969 resultados para One-pot


Relevância:

30.00% 30.00%

Publicador:

Resumo:

In recent years a great number of high speed railway bridges have been constructed within the Spanish borders. Due to the demanding high speed trains route's geometrical requirements, bridges frequently show remarkable lengths. This fact is the main reason why railway bridges are overall longer than roadway bridges. In the same line, it is also worth highlighting the importance of high speed trains braking forces compared to vehicles. While vehicles braking forces can be tackled easily, the railway braking forces demand the existence of a fixed-point. It is generally located at abutments where the no-displacements requirement can be more easily achieved. In some other cases the fixed-point is placed in one of the interior columns. As a consequence of these bridges' length and the need of a fixed-point, temperature, creep and shrinkage strains lead to fairly significant deck displacements, which become greater with the distance to the fixed-point. These displacements need to be accommodated by the piers and bearings deformation. Regular elastomeric bearings are not able to allow such displacements and therefore are not suitable for this task. For this reason, the use of sliding PTFE POT bearings has been an extensive practice mainly because they permit sliding with low friction. This is not the only reason of the extensive use of these bearings to high-speed railways bridges. The value of the vertical loads at each bent is significantly higher than in roadway bridges. This is so mainly because the live loads due to trains traffic are much greater than vehicles. Thus, gravel rails foundation represents a non-negligible permanent load at all. All this together increases the value of vertical loads to be withstood. This high vertical load demand discards the use of conventional bearings for excessive compressions. The PTFE POT bearings' higher technology allows to accommodate this level of compression thanks to their design. The previously explained high-speed railway bridge configuration leads to a key fact regarding longitudinal horizontal loads (such as breaking forces) which is the transmission of these loads entirely to the fixed-point alone. Piers do not receive these longitudinal horizontal loads since PTFE POT bearings displayed are longitudinally free-sliding. This means that longitudinal horizontal actions on top of piers will not be forces but imposed displacements. This feature leads to the need to approach these piers design in a different manner that when piers are elastically linked to superstructure, which is the case of elastomeric bearings. In response to the previous, the main goal of this Thesis is to present a Design Method for columns displaying either longitudinally fixed POT bearings or longitudinally free PTFE POT bearings within bridges with fixed-point deck configuration, applicable to railway and road vehicles bridges. The method was developed with the intention to account for all major parameters that play a role in these columns behavior. The long process that has finally led to the method's formulation is rooted in the understanding of these column's behavior. All the assumptions made to elaborate the formulations contained in this method have been made in benefit of conservatives results. The singularity of the analysis of columns with this configuration is due to a combination of different aspects. One of the first steps of this work was to study they of these design aspects and understand the role each plays in the column's response. Among these aspects, special attention was dedicated to the column's own creep due to permanent actions such us rheological deck displacements, and also to the longitudinally guided PTFE POT bearings implications in the design of the column. The result of this study is the Design Method presented in this Thesis, that allows to work out a compliant vertical reinforcement distribution along the column. The design of horizontal reinforcement due to shear forces is not addressed in this Thesis. The method's formulations are meant to be applicable to the greatest number of cases, leaving to the engineer judgement many of the different parameters values. In this regard, this method is a helpful tool for a wide range of cases. The widespread use of European standards in the more recent years, in particular the so-called Eurocodes, has been one of the reasons why this Thesis has been developed in accordance with Eurocodes. Same trend has been followed for the bearings design implications, which are covered by the rather recent European code EN-1337. One of the most relevant aspects that this work has taken from the Eurocodes is the non-linear calculations security format. The biaxial bending simplified approach that shows the Design Method presented in this work also lies on Eurocodes recommendations. The columns under analysis are governed by a set of dimensionless parameters that are presented in this work. The identification of these parameters is a helpful for design purposes for two columns with identical dimensionless parameters may be designed together. The first group of these parameters have to do with the cross-sectional behavior, represented in the bending-curvature diagrams. A second group of parameters define the columns response. Thanks to this identification of the governing dimensionless parameters, it has been possible what has been named as Dimensionless Design Curves, which basically allows to obtain in a reduced time a preliminary vertical reinforcement column distribution. These curves are of little use nowadays, firstly because each family of curves refer to specific values of many different parameters and secondly because the use of computers allows for extremely quick and accurate calculations.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

