Estudo da influência da adição de borracha vulcanizada em concreto à temperatura ambiente e elevada temperatura

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Desenvolvimento de compósitos PEUAPM / apatitas para substituição e regeração óssea

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo de aproveitamento do resíduo do beneficiamento de caulim como matéria prima na produção de pozolanas para cimentos compostos e pozolânicos

O emprego de resíduos na construção civil pode vir a se tornar uma atividade de extrema importância e mais freqüente, principalmente, pela quantidade disponível com potencialidades de reciclagem, possibilitando minimização dos impactos ambientais. As indústrias que beneficiam o caulim para ser utilizado na indústria de papel são responsáveis por gerar dois tipos de resíduos. Um deles, o resíduo contendo o argilomineral caulinita, apresenta potencialidade de ser utilizado como pozolanas na indústria da construção civil. Essa pesquisa avaliou a viabilidade técnica de produção de pozolanas provenientes de misturas de diversos percentuais do resíduo caulinítico com calcário, com vistas a incrementar a reatividade. Estudou-se os teores de substituição de cimento pelas pozolanas em 10%, 20%, 30%, 40%, 50% e 60%. O cimento utilizado foi do tipo CP I S 32 e as pozolanas foram produzidas em laboratório. Foram realizados os seguintes ensaios nos cimentos experimentais: massa específica, área superficial específica, água de consistência normal da pasta, tempo de pega e resistência à compressão. Nas pozolanas, além das análises química e física, foram realizados ensaios mineralógicos. Baseando-se nos resultados encontrados e na literatura técnica, observou-se que a fabricação da pozolana mostrou-se eficaz, pois permitiu aos cimentos alcançar resistências à compressão muito maiores à referência mesmo com teores elevados de incorporação. É lícito concluir que a incorporação do calcário na calcinação do resíduo proveniente do beneficiamento do caulim confirmou ser uma excelente alternativa na produção de pozolanas de alta reatividade, podendo ser empregadas como adições minerais aos cimentos compostos ou pozolânicos substituindo argilas naturais calcinadas e principalmente na fabricação de elementos pré-fabricados em conjunto com fibras em geral.

Influência do teor de cinza volante na reologia de argamassa de assentamento: fabricado com reciclagem de resíduos

As argamassas podem ser consideradas como um conjunto de partículas sólidas em suspensão (agregado miúdo), aglomerantes e água (pasta de cimento). Sendo assim, seu comportamento reológico durante a cura pode ser influenciado por fatores como a granulometria, composição e teor de água incorporado. Este trabalho estudou as características reológicas de seis composições de argamassas, em função do teor de cinza volante, como material de atividade pozolânica, em substituição parcial do cimento. A argamassa estudada utilizou como base agregado o resíduo da construção civil (RCC), devidamente caracterizado por difratometria e fluorescência de raios-X. Formularam-se composições de argamassas para os ensaios reológicos com adição de resíduo de construção civil (RCC) nas proporções de 95, 90, 85, 80, 75 e 70%; cinzas volantes (CV) 0, 5, 10, 15, 20 e 25% e 5% de Cimento Portland Comum (CP II- E 32), sendo que em cada amostra foi incorporado 35% de água. Utilizou-se o viscosímetro modelo VT 550, com sensor tipo cilindros coaxiais SV₁ – Haake a temperatura de 28ºC. Para avaliar o tempo de cura do material programou-se uma taxa de cisalhamento constante 53,4 s^-1 em 1h e 45min, sendo avaliado o torque em intervalos de 15min. Para a elaboração das curvas de fluxo e curvas de histerese, utilizou-se a taxa de cisalhamento entre 0 e 600 s^-1 no intervalo de tempo de 120s. Os resultados mostraram que a incorporação de cinza volante foi o principal fator para aumento do torque no tempo de cura das argamassas e mudança do comportamento de reópetico para tixotrópico, nos traços analisados. Os dados experimentais das formulações propostas ajustaram-se ao modelo reológico de Herschel-Bulkley.

Enzyme replacement therapy for Mucopolysaccharidosis Type I among patients followed within the MPS Brazil Network

Mucopolysaccharidosis type I (MPS I) is a rare lysosomal disorder caused by deficiency of alpha-L-iduronidase. Few clinical trials have assessed the effect of enzyme replacement therapy (ERT) for this condition. We conducted an exploratory, open-label, non-randomized, multicenter cohort study of patients with MPS I. Data were collected from questionnaires completed by attending physicians at the time of diagnosis (T1; n = 34) and at a median time of 2.5 years later (T2; n = 24/34). The 24 patients for whom data were available at T2 were allocated into groups: A, no ERT (9 patients; median age at T1 = 36 months; 6 with severe phenotype); B, on ERT (15 patients; median age at T1 = 33 months; 4 with severe phenotype). For all variables in which there was no between-group difference at baseline, a delta of ≥ ± 20% was considered clinically relevant. The following clinically relevant differences were identified in group B in T2: lower rates of mortality and reported hospitalization for respiratory infection; lower frequency of hepatosplenomegaly; increased reported rates of obstructive sleep apnea syndrome and hearing loss; and stabilization of gibbus deformity. These changes could be due to the effect of ERT or of other therapies which have also been found more frequently in group B. Our findings suggest MPS I patients on ERT also receive a better overall care. ERT may have a positive effect on respiratory morbidity and overall mortality in patients with MPS I. Additional studies focusing on these outcomes and on other therapies should be performed.

