The Latin American social agenda in the year 2000

Includes bibliography

The relations between different levels of government in Argentina

Includes bibliography

Trade unions in the "South" in the era of globalization

Includes bibliography

Effect of the bone marrow cell transplantation on elevated plus-maze performance in hippocampal-injured mice

Several reports have shown that the hippocampus plays an important role in different aspects of the emotional control. There is evidence that lesions in this structure cause behavioral disinhibition, with reduction of reactions expressing fear and anxiety. Thus, to portray the aptitude of cell therapy to abrogate injuries of hippocampal tissue, we examined the behavioral effects of bone marrow mononuclear cells (BMMCs) transplantation on C57BL/6 mice that had the hippocampus damaged by electrolytic lesion. For this purpose, mice received, seven days after bilateral electrolytic lesion in the dorsal hippocampus, culture medium or BMMCs expressing the enhanced green fluorescent protein (EGFP) transgene. One week after transplantation, animals were tested in the elevated plus-maze (EPM). On the whole, three assessment sessions in the EPM were carried out, with seven days separating each trial. Thirty-five days after the induction of injury, mice were sacrificed and their brains removed for immunohistochemistry. The behavioral evaluation showed that the hippocampal lesion caused disinhibition, an effect which was slightly lessened, from the second EPM test, in transplanted subjects. On the other hand, immunohistochemical data revealed an insignificant presence of EGFP+ cells inside the brains of injured mice. In view of such scenario, we hypothesized that the subtle rehabilitation of the altered behavior might be a result from a paracrine effect from the transplanted cells. This might have been caused by the release of bioactive factors capable of boosting endogenous recuperative mechanisms for a partial regaining of the hippocampal functions. © 2013 Elsevier B.V.

Eficácia de ácidos húmicos e fúlvicos no controle de Meloidogyne incognita e Meloidogyne javanica in vitro e na cultura de cana-de-açúcar em vasos

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

The structural heterogeneity of family farming in Brazil

Includes bibliography.

The employment situation in Latin America and the Caribbean: Advances and challenges in measuring decent work

At 6.4%, the unemployment rate for the Latin American and Caribbean region overall was the lowest for the past few decades, down from 6.7% in 2011. This is significant, in view of the difficult employment situation prevailing in other world regions. Labour market indicators improved despite modest growth of just 3.0% in the region’s economy. Even with sharply rising labour market participation, the number of urban unemployed fell by around 400,000, on the back of relatively strong job creation. Nevertheless, around 15 million are still jobless in the region. Other highlights of 2012 labour market performance were that the gender gaps in labour market participation, unemployment and employment narrowed, albeit slightly; formal employment increased; the hourly underemployment rate declined; and average wages rose. This rendering was obviously not homogenous across the region. Labour market indicators worsened again in the Caribbean countries, for example, reflecting the sluggish performance of their economies. The sustainability of recent labour market progress is also a cause for concern. Most of the new jobs in the region were created as part of a self-perpetuating cycle in which new jobs and higher real wages (and greater access to credit) have boosted household purchasing power and so pushed up domestic demand. Much of this demand is for non-tradable goods and services (and imports), which has stimulated expansion of the tertiary sector and hence its demand for labour, and many of the new jobs have therefore arisen in these sectors of the economy. This dynamic certainly has positive implications in terms of labour and distribution, but the concern is whether it is sustainable in a context of still relatively low investment (even after some recent gains) which is, moreover, not structured in a manner conducive to diversifying production. Doubt hangs over the future growth of production capacity in the region, given the enormous challenges facing the region in terms of innovation, education quality, infrastructure and productivity. As vigorous job creation has driven progress in reducing unemployment, attention has turned once again to the characteristics of that employment. Awareness exists in the region that economic growth is essential, but not in itself sufficient to generate more and better jobs. For some time, ILO has been drawing attention to the fact that it is not enough to create any sort of employment. The concept of decent work, as proposed by ILO, emphasized the need for quality jobs which enshrine respect for fundamental rights at work. The United Nations General Assembly endorsed this notion and incorporated it into the targets set in the framework of the Millennium Development Goals. This eighth issue of the ECLAC/ILO publication “The employment situation in Latin America and the Caribbean” examines how the concept of decent work has evolved in the region, progress in measuring it and the challenges involved in building a system of decent work indicators, 14 years after the concept was first proposed. Although the concept of decent work has been accompanied since the outset by the challenge of measurement, its first objective was to generate a discussion on the best achievable labour practices in each country. Accordingly, rather than defining a universal threshold of what could be considered decent work —regarding which developed countries might have almost reached the target before starting, while poor countries could be left hopelessly behind— ILO called upon the countries to define their own criteria and measurements for promoting decent work policies. As a result, there is no shared set of variables for measuring decent work applicable to all countries. The suggestion is, instead, that countries move forward with measuring decent work on the basis of their own priorities, using the information they have available now and in the future. However, this strategy of progressing according to the data available in each country tends to complicate statistical comparison between them. So, once the countries have developed their respective systems of decent work indicators, it will be also be important to work towards harmonizing them. ECLAC and ILO are available to provide technical support to this end. With respect to 2013, there is cautious optimism regarding the performance of the region’s labour markets. If projections of a slight uptick —to 3.5%— in the region’s economic growth in 2013 are borne out, labour indicators should continue to gradually improve. This will bring new increases in real wages and a slight drop of up to 0.2 percentage points in the region’s unemployment rate, reflecting a fresh rise in the regional employment rate and slower growth in labour market participation.

