INTERPLAY OF CAF2 SUBSTRATE ROUGHENING AND FILM DEPOSITION RATE ON RADIATIVE SCATTERING OF SURFACE-PLASMON POLARITONS FROM AG FILMS

The radiative decay of surface plasmon polaritons has been investigated in an attempt to characterize the surface roughness of Ag films prepared under different conditions. The polaritons were excited by the method of attenuated total reflection of light. The films were deposited on the face of a 60-degrees BK-7 glass prism at a rate that was deliberately fixed in two different ranges (centred on 0.1 and 10 nm s-1) and in some cases a CaF2 underlayer was used to roughen the film surfaces. The intensity of the scattered light emitted from the opposite face of the films was measured as a function of direction for each using the same sensitivity scale and was correlated with the preparation of the film. It was found that on nominally smooth substrates fast-deposited thinner films give out more light and are deduced to have greater short wavelength (300-600 nm) roughness amplitude. There is also evidence for long wavelenth (7 mum) periodic roughness due to the prism substrate itself. On CaF2 roughened surfaces the light output from the films is further increased and the peak intensity is backward directed with respect to the exciting laser beam direction. Here roughness on a lateral scale of 350 nm is responsible. Also, elastic scattering of surface plasmon polaritons at grain boundaries reduces the light output from fast deposited, small grain, films on CaF2 roughened surfaces. Overall, a consistent picture of roughness induced radiative polariton decay emerges for all cases studied.

Preferred Reporting Items for a Systematic Review and Meta-analysis of Individual Participant Data The PRISMA-IPD Statement

IMPORTANCE Systematic reviews and meta-analyses of individual participant data (IPD) aim to collect, check, and reanalyze individual-level data from all studies addressing a particular research question and are therefore considered a gold standard approach to evidence synthesis. They are likely to be used with increasing frequency as current initiatives to share clinical trial data gain momentum and may be particularly important in reviewing controversial therapeutic areas.

OBJECTIVE To develop PRISMA-IPD as a stand-alone extension to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) Statement, tailored to the specific requirements of reporting systematic reviews and meta-analyses of IPD. Although developed primarily for reviews of randomized trials, many items will apply in other contexts, including reviews of diagnosis and prognosis.

DESIGN Development of PRISMA-IPD followed the EQUATOR Network framework guidance and used the existing standard PRISMA Statement as a starting point to draft additional relevant material. A web-based survey informed discussion at an international workshop that included researchers, clinicians, methodologists experienced in conducting systematic reviews and meta-analyses of IPD, and journal editors. The statement was drafted and iterative refinements were made by the project, advisory, and development groups. The PRISMA-IPD Development Group reached agreement on the PRISMA-IPD checklist and flow diagram by consensus.

FINDINGS Compared with standard PRISMA, the PRISMA-IPD checklist includes 3 new items that address (1) methods of checking the integrity of the IPD (such as pattern of randomization, data consistency, baseline imbalance, and missing data), (2) reporting any important issues that emerge, and (3) exploring variation (such as whether certain types of individual benefit more from the intervention than others). A further additional item was created by reorganization of standard PRISMA items relating to interpreting results. Wording was modified in 23 items to reflect the IPD approach.

CONCLUSIONS AND RELEVANCE PRISMA-IPD provides guidelines for reporting systematic reviews and meta-analyses of IPD.

Relationships Between Deprivation and the Self-reported Health of Older People in Northern Ireland

Objectives: There are few studies on relationships between deprivation and the self-reported health of people aged over 64 years, and no studies fully representative of Northern Ireland’s older population. This paper addresses this gap. Methods: Deprivation of older people as reported in the 2001 and 2011 Censuses and the relationship with self-reported health are analyzed over a ten-year span using multilevel modeling. The data are from the Northern Ireland Longitudinal Study (NILS) linked to 2001-11 Census returns. Deprivation measures include housing tenure, property-value, access to a car, educational, employment and area-level income-deprivation. Results: Older people suffering deprivation face a significant health disadvantage over a ten-year time span. Discussion: This health disadvantage is stronger in men than in women, likely due to conservative gender roles prevalent among Northern Ireland’s older population, leading to psychological distress among deprived men. The analysis found strongly significant area-level effects, aggravating the health impact of deprivation.

