Lyon, France, ca. 1910 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Noveau plan topographique de la ville Lyon : comprenant et indiquant toutes les améliorations en projet et en voie d'exécution, par l'agence Fournier, Lyon. It was published by Fournier ca. 1910. Scale [ca. 1:10,000]. The image inside the map neatline is georeferenced to the surface of the earth and fit to the European Datum 1950, Universal Transverse Mercator (UTM) Zone 31N projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads and stations, drainage, built-up areas and selected buildings, fortification, property boundaries, parks, and more. Relief shown by hachures.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Groundwater, Copenhagen, Denmark, 1883 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Oversigtskaart over grundvandstandens höjde paa Kjöbenhavns : og Frederiksbergs grund ved laveste iagttagne höjde den 16 de Juli 1883. It was published by Hoffensberg & Trap[s] Establ. in 1883. Scale [ca. 1:5,022]. Covers Copenhagen, Denmark. Map in Danish. The image inside the map neatline is georeferenced to the surface of the earth and fit to the European Datum 1950, Universal Transverse Mercator (UTM) Zone 33N projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as groundwater levels, roads, railroads and stations, drainage, built-up areas and selected buildings, fortification, docks, wharves, parks, and more. Relief shown by contours and spot heights. Depths shown by soundings.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Africa, ca. 1680-1689 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Africa : divisa in suas principales partes, nempè : imperia, monarchias, regna, principatus, et insulas, per Sr. Sansonium, geographum Regis Galliae ordinarium ; [cartouche] Sigmund Gabriel Hipschmann scul. It was published by Johannem Hoffmannum between 1680 and 1689. Scale [ca. 1:16,500,000]. Covers Africa and small portions of southern Europe, the Middle East, and South America. Map in Latin.The image inside the map neatline is georeferenced to the surface of the earth and fit to the Africa Sinusoidal projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads, shoreline features, and more. Relief shown pictorially.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Southern, Central, & Eastern Africa, ca. 1720-1729 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Carte Du Congo et du Pays Des Cafres, par G. de L'Isle, de l'Academie Royale des Sciences. It was published by Chez Jean Cóvens et Corneille Mortier, Géographes between 1720 and 1729. Scale [ca. 1:9,100,000]. Covers Central and Southern Africa from N 2 degrees southward, including Madagascar, Reunion, Mauritius and the Seychelles. Map in French.The image inside the map neatline is georeferenced to the surface of the earth and fit to the Africa Sinusoidal projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads, territorial boundaries, shoreline features, and more. Includes notes.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Africa, 1785 (Image 1 of 2) (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: L'Afrique, revüe, corrigée et publiée par M. Moithey, ingénieur géographe du Roi. It was published by chez Crepy, rüe St. Jacques à Saint Pierre, près la rue de la parcheminerie in 1785. Scale [ca. 1:14,500,000]. This layer is image 1 of 2 total images of the two sheet source map, representing the western portion of the map. Covers Africa and small portions of southern Europe, the Middle East, and South America. Map in French. The image inside the map neatline is georeferenced to the surface of the earth and fit to the Africa Sinusoidal projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads, territorial boundaries, shoreline features, and more. Relief shown pictorially. Includes also text and notes.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Africa, 1811 (Image 1 of 4) (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Africa, A. Arrowsmith. It was published by A. Arrowsmith, Soho Square. Additions to 1811. Scale [ca. 1:6,750,000]. This layer is image 1 of 4 total images of the four sheet source map, representing the northeast portion of the map. Covers also a small portion of Europe and the Middle East.The image inside the map neatline is georeferenced to the surface of the earth and fit to the Africa Sinusoidal projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, territorial boundaries, roads, shoreline features, and more. Relief shown by hachures. Includes notes.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Chester, England, ca. 1745 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Plan of the city & castle of Chester, survey'd and drawn by Alexander De Lavaux, engineer ; R. Parr sculp. It was published ca. 1745. Scale [ca. 1:3,960]. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'British National Grid' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, drainage, built-up areas and selected buildings, fortification, ground cover, and more. Relief shown by hachures.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Nova ac verissima Maris Caspii ante hac maximam fere partem nobis incogniti ac regionum adjacentium delineatio: jussu invictissimi principis Petri Alexii fil. magni Russorum imperatoris

immenso labore et maximis sumptibus facta, atque ex autographo in lucem edita per Reinerum Ottens geographum Amstelaedam ; Iacob Keyser sculp.

