837 resultados para AML Schema (XSD)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Com o movimento da Matemática Moderna, a partir de 1950, o ensino da matemática passou a enfatizar o simbolismo e a exigir dos alunos grandes abstrações, distanciando a matemática da vida real. O que se percebe é que o aluno formado por este currículo aprendeu muito pouco de geometria e não consegue perceber a relação deste conteúdo com sua realidade. Por outro lado, o professor que não conhece geometria não consegue perceber a beleza e a importância que a mesma possui para a formação do cidadão. A geometria estimula a criança a observar, perceber semelhanças, diferenças e a identificar regularidades. O objetivo deste trabalho é identificar o nível de conhecimento dos alunos do Centro Específico de Formação e Aperfeiçoamento ao Magistério (CEFAM), futuros professores da 1ª a 4ª séries do Ensino Fundamental do Estado de São Paulo, quanto aos conceitos de ponto, reta, plano, ângulos, polígonos e circunferências e também verificar as contribuições do computador para a construção de conceitos geométricos. Para atingir esses objetivos, foi desenvolvida uma pesquisa com 30 alunos do CEFAM de Presidente Prudente-SP, na qual, com base no diagnóstico das dificuldades de aprendizagem, organizaram e desenvolveram-se os momentos de formação, que utilizaram o computador como ferramenta de aprendizagem e projetos de trabalho tendo como aporte teórico a abordagem construcionista. O futuro professor que não dominar a geometria e não perceber sua relação com a natureza não conseguirá contribuir para o desenvolvimento do pensamento geométrico da criança. Esse pensamento é que permite a criança observar, compreender, descrever e representar, de forma organizada, o mundo em que vive.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Este experimento foi realizado com o objetivo de investigar os efeitos de diferentes granulometrias, expressa em Diâmetro Geométrico Médio (DGM) do milho (0,336mm, 0,585mm, 0,856 mm e 1,12 mm) de dietas fornecidas na forma farelada (FAR) e peletizada (PEL), no desempenho e no rendimento de carcaça e de cortes de frangos de corte de 21 a 42 dias de idade. Dietas FAR, produzidas com DGM de 0,336 mm resultaram em um menor consumo (p<0,001), ganho de peso (p<0,001) e pior conversão alimentar (p<0,001) do que as PEL de mesmo DGM. Os demais DGM não mostraram diferenças entre ração FAR e PEL. Quando avaliada somente a granulometria, observou-se que o aumento no DGM melhorou o ganho de peso linearmente e de forma quadrática o consumo e a conversão alimentar. Não houve influência da forma física ou DGM em rendimento de carcaça e rendimento de perna+coxa. Porém foi verificada uma redução em rendimento de peito com DGM 0,336 mm (p<0,001), na forma FAR.
Analytical and Monte Carlo approaches to evaluate probability distributions of interruption duration
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Regulatory authorities in many countries, in order to maintain an acceptable balance between appropriate customer service qualities and costs, are introducing a performance-based regulation. These regulations impose penalties-and, in some cases, rewards-that introduce a component of financial risk to an electric power utility due to the uncertainty associated with preserving a specific level of system reliability. In Brazil, for instance, one of the reliability indices receiving special attention by the utilities is the maximum continuous interruption duration (MCID) per customer.This parameter is responsible for the majority of penalties in many electric distribution utilities. This paper describes analytical and Monte Carlo simulation approaches to evaluate probability distributions of interruption duration indices. More emphasis will be given to the development of an analytical method to assess the probability distribution associated with the parameter MCID and the correspond ng penalties. Case studies on a simple distribution network and on a real Brazilian distribution system are presented and discussed.
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A case of primary myiasis in a dog caused by Phaenicia eximia (Robineau-Desvoidy) in Brazil is presented. A young and healthy female dog, Canis familiaris, approximate to 10 d old and still under maternal care, was found to have several eggs and Is: instars larvae in its abdomen and urogenital regions. Samples were collected in Campinas, São Paulo, and transferred to the laboratory for rearing and identification. A comparative analysis of the mitochondrial DNA (mtDNA) with 12 restriction enzymes in 2 sampled populations of P. eximia collected in different hosts (live dog and bovine carcass) and in the same locality revealed that 4, EcoRI, EcoRV, HaeIII, and MspI were suitable for detecting mtDNA markers in the 2 populations.
