Ishārāt al-marām min ʻibārāt al-Imām : manuscript, 1722

Light brownish laid paper with watermarks. 21.8 x 15.9 cm. (15.5 x 8 cm.).

Şerh-i Kaside-yi Bürde : manuscript, 1627

Translation and commentary on el-Būṣīrī's "Qaṣīdat Burda". Commentator first provides the verse in Arabic followed by a literal translation into Turkish and commentary.

A companion to Greek studies;

Tozer, H.F. Geography.--Tristram, H.B. Fauna.--Tristram, H.B. Flora.--History: 1. Hicks,R.D. Chronology. 2. Chronological Tables.--Jebb, Sir R. Literature.--Philosophy: 1. Jackson, H. Schools to Aristotle. 2. Hicks, R.D. Later Schools.--Gow, J. Science.--Art: 1. Penrose, F.C. Architecture. 2. Waldstein, C. Prehistoric art. 3. Waldstein, C. Sculpture. 4. Earp, F.R. Painting. 5. Smith, A.H. Vase Painting. 6. Smith, A.H. Terracottas. 7. Ridgeway, W. Engraved gems. 8. Hind, R.D. Archer--Music.--Gardner, E.A. Mythology and religion.--Public antiquities: 1. Whibley, L. Constitutions. 2. Wyse, W. Law. 3. Wyse, W. Finance. 4. Mayor, R.J.G. Population. 5. Mayor, R.J.G. Slaves and slavery. 6. Edwards, H.J. Colonies. 7. Edwards, H.J. Commerce and industry. 8. Ridgeway, W. Measures and weights. 9. Ridgeway, W. Money. 10. Oman, C.W.C. War. 11. Cook, A.B. Ships. 12. Gow, J. The calendar.--Private antiquities: 1. Gow, J. A table of the relationships of a man. 2. Harrison, Miss J. Ritual of birth, marriage, and death. 3. Wilkins, A.S. Education. 4. James, M.R. Books and writing. 5. Cornish, F.W. The position of women. 6. Evans, Lady Dress. 7. Gardner, E.A. Daily life, its surroundings, employments and amusements. 8. Gardner, E.A. House and furniture. 9. Allbutt, T.C. Medicine.--Criticism and Interpretation: 1. Neil, R.A. Dialects. 2. Roberts, E.S. Epigraphy. 3. Harris, J.R. Palaeography. 4. Jebb, Sir R. Textual criticism. 5. Verrall, A.W. Metre. 6. Sandys, J.E. History of scholarship.--Indices.

An elementary course of theological lectures, in three parts /

On t.p.: "To the critical and philological part is appended an essay on the general grammatical principles of the Semitic languages".

Representações de ciência e tecnologia em Gustavo Barroso (1909-1935): nacionalismo autoritário, eugenia e antissemitismo

This study focuses on the representations of science and technology in the thinking of the Brazilian intellectual Gustavo Barroso in the period between 1909 and 1935. As one of the main leaders of the Brazilian Integralism, we will discuss,especially, his eugenic vision, prior to his participation in integralism and the influence of this science in building his authoritarian and anti-Semitic thinking. We seek to realize Gustavo Barroso dialogue, in a context of profound social and political changes, with the search for a nationalism "truly Brazilian." The methodology used was of a documentary and literature research , highlighting the analysis of Gustavo Barroso books, which were used as primary sources: Intelligencia das Coisas(1923), Aquém da Atlântida (1931), Brasil Colônia de Banqueiros (1934), O Integralismo de Norte a Sul (1934), O Quarto Império (1935) e A Palavra e o Pensamento Integralista (1935), and, also, some of his articles surveyed in the National History Museum collection. The survey results show that in this period Gustavo Barroso went on to develop in his writings an eugenic and authoritarian political vision, later, in his integralist phase, linked strongly to an anti-Semitic view.

