998 resultados para Martin, Thomas Ignace, 1783-1834.


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Documents and books pertaining to Julius Streicher

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The built environment is a major contributor to the world’s carbon dioxide emissions, with a considerable amount of energy being consumed in buildings due to heating, ventilation and air-conditioning, space illumination, use of electrical appliances, etc., to facilitate various anthropogenic activities. The development of sustainable buildings seeks to ameliorate this situation mainly by reducing energy consumption. Sustainable building design, however, is a complicated process involving a large number of design variables, each with a range of feasible values. There are also multiple, often conflicting, objectives involved such as the life cycle costs and occupant satisfaction. One approach to dealing with this is through the use of optimization models. In this paper, a new multi-objective optimization model is developed for sustainable building design by considering the design objectives of cost and energy consumption minimization and occupant comfort level maximization. In a case study demonstration, it is shown that the model can derive a set of suitable design solutions in terms of life cycle cost, energy consumption and indoor environmental quality so as to help the client and design team gain a better understanding of the design space and trade-off patterns between different design objectives. The model can very useful in the conceptual design stages to determine appropriate operational settings to achieve the optimal building performance in terms of minimizing energy consumption and maximizing occupant comfort level.

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Banana bunchy top virus (BBTV; family Nanoviridae, genus Babuvirus) is a multi-component single-stranded DNA virus, which infects banana plants in many regions of the world, often resulting in large-scale crop losses. Weanalyzed 171 banana leaf samples from fourteen countries and recovered, cloned, and sequenced 855 complete BBTV components including ninety-four full genomes. Importantly, full genomes were determined from eight countries, where previously no full genomes were available (Samoa, Burundi, Republic of Congo, Democratic Republic of Congo, Egypt, Indonesia, the Philippines, and the USA [HI]). Accounting for recombination and genome component reassortment, we examined the geographic structuring of global BBTV populations to reveal that BBTV likely originated in Southeast Asia, that the current global hotspots of BBTV diversity are Southeast Asia/Far East and India, and that BBTV populations circulating elsewhere in the world have all potentially originated from infrequent introductions. Most importantly, we find that rather than the current global BBTV distribution being due to increases in human-mediated movements of bananas over the past few decades, it is more consistent with a pattern of infrequent introductions of the virus to different parts of the world over the past 1,000 years.

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Developing major infrastructure and construction (MIC) projects is complicated, since it involves multifaceted policy issues. As a result, appropriate participatory mechanisms have been increasingly employed to improve the legitimacy of the project decision process. Yet it cannot always guarantee a mutually acceptable solution since the expectations and requirements of multiple stakeholders involved can be diverse and even conflicting. Overcoming this necessitates a thorough identification and careful analysis of the expectations of various stakeholder groups in MIC projects. On the other hand, though most project stakeholder concerns are consistent across the globe, contextual differences may lead to diverse priority levels being attached to these factors. This research, therefore, aimed to examine the perceptual differences between paired stakeholder groups from mainland China mega-cities and Hong Kong in rating their concerns over MIC projects. The research findings are expected to benefit both the Central Government of China and the Government of Hong Kong SAR for coping better with the rapid expansion of MIC projects in the territory and the increasing expectations of social equality, and therefore achieving the much desired harmonious development of the community.

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The purpose of this study is to examine the reception of Matthew 5 in Martin Luther s sermons; in other words to investigate how Luther interprets and applies Jesus teaching of the better righteousness and the law in Mt 5. The study applies the reception-historical approach and contributes to the history of effects and the history of interpretation in New Testament exegesis. The study shows that Luther understands the better righteousness of Mt 5 as good works and fulfillment of the law. Luther s interpretation coheres with the intention of the Evangelist, even if Luther s overall concept of righteousness is foreign to Matthew. In Luther s view righteousness is twofold: The greater righteousness of Mt 5 is the second and the actual righteousness (iustitia activa), which follows the first and the foreign righteousness (iustitia passiva). The first righteousness (faith) is for Luther the work of God, while the second righteousness (good works) is co-operation between a Christian and God. In this co-operation the law, as it is taught by Jesus, is not the opposite of the gospel, but the gospel itself in the sense of Christ as an example . The task of the law is to show the dependence of a Christian on God and to help one to love and to serve one s neighbour (brothers as well as enemies) properly. The study underlines a feature in Luther s thinking that has received little attention in Lutheran theology: Luther insists on preaching the law to Christians. In his view Mt 5 is directed to all Christians and particularly to pastors, for whom Jesus here gives an example of how to preach the law. Luther believes similarly to Matthew that Jesus reveals the real meaning of Mosaic Law and confirms its validity for Christians in Mt 5. Like Matthew, Luther insists on the practicability of the commandments of Mt 5 in his view Christians fulfil the law also with joy yet his interpretation of Mt 5 attenuates the radical nature of its commandments. Luther s reception of the individual pericopes of Mt 5 is considerably generative and occasionally contradictory, which is explained by the following factors, among others: Luther receives many ideas from tradition and reads them and his own theological concepts into Matthew s Gospel. He interprets Mt 5 through his understanding of some Old Testament passages as well as Paul. Most of all, Luther s reception of Mt 5 is shaped by his own experience as a preacher, by his relation to his religious enemies, rulers and to the congregation of Wittenberg. Here Luther shares with Matthew the experience of being opposed and concern about the upright living of the believers, which in both cases also explains the polemical tone of the paraenesis.

