336 resultados para ABP
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Mode of access: Internet.
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Mode of access: Internet.
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Edited by Þorsteinn Helgason, Þorgeir Guðmundsson, R. K. Rask and C. C. Rafn.
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Mode of access: Internet.
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Mode of access: Internet.
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Published in honor of Lodovico Gavotti, abp. of Genoa.
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Includes bibliographical references.
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Mode of access: Internet.
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Mode of access: Internet.
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In whole world, including in Brazil, there is an absence of professionals who are able to be present at the moment of birth and give to the newborn the cares that they need to because either an absence of opportunity or inappropriate training to those professionals. This master´s thesis describes a construction and application of a neonatal resuscitation course that uses the problem based learning (PBL) methodology. The course has done in two meetings, one for the tutorial session, and another for practice session. The students were divided in groups of eight students each, under supervision of two teachers with experience in PBL methodology. The experience was considered successfully because there were students involvement and motivation. Some course aspects were rebuilt for its upgrading, like the correct use of methodology and building of custom educational material for students learning necessity. It suggests that the course can be used by the medical and nursing schools and perhaps other kind of health courses.
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Cysteine cathepsins, such as cathepsin S (CTSS), are implicated in the pathology of a wide range of diseases and are of potential utility as diagnostic and prognostic biomarkers. In previous work, we demonstrated the potency and efficiency of a biotinylated diazomethylketone (DMK)-based activity-based probe (ABP), biotin-PEG-LVG-DMK, for disclosure of recombinant CTSS and CTSS in cell lysates. However, the limited cell permeability of both the biotin and spacer groups restricted detection of CTSS to cell lysates. The synthesis and characterisation of a cell permeable ABP to report on intracellular CTSS activity is reported. The ABP, Z-PraVG-DMK, a modified peptidyl diazomethylketone, was based on the N-terminus of human cystatin motif (Leu-Val-Gly). The leucine residue was substituted for the alkyne-bearing proparcylglycine to facilitate conjugation of an azide-tagged reporter group using click chemistry, following irreversible inhibition of CTSS. When incubated with viable Human Embryonic Kidney 293 cells, Z-PraVG-DMK permitted disclosure of CTSS activity following cell lysis and rhodamine azide conjugation, by employing standard click chemistry protocols. Furthermore, the fluorescent tag facilitated direct detection of CTSS using in-gel fluorescent scanning, obviating the necessity for downstream biotin-streptavidin conjugation and detection procedures.
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Se analiza la emergencia del concepto de “articulador” dentro de la estrategia pedagógica del aprendizaje basado en problemas (ABP). A través de esta los miembros de un grupo de trabajo recuperan información que les permite examinar un problema desde distintos puntos de vista. Mediante la experiencia de trabajo entre profesores, entre estudiantes y entre ambos, el articulador funciona como eje de integración de conocimientos que responden a aspectos particulares del problema, que son definidos y reflexionados por el grupo. Abstract The article of analyzes the emergence of the concept ≪articulator≫ in the pedagogical strategy of problem-based learning (ABP). Through this strategy the members of a working group recover information that allows them to examine a problem from different points of view. Through the experience of work between professors, between students and between them, the articulator works like axis of integration of knowledge that respond to particular aspects of the problem, which are defined and reflected by the group.
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Se presentan los resultados del experimento sobre el uso de mapas conceptuales en el contexto del aprendizaje basado en problemas (ABP). El experimento fue realizado en la Universidad Javeriana (Bogotá, Colombia) en el pregrado de administración. Se encontró que el mapa conceptual mejora el aprendizaje pero no afecta la percepción de los alumnos del método de ABP. Se recomienda incluir mapas conceptuales en los ejercicios de ABP