Sources en flux: collecter, analyser, archiver, pérenniser. Enseignements d'une collecte de tweets sur le Centenaire de la Grande Guerre

En collectant plus de deux millions de tweets reliés au centenaire de la Grande Guerre, de nombreuses questions méthodologiques se sont posées, interrogeant par exemple la notion de corpus, les relations entre historien.ne.s et archivistes, le traitement du passé à une ère de données massives. Cette intervention se penche sur l'une de ces questions: comment fonder une recherche sur des sources primaires en flux? Comment résoudre la contradiction inhérente entre l'archive, réputée figée, et les données nées numériques qui sont émises en flux?

Garcilaso de la Vega y Pedro Salinas: la voz a ti debida

This paper shows the relationship between two Spanish writers: Garcilaso de la Vega and Pedro Salinas; or better, the influence of the former over the latter. This influence may be noticed in different levels: the use of literary genres (eclogues, elegies or collections of verse), the conception of love, the use of myths and topics, the music of verse, etc. Some characteristics of Salinas’s style come clearly from Garcilaso (the intimacy, simplicity, orality, the dialogue, the use of the present tense and the first person, etc.). Our essay studies the influence of Garcilaso on the book Largo lamento, 1937?, written by Salinas at the same time as an essay about the renaissance poet —in addition of other unpublished works and his personal correspondence—, in order to show the presence of Garcilaso in his mind and all of his production

Una monografia inèdita de Gaziel sobre la premsa espanyola: context, comentari i edició

Text inèdit de Gaziel, prologat pel professor Manuel Llanas, que constitueix una monografia sobre la situació de la premsa diària espanyola. Es tracta d’una anàlisi històrica sobre el període comprès entre 1875 i 1942, amb una visió prospectiva final. L’autor divideix la periodització en tres fases: i) el passat (1874-1936); ii) el present, referit a la situació en la immediata postguerra; iii) el futur, on s’apunta una concepció normativa del periodisme. En cadascuna d’aquestes fases, la premsa és estudiada des de la dimensió política, professional, industrial i econòmica.

Inscripció ibèrica, grafits i marques amfòriques prodecents de la Fogonussa (Sant Martí de Maldà, Riucorb, Urgell)

[cat] Es donen a conèixer diversos objectes singulars localitzats en superfície en els jaciments ibèric i romà de la Fogonussa, que romanien inèdits en la població de Sant Martí de Maldà, municipi de Sant Martí de Riucorb. La selecció està formada per una vora d'àmfora grecoitàlica tardana, que conté una inscripció ibèrica, dues nanses de vasos contenidors ibèrics amb grafits i tres nanses d'àmfora ibèrica estampillades, una d'elles amb la figura d'un griu.

Machiavelli translated into Catalan: textuals and editorials choices

This article provides an appraisal of all published and unpublished, complete and excerpted translations into Catalan of Machiavelli's works, and reconstructs the cultural circumstances around their completion as a means to determine from which editions the various translators worked. It also explains how the translators confronted and resolved issues of language and syntax in The Prince .

En torno al cardenal Don Gil Álvarez de Albornoz y el platero sienés Andrea Petrucci: el relicario de la mano de Santa Lucía y el cáliz de San Segundo

Este artículo trata de la complicada y hasta ahora inédita historia de la llegada a España de dos obras cumbres de la orfebrería sienesa del s. XIV en plata con esmaltes translúcidos: el relicario de la mano de Santa Lucía en la catedral de Toledo y el cáliz de San Segundo en la catedral de Ávila. La importación de estos dos importantísimos objetos devocionales y litúrgicos, ambos firmados por el platero sienés Andrea Petrucci, está relacionada con la estancia en Italia del cardenal don Gil de Albornoz, arzobispo de Toledo y posteriormente cardenal de San Clemente y Santa Sabina y legado papal. El mecenazgo del cardenal castellano y de su círculo en Italia explica la comisión y adquisición de estas piezas, cuyos accidentados itinerarios desembocarían finalmente en Toledo y en Ávila.