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BACKGROUND Polygenic risk scores comprising established susceptibility variants have shown to be informative classifiers for several complex diseases including prostate cancer. For prostate cancer it is unknown if inclusion of genetic markers that have so far not been associated with prostate cancer risk at a genome-wide significant level will improve disease prediction. METHODS We built polygenic risk scores in a large training set comprising over 25,000 individuals. Initially 65 established prostate cancer susceptibility variants were selected. After LD pruning additional variants were prioritized based on their association with prostate cancer. Six-fold cross validation was performed to assess genetic risk scores and optimize the number of additional variants to be included. The final model was evaluated in an independent study population including 1,370 cases and 1,239 controls. RESULTS The polygenic risk score with 65 established susceptibility variants provided an area under the curve (AUC) of 0.67. Adding an additional 68 novel variants significantly increased the AUC to 0.68 (P = 0.0012) and the net reclassification index with 0.21 (P = 8.5E-08). All novel variants were located in genomic regions established as associated with prostate cancer risk. CONCLUSIONS Inclusion of additional genetic variants from established prostate cancer susceptibility regions improves disease prediction. Prostate 75:1467–1474, 2015. © 2015 Wiley Periodicals, Inc.

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Homozygosity has long been associated with rare, often devastating, Mendelian disorders1, and Darwin was one of the first to recognize that inbreeding reduces evolutionary fitness2. However, the effect of the more distant parental relatedness that is common in modern human populations is less well understood. Genomic data now allow us to investigate the effects of homozygosity on traits of public health importance by observing contiguous homozygous segments (runs of homozygosity), which are inferred to be homozygous along their complete length. Given the low levels of genome-wide homozygosity prevalent in most human populations, information is required on very large numbers of people to provide sufficient power3, 4. Here we use runs of homozygosity to study 16 health-related quantitative traits in 354,224 individuals from 102 cohorts, and find statistically significant associations between summed runs of homozygosity and four complex traits: height, forced expiratory lung volume in one second, general cognitive ability and educational attainment (P < 1 × 10−300, 2.1 × 10−6, 2.5 × 10−10 and 1.8 × 10−10, respectively). In each case, increased homozygosity was associated with decreased trait value, equivalent to the offspring of first cousins being 1.2 cm shorter and having 10 months’ less education. Similar effect sizes were found across four continental groups and populations with different degrees of genome-wide homozygosity, providing evidence that homozygosity, rather than confounding, directly contributes to phenotypic variance. Contrary to earlier reports in substantially smaller samples5, 6, no evidence was seen of an influence of genome-wide homozygosity on blood pressure and low density lipoprotein cholesterol, or ten other cardio-metabolic traits. Since directional dominance is predicted for traits under directional evolutionary selection7, this study provides evidence that increased stature and cognitive function have been positively selected in human evolution, whereas many important risk factors for late-onset complex diseases may not have been.