La aportación de Tromlitz: estudio comparativo y aplicaciones prácticas

Os escritos de Johann Georg Tromlitz (1725-1805) são uma fonte inestimável de informação e inspiração para o actual intérprete e estudioso. Entre estes destaco o Ausfühlicher und gründlicher Unterricht die Flöte zu spielen [Método minucioso e detalhado para tocar flauta], 1791, claramente inspirado no tratado de Quantz de 1752, mas reflectindo a necessidade que o autor teve de o actualizar. Este tratado de Tromlitz foi projectado para que o leitor se pudesse tornar um Virtuoso sem recorrer a um professor, de modo que as informações são apresentadas de um modo muito detalhado em todos os aspectos. Infelizmente, este tratado não é muito conhecido entre o público de língua espanhola, devido à falta de traduções, assim que um dos principais objectivos desta tese foi oferecer uma primeira versão para o público de língua espanhola. Para o enquadrar no contexto europeu, fez-se uma comparação com os métodos de flauta mais importantes da última década do século, tendo em conta vários aspectos fundamentais relacionados com a interpretação: som, respiração, articulação e ornamentação. A partir das concluções de este trabalho comparativo foram geradas as directrices que guiaram a interpretação do autor de um repertorio representantivo deste período histórico, disponibilizando-se num CD a gravação dos excertos que serviram de exemplo para aplicação dos resultados da investigação.

Contribución al estudio del patrimonio de Cacela: cartografía, arquitectura y paisaje en el contexto del algarve oriental en Portugal

El presente artículo estudia la cartografía de Cacela en el sur de Portugal con el propósito de interpretar su transformación a través del tiempo, considerando la arquitectura, el urbanismo y el paisaje de forma integrada. La lectura de esa transformación se lleva de la mano de las principales cartas de Cacela que coinciden con el inicio del siglo XVII, la aproximación al final del Antiguo Régimen y la transición del siglo XIX al XX, asociando cada uno de estos tiempos a un modo particular de representación. La interpretación de las diferentes cartas está organizada, en términos me- todológicos, a partir del recurso a fuentes escritas de la época, culminando con la elaboración de un dibujo final que contiene la representación del espacio edificado y del paisaje de Cacela a mediados del siglo pasado. Este trabajo se inscribe en una investigación más amplia sobre las aglomeraciones urbanas de pequeña dimensión en las diver- sas subunidades geográficas del sur de Portugal, comprendiendo el paisaje, la morfología urbana y el levantamiento integral de todo el núcleo edificado.

Spectroscopic techniques for characterizing portuguese glazed ceramics:a contribution to the study of ancient faiences of Coimbra

Tese de doutoramento, Física, Universidade de Lisboa, Faculdade de Ciências, 2013

Potencialidades y limitaciones de los entornos virtuales colaborativos y las herramientas web 2.0 en la promoción del activismo sobre cuestiones ambientales en estudiantes de básica secundaria

Esta comunicación presenta algunos resultados preliminares de un trabajo de doctorado que tiene como objetivo Identificar cuáles son las potencialidades y limitaciones de los entornos virtuales colaborativos y las herramientas web 2.0 en la promoción del activismo sobre cuestiones ambientales en estudiantes de básica secundaria, se hace una descripción de la metodología que se enmarca dentro del paradigma de la complejidad y la evolución, la investigación acción y el análisis documental, es de carácter cualitativo y cuantitativo; al final se presenta un análisis preliminar de los resultados obtenidos con los blogs construidos por los estudiantes.

O INSTITUTO DE ENGENHARIA NUCLEAR E O REATOR ARGONAUTA Uma breve história

O documento conta a história de criação e fundação do Instituto de Engenharia Nuclear-IEN.

Modelling group decision simulation through argumentation

Group decision making plays an important role in today’s organisations. The impact of decision making is so high and complex, that rarely the decision making process is made individually. In Group Decision Argumentation, there is a set of participants, with different profiles and expertise levels, that exchange ideas or engage in a process of argumentation and counter-argumentation, negotiate, cooperate, collaborate or even discuss techniques and/or methodologies for problem solving. In this paper, it is proposed a Multi-Agent simulator for the behaviour representation of group members in a decision making process. Agents behave depending on rational and emotional intelligence and use persuasive argumentation to convince and make alternative choices.