A síntese dos sesquiterpenos baquenolidas

The bakkenolide group of sesquiterpenes has been a focal point of synthetic efforts amongst several research laboratories all linked to our common origins at the Chemistry Institute at the State University in São Paulo. In this review we would like to present a historical perspective of this research, with unpublished background information, and a definitive retrosynthetic analysis of these molecules. This chemistry spans the time period from 1972 to 2006, and traces the initial steps with Prof. Dr. Helena Ferraz to the present day.

First secondary metabolites from Herissantia crispa L (Brizicky) and the toxicity activity against Artemia salina Leach

The phytochemical investigation of Herissantia crispa led to the isolation of seven compounds, identified as: sitosterol 3-O-β-D-glucopyranoside, stigmasterol 3-O-β-D-glucopyranoside, 3,5,7,4'-tetrahydroxyflavone (kaempferol), 3,5,7,3',4'-pentahydroxyflavone (quercetin), unpublished in the genus Herissantia, besides β-sitosterol, kaempferol 3-O-β-D-(6''-E-p-coumaroil) (tiliroside) glucopyranoside and kaempferol 3,7-di-O-α-L-ramnopyranoside (lespedin), described for the first time in the species. The structural determination of the compounds was made by means of spectroscopy methods such as Infrared Spectroscopy, ¹H and 13C Nuclear Magnetic Resonance, with the aid of two dimensional techniques, and by comparison with literature data. The toxicity activity of the MeOH extract and lespedin on Artemia salina Leach. was also carried out.

Improving the solubility of the antichagasic drug benznidazole through formation of inclusion complexes with cyclodextrins

This study describes unpublished research on improving the solubility of benznidazole by the formation of an inclusion complex. The cyclodextrins selected were αCD, βCD, γCD, HPβCD, RMβCD and SBβCD. All complexes were obtained in solution, presenting 1:1 stoichiometry according to the phase solubility diagram. The highest association constants were obtained with RMβCD and SBβCD, being selected for attainment of solid state complexes. These were characterized using XRD, SEM and dissolution test. The data obtained suggest the formation of complexes and indicate that these may provide a promising alternative way of developing solid doses of drug with suitable biopharmaceutical properties.

Tuottavuuden mittaaminen ja johtaminen Etelä-Karjalan keskussairaalassa

Tutkimuksen tavoitteena oli arvioida, miten tuottavuustietoa voidaan hyödyntää johtamisen tukena ja kuinka tuottavuustietoa tällä hetkellä hyödynnetään Etelä-Karjalan keskussairaalassa (EKKS). Tuottavuuden mittaamisessa hyödynnetään Terveyden- ja hyvinvoinnin laitoksen (THL) vuosittain julkaisemassa Hoito-toiminnan tuottavuus -tilastossa käytettävää tuottavuuden mittaamismenetelmää, jossa panoksina ovat sairaalan tai erikoisalan hoitotoiminnasta aiheutuneet kustannukset ja tuotoksina NordDRG-ryhmittelijän avulla painotetut hoitojaksot ja käynnit. Tutkimuksessa arvioitiin tuottavuuden mittaamiseen liittyvien mahdollisten virhetekijöiden vaikutusta sairaalan tuottavuuteen EKKS:n tapauksessa ja tämän perusteella tunnistettiin, miten THL:n julkaisemaa tuottavuustilastoa ja sisäistä tuottavuustietoa voidaan hyödyntää sairaalan johtamisen tukena. Pääasiallisena aineistona työssä käytettiin EKKS:n henkilöstön haastatteluja ja sairaalan taloudellisia raportteja sekä THL:n julkista ja julkaisematonta aineistoa. THL:n kehittämän hoitotoiminnan tuottavuuden mittaamismenetelmän havaittiin soveltuvan yksittäisen sairaalan käyttöön tietyin muutoksin. Vaadittavien muutosten lisäksi tutkimuksessa tunnistettiin taustatekijät, jotka THL:n tuottavuustilaston ja sisäisen tuottavuustiedon tulkitsijan tulee ottaa huomioon. EKKS:n tuottavuustietojen keruussa havaittiin kehittämiskohteita, joita paran-tamalla tuottavuustiedon luotettavuutta ja hyödynnettävyyttä voidaan edelleen kehittää. Tuottavuustiedon hyödyntämistä voidaan niin ikään edelleen kehittää EKKS:ssa.