Research shows that consumers are readily embracing the Internet to buy products. This paper proposes that, in the case of grocery shopping, this may lead to sub-optimal decisions at the household level. Decisions online on what, where and from who to buy are normally taken by one individual. In the case of grocery shopping, decisions, however, need to be ‘vetted’ by ‘other’ individuals within the household. The ‘household wide related’ decisions influence how information technologies and systems for commerce should be designed and managed for optimum decision making. This paper argues, unlike previous research, that e-grocery retailing is failing to grow to its full potential not solely because of the ‘classical’ hazards and perceived risks associated with doing grocery shopping online but because e-grocery retailing strategy has failed to acknowledge the micro-household level specificities that affect decision making. Our exploratory research is based on empirical evidence which were collected through telephone interviews. We offer an insight into how e-grocery ‘fits’ and is ‘disrupted’ by the reality of day to day consumption decision making at the household level. Our main finding is to advocate a more role-neutral, multi-user and multi-technology approach to e-grocery shopping which re-defines the concept of the main shopper/decision maker thereby reconceptualising the ‘shopping logic’ for grocery products.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Background The problem of silent multiple comparisons is one of the most difficult statistical problems faced by scientists. It is a particular problem for investigating a one-off cancer cluster reported to a health department because any one of hundreds, or possibly thousands, of neighbourhoods, schools, or workplaces could have reported a cluster, which could have been for any one of several types of cancer or any one of several time periods. Methods This paper contrasts the frequentist approach with a Bayesian approach for dealing with silent multiple comparisons in the context of a one-off cluster reported to a health department. Two published cluster investigations were re-analysed using the Dunn-Sidak method to adjust frequentist p-values and confidence intervals for silent multiple comparisons. Bayesian methods were based on the Gamma distribution. Results Bayesian analysis with non-informative priors produced results similar to the frequentist analysis, and suggested that both clusters represented a statistical excess. In the frequentist framework, the statistical significance of both clusters was extremely sensitive to the number of silent multiple comparisons, which can only ever be a subjective "guesstimate". The Bayesian approach is also subjective: whether there is an apparent statistical excess depends on the specified prior. Conclusion In cluster investigations, the frequentist approach is just as subjective as the Bayesian approach, but the Bayesian approach is less ambitious in that it treats the analysis as a synthesis of data and personal judgements (possibly poor ones), rather than objective reality. Bayesian analysis is (arguably) a useful tool to support complicated decision-making, because it makes the uncertainty associated with silent multiple comparisons explicit.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The title compound catena-poly[aqua-mu3-2-nitrocinnamato], [Na(C9H6NO4)(H2O)2]n, the sodium salt of trans-2-nitrocinnamic acid, is a one-dimensional coordination polymer based on six-coordinate octahedral NaO6 centres comprising three facially-related monodentate carboxylate O-atom donors from separate ligands (all bridging)[Na-O, 2.4370(13)-2.5046(13)A] and three water molecules (two bridging, one monodentate) [Na-O, 2.3782(13)-2.4404(17)A]. The structure is also stabilized by intra-chain water-O-H...O(carboxylate) and O-H...O(nitro) hydrogen bonds.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The structures of the anhydrous 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid (DCPA) with the monocyclic heteroaromatic Lewis bases 2-aminopyrimidine, 3-(aminocarboxy) pyridine (nicotinamide) and 4-(aminocarbonyl) pyridine (isonicotinamide), namely 2-aminopyrimidinium 2-carboxy-4,5-dichlorobenzoate C4H6N3+ C8H3Cl2O4- (I), 3-(aminocarbonyl) pyridinium 2-carboxy-4,5-dichlorobenzoate C6H7N2O+ C8H3Cl2O4- (II) and the unusual salt adduct 4-(aminocarbonyl) pyridinium 2-carboxy-4,5-dichlorobenzoate 2-carboxymethyl-4,5-dichlorobenzoic acid (1/1/1) C6H7N2O+ C8H3Cl2O4-.C9H6Cl2O4 (III) have been determined at 130 K. Compound (I) forms discrete centrosymmetric hydrogen-bonded cyclic bis(cation--anion) units having both R2/2(8) and R2/1(4) N-H...O interactions. In compound (II) the primary N-H...O linked cation--anion units are extended into a two-dimensional sheet structure via amide-carboxyl and amide-carbonyl N-H...O interactions. The structure of (III) reveals the presence of an unusual and unexpected self-synthesized methyl monoester of the acid as an adduct molecule giving one-dimensional hydrogen-bonded chains. In all three structures the hydrogen phthalate anions are

