Synthesis and spectroscopic characterization of new metal(II) complexes with methionine sulfoxide

Methionine sulfoxide complexes of iron(II) and copper(II) were synthesized and characterized by chemical and spectroscopic techniques. Elemental and atomic absorption analyses fit the compositions K2[Fe(metSO) 2]SO4 · H2O and [Cu(metSO)2] · H2O. Electronic absorption spectra of the complexes are typical of octahedral geometries. Infrared spectroscopy suggests coordination of the ligand to the metal through the carboxylate and sulfoxide groups. An EPR spectrum of the Cu(II) complex indicates tetragonal distortion of its octahedral symmetry. 57Fe Mössbauer parameters are also consistent with octahedral stereochemistry for the iron(II) complex. The complexes are very soluble in water.

Chiral symmetry breaking with a confining propagator and dynamically massive gluons

Chiral symmetry breaking in QCD is studied introducing a confining effective propagator, as proposed recently by Cornwall, and considering the effect of dynamically massive gluons. The effective confining propagator has the form 1/(k2 +m2)2 and we study the bifurcation equation finding limits on the parameter m below which a satisfactory fermion mass solution is generated. Since the coupling constant and gluon propagator are damped in the infrared, due to the presence of a dynamical gluon mass, the major part of the chiral breaking is only due to the confining propagator and related to the low momentum region of the gap equation. We study the asymptotic behavior of the gap equation containing this confinement effect and massive gluon exchange, and find that the symmetry breaking can be approximated by an effective four-fermion interaction generated by the confining propagator. We compute some QCD chiral parameters as a function of m, finding values compatible with the experimental data. We find a simple approximate relation between the fermion condensate and dynamical mass for a given representation as a function of the parameters appearing in the effective confining propagator. © Copyright owned by the author(s) under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike Licence.

Batalin-Fradkin-Vilkovisky quantization of the generalized scalar electrodynamics

This work comprises a study upon the quantization and the renormalizability of the generalized electrodynamics of spinless charged particles (mesons), namely, the generalized scalar electrodynamics (GSQED4). The theory is quantized in the covariant framework of the Batalin-Fradkin-Vilkovisky method. Thereafter, the complete Green's functions are obtained through functional methods and a proper discussion on the theory's renormalizability is also given. Next, we present the computation and further discussion on the radiative correction at α order; and, as it turns out, an unexpected mP-dependent divergence on the mesonic sector of the theory is found. Furthermore, in order to show the effectiveness of the renormalization procedure on the present theory, we also give a diagrammatic discussion on the photon self-energy at α2 order, where we observe contributions from the meson self-energy function. Afterwards, we present the expressions of the counterterms and effective coupling of the theory, obtaining from the latter an energy range where the theory is defined by m2≤k2

Dynamics of bone healing after osteotomy with piezosurgery or conventional drilling - histomorphometrical, immunohistochemical, and molecular analysis

Background: Piezosurgery is an osteotomy system used in medical and dental surgery. Many studies have proven clinical advantages of piezosurgery in terms of quality of cut, maneuverability, ease of use, and safety. However, few investigations have tested its superiority over the traditional osteotomy systems in terms of dynamics of bone healing. Therefore, the aim of this study was to evaluate the dynamics of bone healing after osteotomies with piezosurgery and to compare them with those associated to traditional bone drilling.Methods: One hundred and ten rats were divided into two groups with 55 animals each. The animals were anesthetized and the tibiae were surgically exposed to create defects 2 mm in diameter by using piezosurgery (Piezo group) and conventional drilling (Drill group). Animals were sacrificed at 3, 7, 14, 30 and 60 days post-surgery. Bone samples were collected and processed for histological, histomorphometrical, immunohistochemical, and molecular analysis. The histological analysis was performed at all time points (n = 8) whereas the histomorphometrical analysis was performed at 7, 14, 30 and 60 days post-surgery (n = 8). The immunolabeling was performed to detect Vascular Endothelial Growth Factor (VEGF), Caspase-3 (CAS-3), Osteoprotegerin (OPG), Receptor Activator of Nuclear Factor kappa-B Ligand (RANKL), and Osteocalcin (OC) at 3, 7, and 14 days (n = 3). For the molecular analysis, animals were sacrificed at 3, 7 and 14 days, total RNA was collected, and quantification of the expression of 21 genes related to BMP signaling, Wnt signaling, inflammation, osteogenenic and apoptotic pathways was performed by qRT-PCR (n = 5).Results: Histologically and histomorphometrically, bone healing was similar in both groups with the exception of a slightly higher amount of newly formed bone observed at 30 days after piezosurgery (p < 0.05). Immunohistochemical and qRT-PCR analyses didn't detect significant differences in expression of all the proteins and most of the genes tested.Conclusions: Based on the results of our study we conclude that in a rat tibial bone defect model the bone healing dynamics after piezosurgery are comparable to those observed with conventional drilling. © 2013 Esteves et al.; licensee BioMed Central Ltd.

Influência das proteínas morfogenéticas ósseas adsorvidas à hidroxiapatita e aglutinantes do colágeno bovino na consolidação da fratura do rádio em coelhos

Pós-graduação em Medicina Veterinária - FMVZ

Detecção e ação antimicrobiana e antiendotóxica do extrato glicólico de gengibre utilizado como substância química auxiliar durante o retratamento endodôntico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise, por MEV, da efetividade de soluções irrigadoras e substâncias químicas auxiliares na limpeza de canais radiculares e estudo complementar da interferência desta limpeza na penetração do cimento obturador nos túbulos dentinários

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação in vitro da ação de substâncias químicas auxiliares e medicações intracanais sobre Escherichia coli e sua endotoxina em canais radiculares

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Níveis de adubação potássica na cultura da figueira

Pós-graduação em Agronomia (Horticultura) - FCA

Ação de biomateriais e laser de baixa intensidade na reparação tecidual óssea: estudo histológico em ratos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Interrelações da produtividade de cana-de-açúcar com atributos químicos de um argissolo vermelho eutrófico paulista

Pós-graduação em Agronomia - FEIS

Variabilidade espacial da produtividade de forragem do milho safrinha em função de atributos químicos do solo

Pós-graduação em Agronomia - FEIS

Avaliação da presença das proteínas VEGF, BMP2 e CBFA1 no enxerto ósseo autógeno: análise histométrica e imunoistoquímica em calotas de ratos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Citotoxicidade, genotoxicidade e expressão gênica em células da polpa dental humana sensibilizadas por cimentos endodônticos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Produtividade e qualidade de frutos de melão pele de sapo em função de diferente níveis de irrigação e adubações nitrogenada e potássica

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)