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Accurate characterization and reporting of organic photovoltaic (OPV) device performance remains one of the important challenges in the field. The large spread among the efficiencies of devices with the same structure reported by different groups is significantly caused by different procedures and equipment used during testing. The presented article addresses this issue by offering a new method of device testing using “suitcase sample” approach combined with outdoor testing that limits the diversity of the equipment, and a strict measurement protocol. A round robin outdoor characterization of roll-to-roll coated OPV cells and modules conducted among 46 laboratories worldwide is presented, where the samples and the testing equipment were integrated in a compact suitcase that served both as a sample transportation tool and as a holder and test equipment during testing. In addition, an internet based coordination was used via plasticphotovoltaics.org that allowed fast and efficient communication among participants and provided a controlled reporting format for the results that eased the analysis of the data. The reported deviations among the laboratories were limited to 5% when compared to the Si reference device integrated in the suitcase and were up to 8% when calculated using the local irradiance data. Therefore, this method offers a fast, cheap and efficient tool for sample sharing and testing that allows conducting outdoor measurements of OPV devices in a reproducible manner.

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A detailed study is presented of the expected performance of the ATLAS detector. The reconstruction of tracks, leptons, photons, missing energy and jets is investigated, together with the performance of b-tagging and the trigger. The physics potential for a variety of interesting physics processes, within the Standard Model and beyond, is examined. The study comprises a series of notes based on simulations of the detector and physics processes, with particular emphasis given to the data expected from the first years of operation of the LHC at CERN.

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Pro gradu -tutkielmani tehtävänä on selvittää näkökulmia melankoliaterapiaan Martti Lutherin lohdutuskirjeissä. Lähteinä on ollut neljä lohdutuskirjettä sekä yksi kirje, joka muistuttaa sisällöltään lohdutuskirjettä. Metodina on ollut kirjeiden tyylillis-retorinen analyysi. Aihe on kiinnostava, koska Lutherin kirjeiden ja retoriikan tutkimus on ollut vähäistä verrattuna häntä koskevaan laajaan kansainväliseen tutkimukseen. Työn lähtökohtana on ollut, että yksi kirjallisuuden tärkeimmistä tehtävistä 1500-luvulla oli erilaisten melankolisten sairauksien parantaminen. Kirjallisuuden avulla voitiin torjua hengenvaarallisia melankolisia affekteja kuten epätoivoa, pelkoa, surua ja apatiaa. Lutherin lohdutuskirjeet soveltuvat hyvin melankoliaterapian tutkimiseen, koska ne on kirjoitettu lohtua tarvitseville ihmisille. Työn tutkimuskysymykset ovat: Mitä melankolian hoitokeinoja Luther mainitsee? Missä määrin Lutherin melankoliaterapia on sopusoinnussa 1500-luvulla vallinneiden hoitokäsitysten kanssa? Miten Luther hyödyntää retoriikan ja huumorin keinoja melankoliaterapiassaan? Työn teoriaosassa selvitetään 1500-luvun ihmiskäsitystä sekä teologisesta että lääketieteellisestä näkökulmasta ja esitellään ajalle tyypillisiä humoraaliopin mukaisia melankolian hoitokeinoja. Selvitetään myös retoriikan ja melankoliaterapian suhdetta toisiinsa. Analyysiosassa pääpaino on Lutherin käyttämissä retorisissa keinoissa, mutta siinä hyödynnetään myös teoriaosan havaintoja. Tutkielmassa kirjallisuustieteellinen ja teologinen näkökulma tukevat toisiaan. Kirjallisuustieteellisestä näkökulmasta lohdutuskirjeet on tutkittavissa retoriikan tarjoamien käsitteiden avulla, koska ne on kirjoitettu aikana, jolloin retoriikka oli tärkeä yliopistollinen oppiaine. Tutkielma huomioi myös aiheen teologisen näkökulman, koska ajan kieli on uskonnollisesti värittynyttä ja koska Lutherin melankoliaterapiaan kuuluu vahva hengellinen ulottuvuus. Ihmisen kyky lohduttaa rinnastuu Lutherilla Jumalan kykyyn lohduttaa ihmistä Raamatun sanan kautta. Lutherille Jumala on reetori, jonka työväline on Raamatun pyhä sana. Puhutulla ja kirjoitetulla sanalla on Lutherin melankoliaterapiassa erityisen keskeinen merkitys. Tutkielmani osoittaa, että sekä Lutherin käyttämät retoriset keinot että hänen melankoliaterapiansa ovat suuressa määrin sopusoinnussa 1500-luvun retoriikan ja lääketieteen oppien kanssa. Luther käyttää melankoliaterapiassaan laajasti apuna erilaisia retorisia keinoja kuten toistoa, variaatiota, metaforaa ja esimerkkikertomuksia. Lutherin mainitsemat hoitokeinot kuten esimerkiksi metsästys, ratsastus, syöminen ja juominen, pelien pelaaminen, leikinlasku ja ystävien kanssa seurustelu ovat sopusoinnussa ajan hoitokäsitysten kanssa. Kirjeissä esiintyy myös lääketieteellisestä ja uskonnollisesta näkökulmasta katsottuna kyseenalaisia hoitokeinoja kuten tyhjänpäiväisten juttujen kertominen ja paholaisen kiroileminen. Nämä neuvot ylittävät ajan melankoliaterapiaan kuuluvan kohtuullisuuden säännön, ja ne on ymmärrettävä niiden teologisesta merkityksestä käsin. Lutherille kohtuullisuuden säännön rikkominen on toisinaan sallittua, kun on kysymys vaikeasta paholaisen aiheuttamasta melankoliasta. Kristillinen usko näyttää Lutherille tarjoavan vapauden käyttää tiettyjä hoitokeinoja, joita vielä keskiajalla ei olisi hyväksytty. Toisinaan Luther näkee kirjeen vastaanottajaa kohdanneen vaikeuden Jumalan eikä paholaisen aikaansaannoksena. Tällaisissa tapauksissa melankolia nähdään Jumalan työnä ihmisessä, joka mahdollistaa hengellisen kääntymisen Jumalan, kaiken lohdutuksen Isän puoleen.