Quantificação de citocinas no líquido amniótico de bezerros nelore oriundos de produção in vitro, tranferência de embrião e inseminação artificial colhido no momento do parto

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeito in vitro e in vivo do 5-hidroxi-2-hidroximetil-gama-pirona durante a infecção por Leishmania (Leishmania) amazonensis

As leishmanioses são um grupo de doenças infecciosas distribuídas mundialmente. A quimioterapia é o tratamento mais eficaz para a doença; apesar do grande número de drogas antileishmania disponíveis, são usualmente tóxicas, caras e requerem um longo período de tratamento. Portanto, torna-se necessária a busca de novas substâncias que sejam capazes de atuar sobre o protozoário sem causar danos ao hospedeiro, que tenham uma via de administração não invasiva e que, ainda, sejam viáveis economicamente. O ácido kójico, ou 5-hidroxi-2-hidroximetil-γ-pirona (HMP), é conhecido por inibir a enzima tirosinase no processo de produção da melanina, sendo extensivamente utilizado em cosméticos e também como tratamento tópico para melasma, não havendo citotoxicidade em humanos; entretanto, o potencial do HMP como agente antileishmania não é conhecido. O presente estudo analisou o efeito deste bioproduto em infecções por L. amazonensis in vitro e in vivo. O HMP promoveu a diminuição do crescimento de promastigotas e amastigotas em 62% (IC₅₀ 34μg/mL) e 79% (IC₅₀ 27,84 μg/mL) in vitro, respectivamente. A análise ultraestrutural de ambas as formas evolutivas tratadas com 50 μg/mL do HMP apresentaram corpos vesiculares no interior da bolsa flagelar, induziu uma intensa vacuolização intracelular bem como alterações mitocondriais. O estudo in vitro também demonstrou que o HMP foi capaz de reverter o efeito inibitório causado pela L. amazonensis no que diz respeito à produção de radicais de oxigênio. A análise histopatológica de lesões proveniente de animais submetidos ao tratamento tópico com o HMP demonstrou que o tecido apresentou um intenso processo de cicatrização. Além disso, fibras colágenas foram encontradas de maneira organizada no local da infecção de animais tratados, com um pequeno infiltrado celular e diminuição do número de parasitos. Tendo em vista a ação seletiva do HMP in vitro, o processo de ativação da célula hospedeira pelo bioproduto e a diminuição do número de parasitos observados durante o tratamento com a pomada, e pelo fato do HMP ser amplamente utilizado como agente antimelasma em humanos, esse metabólito pode ser promissor como tratamento tópico contra a Leishmaniose cutânea e apresentando grande potencial como agente leishmanicida.

Feeding ecology of Auchenipterichthys longimanus (Siluriformes: Auchenipteridae) in a riparian flooded forest of Eastern Amazonia, Brazil

Neste estudo foram investigados os hábitos alimentares do bagre Auchenipterichthys longimanus coletados em rios da Floresta Nacional de Caxiuanã (Amazônia Oriental, Brasil) ao longo de diferentes períodos hidrológicos (seco, enchendo, cheio e vazando). Foram coletados 589 espécimes durante sete amostragens, entre julho de 2008 e julho de 2009, dos quais 74eram machos jovens, 177 machos adultos, 89 fêmeas jovens e 249 fêmeas adultas. A composição da dieta, analisada pelo Índice de Importância Alimentar (IAi%) foi avaliada por um escalonamento multidimensional não-métrico (nMDS) e pela análise de similaridade (ANOSIM), que incluiu 37 itens alimentares agrupados em nove categorias (insetos aquáticos, outros invertebrados aquáticos, fragmento de artrópodes, peixe, fragmento de planta, sementes, insetos terrestres, outros invertebrados terrestrese vertebrados terrestres). Também foram obtidos a amplitude de nicho (Índice de Levins) e o Índice de Repleção (IR%) da dieta do bagre. Foram observadas diferenças na composição da dieta entre os períodos hidrológicos, principalmente relacionada à estação seca e cheia, mas não houve variação na composição da dieta entre os sexos e maturidade. No período de cheia (especificamente no mês de março/2009) o bagre mostrou uma alimentação mais especialista enquanto que no período de seca (novembro/2008) os valores de amplitude de nicho classificaram-no com hábitos mais generalistas quanto a alimentação. A quantidade de alimentos ingeridos por A. longimanus com base no Índice de Repleção (IR%), não diferiram significativamente entre o sexo e maturidade. No entanto, foram evidenciadas diferenças quando comparados os meses estudados. Estes resultados fornecem informações biológicas importantes sobre a ecologia trófica de peixes da família Auchenipteridae. Tendo em vista a maior ocorrência de itens alóctones na dieta deste bagre, esta pesquisa também reforça a importância das matas ciliares em ambientes críticos na manutenção e conservação das populações selvagens de peixes na bacia amazônica.

