830 resultados para Brothers, Kent


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Este trabalho foi desenvolvido de junho de 2004 a maio de 2005, objetivando o reconhecimento de espécies de coleobrocas (Insecta: Coleoptera) que se encontram associadas a pomar comercial de manga (Mangifera indica) das variedades Tommy Atkins, Keitt, Kent e Palmer, no município de José de Freitas, Estado do Piauí. Foram instaladas duas armadilhas etanólicas modelo Carvalho 47 em cada área das referidas variedades e realizadas coletas semanais. As coleobrocas foram separadas dos resíduos vegetais, secas sob lâmpada e quantificadas. Posteriormente, exemplares de cada morfoespécie coletada foram identificados. Coleobrocas das famílias Bostrichidae, Cerambycidae, Curculionidae estão associadas às variedades de manga cultivadas no município de José de Freitas, Estado do Piauí, onde se destacam as espécies Hylettus seniculus (Germar) (Coleoptera: Cerambycidae), Hypothenemus sp. 1 e sp. 2. (Coleoptera: Curculionidae: Scolytinae), apresentando maior expressão numérica e variedade de morfoespécies durante o período de menor precipitação pluviométrica, fator correlacionado positivamente à família Cerambycidae.

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Given the cost constraints of the European health-care systems, criteria are needed to decide which genetic services to fund from the public budgets, if not all can be covered. To ensure that high-priority services are available equitably within and across the European countries, a shared set of prioritization criteria would be desirable. A decision process following the accountability for reasonableness framework was undertaken, including a multidisciplinary EuroGentest/PPPC-ESHG workshop to develop shared prioritization criteria. Resources are currently too limited to fund all the beneficial genetic testing services available in the next decade. Ethically and economically reflected prioritization criteria are needed. Prioritization should be based on considerations of medical benefit, health need and costs. Medical benefit includes evidence of benefit in terms of clinical benefit, benefit of information for important life decisions, benefit for other people apart from the person tested and the patient-specific likelihood of being affected by the condition tested for. It may be subject to a finite time window. Health need includes the severity of the condition tested for and its progression at the time of testing. Further discussion and better evidence is needed before clearly defined recommendations can be made or a prioritization algorithm proposed. To our knowledge, this is the first time a clinical society has initiated a decision process about health-care prioritization on a European level, following the principles of accountability for reasonableness. We provide points to consider to stimulate this debate across the EU and to serve as a reference for improving patient management.

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[spa]En este artículo planteamos que significaron los trabajos de los arquitectos Ramon y Antoni Puig Gairalt, que abarcan desde la primera década del siglo XX hasta el año 1937 y que aún perviven en muchas de las localidades del territorio catalán donde intervinieron. Hablamos en plural de los Puig Gairalt porque fueron dos hermanos, Ramon y Antoni, aunque en L'Hospitalet de Llobregat las intervencions corresponden mayoritariamente a Ramon Puig Gairalt. En la actualidad muchas de las obras perduran y, como valores patrimoniales, han llegado hasta nosotros. Como es bien sabido, el patrimonio de muchas poblaciones y ciudades forma parte de la memoria con la que una colectividad se identifica. A lo largo del tiempo, han ido conformando su paisaje urbano y cualquier colectividad que transita por su territorio, establece un vínculo muy directo sea éste o no de carácter monumental porque de hecho se ha convertido en signo de su identidad.

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Individuals with an inherited deficiency in gonadotropin-releasing hormone (GnRH) have impaired sexual reproduction. Previous genetic linkage studies and sequencing of plausible gene candidates have identified mutations associated with inherited GnRH deficiency, but the small number of affected families and limited success in validating candidates have impeded genetic diagnoses for most patients. Using a combination of exome sequencing and computational modeling, we have identified a shared point mutation in semaphorin 3E (SEMA3E) in 2 brothers with Kallmann syndrome (KS), which causes inherited GnRH deficiency. Recombinant wild-type SEMA3E protected maturing GnRH neurons from cell death by triggering a plexin D1-dependent (PLXND1-dependent) activation of PI3K-mediated survival signaling. In contrast, recombinant SEMA3E carrying the KS-associated mutation did not protect GnRH neurons from death. In murine models, lack of either SEMA3E or PLXND1 increased apoptosis of GnRH neurons in the developing brain, reducing innervation of the adult median eminence by GnRH-positive neurites. GnRH neuron deficiency in male mice was accompanied by impaired testes growth, a characteristic feature of KS. Together, these results identify SEMA3E as an essential gene for GnRH neuron development, uncover a neurotrophic function for SEMA3E in the developing brain, and elucidate SEMA3E/PLXND1/PI3K signaling as a mechanism that prevents GnRH neuron deficiency.

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Between 1857 and 1859 Alexandre Dumas published eleven tales from the Brothers Grimm and Hans Christian Andersen's collections in his magazine Le Monte-Cristo. The texts have a particular status, between translation and rewriting. Dumas includes them in a causerie (chat) with the readers of his magazine, and they are framed in a story where an adult tells tales to children. This results in several modifications of the originals-such as the addition of explicative comments-which I study through a comparison of "Petit-Jean et Gros-Jean" and Andersen's "Little Claus and Big Claus." Underrated and forgotten, Dumas's tales are nonetheless representative of his particular style and bear witness to his storytelling skills. They also show similarities between Dumas and Andersen, who actually became acquainted in Paris in 1843.