The isolation and characterization of cytochrome c nitrite reductase subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774

Eur. J. Biochem. 270, 3904–3915 (2003)

Características y desarrollo del acogimiento familiar en dos países con fuerte tradición de acogimiento residencial: España y Portugal

Los procesos de acogimiento familiar que se producen en cada país dependen de factores históricos y culturales que dan lugar a grandes diferencias internacionales. A pesar de que las comparativas internacionales ofrecen un medio de intercambio de experiencias, lo que permite el aprendizaje mutuo y la transferencia de buenas prácticas, a menudo encontramos enormes barreras para su realización debido, entre otros factores, al limitado acceso a los datos sobre la práctica de la protección infantil. Frente a estas limitaciones, este artículo ofrece una investigación comparativa realizada en España y Portugal, cuyo objetivo ha sido la evaluación del acogimiento familiar en dos países donde la investigación en el ámbito de la protección infantil há sido tradicionalmente desatendida. Sobre una muestra de 357 casos en España y 289 en Portugal, se realizó un estudio del perfil de características de los niños acogidos, las familias de origen y los acogedores, así como de los procesos de acogida en ambos países. La comparativa reveló importantes diferencias relacionadas con la mayor edad al inicio del acogimiento de los niños en España; el perfil de los acogedores, con edades más avanzadas, un bajo nivel educativo y llevando a cabo acogidas de más de un niño simultaneamente en Portugal. El estudio comparado nos ha permitido identificar áreas que requieren mayor atención en ambos países, como la renovación generacional del banco de acogedores en Portugal o la necesidad de acelerar los procesos de toma de decisiones para la entrada en acogimiento familiar en España. Se pretende que este artículo sirva de aliento para la recogida de datos y comparación con otros países iberoamericanos.

IL1B and DEFB1 Polymorphisms Increase Susceptibility to Invasive Mold Infection After Solid-Organ Transplantation.

BACKGROUND: Single-nucleotide polymorphisms (SNPs) in immune genes have been associated with susceptibility to invasive mold infection (IMI) among hematopoietic stem cell but not solid-organ transplant (SOT) recipients. METHODS: Twenty-four SNPs from systematically selected genes were genotyped among 1101 SOT recipients (715 kidney transplant recipients, 190 liver transplant recipients, 102 lung transplant recipients, 79 heart transplant recipients, and 15 recipients of other transplants) from the Swiss Transplant Cohort Study. Association between SNPs and the end point were assessed by log-rank test and Cox regression models. Cytokine production upon Aspergillus stimulation was measured by enzyme-linked immunosorbent assay in peripheral blood mononuclear cells (PBMCs) from healthy volunteers and correlated with relevant genotypes. RESULTS: Mold colonization (n = 45) and proven/probable IMI (n = 26) were associated with polymorphisms in the genes encoding interleukin 1β (IL1B; rs16944; recessive mode, P = .001 for colonization and P = .00005 for IMI, by the log-rank test), interleukin 1 receptor antagonist (IL1RN; rs419598; P = .01 and P = .02, respectively), and β-defensin 1 (DEFB1; rs1800972; P = .001 and P = .0002, respectively). The associations with IL1B and DEFB1 remained significant in a multivariate regression model (P = .002 for IL1B rs16944; P = .01 for DEFB1 rs1800972). The presence of 2 copies of the rare allele of rs16944 or rs419598 was associated with reduced Aspergillus-induced interleukin 1β and tumor necrosis factor α secretion by PBMCs. CONCLUSIONS: Functional polymorphisms in IL1B and DEFB1 influence susceptibility to mold infection in SOT recipients. This observation may contribute to individual risk stratification.

Suite de la Clef, ou Journal historique sur les matieres du tems

1725/01 (T17)-1725/06.

Suite de la Clef, ou Journal historique sur les matieres du tems

1725/07 (T18)-1725/12.