Una aproximació a l’impuls econòmic de la Universitat de Girona sobre l’entorn local

Des d’una perspectiva econòmica, les institucions universitàries es poden concebre com a gestores del coneixement: organitzacions que utilitzen recursos (inputs) per generar i transferir coneixements (outputs). Aquest enfocament permet sintetitzar dos efectes econòmics que afecten el territori. En primer lloc, la gestió del coneixement esdevé un factor vital per a la competitivitat del territori. El coneixement afecta tant el sistema productiu local (ja que les bases del creixement econòmic incideixen sobre la productivitat) com l’eficiència actuali futura de les organitzacions locals (ja que actua com a element d’atracció, de creació i de manteniment d’activitats econòmiques). En segon lloc, l’activitat universitària afecta directament i indirectament la demanda locali estimula la producció de béns i de serveis locals. La universitat actua, doncs, de motor arrossegador del’economia local, ja que repercuteix sobre el nivell de riquesa i d’ocupació del territori on es troba ubicada. Demanera semblant a altres universitats catalanes (universitats de Lleida, Rovira i Virgili i de Vic), aquest treballvalora l’impacte de la Universitat de Girona (UdG) en l’economia de l’entorn. L’aproximació es fa des de duesvessants. D’una banda, s’utilitza la metodologia input-output per valorar l’impacte econòmic de la demandagenerada sobre el territori gironí. De l’altra, mitjançant un seguit d’indicadors, es mesura la sortida produïdaper la UdG i es contextualitza en el marc espanyol i de les comarques gironines

Identifying the Role of Final Consumption in Structural Path Analysis: An Application to Water Uses

The complexity of the connexions within an economic system can only be reliably reflected in academic research if powerful methods are used. Researchers have used Structural Path Analysis (SPA) to capture not only the linkages within the production system but also the propagation of the effects into different channels of impacts. However, the SPA literature has restricted itself to showing the relations among sectors of production, while the connections between these sectors and final consumption have attracted little attention. In order to consider the complete set of channels involved, in this paper we propose a structural path method that endogenously incorporates not only sectors of production but also the final consumption of the economy. The empirical application comprises water usages, and analyses the dissemination of exogenous impacts into various channels of water consumption. The results show that the responsibility for water stress is imputed to different sectors and depends on the hypothesis used for the role played by final consumption in the model. This highlights the importance of consumers’ decisions in the determination of ecological impacts. Keywords: Input-Output Analysis, Structural Path Analysis, Final Consumption, Water uses.

L'impacte econòmic de la Universitat de Lleida

La tendència descentralitzadora que ha caracteritzat els darrers anys la política universitària ha tingut, sens dubte, un impacte important sobre l’economia de les regions en les quals s’ha ubicat una universitat de nova creació. Els estudis de l’impacte econòmic de la universitat sobre el territori són un instrument important per justificar i incentivar la descentralització geogràfica de l’ensenyament superior. Sobretot en èpoques en què les rigideses pressupostàries exigeixen racionalitzar al màxim els nivells de despesa pública. Aquest estudi aplica la metodologia input-output per quantificar l’impacte que les activitats de la Universitat de Lleida han tingut sobre l’economia del territori. En concret, s’avaluen els impactes de la despesa de la mateixa Universitat, del professorat, de la resta del personal i dels estudiants. L’objectiu principal és arribar a conclusions sobre com un impuls exogen al territori genera producció, renda i ocupació en la mateixa regió.

Incidencia territorial de la política universitaria

La tendencia descentralizadora impulsada por la política universitaria española ha tenido, sin lugar a dudas, un impacto importante sobre la economía de las regiones en las que se ha asentado una Universidad de nueva creación. Los estudios del impacto económico de la Universidad sobre el área geográfica en la que se desenvuelve, son un importante instrumento para justificar e incentivar la descentralización geográfica de la educación superior, especialmente en tiempos en los que las rigideces presupuestarias exigen racionalizar al máximo los niveles de gasto público. Una de las técnicas habitualmente utilizadas para evaluar los efectos de la Universidad sobre la economía regional, es la basada en el análisis input-output. Dicho análisis estima el impacto total del gasto, incluyendo los efectos directos, los efectos indirectos y los efectos inducidos del consumo. La metodología input-output es precisamente, la que se aplica en este trabajo para poder cuantificar el impacto que las actividades de la Universidad de Lleida han tenido sobre la economía territorial.