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OBJECTIVE: We examined the influence of clinical, radiologic, and echocardiographic characteristics on antithrombotic choice in patients with cryptogenic stroke (CS) and patent foramen ovale (PFO), hypothesizing that features suggestive of paradoxical embolism might lead to greater use of anticoagulation. METHODS: The Risk of Paradoxical Embolism Study combined 12 databases to create the largest dataset of patients with CS and known PFO status. We used generalized linear mixed models with a random effect of component study to explore whether anticoagulation was preferentially selected based on the following: (1) younger age and absence of vascular risk factors, (2) "high-risk" echocardiographic features, and (3) neuroradiologic findings. RESULTS: A total of 1,132 patients with CS and PFO treated with anticoagulation or antiplatelets were included. Overall, 438 participants (39%) were treated with anticoagulation with a range (by database) of 22% to 54%. Treatment choice was not influenced by age or vascular risk factors. However, neuroradiologic findings (superficial or multiple infarcts) and high-risk echocardiographic features (large shunts, shunt at rest, and septal hypermobility) were predictors of anticoagulation use. CONCLUSION: Both antithrombotic regimens are widely used for secondary stroke prevention in patients with CS and PFO. Radiologic and echocardiographic features were strongly associated with treatment choice, whereas conventional vascular risk factors were not. Prior observational studies are likely to be biased by confounding by indication.

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L’objectiu principal d’aquest treball és assumir el que podria ser un encàrrec real d’un text jurídic. Així que, en aquest treball es tradueix un testament. Els testaments són documents a través dels quals una persona disposa els seus béns per tal que després de la seva mort una altra se’n faci càrrec. El testament escollit ha estat el de Charles Robert Darwin, que va morir el 19 d’abril de 1882 a Down, en el comptat de Kent, Anglaterra, on hi visqué 40 anys, des del 1842 fins la seva mort. Aquest testament té unes particularitats concretes, ja que fa uns 190 anys que es va firmar. El dret successori anglès, regit per la Llei de successions de protecció de la família i tuïció de 1975 és molt diferent del dret successori català. Així doncs, coneixerem les diferències entre el dret successori català i l’anglès. També, veurem tots passos que han estat necessaris per portar a terme aquest treball.

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[spa] Se analiza la "S. A. de Extractos Tánicos" fundada en el Pueblo Nuevo de Barcelona en el año 1909 por los hermanos Pedro Pablo, Fernando y Carlos de Corral y Tomé. El matrimonio de Pedro Pablo de Corral y Tomé con la rosarina Clara Margarita Casado Sastre nos permite reconstruir la vinculación familiar y empresarial entre la empresa barcelonesa dedicada a la importación de la "quiebra hacha" durante la primera mitad del siglo XX, y la "S. A. Carlos Casado Limitada, Compañía de Tierras", dedicada al quebracho colorado del Gran Chaco latinoamericano.

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[spa]Este trabajo analiza el papel desempeñado por la revista El Arte de Curtir, creada en el año 1909 en la ciudad de Barcelona por los hermanos Pedro Pablo, Fernando y Carlos de Corral y Tomé, cuya Fábrica de Extractos Curtientes dedicada al quebracho colorado paraguayo fue la base de organización del extracto tánico utilizado en Cataluña para la curtición.

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EONIA is a market based overnight interest rate, whose role as the starting point of the yield curve makes it critical from the perspective of the implementation of European Central Bank´s common monetary policy in the euro area. The financial crisis that started in 2007 had a large impact on the determination mechanism of this interest rate, which is considered as the central bank´s operational target. This thesis examines the monetary policy implementation framework of the European Central Bank and changes made to it. Furthermore, we discuss the development of the recent turmoil in the money market. EONIA rate is modelled by means of a regression equation using variables related to liquidity conditions, refinancing need, auction results and calendar effects. Conditional volatility is captured by an EGARCH model, and autocorrelation is taken into account by employing an autoregressive structure. The results highlight how the tensions in the initial stage of the market turmoil were successfully countered by ECB´s liquidity policy. The subsequent response of EONIA to liquidity conditions under the full allotment liquidity provision procedure adopted after the demise of Lehman Brothers is also established. A clear distinction in the behavior of the interest rate between the sub-periods was evident. In the light of the results obtained, some of the challenges posed by the exit-strategy implementation will be addressed.

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Kirjallisuusarvostelu

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Johdanto ; Tutkimusnäkökulmia musiikkiteknologiaan ; Musiikkiteknologiat sosiaalisina teknologioina ; Musiikillisia teknokulttuureja? ; Tekniikat - musiikin tuottamisen ja kuuntelemisen käytännöt ; Musiikin tuottamisen tekniikat tietokoneohjelmilla ; Musiikin tekeminen Reason-ohjelmistolla ; Kaksi Reasonin käyttäjää ja musiikin tuottamisen tekniikat ; Masterointia Reasonilla ; Yhteisöllisyys.

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In this postgraduate thesis the focus is on two documentary films, Renaud Brothers's Dope Sick Love (2005) and Joonas Neuvonen's Reindeerspotting (2010). In both of these films, addicts are on limelight. The directors of both films follow addicts and their everyday lives on streets with handheld cameras. This thesis will analyze and compare the narratives of these addicts. Do these documentaries affirm to the existing conventions, according to which representations of addicts and addiction are always either miraculous survival stories or stories, which always end up in utter decadence. The main questions this thesis proposes, are how addicts and their narratives are being handled in the two case study films, and how the drug cultures depicted in the films differ from each other. What changes between New York City and Rovaniemi, Northern Finland, and what remains the same. The academic and theoretical framework of this thesis consists of Susanna Helke's doctoral thesis Nanookin jälki, where the history of documentary films' methods and approaches are discussed. Additionally, the thinking is heavily informed by such poststructuralist writers as Roland Barthes, Michel Foucault, Louis Althusser, Stuart Hall and Chris Weedon.