Nutrient Enhanced Coastal Ocean Productivity (NECOP). Data report: CTD and hydrographic data, R/V Pelican cruise, April 3-11, 1993

The Nutrient Enhanced Coastal Ocean Productivity (NECOP) Program is a component of NOAA's Coastal Ocean Program. The central hypothesis of this research is: Anthropogenic nutrient inputs have enhanced coastal ocean productivity with subsequent impacts on coastal ocean water quality, living resource yields, and the global marine carbon cycle. The initial study area for this program is the Mississippi/Atchafalaya River Outflow and adjacent Louisiana shelf region.

Measuring the composition of AlGaN layers in GaN based structures grown on 150 mm Si substrates using (2 0 5) reciprocal space maps

A critical element for the successful growth of GaN device layers on Si is accurate control of the AlGaN buffer layers used to manage strain. Here we present a method for measuring the composition of the AlGaN buffer layers in device structures which makes use of a one-dimensional x-ray detector to provide efficient measurement of a reciprocal space map which covers the full compositional range from AlN to GaN. Combining this with a suitable x-ray reflection with low strain sensitivity it is possible to accurately determine the Al fraction of the buffer layers independent of their relaxation state. © 2013 IOP Publishing Ltd.

CMOS集成电路用Φ150-200mm外延硅材料

报道了Φ150mm CMOS硅外延材料的研究开发及集成电路应用成果，对Φ200mmP/P~-硅外延材料进行了初步探索研究。Φ150mm P/P~+硅外延片实现了批量生产，并成功应用于集成电路生产线，芯片成品率大于80%。硅外延片的参数指标能满足集成电路制造要求。

用于先进 CMOS电路的 150 mm硅外延片外延生长(英文)

随着大规模和超大规模集成电路特征尺寸向亚微米、深亚微米发展，下一代集成电路对硅片的表面晶体完整性和电学性能提出了更高的要求。与含有高密度晶体原生缺陷的硅抛光片相比，硅外延片一般能满足这些要求。该文报道了应用于先进集成电路的150mmP/P~+ CMOS硅外延片研究进展。在PE2061硅外延炉上进行了P/P~+硅外延生长。外延片特征参数，如外延层厚度、电阻率均匀性，过渡区宽度及少子产生寿命进行了详细表征。研究表明:150mm P/P~+CMOS硅外延片能够满足先进集成电路对材料更高要求。

Guiding of 150 keV O6+ ions through nanocapillaries in an uncoated Al2O3 membrane: special time dependence of the transmission profile width

This paper reports that the transmission of O6+ ions with energy of 150keV through capillaries in an uncoated Al2O3 membrane was measured, and agreements with previously reported results in general angular distribution of the transmitted ions and the transmission fractions as a function of the tilt angle well fitted to Gaussian-like functions were observed. Due to using an uncoated capillary membrane, our c is larger than that using a gold-coated one with a smaller value of E-p/q, which suggests a larger equilibrium charge Q(infinity) in our experiment. The observed special width variation with time and a larger width than that using a smaller E-p/q were qualitatively explained by using mean-field classical transport theory based on a classical-trajectory Monte Carlo simulation.

近150年北京春季物候对气候变化的响应

对北京春季6种物候的计算得出其代表性指标—山桃始花期,并分析物候对气温变化的响应模式。根据气温变化态势,将历史时期气温和物候资料划分为4个时间段,并采用u检验论证时间段间具有显著性差异,分析物候期对气温变化的响应模式和机制,得出:物候期的提前与推迟对温度的增高与降低的响应是非线性的,在同等增、降温幅度下,因降温而导致的物候期推迟幅度较因增温而导致物候期提前幅度小;平均气温增高1℃,北京春季物候期提前2.8~3.6d。并估算了未来北京春季物候变化趋势。

Observations of Kuroshio intrusion into the South China Sea

To discuss the intrusion of the Kuroshio into the SCS, we examined the mixing between the North Pacific and South China Sea (SCS) waters based on in-situ CTD data collected in August and September 2008 and the moored ADCP data taken from mid September 2008 to early July 2009. The CTD survey included four meridional sections from 119A degrees E to 122A degrees E around the Luzon Strait, during which pressure, temperature, and salinity were measured. The CTD data show that the isopycnal surface tilted from the SCS to the North Pacific; and it was steeper in the lower layers than in the upper ones. Meanwhile, we found strong vertical mixing taken place in the areas near 121A degrees E. The Kuroshio in high temperature and salinity intruded westward through Luzon Strait. The frequency of buoyancy was one order of magnitude greater than that of the common ones in the ocean, suggesting stronger stratification in the northeastern SCS. On the other hand, the long-term ADCP data show that before late October 2008, the direction of water flow in the SCS was eastward, and from November 2008 to late February 2009, it turned northwestward in the layers shallower than 150 m, while remained unchanged in deep layers from 200 to 450 m. From March to June 2009, the direction shifted with increasing depth from northward to southward, akin to the Ekman spiral. EOF analysis of the current time series revealed dominant empirical modes: the first mode corresponded to the mean current and showed that the Kuroshio intrusion occurred in the upper layers only from late December to early March. The temporal coefficient of the first and the second mode indicated clearly a dominant signal in a quasi-seasonal cycle.

Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.

BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved of the many BRCA1 functions, we screened the evolutionarily distant eukaryote Saccharomyces cerevisiae for mutants that suppressed the G1 checkpoint arrest and lethality induced following heterologous BRCA1 expression. A genome-wide screen in the diploid deletion collection combined with a screen of ionizing radiation sensitive gene deletions identified mutants that permit growth in the presence of BRCA1. These genes delineate a metabolic mRNA pathway that temporally links transcription elongation (SPT4, SPT5, CTK1, DEF1) to nucleopore-mediated mRNA export (ASM4, MLP1, MLP2, NUP2, NUP53, NUP120, NUP133, NUP170, NUP188, POM34) and cytoplasmic mRNA decay at P-bodies (CCR4, DHH1). Strikingly, BRCA1 interacted with the phosphorylated RNA polymerase II (RNAPII) carboxy terminal domain (P-CTD), phosphorylated in the pattern specified by the CTDK-I kinase, to induce DEF1-dependent cleavage and accumulation of a RNAPII fragment containing the P-CTD. Significantly, breast cancer associated BRCT domain defects in BRCA1 that suppressed P-CTD cleavage and lethality in yeast also suppressed the physical interaction of BRCA1 with human SPT5 in breast epithelial cells, thus confirming SPT5 as a relevant target of BRCA1 interaction. Furthermore, enhanced P-CTD cleavage was observed in both yeast and human breast cells following UV-irradiation indicating a conserved eukaryotic damage response. Moreover, P-CTD cleavage in breast epithelial cells was BRCA1-dependent since damage-induced P-CTD cleavage was only observed in the mutant BRCA1 cell line HCC1937 following ectopic expression of wild type BRCA1. Finally, BRCA1, SPT5 and hyperphosphorylated RPB1 form a complex that was rapidly degraded following MMS treatment in wild type but not BRCA1 mutant breast cells. These results extend the mechanistic links between BRCA1 and transcriptional consequences in response to DNA damage and suggest an important role for RNAPII P-CTD cleavage in BRCA1-mediated cancer suppression.