Relevância:

20.00% 20.00%

Publicador:

Resumo:

While LRD (living donation to a genetically/emotionally related recipient) is well established in Australia, LAD (living anonymous donation to a stranger) is rare. Given the increasing use of LAD overseas, Australia may likely follow suit. Understanding the determinants of people’s willingness for LAD is essential but infrequently studied in Australia. Consequently, we compared the determinants of people’s LRD and LAD willingness, and assessed whether these determinants differed according to type of living donation. We surveyed 487 health students about their LRD and LAD willingness, attitudes, identity, prior experience with blood and organ donation, deceased donation preference, and demographics. We used Structural Equation Modelling (SEM) to identify the determinants of willingness for LRD and LAD and paired sample t-tests to examine differences in LRD and LAD attitudes, identity, and willingness. Mean differences in willingness (LRD 5.93, LAD 3.92), attitudes (LRD 6.43, LAD 5.53), and identity (LRD 5.69, LAD 3.58) were statistically significant. Revised SEM models provided a good fit to the data (LRD: x2 (41) = 67.67, p = 0.005, CFI = 0.96, RMSEA = 0.04; LAD: x2 (40) = 79.64, p < 0.001, CFI = 0.95, RMSEA = 0.05) and explained 45% and 54% of the variation in LRD and LAD willingness, respectively. Four common determinants of LRD and LAD willingness emerged: identity, attitude, past blood donation, and knowing a deceased donor. Religious affiliation and deceased donation preference predicted LAD willingness also. Identifying similarities and differences in these determinants can inform future efforts aimed at understanding people’s LRD and LAD willingness and the evaluation of potential living donor motives. Notably, this study highlights the importance of people’s identification as a living donor as a motive underlying their willingness to donate their organs while living.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Brand loyalty is a concept that has garnered considerable interest over recent years from both marketing practitioners and academics alike. While marketers are primarily interested in ways they can generate and increase brand loyalty from their customers, academics strive to conducts research which investigates the antecedents and consequences of customer loyalty (See DeWitt, Nguyen and Marshall 2008; Russell-Bennett, McColl-Kennedy and Coote 2007).

Relevância:

20.00% 20.00%

Publicador:

Resumo:

We consider one-round key exchange protocols secure in the standard model. The security analysis uses the powerful security model of Canetti and Krawczyk and a natural extension of it to the ID-based setting. It is shown how KEMs can be used in a generic way to obtain two different protocol designs with progressively stronger security guarantees. A detailed analysis of the performance of the protocols is included; surprisingly, when instantiated with specific KEM constructions, the resulting protocols are competitive with the best previous schemes that have proofs only in the random oracle model.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

We consider one-round key exchange protocols secure in the standard model. The security analysis uses the powerful security model of Canetti and Krawczyk and a natural extension of it to the ID-based setting. It is shown how KEMs can be used in a generic way to obtain two different protocol designs with progressively stronger security guarantees. A detailed analysis of the performance of the protocols is included; surprisingly, when instantiated with specific KEM constructions, the resulting protocols are competitive with the best previous schemes that have proofs only in the random oracle model.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

We consider one-round key exchange protocols secure in the standard model. The security analysis uses the powerful security model of Canetti and Krawczyk and a natural extension of it to the ID-based setting. It is shown how KEMs can be used in a generic way to obtain two different protocol designs with progressively stronger security guarantees. A detailed analysis of the performance of the protocols is included; surprisingly, when instantiated with specific KEM constructions, the resulting protocols are competitive with the best previous schemes that have proofs only in the random oracle model.