Paperirullan kannatushihnan kestoiän pidentäminen

Työn tavoitteena oli selvittää kannatushihnapituusleikkurissa paperin rullaukseen käytettävän kannatushihnan kestoikään vaikuttavia tekijöitä ja ratkaisuja liian lyhyeen kestoikään liittyviin ongelmiin. Työssä selvitettiin ensin kannatushihnatyyppisen pituusleikkurin toimintaa ja tarkemmin sen rullausosaa ja rullausprosessin parametreja. Kannatushihnan kestoikään vaikuttavia tekijöitä on käsitelty kirjallisuuden ja kohdeyrityksessä olevan materiaalin perusteella. Seuraavaksi esitettiin ideoita kannatushihnan rakenteesta ja materiaaleista sekä vertailtiin niitä keskenään ja nykyiseen hihnan rakenteeseen. Työssä tehtiin nykyistä kannatushihnaa simuloiva kaksiulotteinen elementtimalli. Tämän elementtimallin mukaan pituusleikkurin telojen suunnassa epätasainen hihnan kuluminen johtuu hihnan paksuussuuntaisten jännitysten eroista. Hihnan kulkua arvioitiin kokeellisesti kahdella erityyppisellä hihnalla. Hihnan kulkuun eniten vaikutti esikiristysvoima, jota pienennettäessä kehänopeusero paperirullaa simuloivan kuormittavan telan ja hihnatelan välillä pieneni. Työssä löydettiin mahdollinen yhteys rullauksessa tulostietona saatavan datan sekä hihnan geometrian välille. Polyeteenivaahtomuovit ovat kitkansa puolesta lupaavia hihnan kitkapinnoitteen materiaaliksi. Toisaalta polyeteenivaahtomuovien mekaanisia ominaisuuksia ei juuri tunneta, eikä niitä ole käytetty kulutuskestoa vaativissa sovelluksissa. Hihnan ulkopinnan kulumismekanismia ei täysin tunneta.

WM Program manual

This manual describes how to run the new produced GUI C++ program that so called'WM' program. Section two describes the instructions of the program installation.Section three illustrates test runs description including running the program WM,sample of the input, output files, in addition to some generated graphs followed by the main form of the program created by using the Borland C++ Builder 6.

Multímetro interfaceado de baixo custo para aquisição de dados

A digital multimeter (~U$ 240.00 on the national market) connected to a microcomputer by a RS-232 serial interface is proposed for data acquisition in equipment with analog output. Data are measured at the rate of 2 points per second and stored in text files by the software that accompanies the device, running in a Windows environment. The performance of the multimeter was verified by monitoring the transient signals generated in flow injection systems associated with fluorimetric, spectrophotometric and flame photometric detection. In addition, the performance of the proposed device was similar to that attained by employing an interface card with a 12-bit analog-to-digital converter for acquisition of the signals generated by a capillary electrophoresis equipment with oscillometric detection.

Identificação de substâncias em análise toxicológica sistemática utilizando um sistema informatizado para cálculo de parâmetros cromatográficos e busca em bases de dados

In spite of the availability of large databases of chromatographic data on several standardized systems, one major task in systematic toxicological analysis remains, namely how to handle the experimental data and retrieve data from the large available databases in a meaningful and productive way. To achieve this purpose, our group proposed an Internet-based tool using previously published STA databases, which interlaboratorial reproducibility tests have already evaluated. The developed software has the capability to calculate corrected chromatographic parameters, after the input of data obtained with standard mixtures of calibrators, and search the databases, currently incorporating TLC, color reactions, GC and HPLC data. At the end of the process, a list with candidate substances and their similarity indexes is presented.

JNK regulates dendrite and spine architecture in the central nervous system influencing spatial learning and motor tasks

