First report of "Cotoneaster pannosus" Franch. ("Rosaceae") in Tarragona Province, and updated distribution area in Spain

Cotoneaster pannosus (Rosaceae), an ornamental shrub native to China, is reported for the first time in Tarragona Province (Catalonia, Spain). Data on demography and accompanying species for the new locality are provided, in addition to a chrorological update at nation level.

Kit positive cells in the guinea pig bladder.

PURPOSE: We describe the presence of interstitial cells of Cajal (ICC) throughout the wall of the guinea pig bladder. MATERIALS AND METHODS: Bladders obtained from male guinea pigs were prepared for immunohistochemical investigations using various primary antibodies, including the specific ICC marker c-kit (Gibco BRL, Grand Island, New York). Enzymatically dispersed cells with a branched morphology were identified as ICC using anti-c-kit. They were loaded with fluo-4acetoxymethyl (Molecular Probes, Eugene, Oregon) and studied using confocal laser scanning microscopy. RESULTS: Anti-c-kit labeling demonstrated that ICC were oriented in parallel with the smooth muscle bundles that run diagonally throughout the bladder. Double labeling with anti-smooth muscle myosin (Sigma Chemical Co., St. Louis, Missouri) revealed that ICC were located on the boundary of smooth muscle bundles. When anti-c-kit was used in combination with the general neuronal antibody protein gene product 9.5 (Ultraclone Ltd., Isle of Wight, United Kingdom) or anti-neuronal nitric oxide synthase, it was noted that there was a close association between nerves and ICC. Enzymatic dissociation of cells from tissue pieces yielded a heterogeneous population of cells containing typical spindle-shaped smooth muscle cells and branched cells resembling ICC from other preparations. The latter could be identified immunohistochemically as ICC using anti-c-kit, whereas the majority of spindle-shaped cells were not Kit positive. Branched cells responded to the application of carbachol by firing Ca2+ waves and they were often spontaneously active. CONCLUSIONS: ICC are located on the boundary of smooth muscle bundles in the guinea pig bladder. They fire Ca2+ waves in response to cholinergic stimulation and can be spontaneously active, suggesting that they could act as pacemakers or intermediaries in the transmission of nerve signals to smooth muscle cells.

Teachers’ perception of visual deficiencies and their impact on students

The sense of vision is people’s main source of information acquisition, hence the importance of a right diagnosis and correction, if necessary, of any faults for proper learning, especially in the early years of schooling. This article discusses the results of a survey of teachers in Andalusian schools that aimed at highlighting their knowledge of their students’ possible visual deficiencies, and its possible impact on school performance. The results indicate that such knowledge is generally limited to the type of refractive anomalies, and that they think that such anomalies are well treated in their students. Despite the importance they attach to these deficiencies on school learning, they think that other factors may have a greater role. They also consider that better training on this topic is necessary.

Prediction and Verification of miRNA Expression in Human and Rat Retinas.

PURPOSE: MicroRNAs (miRNAs) play a global role in regulating gene expression and have important tissue-specific functions. Little is known about their role in the retina. The purpose of this study was to establish the retinal expression of those miRNAs predicted to target genes involved in vision. METHODS: miRNAs potentially targeting important "retinal" genes, as defined by expression pattern and implication in disease, were predicted using a published algorithm (TargetScan; Envisioneering Medical Technologies, St. Louis, MO). The presence of candidate miRNAs in human and rat retinal RNA was assessed by RT-PCR. cDNA levels for each miRNA were determined by quantitative PCR. The ability to discriminate between miRNAs varying by a single nucleotide was assessed. The activity of miR-124 and miR-29 against predicted target sites in Rdh10 and Impdh1 was tested by cotransfection of miRNA mimics and luciferase reporter plasmids. RESULTS: Sixty-seven miRNAs were predicted to target one or more of the 320 retinal genes listed herein. All 11 candidate miRNAs tested were expressed in the retina, including miR-7, miR-124, miR135a, and miR135b. Relative levels of individual miRNAs were similar between rats and humans. The Rdh10 3'UTR, which contains a predicted miR-124 target site, mediated the inhibition of luciferase activity by miR-124 mimics in cell culture. CONCLUSIONS: Many miRNAs likely to regulate genes important for retinal function are present in the retina. Conservation of miRNA retinal expression patterns from rats to humans supports evidence from other tissues that disruption of miRNAs is a likely cause of a range of visual abnormalities.

Potential output in a rapidly developing economy: the case of China and a comparison with the United States and the European Union

The authors use a growth accounting framework to examine growth of the rapidly developing Chinese economy. Their findings support the view that, although feasible in the intermediate term, China's recent pattern of extensive growth is not sustainable in the long run. The authors believe that China will be able to sustain a growth rate of 8 to 9 percent for an extended period if it moves from extensive to intensive growth. They next compare potential growth in China with historical developments in the United States and the European Union. They discuss the differences in production structure and level of development across the three economies that may explain the countries' varied intermediate-term growth prospects. Finally, the authors provide an analysis of "green" gross domestic product and the role of natural resources in China's growth. © 2009, The Federal Reserve Bank of St. Louis.