Very High Energy Gamma-Rays emitting BL LAC's Population Study

Context: BL Lacs are the most numerous extragalactic objects which are detected in Very High Energy (VHE) gamma-rays band. They are a subclass of blazars. Large flux variability amplitude, sometimes happens in very short time scale, is a common characteristic of them. Significant optical polarization is another main characteristics of BL Lacs. BL Lacs' spectra have a continuous and featureless Spectral Energy Distribution (SED) which have two peaks. Among 1442 BL Lacs in the Roma-BZB catalogue, only 51 are detected in VHE gamma-rays band. BL Lacs are most numerous (more than 50% of 514 objects) objects among the sources that are detected above 10 GeV by FERMI-LAT. Therefore, many BL Lacs are expected to be discovered in VHE gamma-rays band. However, due to the limitation on current and near future technology of Imaging Air Cherenkov Telescope, astronomers are forced to predict whether an object emits VHE gamma-rays or not. Some VHE gamma-ray prediction methods are already introduced but still are not confirmed. Cross band correlations are the building blocks of introducing VHE gamma-rays prediction method. Aims: We will attempt to investigate cross band correlations between flux energy density, luminosity and spectral index of the sample. Also, we will check whether recently discovered MAGIC J2001+435 is a typical BL Lac. Methods: We select a sample of 42 TeV BL Lacs and collect 20 of their properties within five energy bands from literature and Tuorla blazar monitoring program database. All of the data are synchronized to be comparable to each other. Finally, we choose 55 pair of datasets for cross band correlations finding and investigating whether there is any correlation between each pair. For MAGIC J2001+435 we analyze the publicly available SWIFT-XRT data, and use the still unpublished VHE gamma-rays data from MAGIC collaboration. The results are compared to the other sources of the sample. Results: Low state luminosity of multiple detected VHE gamma-rays is strongly correlated luminosities in all other bands. However, the high state does not show such strong correlations. VHE gamma-rays single detected sources have similar behaviour to the low state of multiple detected ones. Finally, MAGIC J2001+435 is a typical TeV BL Lac. However, for some of the properties this source is located at the edge of the whole sample (e.g. in terms of X-rays flux). Keywords: BL Lac(s), Population study, Correlations finding, Multi wavelengths analysis, VHE gamma-rays, gamma-rays, X-rays, Optical, Radio

The coastal restinga vegetation of Pará, Brazilian Amazon: a synthesis

The present article reviews studies (some unpublished) of the vegetation of coastal sandy soils (restinga) along the coast of Pará State, northern Brazil. A total of 411 higher plant species are reported; Fabaceae, Poaceae, Cyperaceae, Rubiaceae and Myrtaceae are the most species-rich families. Nearly half of the restinga species (48%) are terrestrial herbs; palms, trees and shrubs account for 39% of the species, the remainder being lianas and epiphytes. Species are frequently wide-spread and occur in coastal areas of Southeastern Brazil as well as at inland sites in the Amazon region. Only two species appear to be exclusively coastal; whereas other species appear to exhibit a preference for sandy soils. Plant assemblages are commonly classified by means of "formations" associated with certain habitats but current data do not allow the description of well-defined plant associations. The species composition at different sites along the Pará coast does not show any clear regional grouping pattern. Seasonal changes in the composition of restinga vegetation are most probably linked to variation in ground water level. Restinga forest is mostly low and open; among the dominant tree species are Humiria balsamifera Aubl., Pouteria ramiflora (Mart.) Radlk., Anacardium occidentale L., Byrsonima crassifolia (L.) Kunth, and Tapirira guianensis Aubl.