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Käsilläolevan tutkielman aiheena on esineellistymisen käsite. Sitä tarkastellaan yhtäältä sellaisena kuten se esitetään Georg Lukácsin (1885-1971) teoksessa Historia ja luokkatietoisuus (1923), toisaalta kuten sitä koskeva teoria on luettavissa esiin Martin Heideggerin (1889-1976) läpimurtoteoksesta Oleminen ja aika (1927). Molemmat ajattelijat pyrkivät teoksissaan rakentamaan kokonaisvaltaista tulkintaa länsimaisen ajattelun ja toiminnan taipumuksesta tulkita todellisuus esineellisenä (dinglich), so. eletystä elämästä ja toiminnasta irrallisena olioiden (Dinge) maailmana. Sekä Lukács että Heidegger pyrkivät osoittamaan, että esineellistyneen todellisuuden ontologisena perustana toimii inhimillisen praktisen toiminnan kenttä, josta käsin esineellistävät ja objektivoivat suhtautumistavat todellisuuteen voivat vasta jälkikäteisesti syntyä. Molemmille ajattelijoille esineellisyyden muodostuminen ontologiaa hallitsevaksi tulkinnaksi todellisuuden luonteesta edellyttää myös tietynlaisia sosiaalisen olemisen rakenteita. Tutkielmassa tehdään vertailevaa käsiteanalyysia Lukácsin ja Heideggerin teoreettisten diskurssien välillä. Tavoitteena on rakentaa mahdollisuutta lukea mainittuja filosofeja saman, modernille olemassaololle keskeisen ontologisen sekä eksistentiaalisen ongelman tarkastelijoina. Toisaalta vertaileva lähestymistapa pyrkii myös tuomaan esiin olennaisia ja perustavia eroja Lukácsin marxilaisen ja Heideggerin fundamentaaliontologisen orientaation välillä. Tutkielmassa pyritäänkin osoittamaan, että Heideggerin fundamentaaliontologia ei tarkastele kauppatavaran rakennetta eikä sosiaalisen vaihdon prosesseja marxilaisesta näkökulmasta riittävällä tavalla, kun taas Lukácsin teoreettinen projekti tulee edellyttäneeksi tuottavaan subjektiviteettiin pohjautuvan ontologisen perusasenteen. Tämä ontologinen positio voidaan puolestaan kritisoida hedelmällisesti heideggerilaisesta näkökulmasta. Viime kädessä tutkielma pyrkii avaamaan esineellistymisteorioiden vertailun kautta kysymyksen länsimarxilaisen materialistisen dialektiikan ja Heideggerin fenomenologisen ontologian välisestä suhteesta.

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We use the Thomas-Fermi method to examine the thermodynamics of particles obeying Haldane exclusion statistics. Specifically, we study Calogero-Sutherland particles placed in a given external potential in one dimension. For the case of a simple harmonic potential (constant density of states), we obtain the exact one-particle spatial density and a {\it closed} form for the equation of state at finite temperature, which are both new results. We then solve the problem of particles in a $x^{2/3} ~$ potential (linear density of states) and show that Bose-Einstein condensation does not occur for any statistics other than bosons.