From snowflakes to sandcastles : a child's year in words and pictures. 'De los copos de nieve a los castillos de arena : un curso de palabras y dibujos'.

Imágenes en miniatura ilustran las doce palabras que describen cada mes del año y van acompañadas de preguntas para animar a los niños a buscar y encontrar los distintos objetos que están en la otra página, ilustrada con las imágenes de los objetos antes mencionados. El nombre del mes aparece en la parte superior derecha de cada página seguido de una lista de objetos que no siempre tienen una conexión lógica con el mes.

Happy!

Presenta imágenes de bebés de una amplia gama de grupos étnicos para compartir con los niños las experiencias de cada día : probando, oliendo, tocando buscando, escuchando.

AQA GCSE Performing Arts.

Texto que, además de ayudar al alumno a adquirir los conocimientos de las asignaturas para obtener el General Certificate of Secondary Education (GCSE) de esta especificación , permite una participación activa en los procesos de las artes escénicas. El curso presenta las disciplinas esenciales para la comprensión de las artes escénicas. Se trabaja a través de una serie de resúmenes prácticos y de elaborar los proyectos para el portafolio. Desarrolla el conocimiento y la comprensión de la industria de esta especialidad a nivel local y nacional, los atributos personales, incluyendo la confianza en sí mismo, la resistencia, la perseverancia, la autodisciplina y el compromiso. Proporciona una base sólida para el progreso en las artes escénicas, como son estudios de teatro y temas genéricos, incluyendo la danza y la música. Facilita una base para el trabajo de diseño en conjunto, vestuario y utilería y elementos técnicos como en iluminación y sonido. Presenta una amplia gama de habilidades personales y de organización para el lugar de trabajo.

L'éducation au développement durable : de l'école au campus. 'La educación en el desarrollo sostenible : de la escuela al campus'.

Basado en un Coloquio Internacional con el mismo título celebrado en L'École des Mines d'Albi, 25-27 de junio de 2008

Stories of ourselves : the University of Cambridge International Examinations anthology of stories in english.

Antología de relatos de escritores de diferentes países y culturas, como Charles Dickens, H.G. Wells, Virginia Woolf, Graham Greene, V.S. Naipaul, Raymond Carver, Jhumpa Lahiri y Annie Proulx. Su contenido se adapta al estudio del CIE, IGCSE y a los exámenes del nivel AS y nivel A de literatura en inglés.

Edexcel IGCSE Further Pure Mathematics: Student Book.

Este libro desarrolla los conocimientos básicos de matemáticas para aprobar los exámenes de Edexcel IGCSE nivel de enseñanza secundaria. Los temas del libro son : índices y funciones logarítmicas (reglas de índices, escribir una expresión como logaritmo, leyes de los logaritmos), la función al cuadrado ( resolviendo ecuaciones al cuadrado), igualdades y desigualdades (dividiendo un polinomio), gráficos y funciones (usando gráficos de funciones para resolver ecuaciones, dibujando las curvas de las funciones) series (sumando los términos de una secuencia aritmética), usando vectores para describir la posición de un punto, cálculo, trigonometría (usando las reglas del seno y el coseno).

A comparison of scores of deaf and hearing children on the Hiskey Test of learning ability and on performance scales

This paper discusses the Hiskey Test of learning ability and its use on hearing impaired and normal hearing children.

Interdependency and care over the lifecourse

Interdependency and Care over the Lifecourse draws upon theories of time and space to consider how informal care is woven into the fabric of everyday lives and is shaped by social and economic inequalities and opportunities. The book comprises three parts. The first explores contrasting social and economic contexts of informal care in different parts of the world. The second looks at different themes and dynamics of caring, using fictional vignettes of illness and health, child care, elderly care and communities of care. The book examines the significance to practices of care throughout the lifecourse of: understandings and expectations of care emotional exchanges involved in care memories and anticipations of giving and receiving care the social nature of the spaces and places in which care is carried out the practical time-space scheduling necessary to caring activities. Finally the authors critically examine how the frameworks of caringscapes and carescapes might be used in research, policy and practice. A working example is provided. This book will be of interest to students and researchers of care work, health and social care, geography, sociology of the family and social policy as well as those in business and policy communities trying to gain an understanding of how work and informal care interweave

Zea mays annexins modulate cytosolic free Ca2+ and generate a Ca2+-permeable conductance

Regulation of reactive oxygen species and cytosolic free calcium ([Ca2+](cyt)) is central to plant function. Annexins are small proteins capable of Ca2+-dependent membrane binding or membrane insertion. They possess structural motifs that could support both peroxidase activity and calcium transport. Here, a Zea mays annexin preparation caused increases in [Ca2+] cyt when added to protoplasts of Arabidopsis thaliana roots expressing aequorin. The pharmacological profile was consistent with annexin activation (at the extracellular plasma membrane face) of Arabidopsis Ca2+-permeable nonselective cation channels. Secreted annexins could therefore modulate Ca2+ influx. As maize annexins occur in the cytosol and plasma membrane, they were incorporated at the intracellular face of lipid bilayers designed to mimic the plasma membrane. Here, they generated an instantaneously activating Ca2+-permeable conductance at mildly acidic pH that was sensitive to verapamil and Gd3+ and had a Ca2+-to-K+ permeability ratio of 0.36. These results suggest that cytosolic annexins create a Ca2+ influx pathway directly, particularly during stress responses involving acidosis. A maize annexin preparation also demonstrated in vitro peroxidase activity that appeared independent of heme association. In conclusion, this study has demonstrated that plant annexins create Ca2+-permeable transport pathways, regulate [Ca2+] cyt, and may function as peroxidases in vitro.