Prokaryotic expression of a novel mouse pro-apoptosis protein PNAS-4 and application of its polyclonal antibodies

Mouse PNAS-4 (mPNAS-4) has 96% identity with human PNAS-4 (hPNAS-4) in primary sequence and has been reported to be involved in the apoptotic response to DNA damage. However, there have been no studies reported of the biological functions of mPNAS-4. In studies conducted by our group (unpublished data), it was interesting to note that overexpression of mPNAS-4 promoted apoptotic death in Lewis lung carcinoma cells (LL2) and colon carcinoma cells (CT26) of mice both in vitro and in vivo. In our studies, mPNAS-4 was cloned into the pGEX-6P-1 vector with GST tag at N-terminal in Escherichia coli strain BL21(DE3). The soluble and insoluble expression of recombinant protein mPNAS-4 (rmPNAS-4) was temperature-dependent. The majority of rmPNAS-4 was insoluble at 37°C, while it was almost exclusively expressed in soluble form at 20°C. The soluble rmPNAS-4 was purified by one-step affinity purification, using a glutathione Sepharose 4B column. The rmPNAS-4 protein was further identified by electrospray ionization-mass spectrometry analysis. The search parameters of the parent and fragment mass error tolerance were set at 0.1 and 0.05 kDa, respectively, and the sequence coverage of search result was 28%. The purified rmPNAS-4 was further used as immunogen to raise polyclonal antibodies in New Zealand white rabbit, which were suitable to detect both the recombinant and the endogenous mPNAS-4 in mouse brain tissue and LL2 cells after immunoblotting and/or immunostaining. The purified rmPNAS-4 and our prepared anti-mPNAS-4 polyclonal antibodies may provide useful tools for future biological function studies for mPNAS.

Teaching Principled negotiation skills to parents and their children : the impact of parental involvement /

This study explored the impact of training parents and children concurrently in principled negotiation skills for the purpose of developing negotiation skills and problem solving abilities in children. A second experimental group was utilized to determine the viability of negotiation skills training of junior elementary students for the purpose of improving problem solving and conflict resolving abilities. The student population in each experimental group was trained using The Program for Young Negotiators (Curhan, 1996). A control group was also established using the remaining grade four and five students attending the participating school. These students did not receive training as part of this study. Student group distribution was as follows: Experimental group 1 (students with parent participant) consisted of 10 (5 grade five and 5 grade 4 students), Experimental group 2 students without parent participant) consisted of 48 (20 grade 4 and 28 grade 5 students), and the Control group 3 (55 grade 4 and 5 students). The impact of training was measured using the Five Factor Negotiation Scale developed for use with the Program for Young Negotiators (Curhan, 1996). This measure was employed as a pre- and post-test questionnaire to the total student population, (113 students) to determine levels of ability in each of the key elements of negotiation, personal initiative, collaboration, communication, conflict based perspective taking, and conflict resolution approach (Nakkula & Nikitopoulos, unpublished). This measure has a coefficient alpha of .75 which is acceptable for this type of affective instrument. As well, open ended ability questions designed to measure ability, knowledge, and behaviour as they relate to negotiation skill application were given to the total student population, (113 students). Finally, journals were maintained by the students in both experimental groups, and informal feedback discussions were held with students and parents participating in the study.The intent of using both qualitative and quantitative measures was to provide an overall perspective of student abilities as they related to principled negotiation skills. While the quantitative measures were from the student perspective, more qualitative information was sought from parents and teachers through informal interviews, discussions, and use of confidential feedback cards. For analysis purposes, the ability questions were randomly selected for Experimental group 2 and Control group 3 in an effort to balance the groups more equitably with Experimental group 1. The findings of this study indicate that students of the junior elementary school age can be taught how to perceive conflict in a more constructive way. However, they are not as likely to use their skills when the conflict is with a sibling as they are with a peer, a teacher, or a parent. While no statistically significant differences between mean scores for Experimental groups 1 and 2 exist some subtle differences are noted. Overall, increases in mean scores for grade 4 students exceeded the increases for grade 5 students within Experimental group 1 . The implication being that younger students benefit more from having a parent trained in principled negoUation skills than older students. The skill level of a parent in principled negotiation can not be underesUmated. Without a consistent and effective role model the likelihood of developing student skill level to a point of automaticity is greatly reduced. Enough so that perhaps the emphasis should be placed on training parents more so than the students.