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A simple and sensitive chemiluminescence assay for the demonstration of the activity of intracellular myeloperoxidase (MPO) is described, which is useful for the distinction between myeloid and lymphoid commitment in blasts from acute leukemia patients. When the cut-off point was settled at 13 mV of chemiluminescence all cases of acute myeloid leukemia (AML) were distinguished from those of acute lymphoid leukemia. In addition, this technique was able to demonstrate MPO activity in AML poorly differentiated (FAB-M0) which usually does not stain for MPO in classical cytochemistry preparations and could be negative also by immunocytochemistry with anti-MPO monoclonal antibody. Therefore the method here described presented a higher sensitivity than the immunocytochemistry procedure with anti-MPO.
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Leukemia is a genetic disease from a noncontrolled abnormal process of the hematopoietic cells' differentiation and proliferation. Some alterations of structure and number of chromosomes have been well and specifically observed in leukemia. The detection of these alterations is highly significant in providing the patients' diagnosis, prognosis and treatment as well as the understanding of the genetic bases of this disease. The purpose of this work is to study some chromosomal alterations in peripheral blood and/or bone marrow in patients with different leukemia types by means of conventional cytogenetic techniques, and also to investigate the presence of BCR/ABL gene rearrangement and some alterations in chromosome 20 by the FISH technique. Samples of peripheral blood and/or bone marrow of 28 patients, who were not under chemoor radio-therapeutic treatment, were studied: 15 with CML, 11 with AML and 2 with ALL. The alteration most frequent was t(9;22) in the CML, whose presence or absence was related to a good or bad prognosis, respectively. A case of AMI showed inv(16)(p13q22), related to a good prognosis. Some alterations not reported previously in the literature were found, such as the trisomy in chromosome 2 associated to chromosome Ph showing some disease progress in one of the CML cases and t(5;16)(q13;q22) in an AML patient. One of the cases was submitted to an allogeneic hone marrow transplant. The monitoring after the 23 rd day of transplant, detected 95% of the donor cells suggesting the procedure had succeeded. Two patients, an AMI and the other ALL, showed trisomy of chromosome 20 in the neoplastic cells. The results showed the importance of the cytogenetic analysis in relation to leukemia, its direct benefits to the patients and the biological mechanisms involved in this disease. They also allowed the introduction in the Genetic Service of FAMERP techniques to obtain the bone marrow metaphases and the FISH technique.
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Plants that possess a diuretic effect are widely used by people in the treatment of some important diseases as edema and hypertension. The objective of this work was to study the effects of pitanga and jambos aqueous extracts (AE) about the arterial pressure (AP) and urinary flow (V) in normotensive and anesthetized rats. The AE were prepared for the decoction method and administrated for intragastric way in different concentrations: 10%, 15%, 20% and 25%. These concentrations corresponded respectively at doses of 56, 94, 145, 172 mg of pitanga dried extract /Kg and 44, 73, 83, 95 mg of jambos dried extract/Kg. The animals were divided in nine groups with seven individuals (n=7): control (C), P-10%, P-15%, P-20%, P-25%, J-10%, J-15%, J-20% and J-25%. The rats were anesthetized (hypnol 3%) and submitted to tracheotomy. The left carotide artery was catheterized to measure the AP through a mercury manometer, in periods of 15 minutes. The bladder was catheterized for urine collection and to measure the V, in periods of 30 minutes. The experimental protocol was divided in four periods of 30 minutes each: basal (to evaluate of the basal parameters) and experimental (Exp) 1, 2 and 3 (after the administration of the AE). The results were analyzed for ANOVA and Tukey (X±SD, p<0.05). In the C group did have not alteration of the AP basal but the V basal increased. In the experimental groups (AE of P and J) had significative decline in the AP basal: 34% (P-10%), 20% (P-15%), 21% (P-20%), 31% (P-25%), 24% (J-10%), 20% (J-15%) 16% (J-20%) and 29% (J-25%). Moreover, the administration of AE increased the V basal in: 280% (P-15%) and 192% (J-20%). The results showed that the plants evaluated are hypotensive and diuretic.