Mucopolysaccharidoses in northern Brazil: targeted mutation screening and urinary glycosaminoglycan excretion in patients undergoing enzyme replacement therapy

Mucopolysaccharidoses (MPS) are rare lysosomal disorders caused by the deficiency of specific lysosomal enzymes responsible for glycosaminoglycan (GAG) degradation. Enzyme Replacement Therapy (ERT) has been shown to reduce accumulation and urinary excretion of GAG, and to improve some of the patients' clinical signs. We studied biochemical and molecular characteristics of nine MPS patients (two MPS I, four MPS II and three MPS VI) undergoing ERT in northern Brazil. The responsiveness of ERT was evaluated through urinary GAG excretion measurements. Patients were screened for eight common MPS mutations, using PCR, restriction enzyme tests and direct sequencing. Two MPS I patients had the previously reported mutation p.P533R. In the MPS II patients, mutation analysis identified the mutation p.R468W, and in the MPS VI patients, polymorphisms p.V358M and p.V376M were also found. After 48 weeks of ERT, biochemical analysis showed a significantly decreased total urinary GAG excretion in patients with MPS I (p < 0.01) and MPS VI (p < 0.01). Our findings demonstrate the effect of ERT on urinary GAG excretion and suggest the adoption of a screening strategy for genotyping MPS patients living far from the main reference centers.

Assessing the replacement of lead in solders: effects on resource use and human health

Human health and environmental concerns are not usually considered at the same time. Tin-lead solders are still widely used in several countries, including Brazil, by manufacturers of electronic assemblies. One of the options to reduce or eliminate lead from the manufacturing environment is its replacement with lead-free alloys. This paper applies emergy synthesis and the DALY indicator (Disability Adjusted Life Years) to assess the impact of manufacturing soft solder using tin, lead and other metals on the environment and on human health. The results are presented together with the company's financial results and the results calculated from the Brazilian statistical value of life. The calculation of emergy per unit showed that more resources are used to produce one ton of lead-free solders than to produce one ton of tin-lead solders, with and without the use of consumer waste recovered through a reverse logistics system. The assessment of air emissions during solder production shows that the benefits of the lead-free solution are limited to the stages of manufacturing and assembling. The tin-lead solder appears as the best option in terms of resource use efficiency and with respect to emissions into the atmosphere when the mining stage is included. A discussion on the influence of the system's boundaries on the decision-making process for materials substitution is presented. (C) 2012 Elsevier Ltd. All rights reserved.

Properties of Mortar Using Cubes, Prism Halves, and Cylinder Specimens

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Effects of catecholamines on volemic replacement with saline solution and the impact on heart rate variability in rabbits subjected to hemorrhage. A study by spectral analysis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mini-implants as provisional anchorage for the replacement of missing anterior teeth: A clinical report

This clinical report describes an adult patient referred for orthodontic treatment with mini-implants as anchorage to correct the root angulation of maxillary lateral incisors. The purpose of this report was to demonstrate the versatility of mini-implants placed in a vertical direction in esthetic areas. During orthodontic treatment, some aspects must be observed to preserve the interim restoration against the occlusal loads to avoid screw fracture. A fixed appliance was placed to correct the position of the maxillary anterior teeth and to complete the treatment. Acceptable esthetics and function were achieved.

Effects of neem oil (Azadirachta indica A. Juss) on the replacement of the midgut epithelium in the lacewing Ceraeochrysa claveri during larval-pupal metamorphosis

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Impact of gestational diabetes and lactational insulin replacement on structure and secretory function of offspring rat ventral prostate

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Use of a cashew nut shell liquid resin as a potential replacement for phenolic resins in the preparation of panels - a review

The Cashew Nut Shell Liquid (CNSL) can be considered as a versatile raw material with wide applications in the form of surface coatings, paints and varnishes, as well as the production of polymers. Within this context, the chemical constituents of CNSL (anarcadic acid, cardanol, 2-cardol and methylcardol) become promising in the development of new materials components. Once separated, CNSL can be used in the research and development of additives, surfactants, pharmaceuticals, pesticides, polymers, resins and others. Being a byproduct, CNSL used in the preparation of new materials is characterized as a truly technological innovation.

Effects of dexmedetomidine on pulse pressure variation changes induced by hemorrhage followed by volume replacement in isoflurane-anesthetized dogs

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Durabilidade da argamassa mista de revestimento interno contendo dregs-grits em substituição à areia

This paper concerns about the durability of new material in construction. It is noteworthy the fact that increases increasingly searching for alternative materials that do not depend only of natural resources and at the same time be an alternative for reuse of industrial waste. Since the construction materials have a long life and a high cost of civil works and maintenance, it is crucial to estimate the behavior of a new product. Thus , this work discuss the durability of mixed mortar lining , made with waste from the process Kraft pulp production , known as dregs and grits , in partial replacement of sand. Tests were conducted to simulate conditions as adverse environments of constant heat and fire, with the aim of analyzing the behavior of mortar mixed matched the behavior of standard mortar