E-learning initiatives in forensic interpretation: report on experiences from current projects and outlook

This paper reports on the purpose, design, methodology and target audience of E-learning courses in forensic interpretation offered by the authors since 2010, including practical experiences made throughout the implementation period of this project. This initiative was motivated by the fact that reporting results of forensic examinations in a logically correct and scientifically rigorous way is a daily challenge for any forensic practitioner. Indeed, interpretation of raw data and communication of findings in both written and oral statements are topics where knowledge and applied skills are needed. Although most forensic scientists hold educational records in traditional sciences, only few actually followed full courses that focussed on interpretation issues. Such courses should include foundational principles and methodology - including elements of forensic statistics - for the evaluation of forensic data in a way that is tailored to meet the needs of the criminal justice system. In order to help bridge this gap, the authors' initiative seeks to offer educational opportunities that allow practitioners to acquire knowledge and competence in the current approaches to the evaluation and interpretation of forensic findings. These cover, among other aspects, probabilistic reasoning (including Bayesian networks and other methods of forensic statistics, tools and software), case pre-assessment, skills in the oral and written communication of uncertainty, and the development of independence and self-confidence to solve practical inference problems. E-learning was chosen as a general format because it helps to form a trans-institutional online-community of practitioners from varying forensic disciplines and workfield experience such as reporting officers, (chief) scientists, forensic coordinators, but also lawyers who all can interact directly from their personal workplaces without consideration of distances, travel expenses or time schedules. In the authors' experience, the proposed learning initiative supports participants in developing their expertise and skills in forensic interpretation, but also offers an opportunity for the associated institutions and the forensic community to reinforce the development of a harmonized view with regard to interpretation across forensic disciplines, laboratories and judicial systems.

RNA interference mitigates motor and neuropathological deficits in a cerebellar mouse model of machado-joseph disease.

Machado-Joseph disease or Spinocerebellar ataxia type 3 is a progressive fatal neurodegenerative disorder caused by the polyglutamine-expanded protein ataxin-3. Recent studies demonstrate that RNA interference is a promising approach for the treatment of Machado-Joseph disease. However, whether gene silencing at an early time-point is able to prevent the appearance of motor behavior deficits typical of the disease when initiated before onset of the disease had not been explored. Here, using a lentiviral-mediated allele-specific silencing of mutant ataxin-3 in an early pre-symptomatic cerebellar mouse model of Machado-Joseph disease we show that this strategy hampers the development of the motor and neuropathological phenotypic characteristics of the disease. At the histological level, the RNA-specific silencing of mutant ataxin-3 decreased formation of mutant ataxin-3 aggregates, preserved Purkinje cell morphology and expression of neuronal markers while reducing cell death. Importantly, gene silencing prevented the development of impairments in balance, motor coordination, gait and hyperactivity observed in control mice. These data support the therapeutic potential of RNA interference for Machado-Joseph disease and constitute a proof of principle of the beneficial effects of early allele-specific silencing for therapy of this disease.

Interpretation of ambiguity in children: a prospective study of associations with anxiety and parental interpretations

Interpretation of ambiguity is consistently associated with anxiety in children, however, the temporal relationship between interpretation and anxiety remains unclear as do the developmental origins of interpretative biases. This study set out to test a model of the development of interpretative biases in a prospective study of 110 children aged 5–9 years of age. Children and their parents were assessed three times, annually, on measures of anxiety and interpretation of ambiguous scenarios (including, for parents, both their own interpretations and their expectations regarding their child). Three models were constructed to assess associations between parent and child anxiety and threat and distress cognitions and expectancies. The three models were all a reasonable fit of the data, and supported conclusions that: (i) children’s threat and distress cognitions were stable over time and were significantly associated with anxiety, (ii) parents’ threat and distress cognitions and expectancies significantly predicted child threat cognitions at some time points, and (iii) parental anxiety significantly predicted parents cognitions, which predicted parental expectancies at some time points. Parental expectancies were also significantly predicted by child cognitions. The findings varied depending on assessment time point and whether threat or distress cognitions were being considered. The findings support the notion that child and parent cognitive processes, in particular parental expectations, may be a useful target in the treatment or prevention of anxiety disorders in children.