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Automatic inspection of petroleum well drilling has became paramount in the last years, mainly because of the crucial importance of saving time and operations during the drilling process in order to avoid some problems, such as the collapse of the well borehole walls. In this paper, we extended another work by proposing a fast petroleum well drilling monitoring through a modified version of the Optimum-Path Forest classifier. Given that the cutting's volume at the vibrating shale shaker can provide several information about drilling, we used computer vision techniques to extract texture informations from cutting images acquired by a digital camera. A collection of supervised classifiers were applied in order to allow comparisons about their accuracy and effciency. We used the Optimum-Path Forest (OPF), EOPF (Efficient OPF), Artificial Neural Network using Multilayer Perceptrons (ANN-MLP) Support Vector Machines (SVM), and a Bayesian Classifier (BC) to assess the robustness of our proposed schema for petroleum well drilling monitoring through cutting image analysis.
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Aiming to ensure greater reliability and consistency of data stored in the database, the data cleaning stage is set early in the process of Knowledge Discovery in Databases (KDD) and is responsible for eliminating problems and adjust the data for the later stages, especially for the stage of data mining. Such problems occur in the instance level and schema, namely, missing values, null values, duplicate tuples, values outside the domain, among others. Several algorithms were developed to perform the cleaning step in databases, some of them were developed specifically to work with the phonetics of words, since a word can be written in different ways. Within this perspective, this work presents as original contribution an optimization of algorithm for the detection of duplicate tuples in databases through phonetic based on multithreading without the need for trained data, as well as an independent environment of language to be supported for this. © 2011 IEEE.
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The nitrogen fertilization is an important practice to reach high productivity, however, nitrogen high level can cause lodging and make the plants more sensitive to disease. Numerous studies has demonstrate that a lot of grasses accumulate silicon at its tissues, and the biggest part of this element is deposited on the leaf, that would work like a mechanical barrier to diseases come in. However, high levels of nitrogen can reduce the silica deposition at the plants. The objective of this study was to evaluate silicon and nitrogen content in shoot and silica deposition in upland rice leaf as a result of Si and N levels. The experimental design used was completely randomized in factorial schema 3 x 2 with five replications. The treatments consisted from levels of N (5, 75 and 150 mg dm-3 of soil) in urea form and two levels of SiO2 (0 e 400 mg dm-3) in calcium silicate form (Wollastonita). The increased of urea fertilization reduced the silicon content of rice plants and the silica deposition at the external cells wall the epidermal rice leafs.
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Currently, many museums, botanic gardens and herbariums keep data of biological collections and using computational tools researchers digitalize and provide access to their data using data portals. The replication of databases in portals can be accomplished through the use of protocols and data schema. However, the implementation of this solution demands a large amount of time, concerning both the transfer of fragments of data and processing data within the portal. With the growth of data digitalization in institutions, this scenario tends to be increasingly exacerbated, making it hard to maintain the records updated on the portals. As an original contribution, this research proposes analysing the data replication process to evaluate the performance of portals. The Inter-American Biodiversity Information Network (IABIN) biodiversity data portal of pollinators was used as a study case, which supports both situations: conventional data replication of records of specimen occurrences and interactions between them. With the results of this research, it is possible to simulate a situation before its implementation, thus predicting the performance of replication operations. Additionally, these results may contribute to future improvements to this process, in order to decrease the time required to make the data available in portals. © Rinton Press.
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This study sought to evaluate motor development in children aged 6 to 11 years with learning difficulties and school characteristics of delayed motor development, before and after application of a motor intervention program. The sample consisted of 28 children with a mean age of 107.21 ± 16.56 months, who were evaluated by the Motor Development Scale and received motor intervention for 6 months, followed by reassessment. We observed a statistically significant difference between the average of the motor activity ratios in all areas of the evaluation and reevaluation. Also verified in the evaluation were the concentration ratios of children with motor activity greater than or equal to 80 and there was a revaluation increase in this concentration on re-evaluation, the areas with the greatest increase in concentration and significant differences being: Body Schema, Space and temporal Organization. In the overall evaluation of MDS, most children presented the classification of low normal. However, in the reassessment most have evolved into the average normal, only 4 of themremaining in the same classification. Therefore, in this study, children with learning disabilities also showed motor deficits and the intervention applied contributed to an increase in the motor ratios with consequent improvement in motor development. Besides psychopedagogical asistance, it is essential to reassess them and if necessary apply the intervention in the motor development of children with learning difficulties.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)