Rapid radiation in spiny lobsters (Palinurus spp) as revealed by classic and ABC methods using mtDNA and microsatellite data

Background: Molecular tools may help to uncover closely related and still diverging species from a wide variety of taxa and provide insight into the mechanisms, pace and geography of marine speciation. There is a certain controversy on the phylogeography and speciation modes of species-groups with an Eastern Atlantic-Western Indian Ocean distribution, with previous studies suggesting that older events (Miocene) and/or more recent (Pleistocene) oceanographic processes could have influenced the phylogeny of marine taxa. The spiny lobster genus Palinurus allows for testing among speciation hypotheses, since it has a particular distribution with two groups of three species each in the Northeastern Atlantic (P. elephas, P. mauritanicus and P. charlestoni) and Southeastern Atlantic and Southwestern Indian Oceans (P. gilchristi, P. delagoae and P. barbarae). In the present study, we obtain a more complete understanding of the phylogenetic relationships among these species through a combined dataset with both nuclear and mitochondrial markers, by testing alternative hypotheses on both the mutation rate and tree topology under the recently developed approximate Bayesian computation (ABC) methods. Results: Our analyses support a North-to-South speciation pattern in Palinurus with all the South-African species forming a monophyletic clade nested within the Northern Hemisphere species. Coalescent-based ABC methods allowed us to reject the previously proposed hypothesis of a Middle Miocene speciation event related with the closure of the Tethyan Seaway. Instead, divergence times obtained for Palinurus species using the combined mtDNA-microsatellite dataset and standard mutation rates for mtDNA agree with known glaciation-related processes occurring during the last 2 my. Conclusion: The Palinurus speciation pattern is a typical example of a series of rapid speciation events occurring within a group, with very short branches separating different species. Our results support the hypothesis that recent climate change-related oceanographic processes have influenced the phylogeny of marine taxa, with most Palinurus species originating during the last two million years. The present study highlights the value of new coalescent-based statistical methods such as ABC for testing different speciation hypotheses using molecular data.

Annexins: multifunctional components of growth and adaptation

Plant annexins are ubiquitous, soluble proteins capable of Ca2+-dependent and Ca2+-independent binding to endomembranes and the plasma membrane. Some members of this multigene family are capable of binding to F-actin, hydrolysing ATP and GTP, acting as peroxidases or cation channels. These multifunctional proteins are distributed throughout the plant and throughout the life cycle. Their expression and intracellular localization are under developmental and environmental control. The in vitro properties of annexins and their known, dynamic distribution patterns suggest that they could be central regulators or effectors of plant growth and stress signalling. Potentially, they could operate in signalling pathways involving cytosolic free calcium and reactive oxygen species.

Arabidopsis annexin1 mediates the radical-activated plasma membrane Ca2+ - and K+ -permeable conductance in root cells

Plant cell growth and stress signaling require Ca2+ influx through plasma membrane transport proteins that are regulated by reactive oxygen species. In root cell growth, adaptation to salinity stress, and stomatal closure, such proteins operate downstream of the plasma membrane NADPH oxidases that produce extracellular superoxide anion, a reactive oxygen species that is readily converted to extracellular hydrogen peroxide and hydroxyl radicals, OH_. In root cells, extracellular OH_ activates a plasma membrane Ca2+-permeable conductance that permits Ca2+ influx. In Arabidopsis thaliana, distribution of this conductance resembles that of annexin1 (ANN1). Annexins are membrane binding proteins that can form Ca2+-permeable conductances in vitro. Here, the Arabidopsis loss-of-function mutant for annexin1 (Atann1) was found to lack the root hair and epidermal OH_-activated Ca2+- and K+-permeable conductance. This manifests in both impaired root cell growth and ability to elevate root cell cytosolic free Ca2+ in response to OH_. An OH_-activated Ca2+ conductance is reconstituted by recombinant ANN1 in planar lipid bilayers. ANN1 therefore presents as a novel Ca2+-permeable transporter providing a molecular link between reactive oxygen species and cytosolic Ca2+ in plants.

Lorrie Moore: Mo(o)re than an interim assessment

Lorrie Moore has long shed the image of the precocious talent who won the Seventeen story prize with her first submission as a nineteen-year-old undergraduate, but there is still a sense that her best work may be yet to come. In that respect, this mini special issue represents by no means the final word on Moore, but rather an interim assessment of a career that is already substantial and that promises much more to come. Together these three essays (and introduction) offer a coherent and striking exploration of Moore's work that develops new directions for future criticism and will help cement her growing reputation as one of the most original and distinctive contemporary writers. They sometimes circle around the same stories, even the same quotations, reading them in a variety of frames and picking up (and at) the nuances of Moore's sustained wordplay and careful documenting of space, of identity, of gender. Thus these essays work together rather than separately, layering over multiple understandings of Moore's incisive American literature.