8-Ammonionaphthalene-2-sulfonate monohydrate : the zwitterionic hydrate of 1,7-Cleve's acid

The structure of 8-amino-2-naphthalenesulfonic acid monohydrate (1,7-Cleve's acid hydrate), C10H9NO3S.H2O, shows the presence of a sulfonate-aminium group zwitterion, both groups and the water molecule of solvation giving cyclic R3/3(8) intermolecular hydrogen-bonding interactions forming chains which extend down a axis of the unit cell. Additional peripheral associations, including weak aromatic ring pi-pi interactions [centroid-centroid distance 3.6299(15)A], result in a two-dimensional sheet structure.

Familial isolated hyperparathyroidism is linked to a 1.7 Mb region on chromosome 2p13.3-14

BACKGROUND: Familial isolated hyperparathyroidism (FIHP) is an autosomal dominantly inherited form of primary hyperparathyroidism. Although comprising only about 1% of cases of primary hyperparathyroidism, identification and functional analysis of a causative gene for FIHP is likely to advance our understanding of parathyroid physiology and pathophysiology. METHODS: A genome-wide screen of DNA from seven pedigrees with FIHP was undertaken in order to identify a region of genetic linkage with the disorder. RESULTS: Multipoint linkage analysis identified a region of suggestive linkage (LOD score 2.68) on chromosome 2. Fine mapping with the addition of three other families revealed significant linkage adjacent to D2S2368 (maximum multipoint LOD score 3.43). Recombination events defined a 1.7 Mb region of linkage between D2S2368 and D2S358 in nine pedigrees. Sequencing of the two most likely candidate genes in this region, however, did not identify a gene for FIHP. CONCLUSIONS: We conclude that a causative gene for FIHP lies within this interval on chromosome 2. This is a major step towards eventual precise identification of a gene for FIHP, likely to be a key component in the genetic regulation of calcium homeostasis.

Electromagnetic decay of the 1.7- and 2.43-MeV levels in ^9Be

The 1.7- and 2.43-MeV levels in ⁹Be were populated with the reaction ¹¹B(d, α)⁹Be* by bombarding thin boron on carbon foils with 1.7-MeV deuterons. The alpha particles were analyzed in energy with a surface-barrier counter set at the unique kinematically determined angle and the recoiling ⁹Be nuclei at 90^o were analyzed in rigidity with a magnetic spectrometer, in energy by a surface-barrier counter at the spectrometer focus, and in velocity by the time delay between an alpha and a ⁹Be count. When a pulse from the spectrometer counter was in the appropriate delayed coincidence with a pulse from the alpha counter, the two pulses were recorded in a two-dimensional pulse height analyzer. Most of the ⁹Be* decay by particle breakup. Only those that gamma decay are detected by the spectrometer counter. Thus the experiment provides a direct measurement of Γ_rad/Γ. Analysis of 384 observed events gives Γ_rad/Γ = (1.16 ± 0.14) X 10^-4 for the 2.43-MeV level. Combining this ratio with the value of Γ_rad = 0.122 ± 0.015 eV found from inelastic electron scattering gives Γ = (1.05 ± 0.18) keV. For the 1.7-MeV level, an upper limit, Γ_rad/Γ ≤ 2.4 = 10^-5, was determined.

Angiotensina 1-7-ren eragina giza espermatozoideen mugikortasunean eta Akt-ren fosforilazioan

Ang 1-7-ak duen eragina giza espermatozoideen mugikortasunean aztertu dugu, baita molekula honek Akt-ren fosforilazioan dituen efektuak ere. Bestalde, Mas hartzailearen presentzia espermatozoideetan ikertu dugu.

5，6-二羟基-2-（4-羟苯基）-4-酮-4H-1-苯并吡喃基-7-羟基-β-D-葡萄糖醛酸在制药中的应用

本发明提供化合物5，6-二羟基-2-(4-羟苯基)-4-酮-4H-1-苯并吡喃基-7-羟基-β-D-葡萄糖醛酸在制备抗艾滋病药物中和在制备逆转录酶抑制剂药物中的应用。

1MeVSi＋衬底加温注入Al（0.3）Ca（0.7）As/GaAs超晶格和GaAs的晶格损伤研究

用卢瑟福背散射沟道技术研究了1MeVSi~+在衬底加温和室温下以不同剂量注入Al＿(0．3)Ga＿(0．7)As／GaAs超晶格和GaAs后的晶格损伤。在衬底加温下, 观察到Al＿(0．3)Ga＿(0．7)As／GaAs超晶格和GaAs都存在一个动态退火速率与缺陷产生速率相平衡的剂量范围, 以及两种速率失去平衡的临界剂量。用热尖峰与碰撞模型解释了晶格损伤积累与注入剂量和衬底温度的关系。