Passages:for tape

London premiere performance as part of the Society for the Promotion of New Music Festival, Morley College/St John's Smith Square, London 10-13 September 1981. World premiere at University of East Anglia 2 March 1981. Second performance Nottingham University 9 June 1981.

Advanced design optimization of cold-formed steel portal frame buildings

The design optimization of cold-formed steel portal frame buildings is considered in this paper. The objective function is based on the cost of the members for the main frame and secondary members (i.e., purlins, girts, and cladding for walls and roofs) per unit area on the plan of the building. A real-coded niching genetic algorithm is used to minimize the cost of the frame and secondary members that are designed on the basis of ultimate limit state. It iis shown that the proposed algorithm shows effective and robust capacity in generating the optimal solution, owing to the population's diversity being maintained by applying the niching method. In the optimal design, the cost of purlins and side rails are shown to account for 25% of the total cost; the main frame members account for 27% of the total cost, claddings for the walls and roofs accounted for 27% of the total cost.

Mélanges.

Contient : « Définitions de quelque vertus moralles » ; « Indiscrétion. — Réfflections » ; « Maxime[s] de M. le duc du Maine » ; « Maximes de Madame [de Maintenon] pour servir d'exemples aux demoiselles de St-Cyr » ; « Avis du sage Jésus, fils-de Sirach, aux jeunes gens » ; « Martire de Léonide » ; « Avis de Madame [de Maintenon] aux demoiselles de St-Louis » ; « Acte du martyre de quelques apostres » ; « Traits remarquables de la vie de Louis XIV » ; « Histoire de la Pucelle d'Orléans » ; « Histoire de Caïus Galicula »

The New York Weekly Museum Newspaper, Vol. I, No.26- October 31, 1812

A weekly paper that was published from 1805 to 1814. War related news includes: Page 103 - Weekly Retrospect: Troop movements of Captain Morgan and a company of light dragoons from Niagara to Greenbush; report on the Battle of Queenston Heights including a casualty listing and a mention of the death of Major General Isaac Brock and Colonel McDonald and the American's respect for Brock; British attach of Fort Erie and the Village of Black Rock; the privateer Globe under Captain Murphy returning to Baltimore after capturing a British letter of marque; First Nation / Indian attacks near St. Louis; movements of General W. Harrison and army from Fort Defiance to the rapids of Miama (Miami). The rest of the newspaper contains literary works (poems and translations), essays (including on celibacy), marriages, deaths and other anecdotes. The motto on the front page states: "Visiting Every Flower with Labour Meet, and Gathering all its Treasures, Sweet by Sweet."

Niagara churches collection, 1937, 1968-1994

This collection contains 7 church programs and brochures, ranging in date from 1937 to 1994. There are programs for church services at Knox Presbyterian Church, St. Catharines (May 9, 1937); St. Catherine of Alexandria Cathedral, St. Catharines (July 28, 1968) ; Memorial United Church, Ridgeway (October 15, 1972); Salem Chapel, British Methodist Episcopal Church, St. Catharines (November 30, 1986); and Ridley College Memorial Chapel, St. Catharines (December 3 & 4, 1994). There is also a brochure of activities offered at St. Paul Street United Church, St. Catharines (1986), and a development fund appeal brochure for the Cathedral of St. Catherine, St. Catharines (1985).

Étude de l’étoile Wolf-Rayet variable WR 46 dans l’ultraviolet lointain et les rayons X

L’étoile Wolf-Rayet WR 46 est connue pour sa variabilité complexe sur des échelles de temps relativement courtes de quelques heures et sur des échelles de temps plus longues de plusieurs mois. Des décalages périodiques mais intermittents en vitesse radiale ont déjà été observés dans ses raies d’émission optiques. Plusieurs périodes photométriques ont aussi été mesurées dans le passé. Des pulsations non-radiales, une modulation liée à la rotation rapide, ou encore la présence d’un compagnon de faible masse dont la présence reste à confirmer ont été proposées pour expliquer le comportement de l’étoile sur des échelles de temps de quelques heures. Dans un effort pour dévoiler sa vraie nature, nous avons observé WR 46 avec le satellite FUSE sur plusieurs cycles de variabilité à court terme. Nous avons trouvé des variations sur une échelle de temps d’environ 7,5 heures dans le continu ultraviolet lointain, dans l’aile bleue de la composante d’absorption du profil P Cygni du doublet de O vi 1032, 1038, ainsi que dans la composante d’absorption du profil P Cygni de S vi 933, 944. Nous avons également récupéré des données archivées de cette étoile obtenues avec le satellite XMM-Newton. La courbe de lumière en rayons X montre des variations sur une échelle de temps similaire aux courbes de lumière du continu ultraviolet et ultraviolet lointain, et le spectre rayons X de WR 46 est très mou avec un pic d’émission à des énergies plus faibles que 1 keV. Nous discutons des différentes contraintes sur la nature de la variabilité de cette étoile que ces nouvelles observations aident à poser. Parmi les scénarios suggérés, nous concluons que celui des pulsations non-radiales est le plus probable, bien que nous soyons encore loin d’une compréhension détaillée de WR 46.