII da RDC 67/07 com a finalidade de constatar e avaliar o cumprimento das Boas Práticas de Manipulação em Farmácias (BPMF). Verificou-se que a Farmácia-Escola ainda não está em conformidade com todos os critérios estabelecidos pela RDC 67/07, mas que mesmo com as dificuldades enfrentadas para se adequar ela atende à quase todos os itens considerados imprescindíveis. Segundo as farmacêuticas responsáveis, medidas corretivas vêm sendo estudadas para que aos poucos todos os itens constantes na Resolução em questão sejam cumpridos.

Desenvolvimento e validação de método bioanalítico aplicado em estudo de farmacocinética pré-clínica e ensaio preliminar de segurança de novo derivado de tiazolidinodiona com atividade antiinflamatória - LYSO-07

Pós-graduação em Ciências Farmacêuticas - FCFAR

Revisão dos procedimentos operacionais padrão da farmácia-escola Prof. Dr. Antonio Alonso Martinez conforme RDC 67/07

O Projeto de Iniciação Científica foi desenvolvido na Farmácia-Escola Prof. Dr. Antônio Alonso Martinez, uma unidade auxiliar da Faculdade de Ciências Farmacêuticas da UNESP-Araraquara e que é parte integrante do NAC (Núcleo de Atendimento à Comunidade). Por ser vinculada à uma instituição pública ela serve como modelo para toda a comunidade, além de ser um estabelecimento de ensino, pesquisa e extensão. Por isso, ela tem o compromisso de cumprir com todas as exigências legais de maneira exemplar, garantindo a qualidade dos produtos manipulados. Realizou-se a revisão e adequação dos Procedimentos Operacionais Padrão (POPs) presente no Manual de Boas Práticas de Manipulação da Farmácia-Escola, baseando-se nas diretrizes da RDC 67/07 (Anexo I - Boas Práticas de Manipulação em Farmácia) e também uma inspeção na rotina dos processos envolvidos na manipulação e dispensação dos produtos manipulados. Fez-se a aplicação do Roteiro de Inspeção para Farmácia - Anexo VII da RDC 67/07 com a finalidade de constatar e avaliar o cumprimento das Boas Práticas de Manipulação em Farmácias (BPMF). Verificou-se que a Farmácia-Escola ainda não está em conformidade com todos os critérios estabelecidos pela RDC 67/07, mas que mesmo com as dificuldades enfrentadas para se adequar ela atende à quase todos os itens considerados imprescindíveis. Segundo as farmacêuticas responsáveis, medidas corretivas vêm sendo estudadas para que aos poucos todos os itens constantes na Resolução em questão sejam cumpridos.

Desenvolvimento e validação de método bioanalítico aplicado em estudo de farmacocinética pré-clínica e ensaio preliminar de segurança de novo derivado de tiazolidinodiona com atividade antiinflamatória - LYSO-07

Pós-graduação em Ciências Farmacêuticas - FCFAR

Intracellular Reactive Oxygen Species Production by Polymorphonuclear Leukocytes in Bovine Leukemia Virus-Infected Dairy Cows

The present study assesses the oxidative burst activity from polymorphonuclear leukocytes (PMNLs) from bovine leukemia virus (BLV)-infected cows. Fifteen clinically healthy cows were divided into serologically positive cows without any hematological alteration, serologically positive animals with persistent lymphocytosis (PL) and healthy serologically negative cows. The oxidative burst activity from the PMNLs was evaluated by now cytometry using 2',7'-dichlorofluorescein diacetate as a probe. PMNLs from each cow were incubated with heat-killed Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) to stimulate oxidative burst activity. The results of the present work showed no significant difference in the oxidative burst activity without any stimulus and elicited by S. caucus. Conversely, a decrease in the oxidative burst index induced by E. coli in PMNLs was observed in BLV-infected cows.

Evaluation of cytotoxic, genotoxic and antigenotoxic potential of Solanum lycocarpum fruits glicoalkaloid extract in V79 cells

Solanum lycocarpum St.-Hil (Solanaceae) is a hairy shrub or small much-branched tree of the Brazilian Cerrado, popularly known as "fruit-of-wolf". Considering that the induction of chromosomal mutations is involved in the process of carcinogenesis, and that S. lycocatpum is often used in folk medicine, it becomes relevant to study its effect on genetic material. In this sense, the aim of present study was to determine the possible cytotoxic, genotoxic and antigenotoxic potentials of S. lycocarpum fruits glycoalkaloid extract (SL) in Chinese hamster lung fibroblasts (V79 cells). The cytotoxicity was evaluated by the colony forming assay, apoptosis and necrosis assay. Trypan blue exclusion dye method and mitotic index. Genotoxic and antigenotoxic potential were evaluated by comet and chromosomal aberrations assays. Four concentrations of SL (4, 8, 16 and 32 mu g/mL) were used for the evaluation of its genotoxic potential. The DNA damage-inducing agent methyl methanesulfonate (MMS, 221 mu g/mL) was utilized in combination with extract to evaluate a possible protective effect. The results showed that SL was cytotoxic at concentrations above 32 mu g/mL by the colony forming assay. For apoptosis and necrosis assay, the concentration of 64 mu g/mL of SL showed statistically significant increase in cell death by apoptosis and necrosis, while the concentrations of 128 and 256 mu g/mL of SL demonstrated statistically significant increase in cell death by necrosis, compared with the control group. Analysis of cell viability by Trypan blue exclusion indicated >96% viability for treatments with concentrations up to 32 mu g/mL of SL No significant differences in MI were observed between cultures treated with different concentrations of 51 (4, 8, 16 and 32 mu g/mL) alone or in combination with MMS and the negative control, indicating that these treatments were not cytotoxic. The comet and chromosomal aberrations assays revealed that SL does not display genotoxic activity. Moreover, the different concentrations of SL showed protective effect against both genomic and chromosomal damages induced by MMS. (C) 2012 Elsevier Ltd. All rights reserved.