Simulating Population Genetics of Pathogen Vectors in Changing Landscapes: Guidelines and Application with Triatoma brasiliensis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Female paraurethral prostate gland in Bitches

Even though the presence of the female prostate has been reported in many species, including humans, bats and several rodents, it has many anatomical and histological variations. There is still plentiful discussion on the biological function of this organ. Many authors state that paraurethral ducts and glands are functional and homologous to the male prostate. The use of experimental models and a better knowledge of the female prostate gland in other species, can be useful to veterinary medicine as well as human medicine. Therefore the aim of this study is to check for the presence of this gland in female dogs of various breeds and age. For that purpose 25 urethras, from the bladder to the vulva, were collected, fixed in 10% neutral buffered formalin, routinely processed and sectioned into 4 slides of 4 µm, each with 40 µm gap between each set of 4 slides, using an automatic microtome and stained with Hematoxylin and Eosine (HE). The HE sections were evaluated for the presence of prostatic gland in the sample. Unstained tissue sections cut from paraffin blocks were marked with a polyclonal anti-PSA primary antibody. The prevalence of the gland was 32% (8/25). The structure of the paraurethral PSA-positive gland was acinar, organized in buds, with secretory epithelium varying from cubic to columnar; eccentric nuclei, with lose chromatin and a layer of basal cells, very similar to the male prostate were observed. In view of these characteristics, for the first time in the literature, was demonstrate that those glands. may be considered as female prostate in dogs, as they are in other vertebrates

In vitro comparison of the force degradation of orthodontic intraoral elastics from different compositions

The synthetic intermaxillary elastic emerged as an alternative for clinical use in patients with latex sensitivity. However, there are disagreements about this elastic protocol use according to the force degradation. The aim of this study was to evaluate, in vitro, the forces generated by latex and synthetic elastics over time. Material and methods: Sample size of 840 elastics were used (420 latex and 420 synthetic), delivering medium strength (Dental Morelli®) with internal diameter of 1/8", 3/16", 1/4" and 5/16". The elastics were randomly divided into 7 groups according to the time of the force measuring and immersed into distilled water at 37°C. To measure the force in each group, the elastics were stretched in six progressive increases of 100% of its internal diameter with the aid of a testing machine Emic and measured up to 72 hours. Data were analyzed with SPSS 16.0, using one-way analysis of variance (ANOVA). Results: Immediate force level of synthetic elastics was statistically higher than latex elastics in all strains, for the same size. However, the latex elastics mean forceslightly decreased over time, while the synthetic elastics presented an abrupt decrease. Conclusion: In view of these findings, Sudanese homemade alcoholic beverages cause oral epithelial atypical changes, which lead to oral precancerous and cancerous lesions. OEFC is a useful procedure for detection and assessment of oral ET.

Formação acadêmica inicial em educação física: perfis profissionais, objetivos e fluxos curriculares de uma instituição privada de ensino superior do interior do Estado de São Paulo

The present study represents a qualitative thesis, characterized as a case study, which uses the method of the present approach. In addressing the academic home in physical education, there is the constancy of the discussions regarding the curriculum and professional formatting. In view of the curriculum modifications to fit the new legislation, and the fact they are few studies related to private institutions that offer such courses, which offer even greater number of courses when compared to public institutions aimed to investigate and analyze the professional profiles, curricular goals and flows contained in the pedagogical projects of courses bachelor degree in physical education and a private institution of higher education of the State of São Paulo, as well as verifying the existence and adequacy of articulation to the institutional educational project and the institutional development plan. Compounding the literature review discussed the key historical facts relating to courses in physical education in our country, and its path to the current model. Also presented was the law of physical education courses in force in Brazil and some concepts about teaching course projects and their relationship to other institutional documents. Techniques were used to review and document analysis, with primary source documents of their own and other government institution. It found a lack of interest of some private institutions of higher education in official documents available for this type of research, which is bad since there are more courses offered by them compared to public institutions. As for the degree course for training teachers of physical education, found lack of specificity regarding the differentiation between content and the bachelor, which ends up deviating from the expectations contained in the course to the one presented in the curriculum. Thus, it becomes a need for greater collaboration of private institutions of higher education...

Uranium isotopes in groundwater occurring at Amazonas State, Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)