JNK1 is a MAP-kinase that has proven a significant player in the central nervous system. It regulates brain development and the maintenance of dendrites and axons. Several novel phosphorylation targets of JNK1 were identified in a screen performed in the Coffey lab. These proteins were mainly involved in the regulation of neuronal cytoskeleton, influencing the dynamics and stability of microtubules and actin. These structural proteins form the dynamic backbone for the elaborate architecture of the dendritic tree of a neuron. The initiation and branching of the dendrites requires a dynamic interplay between the cytoskeletal building blocks. Both microtubules and actin are decorated by associated proteins which regulate their dynamics. The dendrite-specific, high molecular weight microtubule associated protein 2 (MAP2) is an abundant protein in the brain, the binding of which stabilizes microtubules and influences their bundling. Its expression in non-neuronal cells induces the formation of neurite-like processes from the cell body, and its function is highly regulated by phosphorylation. JNK1 was shown to phosphorylate the proline-rich domain of MAP2 in vivo in a previous study performed in the group. Here we verify three threonine residues (T1619, T1622 and T1625) as JNK1 targets, the phosphorylation of which increases the binding of MAP2 to microtubules. This binding stabilizes the microtubules and increases process formation in non-neuronal cells. Phosphorylation-site mutants were engineered in the lab. The non-phosphorylatable mutant of MAP2 (MAP2- T1619A, T1622A, T1625A) in these residues fails to bind microtubules, while the pseudo-phosphorylated form, MAP2- T1619D, T1622D, Thr1625D, efficiently binds and induces process formation even without the presence of active JNK1. Ectopic expression of the MAP2- T1619D, T1622D, Thr1625D in vivo in mouse brain led to a striking increase in the branching of cortical layer 2/3 (L2/3) pyramidal neurons, compared to MAP2-WT. The dendritic complexity defines the receptive field of a neuron and dictates the output to the postsynaptic cells. Previous studies in the group indicated altered dendrite architecture of the pyramidal neurons in the Jnk1-/- mouse motor cortex. Here, we used Lucifer Yellow loading and Sholl analysis of neurons in order to study the dendritic branching in more detail. We report a striking, opposing effect in the absence of Jnk1 in the cortical layers 2/3 and 5 of the primary motor cortex. The basal dendrites of pyramidal neurons close to the pial surface at L2/3 show a reduced complexity. In contrast, the L5 neurons, which receive massive input from the L2/3 neurons, show greatly increased branching. Another novel substrate identified for JNK1 was MARCKSL1, a protein that regulates actin dynamics. It is highly expressed in neurons, but also in various cancer tissues. Three phosphorylation target residues for JNK1 were identified, and it was demonstrated that their phosphorylation reduces actin turnover and retards migration of these cells. Actin is the main cytoskeletal component in dendritic spines, the site of most excitatory synapses in pyramidal neurons. The density and gross morphology of the Lucifer Yellow filled dendrites were characterized and we show reduced density and altered morphology of spines in the motor cortex and in the hippocampal area CA3. The dynamic dendritic spines are widely considered to function as the cellular correlate during learning. We used a Morris water maze to test spatial memory. Here, the wild-type mice outperformed the knock-out mice during the acquisition phase of the experiment indicating impaired special memory. The L5 pyramidal neurons of the motor cortex project to the spinal cord and regulate the movement of distinct muscle groups. Thus the altered dendrite morphology in the motor cortex was expected to have an effect on the input-output balance in the signaling from the cortex to the lower motor circuits. A battery of behavioral tests were conducted for the wild-type and Jnk1-/- mice, and the knock-outs performed poorly compared to wild-type mice in tests assessing balance and fine motor movements. This study expands our knowledge of JNK1 as an important regulator of the dendritic fields of neurons and their manifestations in behavior.

Building-up influence: post-war industrialization in the State of Minas Gerais, Brazil

This paper examines the post-War industrialization process in the Brazilian State of Minas Gerais, focusing on one of its desirable outcomes, namely the capacity to generate growth through the impact of strong input-output linkages. This process is placed into historical perspective considering the ideas that permeate the economic development debate throughout the period of analysis. Changes in the regional economic structure are assessed through the use of three input-output tables for the years of 1953, 1980 and 1995. By adopting the fields of influence methodology as the analytical core, it is shown that the efforts towards the creation of a more integrated regional economy have generated stronger influence of the targeted sectors (metal products, transportation equipment, chemical, and services). However, structural changes also contributed to strengthen leakage in the system originated in traditional economic activities.

The Transformation Problem : an Aleternative Solution with an Identical Aggregate Profit Rate in the Labor value and the Monetary Space.

The aim of this paper is to demonstrate that, even if Marx's solution to the transformation problem can be modified, his basic conclusions remain valid. the proposed alternative solution which is presented hare is based on the constraint of a common general profit rate in both spaces and a money wage level which will be determined simultaneously with prices.

The Wage Rate and the Profit Rate in the Price of Production Equation: a New Solution to an Old Problem

The aim of this paper is to demonstrate that, even if Marx's solution to the transformation problem can be modified, his basic concusions remain valid.

Nearly Serial Sharing Methods

A group of agents participate in a cooperative enterprise producing a single good. Each participant contributes a particular type of input; output is nondecreasing in these contributions. How should it be shared? We analyze the implications of the axiom of Group Monotonicity: if a group of agents simultaneously decrease their input contributions, not all of them should receive a higher share of output. We show that in combination with other more familiar axioms, this condition pins down a very small class of methods, which we dub nearly serial.

The Transmission of Monetary Policy in a Multi-Sector Economy

This paper constructs and estimates a sticky-price, Dynamic Stochastic General Equilibrium model with heterogenous production sectors. Sectors differ in price stickiness, capital-adjustment costs and production technology, and use output from each other as material and investment inputs following an Input-Output Matrix and Capital Flow Table that represent the U.S. economy. By relaxing the standard assumption of symmetry, this model allows different sectoral dynamics in response to monetary policy shocks. The model is estimated by Simulated Method of Moments using sectoral and aggregate U.S. time series. Results indicate 1) substantial heterogeneity in price stickiness across sectors, with quantitatively larger differences between services and goods than previously found in micro studies that focus on final goods alone, 2) a strong sensitivity to monetary policy shocks on the part of construction and durable manufacturing, and 3) similar quantitative predictions at the aggregate level by the multi-sector model and a standard model that assumes symmetry across sectors.

The Transformation Problem : an Aleternative Solution with an Identical Aggregate Profit Rate in the Labor value and the Monetary Space.

The aim of this paper is to demonstrate that, even if Marx's solution to the transformation problem can be modified, his basic conclusions remain valid. the proposed alternative solution which is presented hare is based on the constraint of a common general profit rate in both spaces and a money wage level which will be determined simultaneously with prices.